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index medicus (5) 5
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1. Full Text Evaluation of Serum Levels of Osteopontin and IgG Anti-Osteopontin Autoantibodies As Potential Biomarkers of Immune Activation in Patients with Allergic Diseases
by Villa, Elisa, Dr and Minisini, Rosalba, Dr and Rötzschke, Olaf, Dr and Puan, Kia Joo, Dr and San Luis, Boris Buenbrazo, Dr and Andiappan, Anand, Dr and Clemente, Nausicaa, Dr and Gigliotti, Luca, Dr and Boggio, Elena, Dr and Chiocchetti, Annalisa, Dr and Dianzani, Umberto, Prof and Pirisi, Mario, Prof
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 137, Issue 2, pp. AB394 - AB394
  Rationale Osteopontin (OPN) is a pleomorphic cytokine known to influence a wide range of immune cells; high OPN and IgG anti-OPN autoantibodies (AutoAbs)... 
Allergy and Immunology | Autoimmunity | Allergy | Care and treatment | Autoantibodies | Analysis | Immunoglobulin G | Allergic reaction | Biomarkers | Autoimmune diseases | Food allergies
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2. Full Text Establishing Criteria for Human Mesenchymal Stem Cell Potency
by Samsonraj, Rebekah M and Rai, Bina and Sathiyanathan, Padmapriya and Puan, Kia Joo and Rötzschke, Olaf and Hui, James H and Raghunath, Michael and Stanton, Lawrence W and Nurcombe, Victor and Cool, Simon M
STEM CELLS, ISSN 1066-5099, 06/2015, Volume 33, Issue 6, pp. 1878 - 1891
This study sought to identify critical determinants of mesenchymal stem cell (MSC) potency using in vitro and in vivo attributes of cells isolated from the... 
Growth capacity | PDGFR‐α | Potency | STRO‐1 | Quality | Mesenchymal stem/stromal cells | STRO-1 | PDGFR-α | PDGFR-alpha | OSTEOGENIC DIFFERENTIATION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | IN-VITRO | ONCOLOGY | stromal cells | HUMAN BONE-MARROW | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IMMUNOSUPPRESSION | MULTIPOTENTIALITY | CLINICAL-TRIALS | Mesenchymal stem | HEPARAN-SULFATE | GROWTH-FACTOR | HEMATOLOGY | EXPRESSION | Mesenchymal Stromal Cells - cytology | Animals | Cytokines - metabolism | Bone Marrow Cells - cytology | Humans | Cell Proliferation - physiology | Cells, Cultured | Mice | Wound Healing - physiology | Cell Differentiation - physiology | Platelet-derived growth factor | RNA | Chromosomes | Analysis | Stem cells | Inflation | Translational and Clinical Research
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3. Full Text Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation
by Kumar, D and Lee, B and Puan, KJ and Lee, W and San Luis, B and Yusof, N and Andiappan, AK and Del Rosario, R and Poschmann, J and Kumar, P and DeLibero, G and Singhal, A and Prabhakar, S and Yun, WD and Poidinger, M and Rotzschke, O
SCIENTIFIC REPORTS, ISSN 2045-2322, 10/2019, Volume 9, Issue 1, pp. 1 - 16
Resistin is a key cytokine associated with metabolic and inflammatory diseases. Especially in East Asian populations, the expression levels are strongly... 
PLASMA RESISTIN | POLYMORPHISMS | DNA METHYLATION | GENOTYPE | MULTIDISCIPLINARY SCIENCES | SERUM RESISTIN | AT-420 | GENE-EXPRESSION | KAPPA-B | ASSOCIATION | CORONARY-ARTERY-DISEASE | Haplotypes | NF-κB protein | Advanced glycosylation end products | Genetic control | S100b protein | Single-nucleotide polymorphism | Metabolism | Inflammatory diseases | Monocytes | Alleles | DNA methylation | Plasma levels | Acetylation | Interleukin 8 | CpG islands | Life Sciences
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4. Full Text Systematic characterization of basophil anergy
by Puan, Kia Joo and Andiappan, Anand Kumar and Lee, Bernett and Kumar, Dilip and Lai, Tuck Siong and Yeo, Giminna and Bercin, Derya and Starke, Mireille and Haase, Doreen and Lum, Josephine and Chew, Fook Tim and Connolly, John and Wong, Siew Cheng and Zolezzi, Francesca and Poidinger, Michael and Wang, De Yun and Rötzschke, Olaf
Allergy, ISSN 0105-4538, 03/2017, Volume 72, Issue 3, pp. 373 - 384
Background Cohort studies indicated that in certain individuals the basophils do not respond toward allergens due to a desensitization of their Fc epsilon... 
HDM | allergic rhinitis | basophil | anergy | TYROSINE KINASE | MAST-CELLS | MECHANISMS | IMMUNOLOGY | SYK EXPRESSION | EPSILON | B-CELLS | RESPONSES | AFFINITY IGE RECEPTOR | ALLERGY | SENSITIZATION | IN-VIVO | Rhinitis, Allergic - immunology | Humans | Hypersensitivity - immunology | Gene Expression Profiling | Rhinitis, Allergic - metabolism | Immunoglobulin E - blood | Immunoglobulin E - immunology | Allergens - immunology | Antibody Specificity - immunology | Hypersensitivity - metabolism | Syk Kinase - genetics | Basophils - immunology | Hypersensitivity - diagnosis | Hypersensitivity, Immediate - immunology | Hypersensitivity - genetics | Cross-Sectional Studies | Gene Expression Regulation | Immunophenotyping | Syk Kinase - metabolism | Animals | Hypersensitivity, Immediate - metabolism | Clonal Anergy - genetics | Biomarkers | Clonal Anergy - immunology | Basophils - metabolism | Cluster Analysis | Cohort Studies | Immunoglobulin E | Allergens | Allergy | Allergic reaction | Analysis | Histamine | Nose | Allergies | Deactivation | Desensitization | Anergy | Rhinitis | Urban areas | Therapeutic applications | Hypersensitivity | House dust | Allergic diseases | Allergic reactions | Inactivation | Fc receptors | Correlation analysis | Allergic rhinitis | Syk protein | Diagnostic systems | Leukocytes (basophilic) | Dust control
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5. Full Text Immune modulation of inflammatory conditions: regulatory T cells for treatment of GvHD
by Haase, Doreen and Starke, Mireille and Puan, Kia Joo and Lai, Tuck Siong and Rotzschke, Olaf
Immunologic Research, ISSN 0257-277X, 9/2012, Volume 53, Issue 1, pp. 200 - 212
The immune system is a highly balanced network of different cell types. This balance is disturbed in the setting of organ or stem cell transplantation, which... 
T REM | Treg | Internal Medicine | Rapamycin | Adoptive cell therapy | Medicine/Public Health, general | Cell isolation | Allergology | CD49d | Immunology | Medicine & Public Health | CD39 | Clinical trial | TREM | PROMOTES EXPANSION | STEROID-RESISTANT | CORD BLOOD | PHASE-II | PLUS METHYLPREDNISOLONE | IMMUNOLOGY | VERSUS-HOST-DISEASE | T-REM | HEMATOPOIETIC STEM-CELLS | TRANSCRIPTION FACTOR FOXP3 | CHEMOKINE RECEPTORS | MARROW TRANSPLANTATION | Graft vs Host Disease - therapy | T-Lymphocyte Subsets - immunology | Immunotherapy, Adoptive - methods | Cell Proliferation | Immunomodulation | Humans | Clinical Trials as Topic | Inflammation - immunology | T-Lymphocyte Subsets - transplantation | Graft vs Host Disease - immunology | T-Lymphocytes, Regulatory - immunology | Stem Cell Transplantation | Cell Differentiation - immunology | Inflammation - therapy | Animals | Immunologic Memory | Mice | T-Lymphocytes, Regulatory - transplantation | Disease Models, Animal | Transplants & implants | Cellular biology | Lymphocytes | Clinical trials | Pharmacology | Clinical outcomes | Immune system | Graft-versus-host reaction | Animal models | Immunological memory | Memory cells | Translation | CD49d antigen | CD8 antigen | Immunoregulation | Helper cells | Effector cells | Inflammation | Lymphocytes T | CCR6 protein | Chemokine receptors | CD4 antigen | Graft rejection | Side effects
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6. Full Text A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus
by Kumar, Dilip and Puan, Kia Joo and Andiappan, Anand Kumar and Lee, Bernett and Westerlaken, Geertje H.A and Haase, Doreen and Melchiotti, Rossella and Li, Zhuang and Yusof, Nurhashikin and Lum, Josephine and Koh, Geraldine and Foo, Shihui and Yeong, Joe and Alves, Alexessander Da Silva Couto and Pekkanen, Juha and Sun, Liang Dan and Irwanto, Astrid and Fairfax, Benjamin P and Naranbhai, Vivek and Common, John E.A and Tang, Mark B Y and Chuang, Chin Keh and Jarvelin, Marjo-Riitta and Knight, Julian C and Zhang, Xuejun and Chew, Fook Tim and Prabhakar, Shyam and Jianjun, Liu and Wang, De Yun and Zolezzi, Francesca and Poidinger, Michael and Lane, E. Birgitte and Meyaard, Linde and Rötzschke, Olaf
Genome Medicine, ISSN 1756-994X, 02/2017, Volume 9, Issue 1, pp. 18 - 16
Background: Expression quantitative trait loci (eQTL) databases represent a valuable resource to link disease-associated SNPs to specific candidate genes whose... 
Monocytes | Signal inhibitory receptor on leukocytes-1 (SIRL-1) | Molecular Biology | Atopic dermatitis | Genetics(clinical) | Neutrophils | Reactive oxygen species (ROS) | VSTM1 | Genetics | Molecular Medicine | Expression quantitative trait loci (eQTL) | Journal Article | GWAS | DNA METHYLATION | SIGNAL INHIBITORY RECEPTOR | CHINESE | PU.1 | ROLES | GENETICS & HEREDITY | CPG ISLANDS | EXPRESSION | LEUKOCYTES-1 | Promoter Regions, Genetic | Dermatitis, Atopic - genetics | Humans | Asian Continental Ancestry Group - genetics | Gene Expression Regulation | Male | Monocytes - metabolism | Young Adult | DNA Methylation | Female | Polymorphism, Single Nucleotide | Receptors, Immunologic - genetics | Dermatitis, Atopic - metabolism | Genetic aspects | Research | Single nucleotide polymorphisms | Methylation | Gene expression
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7. Full Text 806 POST TRANSRECTAL PROSTATE BIOPSY SEPSIS: A UNIQUE MODEL TO STUDY THE SYSTEMIC INFLAMMATORY RESPONSE SYNDROME
by Chong, Tsung Wen and Puan, Kia Joo and Wong, Siew Cheng
Journal of Urology, The, ISSN 0022-5347, 2010, Volume 183, Issue 4, pp. e315 - e315
Urology
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8. Full Text Preferential recognition of a microbial metabolite by human V 2V 2 T cells
by Puan, K.-J and Jin, C and Wang, H and Sarikonda, G and Raker, A. M and Lee, H. K and Samuelson, M. I and Marker-Hermann, E and Pasa-Tolic, L and Nieves, E and Giner, J.-L and Kuzuyama, T and Morita, C. T
International Immunology, ISSN 0953-8178, 03/2007, Volume 19, Issue 5, pp. 657 - 673
  Human Vγ2Vδ2 T cells are stimulated by prenyl pyrophosphates, such as isopentenyl pyrophosphate (IPP), and play important roles in mediating immunity against... 
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