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Cell, ISSN 0092-8674, 01/2013, Volume 152, Issue 3, pp. 532 - 542
G-protein-coupled receptors (GPCRs) can modulate diverse signaling pathways, often in a ligand-specific manner. The full range of functionally relevant... 
Biophysics and Computational biology | Biological sciences | Pharmacology
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1 - 13
... & R. Scott Prosser1,2 Cations play key roles in regulating G-protein-coupled receptors (GPCRs), although their mechanisms are poorly understood. Here, 19F NMR... 
Adenosine | Membranes | G protein-coupled receptors | Nuclear magnetic resonance--NMR | Calcium | Molecular dynamics | Cell membranes | Rigidity | Proteins | Receptors | Allosteric properties | Divalent cations | Affinity | Cations | Magnesium | Calcium ions | BASIC BIOLOGICAL SCIENCES | Biological Science
Journal Article
Biophysical Journal, ISSN 0006-3495, 07/2014, Volume 107, Issue 2, pp. 287 - 288
Journal Article
Journal Article
Nature, ISSN 0028-0836, 01/2010, Volume 463, Issue 7277, pp. 108 - 112
Journal Article
Journal of Biomolecular NMR, ISSN 0925-2738, 5/2015, Volume 62, Issue 1, pp. 97 - 103
... in 19 F NMR studies of proteins Libin Ye 1 • Sacha Thierry Larda 1 • Yi Feng Frank Li 1 • Aashish Manglik 2 • R. Scott Prosser 1,3 Received: 18 November 2014... 
Biochemistry, general | Spectroscopy/Spectrometry | BTFMA | Chemical tagging | BTFA | 19 F NMR | Chemical shift dispersion | TFET | Biophysics and Biological Physics | Physics | F NMR | Models, Molecular | Solvents | Proteins - chemistry | Nuclear Magnetic Resonance, Biomolecular - methods | Sensitivity and Specificity | 19F NMR
Journal Article
Cell, ISSN 0092-8674, 05/2015, Volume 161, Issue 5, pp. 1101 - 1111
G-protein-coupled receptors (GPCRs) transduce signals from the extracellular environment to intracellular proteins. To gain structural insight into the... 
Journal Article
Progress in Nuclear Magnetic Resonance Spectroscopy, ISSN 0079-6565, 2012, Volume 62, pp. 1 - 33
Highlights: F molecular tags and labeling protocols for F NMR studies of proteins are reviewed and contrasted. F NMR biosynthetic labeling strategies are... 
Biosynthetic labeling | Fluorinated tags | Protein dynamics | Protein conformation | Amino Acid Sequence | Fluorine - metabolism | Animals | Magnetic Resonance Spectroscopy - methods | Proteins - metabolism | Staining and Labeling | Molecular Sequence Data | Proteins - chemistry
Journal Article
Journal Article
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 01/2020, Volume 16, Issue 1, pp. 5 - 6
... and ligand response in GPCRs. R. Scott Prosser In eukaryotes, signal transduction across cell membranes in response to external input is often governed by a diverse... 
PROTEIN-COUPLED RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | Signal Transduction | Receptors, G-Protein-Coupled | Amino acid sequence | First principles | Directed evolution | Protein structure
Journal Article
Biophysical Journal, ISSN 0006-3495, 2002, Volume 82, Issue 5, pp. 2487 - 2498
The structural phase behavior of phospholipid mixtures consisting of short-chain (dihexanoyl phosphatidylcholine) and long-chain lipids (dimyristoyl... 
HIGH-RESOLUTION NMR | DIMYRISTOYLPHOSPHATIDYLCHOLINE | BIOPHYSICS | SOLID-STATE NMR | PHASE-BEHAVIOR | X-RAY-DIFFRACTION | DIPOLAR COUPLINGS | BILAYERED MIXED MICELLES | MEMBRANE-PROTEINS | BICELLES | SCATTERING | Rare earth metals | Sects | Phospholipids | Atoms & subatomic particles | Ions | Lipids
Journal Article