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PLoS Genetics, ISSN 1553-7390, 05/2012, Volume 8, Issue 5, pp. e1002723 - e1002723
The epithelial-mesenchymal transition (EMT) is an embryonic transdifferentiation process consisting of conversion of polarized epithelial cells to motile... 
MIDDLE-T | TO-MESENCHYMAL TRANSITION | GENE | GROWTH | GENETICS & HEREDITY | PROTEIN PHOSPHATASE 2A | IDENTIFICATION | EXPRESSION | CANCER STEM-CELLS | TWIST | SNAIL | Epithelial Cells - metabolism | Homeodomain Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | Epithelial-Mesenchymal Transition - genetics | Mammary Glands, Human - metabolism | Breast Neoplasms - metabolism | Claudins - metabolism | Cell Transformation, Neoplastic - genetics | Female | Telomerase - metabolism | Cell Differentiation | Epithelial Cells - cytology | Cell Line | Claudins - genetics | Mammary Glands, Human - cytology | Protein Phosphatase 2 - antagonists & inhibitors | Retinoblastoma Protein - metabolism | Tumor Suppressor Protein p53 - metabolism | Mice, Transgenic | Transcription Factors - genetics | Cell Transformation, Neoplastic - metabolism | Homeodomain Proteins - genetics | Mammary Glands, Animal - cytology | Transcription Factors - metabolism | Animals | Breast Neoplasms - genetics | Mammary Glands, Animal - metabolism | Protein Phosphatase 2 - metabolism | Twist-Related Protein 1 - genetics | Mice | Genes, ras | Twist-Related Protein 1 - metabolism | Zinc Finger E-box-Binding Homeobox 1 | Transcription factors | Physiological aspects | Development and progression | Breast cancer | Genetic aspects | Research | Cell differentiation | Risk factors | Proteins | Rodents | Colonies & territories | Gene expression | Experiments | Tumors | Apoptosis | Index Medicus | Life Sciences | Cancer
Journal Article
Journal Article
by Granzotto, Adeline, BSc and Benadjaoud, Mohamed Amine, PhD and Vogin, Guillaume, MD, PhD and Devic, Clément, MSc and Ferlazzo, Mélanie L., MSc and Bodgi, Larry, PhD and Pereira, Sandrine, PhD and Sonzogni, Laurène, BSc and Forcheron, Fabien, PhD and Viau, Muriel, PhD and Etaix, Aurélie, PharmaD and Malek, Karim, MD, PhD and Mengue-Bindjeme, Laurence, MD, MSc and Escoffier, Clémence, MSc and Rouvet, Isabelle, PharmD, PhD and Zabot, Marie-Thérèse, PhD and Joubert, Aurélie, PhD and Vincent, Anne, PhD and Venezia, Nicole Dalla, PhD and Bourguignon, Michel, MD, PhD and Canat, Edme-Philippe, MD and d'Hombres, Anne, MD and Thébaud, Estelle, MD and Orbach, Daniel, MD and Stoppa-Lyonnet, Dominique, MD, PhD and Radji, Abderraouf, MD and Doré, Eric, MD and Pointreau, Yoann, MD and Bourgier, Céline, MD, PhD and Leblond, Pierre, MD, PhD and Defachelles, Anne-Sophie, MD and Lervat, Cyril, MD and Guey, Stéphanie, MD and Feuvret, Loic, MD and Gilsoul, Françoise, MD and Berger, Claire, MD and Moncharmont, Coralie, MD and de Laroche, Guy, MD and Moreau-Claeys, Marie-Virginie, MD and Chavaudra, Nicole, PhD and Combemale, Patrick, MD and Biston, Marie-Claude, PhD and Malet, Claude, PhD and Martel-Lafay, Isabelle, MD and Laude, Cécile, MD and Hau-Desbat, Ngoc-Hanh, MD and Ziouéche, Amira, MD and Tanguy, Ronan, MD and Sunyach, Marie-Pierre, MD and Racadot, Séverine, MD and Pommier, Pascal, MD, PhD and Claude, Line, MD and Baleydier, Frédéric, MD, PhD and Fleury, Bertrand, MD and de Crevoisier, Renaud, MD, PhD and Simon, Jean-Marc, MD, PhD and Verrelle, Pierre, MD, PhD and Peiffert, Didier, MD, PhD and Belkacemi, Yazid, MD, PhD and Bourhis, Jean, MD, PhD and Lartigau, Eric, MD, PhD and Carrie, Christian, MD and De Vathaire, Florent, PhD and Eschwege, François, MD, PhD and Puisieux, Alain, PharmD, PhD and Lagrange, Jean-Léon, MD, PhD and Balosso, Jacques, MD, PhD and Foray, Nicolas, PhD and COPERNIC Project Investigators and COPERNIC project investigators
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2016, Volume 94, Issue 3, pp. 450 - 460
Journal Article
Nature, ISSN 0028-0836, 10/2008, Volume 455, Issue 7215, pp. 967 - 970
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2009, Volume 10, Issue 7, pp. 778 - 785
Studies have suggested involvement of interleukin 17 (IL-17) in autoimmune diseases, although its effect on B cell biology has not been clearly established.... 
SURVIVAL | RECEPTOR STIMULATION | TOLERANCE CHECKPOINTS | INDUCED APOPTOSIS | GENE-EXPRESSION | LYMPHOCYTE STIMULATOR | IMMUNOLOGY | NF-KAPPA-B | UP-REGULATION | T-HELPER-CELLS | CUTTING EDGE | Apoptosis - drug effects | Minor Histocompatibility Antigens | Humans | Immunoblotting | Male | NF-kappa B - metabolism | Lupus Erythematosus, Systemic - blood | Interleukin-17 - pharmacology | Dose-Response Relationship, Drug | Immunoglobulins - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Time Factors | Female | Nuclear Proteins - genetics | B-Lymphocytes - metabolism | Repressor Proteins - metabolism | Interleukin-17 - blood | Cell Survival - drug effects | B-Lymphocytes - cytology | Cells, Cultured | Interleukin-17 - genetics | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Drug Synergism | B-Lymphocytes - drug effects | Cell Differentiation - drug effects | Twist-Related Protein 1 - genetics | Cell Line, Tumor | Antigens, CD19 - metabolism | B-Cell Activating Factor - pharmacology | Cell Proliferation - drug effects | Twist-Related Protein 1 - metabolism | Lupus Erythematosus, Systemic - pathology | Proto-Oncogene Proteins c-bcl-2 - genetics | Systemic lupus erythematosus | Interleukins | Physiological aspects | Genetic aspects | B cells | Research | DNA binding proteins | Health aspects | Risk factors | Index Medicus | Life Sciences | Other
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 2/2012, Volume 132, Issue 1, pp. 29 - 39
Understanding how cancer genes are mutated in individual tumors is an important issue with potential clinical and therapeutic impact. This is especially... 
Oncology | PI3K pathway | Breast cancer | Medicine & Public Health | Mutation screening | TP53 mutation | PTEN LOSS | PIK3CA MUTATIONS | COLORECTAL CANCERS | ANGIOGENESIS | EXPRESSION PROFILES | CONTINGENCY-TABLES | ONCOLOGY | CARCINOMAS | TUMORIGENESIS | CORRELATE | PTEN/MMAC1 | Carcinoma, Ductal, Breast - genetics | Receptors, Steroid - metabolism | Humans | Middle Aged | Carcinoma, Ductal, Breast - mortality | Carcinoma, Lobular - mortality | Proto-Oncogene Proteins c-akt - genetics | Tumor Suppressor Protein p53 - genetics | Breast Neoplasms - metabolism | Carcinoma, Lobular - genetics | DNA Mutational Analysis | Adult | Female | Cadherins - genetics | Carcinoma, Ductal, Breast - metabolism | PTEN Phosphohydrolase - genetics | Genetic Association Studies | Kaplan-Meier Estimate | Signal Transduction - genetics | Phosphatidylinositol 3-Kinases - genetics | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Breast Neoplasms - mortality | Aged | Carcinoma, Lobular - metabolism | Criminal investigation | Gene mutations | Genetic aspects | Chemical properties | Diagnosis | Tumor proteins | Health aspects | Cancer | Index Medicus | Signal Transduction | Carcinoma, Lobular | Breast Neoplasms | Phosphatidylinositol 3-Kinases | Proto-Oncogene Proteins c-akt | Life Sciences | Receptors, Steroid | Tumor Suppressor Protein p53 | PTEN Phosphohydrolase | Cadherins | Carcinoma, Ductal, Breast
Journal Article
Cancer Cell, ISSN 1535-6108, 07/2008, Volume 14, Issue 1, pp. 79 - 89
Twist1 and Twist2 are major regulators of embryogenesis. Twist1 has been shown to favor the metastatic dissemination of cancer cells through its ability to... 
CELLBIO | HUMDISEASE | SIGNALING | BREAST-CANCER | TRANSFORMATION | DORSOVENTRAL PATTERN | ONCOGENIC RAS | ONCOLOGY | IN-VIVO | ZYGOTIC GENE | SUPPRESSION | EXPRESSION | TUMORIGENESIS | CELL IMMORTALIZATION | Neoplasms - metabolism | Up-Regulation | Fibroblasts - enzymology | Epithelial Cells - metabolism | Humans | Gene Expression Regulation, Neoplastic | ras Proteins - metabolism | Transplantation, Heterologous | Cell Transdifferentiation - genetics | Mammary Glands, Human - metabolism | Transfection | Neoplasms - genetics | RNA Interference | Cell Transformation, Neoplastic - genetics | Mice, Inbred DBA | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Fibroblasts - metabolism | Cell Line | Cellular Senescence - genetics | Neoplasm Invasiveness | Mice, Inbred C57BL | Retinoblastoma Protein - metabolism | Tumor Suppressor Protein p53 - metabolism | Neoplasms - enzymology | Repressor Proteins - genetics | Epithelial Cells - pathology | Mice, Transgenic | Nuclear Proteins - metabolism | Fibroblasts - pathology | Cell Transformation, Neoplastic - metabolism | Animals | Mice, Nude | Dogs | Epithelial Cells - enzymology | Twist-Related Protein 1 - genetics | Mice | Enzyme Activation | Cell Transformation, Neoplastic - pathology | Neoplasms - pathology | Twist-Related Protein 1 - metabolism | Tumor proteins | Stem cells | Tumors | Index Medicus
Journal Article