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Methods in Molecular Biology, ISSN 1064-3745, 2015, Volume 1226, pp. 117 - 130
Strain engendered within bone tissue by mechanical loading of the skeleton is a major influence on the processes of bone modeling and remodeling and so a... 
Osteoblast | Bone | Mechanical loading | Mechanobiology | Four-point bending | Strain | Stress, Physiological - physiology | Osteogenesis - physiology | Animals | Cell Proliferation - physiology | Cells, Cultured | Mice | Osteoblasts - cytology | Osteoblasts - metabolism | Cell Culture Techniques - methods | Weight-Bearing - physiology | Index Medicus
Journal Article
Bone, ISSN 8756-3282, 2016
Abstract Mechanical loading is the primary functional determinant of bone mass and architecture, and osteocytes play a key role in translating mechanical... 
Orthopedics
Journal Article
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 08/2011, Volume 585, Issue 15, pp. 2450 - 2454
► down-regulation is stimulated by mechanical strain in osteoblastic cells. ► /Osteocalcin regulation by strain in Saos2 osteoblastic cells requires Cox2. ►... 
Osteoporosis | Sclerostin | PGE2 signaling | Mechanical strain | parathyroid hormone | extracellular signal-regulated kinase | BMP | PTH | prostaglandin | TCS | quantitative reverse transcriptase polymerase chain reaction | qRT-PCR | PKA | PKC | mitogen activated protein kinase | MAPK | bone morphogenetic protein | Cox | TCS2510 | cyclo-oxygenase | protein kinase A | protein kinase C | ERK | ACTIVATION | STIMULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EARLY RESPONSES | CELL BIOLOGY | BIOPHYSICS | BONE-FORMATION | ESTROGEN-RECEPTOR-ALPHA | IN-VIVO | SELECTIVE AGONIST | EXPRESSION | PROSTAGLANDIN E-2 | MODULATION | Dinoprostone - metabolism | Biomechanical Phenomena | Signal Transduction | Genetic Markers - genetics | Humans | Cells, Cultured | Stress, Mechanical | Osteoblasts - metabolism | Bone Morphogenetic Proteins - genetics | Down-Regulation - genetics | Receptors, Prostaglandin E, EP4 Subtype - metabolism | Parathyroid hormone | Prostaglandins E | DNA polymerases | Bone morphogenetic proteins | Mitogens | Protein kinases | Index Medicus | PG, prostaglandin | qRT-PCR, quantitative reverse transcriptase polymerase chain reaction | PKC, protein kinase C | TCS, TCS2510 | PTH, parathyroid hormone | Cox, cyclo-oxygenase | ERK, extracellular signal-regulated kinase | BMP, bone morphogenetic protein | MAPK, mitogen activated protein kinase | PKA, protein kinase A
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, pp. e0140260 - e0140260
Genome Wide Association Studies suggest that Wnt16 is an important contributor to the mechanisms controlling bone mineral density, cortical thickness, bone... 
OSTEOCYTES | MINERAL DENSITY | OSTEOGENIC RESPONSE | MULTIDISCIPLINARY SCIENCES | GROWTH | GENE-EXPRESSION | GENOME-WIDE | LOAD-BEARING | MUTATIONS | RECEPTOR-ALPHA | BETA | Estrogens - pharmacology | Ovariectomy | Mice, Inbred C57BL | Male | Tibia - drug effects | Wnt Proteins - metabolism | Gene Expression Regulation - drug effects | Animals | Wnt Proteins - genetics | Osteoporosis - metabolism | Estrogen Receptor alpha - metabolism | Female | Osteoporosis - genetics | Weight-Bearing | Mice | Tibia - metabolism | Estrogens - metabolism | Osteoporosis - physiopathology | Tibia - physiopathology | Aging - metabolism | Osteoporosis | Physiological aspects | Bones | Genetic aspects | Research | Wnt proteins | Density | Risk factors | Estrogens | Genomes | Males | Osteoblasts | Estradiol | Biomedical materials | Tibia | Mechanical loading | Rodents | Cooperation | Bone marrow | Aging | Biocompatibility | Bone loss | Bone (cortical) | Bone strength | Age | Medical research | Kidneys | Mechanical unloading | Unloading | Mechanical properties | Tamoxifen | Gene expression | Nutrition research | Sex hormones | Bone mass | Osteoclasts | Bone mineral density | Mutation | Females | Index Medicus | CORTICAL BONE | FEMALE MICE | Cell and Molecular Biology | MALE-MICE | KAPPA-B | OSTEOGENIC | RESPONSE | Cell- och molekylärbiologi
Journal Article
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