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1. Full Text Clinical and demographic correlates of medication and visit adherence in a large randomized controlled trial
by Whittle, Jeff and Yamal, José-Miguel and Williamson, Jeffrey D and Ford, Charles E and Probstfield, Jeffrey L and Beard, Barbara L and Marginean, Horia and Hamilton, Bruce P and Suhan, Pamela S and Davis, Barry R and ALLHAT Collaborative Res Grp and ALLHAT Collaborative Research Group and on behalf of the ALLHAT Collaborative Research Group
BMC Health Services Research, ISSN 1472-6963, 07/2016, Volume 16, Issue 1, p. 236
Background: Patient characteristics are associated with adherence, which has implications for planning clinical research or designing payment systems that... 
Adherence | Angiotensin-converting enzyme inhibitors | Hypertension | Hyperlipidemia | Calcium channel blockers | Race | Diuretics | LIPID-LOWERING TREATMENT | ALLHAT | HEALTH-CARE COSTS | HYPERTENSIVE PATIENTS | DIABETES-MELLITUS | CHRONIC DISEASE | HEALTH CARE SCIENCES & SERVICES | INITIAL-DRUG CHOICE | PHARMACY RECORDS | ANTIHYPERTENSIVE THERAPY | MAJOR OUTCOMES | Medication Adherence - statistics & numerical data | Chlorthalidone - therapeutic use | Demography | Double-Blind Method | Humans | Middle Aged | Hypertension - drug therapy | Male | Treatment Outcome | Antihypertensive Agents - therapeutic use | North America | Amlodipine - therapeutic use | Patient Compliance - statistics & numerical data | Lisinopril - therapeutic use | Myocardial Infarction - drug therapy | Female | Aged | Appointments and Schedules | Retrospective Studies | African Continental Ancestry Group | Patient compliance | Analysis | Physician services utilization | Studies | Health maintenance organizations--HMOs | Statistical analysis | Clinics | Review boards | Consent | Cardiovascular disease | Blood pressure | Behavior | Acquisitions & mergers
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2. Full Text Lixisenatide in type 2 diabetes and acute coronary syndrome: The authors reply
by Pfeffer, Marc A and Claggett, Brian and Probstfield, Jeffrey L
New England Journal of Medicine, ISSN 0028-4793, 03/2016, Volume 374, Issue 11, pp. 1095 - 1096
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3. Full Text Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome
by Pfeffer, Marc A and Claggett, Brian and Diaz, Rafael and Dickstein, Kenneth and Gerstein, Hertzel C and Køber, Lars V and Lawson, Francesca C and Ping, Lin and Wei, Xiaodan and Lewis, Eldrin F and Maggioni, Aldo P and McMurray, John J.V and Probstfield, Jeffrey L and Riddle, Matthew C and Solomon, Scott D and Tardif, Jean-Claude and ELIXA Investigators
The New England Journal of Medicine, ISSN 0028-4793, 12/2015, Volume 373, Issue 23, pp. 2247 - 2257
In this randomized study, the addition of lixisenatide, a glucagon-like peptide 1–receptor agonist, to usual care in patients with type 2 diabetes and a recent... 
MEDICINE, GENERAL & INTERNAL | GLYCEMIC CONTROL | GLUCAGON-LIKE PEPTIDE-1 | MYOCARDIAL-INFARCTION | CARDIOVASCULAR OUTCOMES | RECEPTOR AGONISTS | GLUCOSE | DOUBLE-BLIND | FOLLOW-UP | MELLITUS | CONGESTIVE-HEART-FAILURE | Glycated Hemoglobin A - analysis | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Kaplan-Meier Estimate | Proportional Hazards Models | Male | Acute Coronary Syndrome - drug therapy | Myocardial Infarction - complications | Acute Coronary Syndrome - complications | Angina, Unstable - complications | Diabetes Mellitus, Type 2 - mortality | Treatment Failure | Cardiovascular Diseases - epidemiology | Female | Aged | Diabetes Mellitus, Type 2 - drug therapy | Hypoglycemic Agents - adverse effects | Diabetes Mellitus, Type 2 - complications | Glucagon-Like Peptide-1 Receptor - agonists | Peptides - adverse effects | Peptides - therapeutic use | Type 2 diabetes | Treatment outcome | Care and treatment | Analysis | Hypoglycemic agents | Dosage and administration | Acute coronary syndrome | Myocardial infarction | Cerebral infarction | Glucagon | Diabetes mellitus | Hypersensitivity | Pancreatitis | Angina | Glucose | Hypoglycemia | Morbidity | Studies | Heart rate | Diabetes | Acute coronary syndromes | Cardiovascular diseases | Pancreas | Drug therapy | Diabetes mellitus (non-insulin dependent) | Heart diseases | Glucagon-like peptide 1 | Clinical trials | Regulatory approval | Hemoglobin | Drug dosages | Heart failure | Mortality
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4. Full Text Glucose variability in a 26-week randomized comparison of mealtime treatment with rapid-acting insulin versus GLP-1 agonist in participants with type 2 diabetes at high cardiovascular risk
by O'Brien, Kevin D and Hirsch, Irl B and Riddle, Matthew C and Probstfield, Jeffrey L
Diabetes Care, ISSN 0149-5992, 10/2016, Volume 39, Issue 10, p. e188
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5. Full Text Spironolactone for Heart Failure with Preserved Ejection Fraction
by Pitt, Bertram and Pfeffer, Marc A and Assmann, Susan F and Boineau, Robin and Anand, Inder S and Claggett, Brian and Clausell, Nadine and Desai, Akshay S and Diaz, Rafael and Fleg, Jerome L and Gordeev, Ivan and Harty, Brian and Heitner, John F and Kenwood, Christopher T and Lewis, Eldrin F and O'Meara, Eileen and Probstfield, Jeffrey L and Shaburishvili, Tamaz and Shah, Sanjiv J and Solomon, Scott D and Sweitzer, Nancy K and Yang, Song and McKinlay, Sonja M and Topcat Investigators and TOPCAT Investigators
The New England Journal of Medicine, ISSN 0028-4793, 04/2014, Volume 370, Issue 15, pp. 1383 - 1392
In this trial, 3445 patients with heart failure and a preserved ejection fraction were assigned to spironolactone or placebo. At a mean of 3.3 years, there was... 
MORTALITY | TRIAL | PERINDOPRIL | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | TASK-FORCE | REDUCTION | QUALITY-OF-LIFE | OUTCOMES | VENTRICULAR DYSFUNCTION | HOSPITALIZATION | Double-Blind Method | Follow-Up Studies | Humans | Middle Aged | Heart Failure - physiopathology | Kaplan-Meier Estimate | Hospitalization - statistics & numerical data | Mineralocorticoid Receptor Antagonists - adverse effects | Male | Heart Failure - drug therapy | Incidence | Mineralocorticoid Receptor Antagonists - therapeutic use | Stroke Volume | Treatment Failure | Aged, 80 and over | Cardiovascular Diseases - mortality | Female | Aged | Spironolactone - therapeutic use | Spironolactone - adverse effects | Heart Failure - mortality | Heart failure | Prevention | Evaluation | Care and treatment | Usage | Spironolactone | Mortality | United Kingdom | Cardiac output | Creatinine | Hyperkalemia | Heart attacks | Hypokalemia | Ventricle | Drug therapy | Heart diseases | Patients | Clinical outcomes
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6. Full Text Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy
by Boden, William E and Probstfield, Jeffrey L and Anderson, Todd and Chaitman, Bernard R and Desvignes-Nickens, Patrice and Koprowicz, Kent and McBride, Ruth and Teo, Koon and Weintraub, William and The AIM-HIGH Investigators and AIM-HIGH Investigators
The New England Journal of Medicine, ISSN 0028-4793, 12/2011, Volume 365, Issue 24, pp. 2255 - 2267
In this clinical trial involving patients with established cardiovascular disease, the addition of niacin to intensive statin therapy provided no additional... 
LDL CHOLESTEROL | MEDICINE, GENERAL & INTERNAL | DENSITY-LIPOPROTEIN CHOLESTEROL | IMPACT | CARDIOVASCULAR EVENTS | ATHEROSCLEROSIS | CORONARY-HEART-DISEASE | COMBINATION | ARTERIAL BIOLOGY | EXTENDED-RELEASE NIACIN | SECONDARY PREVENTION | Simvastatin - therapeutic use | Humans | Middle Aged | Male | Niacin - therapeutic use | Treatment Failure | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Niacin - adverse effects | Cholesterol, LDL - blood | Female | Brain Ischemia - chemically induced | Muscular Diseases - chemically induced | Drug Therapy, Combination | Brain Ischemia - epidemiology | Hypolipidemic Agents - adverse effects | Atherosclerosis - drug therapy | Kaplan-Meier Estimate | Proportional Hazards Models | Atherosclerosis - blood | Medication Adherence | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Triglycerides - blood | Cholesterol, HDL - blood | Aged | Hypolipidemic Agents - therapeutic use | Drugs | Dose-response relationship (Biochemistry) | Control | Dosage and administration | Product/Service Evaluations | Drug therapy | Niacin | Cholesterol | Statins | Myocardial infarction | Cerebral infarction | Lipoproteins (low density) | Stroke | Simvastatin | Cardiovascular disease | Triglycerides | Coronary artery disease | Ischemia | Diet | Arteriosclerosis | Atherosclerosis | Cardiovascular diseases | Lipoproteins (high density) | Heart diseases
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7. Full Text The authors reply
by Boden, William E and Probstfield, Jeffrey L and McBride, Ruth
New England Journal of Medicine, ISSN 0028-4793, 03/2012, Volume 366, Issue 13, pp. 1255 - 1256
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8. Full Text Strategies for Recruitment and Retention of Participants in Clinical Trials
by Probstfield, Jeffrey L and Frye, Robert L
JAMA, ISSN 0098-7484, 10/2011, Volume 306, Issue 16, pp. 1798 - 1799
The article discusses some of the critical barriers to the successful recruitment and retention of participants in clinical trials. Various strategies for... 
MEDICINE, GENERAL & INTERNAL | Clinical Trials as Topic - economics | United States | Health Personnel | Humans | Professional Role | Organizational Policy | Patient Dropouts | Health Knowledge, Attitudes, Practice | Patient Selection | Medical personnel | Clinical trials | Research ethics | Research grants | Management | Laws, regulations and rules | Participants | Retention | Clinical outcomes | Recruitment
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9. Full Text Effect of Selenium and Vitamin E on Risk of Prostate Cancer and Other Cancers: The Selenium and Vitamin E Cancer Prevention Trial (SELECT)
by Lippman, Scott M and Klein, Eric A and Goodman, Phyllis J and Lucia, M. Scott and Thompson, Ian M and Ford, Leslie G and Parnes, Howard L and Minasian, Lori M and Gaziano, J. Michael and Hartline, Jo Ann and Parsons, J. Kellogg and Bearden, James D and Crawford, E. David and Goodman, Gary E and Claudio, Jaime and Winquist, Eric and Cook, Elise D and Karp, Daniel D and Walther, Philip and Lieber, Michael M and Kristal, Alan R and Darke, Amy K and Arnold, Kathryn B and Ganz, Patricia A and Santella, Regina M and Albanes, Demetrius and Taylor, Philip R and Probstfield, Jeffrey L and Jagpal, T. J and Crowley, John J and Meyskens, Frank L and Baker, Laurence H and Coltman, Charles A
JAMA, ISSN 0098-7484, 01/2009, Volume 301, Issue 1, pp. 39 - 51
CONTEXT Secondary analyses of 2 randomized controlled trials and supportive epidemiologic and preclinical data indicated the potential of selenium and vitamin... 
BREAST-CANCER | SUPPLEMENTATION | MORTALITY | MEDICINE, GENERAL & INTERNAL | BETA-CAROTENE | NUTRITIONAL PREVENTION | CARDIOVASCULAR-DISEASE | ALPHA-TOCOPHEROL | RANDOMIZED CONTROLLED-TRIAL | CELL-LINES | CARCINOMA | Double-Blind Method | Humans | Middle Aged | Male | Neoplasms - prevention & control | Treatment Outcome | Prostatic Neoplasms - epidemiology | Selenomethionine - therapeutic use | Selenium - therapeutic use | alpha-Tocopherol - therapeutic use | Antioxidants - therapeutic use | Vitamin E - therapeutic use | Aged | Prostatic Neoplasms - prevention & control | Dietary Supplements | Neoplasms - epidemiology | Disease prevention | Clinical trials | Selenium | Vitamin E | Prostate cancer | Risk factors | Index Medicus | Abridged Index Medicus
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10. Full Text Glucose variability in a 26-week randomized comparison of mealtime treatment with rapid-acting insulin versus glp-1 agonist in participants with type 2 diabetes at high cardiovascular risk
by Probstfield, Jeffrey L and Hirsch, Irl B and Davis, Barry R and Ahmann, Andrew and Bergenstal, Richard and Gilbert, Matthew and Kingry, Connie and Khakpour, Dorrine and Lai, Dejian and Pressel, Sarah L and Branch, Kelley R and Riddle, Matthew and O'Brien, Kevin D and FLAT-SUGAR Trial Investigators
Diabetes Care, ISSN 0149-5992, 06/2016, Volume 39, Issue 6, pp. 973 - 981
OBJECTIVEA1C is associated with diabetes complications but does not reflect glycemic variability (GV), which may worsen outcomes by inducing inflammation,... 
TRIAL | TWICE | METFORMIN | BASAL INSULIN | EXENATIDE | ENDOCRINOLOGY & METABOLISM | OPEN-LABEL | COMPLICATIONS | RECEPTOR AGONIST | Cardiovascular Diseases | Body Weight | Metformin - therapeutic use | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Male | Diabetes Mellitus, Type 2 - metabolism | Exenatide | Adult | Female | Drug Therapy, Combination | Hypoglycemia - chemically induced | Meals | Arrhythmias, Cardiac - epidemiology | Hypoglycemic Agents - therapeutic use | Serum Amyloid A Protein - metabolism | Risk Factors | Venoms - therapeutic use | Aged | Alanine Transaminase - metabolism | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Peptides - therapeutic use | Insulin, Short-Acting - therapeutic use | Type 2 diabetes | Care and treatment | Analysis | Dosage and administration | Glycemic index | Cardiovascular diseases | Insulin | Risk factors
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11. Full Text Prevention of Stroke by Antihypertensive Drug Treatment in Older Persons With Isolated Systolic Hypertension: Final Results of the Systolic Hypertension in the Elderly Program (SHEP)
by Probstfield, Jeffrey L
JAMA, ISSN 0098-7484, 06/1991, Volume 265, Issue 24, pp. 3255 - 3264
Objective.—To assess the ability of antihypertensive drug treatment to reduce the risk of nonfatal and fatal (total) stroke in isolated systolic... 
MORTALITY | TRIAL | POPULATION | MEDICINE, GENERAL & INTERNAL | OSLO | RISK | CARE | Hypertension | Stroke (Disease) | Prevention | Evaluation | Chlorthalidone | Demographic aspects | Antihypertensive drugs
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12. Full Text Effects of Intensive Blood-Pressure Control in Type 2 Diabetes Mellitus
by Cushman, William C and Evans, Gregory W and Byington, Robert P and Goff Jr, David C and Grimm Jr, Richard H and Cutler, Jeffrey A and Simons-Morton, Denise G and Basile, Jan N and Corson, Marshall A and Probstfield, Jeffrey L and Katz, Lois and Peterson, Kevin A and Friedewald, William T and Buse, John B and Bigger, J. Thomas and