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Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 5378 - 13
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 17257 - 13
Non-alcoholic fatty liver disease (NAFLD) is a leading form of chronic liver disease with large unmet need. Non-alcoholic steatohepatitis (NASH), a progressive... 
DIABETES-MELLITUS | RECRUITMENT | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | CONNECTIVITY MAP | DISEASE | NONALCOHOLIC STEATOHEPATITIS | MODEL | PREVALENCE | EXPRESSION | ASSOCIATION | Cirrhosis | Fatty liver | Molecular modelling | Liver diseases | Transcription | Computer applications | Fibrosis | Hepatocellular carcinoma | Interferon | Gene expression | Ribonucleic acid--RNA | Cholesterol
Journal Article
European journal of immunology, ISSN 0014-2980, 06/2019
Changes in the epigenetic landscape of immune cells are a crucial component of gene activation during the induction of inflammatory responses, therefore it has... 
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 09/2018, Volume 25, Issue 9, pp. 885 - 893
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2018, Volume 61, Issue 18, pp. 8321 - 8336
ATAD2 is a cancer-associated protein whose bromodomain has been described as among the least druggable of its class. In our recent disclosure of the first... 
COREGULATOR ANCCA | BREAST-CANCER | PROSTATE | BROMODOMAIN INHIBITORS | ANDROGEN RECEPTOR | OVEREXPRESSION | CHEMISTRY, MEDICINAL | PROGRESS | GENES | CHEMICAL PROBES | FAMILY
Journal Article
ChemMedChem, ISSN 1860-7179, 02/2019, Volume 14, Issue 4, pp. 361 - 361
The Cover Feature shows a CREBBP bromodomain surface as a representative non‐BET bromodomain together with high‐quality bromodomain probe molecules GNE‐781,... 
acetylated lysines | chemical probes | non-BET bromodomains | target validation | epigenetics
Journal Article
Science, ISSN 0036-8075, 06/2017, Volume 356, Issue 6345, p. 1397
The success of new therapies hinges on our ability to understand their molecular and cellular mechanisms of action. We modified BET bromodomain inhibitors, an... 
Epigenetic inheritance | Enzyme inhibitors | Patient outcomes | Chemical properties | Gene therapy | Health aspects | Testing
Journal Article
PLoS Biology, ISSN 1544-9173, 12/2015, Volume 13, Issue 12
  Trypanosoma brucei, the causative agent of African sleeping sickness, is transmitted to its mammalian host by the tsetse. In the fly, the parasite's surface... 
Proteins | Protozoa | Immunoglobulins | Data collection | Parasites | Mammals | Gene expression | Experiments | Crystal structure
Journal Article
Molecular Cell, ISSN 1097-2765, 08/2013, Volume 51, Issue 3, pp. 310 - 325
Journal Article
European Journal of Immunology, ISSN 0014-2980, 01/2015, Volume 45, Issue 1, pp. 287 - 297
Journal Article
Nature, ISSN 0028-0836, 10/2011, Volume 478, Issue 7370, pp. 529 - 533
Journal Article