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Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1582 - 1582
Abstract Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin lymphoma characterized by rapid disease progression. Although the clinical outcome of... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 4134 - 4134
Abstract Effector CD8+ T cells play a crucial role in anti-tumor immunity. Two major subsets of effector CD8+ T cells have been identified based on expression... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1590 - 1590
Abstract T cell Ig and ITIM domain (TIGIT) is an immune checkpoint molecule that is expressed on a variety of cell types including NK cells, effector and... 
Journal Article
Oncotarget, ISSN 1949-2553, 09/2017, Volume 8, Issue 37, pp. 61425 - 61439
Exhausted T-cells in follicular lymphoma (FL) typically express PD-1, but expression of PD-1 is not limited to exhausted cells. Although expected to be... 
Follicular lymphoma | Immune checkpoint | T-cell exhaustion | LAG-3 | PD-1 | SURVIVAL | IMMUNITY | follicular lymphoma | PD-L1 EXPRESSION | CHRONIC VIRAL-INFECTION | CANCER | CELL BIOLOGY | CXC CHEMOKINE RECEPTOR-5 | immune checkpoint | NON-HODGKINS-LYMPHOMA | TIM-3 | CLASS-II | DISEASE PROGRESSION
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 1772 - 1772
Abstract Waldenstrom's Macroglobulinemia (WM) is an indolent B-cell malignancy that is characterized by bone marrow infiltration of lymphoplasmacytic cells and... 
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2790 - 2790
The outcomes of lymphoma patients treated with PD1 inhibitors (PD1i) vary significantly across different histologies with objective responses rates that are... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 2661 - 2661
Abstract T-cell exhaustion plays an important role in attenuating the function of immune cells in B-cell non-Hodgkin's lymphoma (NHL) and PD-1 expression is... 
Journal Article
Cell Reports, ISSN 2211-1247, 02/2019, Volume 26, Issue 8, pp. 2178 - 2193.e3
Follicular lymphoma (FL) is an indolent B cell malignancy characterized by an extensive but poorly functional T cell infiltrate in the tumor microenvironment.... 
patient survival | follicular lymphoma | co-stimulatory receptor | immune signature | intratumoral CD4+ T cell | CD27 | mass cytometry | CD4+CD25+ regulatory T cells | CyTOF | PD-1 | T cell | intratumoral CD4 | regulatory T cells | CD4 | CD25 | HETEROGENEITY | TRANSFORMATION | CD28 EXPRESSION | MICROENVIRONMENT | DISTINCT | CD70 EXPRESSION | FLOW-CYTOMETRY | LINEAGE | EXHAUSTION | LYMPHOCYTES | CELL BIOLOGY
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 3875 - 3875
Abstract Regulatory T-cells (TREG) are the gateway to immune function and typically regulate immune cell activation. Cytokines, including interleukin-2 (IL-2),... 
Journal Article
Cancer Cell, ISSN 1535-6108, 2007, Volume 12, Issue 2, pp. 131 - 144
Activation of NF-κB has been noted in many tumor types, however only rarely has this been linked to an underlying genetic mutation. An integrated analysis of... 
CELLCYCLE | SIGNALING | RESPONSES | HUMAN GENOME | ONCOLOGY | TRANSLOCATIONS | COPY NUMBER | KINASE | SPLENIC MICROARCHITECTURE | MICE | EXPRESSION | CANCER | LYMPHOID MALIGNANCIES
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14_Supplement, pp. 3287 - 3287
BACKGROUND 
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 3287 - 3287
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 140 - 140
Abstract Long non-coding RNAs (lncRNA) are key regulatory RNAs that do not code for protein. Recently lncRNAs have been recognized as key regulators of gene... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 2515 - 2515
Abstract BACKGROUND Monocytes and macrophages (mo/mΦ) are a key part of the composition of peripheral blood (PB) and tissues and increased numbers of mo/mΦ... 
Journal Article
BLOOD CANCER JOURNAL, ISSN 2044-5385, 10/2019, Volume 9, Issue 10, pp. 1 - 14
Signal regulatory protein-Phi (SIRP Phi) is a key member of the "do-not-eat-me" signaling pathway, but its biological role and clinical relevance in B-cell NHL... 
SURVIVAL | CELLS | ACTIVATION | ONCOLOGY | RITUXIMAB | TUMOR-ASSOCIATED MACROPHAGES | TIME | COUNT PREDICTS | HEMATOLOGY | CONTRIBUTES | SIGNAL REGULATORY PROTEIN | Lymphomas
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 586 - 586
Abstract Introduction: Given the established role of PD-1 in mediating immune suppression in chronic lymphocytic leukemia (CLL), we tested and reported the... 
Journal Article
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