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1. Full Text Objectives of iron chelation therapy in myelodysplastic syndromes: More than meets the eye?
by Pullarkat, Vinod
Blood, ISSN 0006-4971, 12/2009, Volume 114, Issue 26, pp. 5251 - 5255
The role of iron chelation therapy in myelodysplastic syndrome (MDS) remains controversial. Averting cardiac dysfunction in low-grade MDS patients who have... 
SERUM FERRITIN | OVERLOAD | TRANSFERRIN-BOUND IRON | RISK-FACTOR | LABILE PLASMA IRON | MYOCARDIAL IRON | STEM-CELL TRANSPLANTATION | HEMATOLOGY | ASSOCIATION | BINDING | MUCORMYCOSIS | Iron Overload - etiology | Iron Chelating Agents - therapeutic use | Animals | Iron Overload - prevention & control | Humans | Chelation Therapy | Clinical Trials as Topic | Iron | Myelodysplastic Syndromes - complications | Myelodysplastic Syndromes - drug therapy
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2. Full Text Improving erythropoiesis: a compelling case for iron chelation in myelofibrosis
by Pullarkat, Vinod
European Journal of Haematology, ISSN 0902-4441, 06/2016, Volume 96, Issue 6, pp. 549 - 550
Iron Overload - etiology | Iron Chelating Agents - therapeutic use | Erythrocyte Transfusion - adverse effects | Iron Chelating Agents - pharmacology | Iron Overload - drug therapy | Primary Myelofibrosis - complications | Humans | Primary Myelofibrosis - physiopathology | Erythropoiesis - drug effects | Treatment Outcome | Primary Myelofibrosis - therapy
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3. Full Text Response to single agent dasatinib post allogeneic transplant in B-cell acute lymphoblastic leukemia with NUP214-ABL1
by Aldoss, Ibrahim and Pullarkat, Vinod
Leukemia & Lymphoma, ISSN 1042-8194, 09/2019, Volume 60, Issue 11, pp. 2832 - 2834
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4. Full Text Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial
by Kuter, David J, Prof and Bussel, James B, MD and Lyons, Roger M, MD and Pullarkat, Vinod, MD and Gernsheimer, Terry B, MD and Senecal, Francis M, MD and Aledort, Louis M, MD and George, James N, MD and Kessler, Craig M, MD and Sanz, Miguel A, MD and Liebman, Howard A, MD and Slovick, Frank T, MD and de Wolf, J Th M, MD and Bourgeois, Emmanuelle, MD and Guthrie, Troy H, MD and Newland, Adrian, MA and Wasser, Jeffrey S, MD and Hamburg, Solomon I, MD and Grande, Carlos, MD and Lefrère, François, MD and Lichtin, Alan Eli, MD and Tarantino, Michael D, MD and Terebelo, Howard R, DO and Viallard, Jean-François, MD and Cuevas, Francis J, MD and Go, Ronald S, MD and Henry, David H, MD and Redner, Robert L, MD and Rice, Lawrence, MD and Schipperus, Martin R, MD and Guo, D Matthew, PhD and Nichol, Janet L, MS
Lancet, The, ISSN 0140-6736, 02/2008, Volume 371, Issue 9610, pp. 395 - 403
Summary Background Chronic immune thrombocytopenic purpura (ITP) is characterised by accelerated platelet destruction and decreased platelet production.... 
Internal Medicine | AUTOANTIBODIES | ADULT PATIENTS | IN-VITRO | AMG-531 | MEGAKARYOCYTES | CHRONIC ITP | PLATELET DESTRUCTION | SPLENECTOMY | UMCG Approved | THROMBOPOIETIN LEVELS | TGF-BETA-1 | MEDICINE, GENERAL & INTERNAL | Double-Blind Method | Drug Administration Schedule | Humans | Middle Aged | Male | Treatment Outcome | Recombinant Fusion Proteins | Thrombopoietin | Receptors, Fc - therapeutic use | Carrier Proteins - adverse effects | Splenectomy | Platelet Count | Receptors, Fc - administration & dosage | Carrier Proteins - administration & dosage | Purpura, Thrombotic Thrombocytopenic - drug therapy | Purpura, Thrombotic Thrombocytopenic - immunology | Adult | Female | Aged | Carrier Proteins - therapeutic use | Purpura, Thrombotic Thrombocytopenic - blood | Chronic Disease - drug therapy | Thrombocytopenic purpura | Drug therapy | Research | Clinical trials | Blood diseases | Medical treatment | Chronic illnesses
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5. Full Text Indications for allogeneic hematopoietic cell transplantation for adults with Philadelphia-chromosome negative acute lymphoblastic leukemia in first complete remission: all about MRD?
by Aldoss, Ibrahim and Pullarkat, Vinod
Bone Marrow Transplantation, ISSN 0268-3369, 01/2019, Volume 54, Issue 1, pp. 3 - 5
THERAPY | ONCOLOGY | REGIMEN | IMMUNOLOGY | HEMATOLOGY | CHEMOTHERAPY | TRANSPLANTATION | Care and treatment | Patient outcomes | Development and progression | Genetic aspects | Transplantation | Acute lymphocytic leukemia | Health aspects | Hematopoietic stem cells | Methods | Philadelphia chromosome | Acute lymphatic leukemia | Leukemia | Remission | Adults | Lymphatic leukemia | Hemopoiesis
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6. Full Text Iron overload in patients undergoing hematopoietic stem cell transplantation
by Pullarkat, Vinod
Advances in Hematology, ISSN 1687-9104, 2010, Volume 2010, pp. 1 - 12
Recipients of hematopoietic stem cell transplantation (HSCT) frequently have iron overload resulting from chronic transfusion therapy for anemia. In some... 
Review
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7. Full Text Response to single agent dasatinib post allogeneic transplant in B-cell acute lymphoblastic leukemia with NUP214-ABL1
by Aldoss, Ibrahim and Pullarkat, Vinod
Leukemia & lymphoma, 04/2019, p. 1
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8. Full Text Treatment of the older adult with ALL: An urgent call to action
by Pullarkat, Vinod, MD MRCP
Leukemia Research, ISSN 0145-2126, 2016, Volume 41, pp. 3 - 4
Hematology, Oncology and Palliative Medicine | REGIMEN | ONCOLOGY | HEMATOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Female | Male | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Humans | Aged
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9. Full Text Iron Toxicity in Hematopoietic Stem Cell Transplantation: Strike while the Iron Is Labile
by Pullarkat, Vinod
Acta Haematologica, ISSN 0001-5792, 05/2014, Volume 131, Issue 4, pp. 220 - 221
Editorial Comment | OVERLOAD | SERUM | BOUND IRON | HEMATOLOGY | Iron Overload - etiology | Humans | Hematopoietic Stem Cell Transplantation - adverse effects | Female | Graft Survival | Male | Transplantation Conditioning - adverse effects | Iron - blood
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10. Full Text Hypomethylating agents in combination with venetoclax for acute myeloid leukemia: Update on clinical trial data and practical considerations for use
by Mei, Matthew and Aldoss, Ibrahim and Marcucci, Guido and Pullarkat, Vinod
American Journal of Hematology, ISSN 0361-8609, 03/2019, Volume 94, Issue 3, pp. 358 - 362
One of the most promising developments in therapy for acute myeloid leukemia (AML) in recent years has been the combination of hypomethylating agents (HMA,... 
HEMATOLOGY | Clinical trials | Drug approval | Usage
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11. Full Text Autoimmune myelofibrosis: an update on morphologic features in 29 cases and review of the literature
by Vergara-Lluri, Maria E., MD and Piatek, Caroline I., MD and Pullarkat, Vinod, MD and Siddiqi, Imran N., MD, PhD and O'Connell, Casey, MD and Feinstein, Donald I., MD and Brynes, Russell K., MD
Human Pathology, ISSN 0046-8177, 2014, Volume 45, Issue 11, pp. 2183 - 2191
Summary Autoimmune myelofibrosis (AIMF) is a distinct clinicopathological entity associated with diffuse bone marrow fibrosis and a benign clinical course.... 
Pathology | Autoimmune myelofibrosis | Morphologic criteria | Bone marrow fibrosis | Autoimmune disorders | Non-neoplastic fibrosis | IgG4 related disease | SYSTEMIC-LUPUS-ERYTHEMATOSUS | CONSENSUS | PANCYTOPENIA | PATHOLOGY | BONE-MARROW FIBROSIS | REVERSAL | Young Adult | Humans | Middle Aged | Adult | Female | Male | Aged | Primary Myelofibrosis - pathology | Autoimmune Diseases - pathology | Lupus | Hepatitis | Transplants & implants | Disease | Lymphocytes | Medical prognosis | Bone marrow | Autoimmune diseases | Metabolic disorders | Immune system | Tumors
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12. Phenotype and Function of Bone Marrow Infiltrating Lymphocytes in Chronic Myelogenous Leukemia
by Pullarkat, Vinod
2008, AD-a486 763.
The aims of this project are to determine the phenotype and antileukemic activity of activated bone marrow infiltrating leukemia (MIL) and compare them to... 
phenotype | leukemia | inhibitors | lymphocytes | t lymphocytes | therapy | patients | blood counts | bone marrow | phosphorus transferases | t-cell expansion | immunotherapy | cml(chronic myeloid leukemia) | chronic myeloid leukemia | tyrosine | mil(marrow-infiltrating lymphocytes)
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13. Full Text Phase II Study of Vorinostat for Treatment of Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma and Mantle Cell Lymphoma
by Mark Kirschbaum and Paul Frankel and Leslie Popplewell and Jasmine Zain and Maria Delioukina and Vinod Pullarkat and Deron Matsuoka and Bernadette Pulone and Arnold J. Rotter and Igor Espinoza-Delgado and Auayporn Nademanee and Stephen J. Forman and David Gandara and Edward Newman
Journal of Clinical Oncology, ISSN 0732-183X, 03/2011, Volume 29, Issue 9, pp. 1198 - 1203
Purpose We performed a phase II study of oral vorinostat, a histone and protein deacetylase inhibitor, to examine its efficacy and tolerability in patients... 
BENDAMUSTINE | HISTONE DEACETYLASE INHIBITOR | RESPONSE CRITERIA | ONCOLOGY | RITUXIMAB | FOLLOW-UP | LOW-GRADE | FOLLICULAR LYMPHOMA | LEUKEMIA CELLS | EXPRESSION | TRANSPLANTATION | Lymphoma, Follicular - drug therapy | Administration, Oral | Lymphoma, Follicular - pathology | Humans | Middle Aged | Lymphoma, Mantle-Cell - pathology | Salvage Therapy | Lymphoma, Mantle-Cell - drug therapy | Neoplasm Recurrence, Local - drug therapy | Male | Survival Rate | Treatment Outcome | Antineoplastic Agents - therapeutic use | Remission Induction | Neoplasm Recurrence, Local - pathology | Lymphoma, B-Cell, Marginal Zone - drug therapy | Adult | Female | Hydroxamic Acids - therapeutic use | Lymphoma, B-Cell, Marginal Zone - pathology | Aged | Drug Resistance, Neoplasm - drug effects | Index Medicus | Original Reports | Hema15
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14. Full Text Correlates of resistance and relapse during blinatumomab therapy for relapsed/refractory acute lymphoblastic leukemia
by Aldoss, Ibrahim and Song, Joo and Stiller, Tracey and Nguyen, Tina and Palmer, Joycelynne and O'Donnell, Margaret and Stein, Anthony S and Marcucci, Guido and Forman, Stephen and Pullarkat, Vinod
American Journal of Hematology, ISSN 0361-8609, 09/2017, Volume 92, Issue 9, pp. 858 - 865
We retrospectively analyzed 65 patients with refractory/relapsed (r/r) ALL who were treated with blinatumomab for predictors of leukemia response as well as... 
CYTOKINE-RELEASE SYNDROME | ANTIBODY CONSTRUCT | B-CELL | T-CELL-ACTIVATION | BITE | IBRUTINIB | LYSIS | HEMATOLOGY | Humans | Middle Aged | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Allografts | Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy | Antibodies, Bispecific - administration & dosage | Blast Crisis - mortality | Adult | Female | Retrospective Studies | Child | Bone Marrow Cells - pathology | Gene Expression Regulation, Leukemic - drug effects | Hematopoietic Stem Cell Transplantation | Survival Rate | Drug Resistance - drug effects | Blast Crisis - therapy | Down-Regulation - drug effects | Remission Induction | Disease-Free Survival | Blast Crisis - blood | Adolescent | Neoplasm Proteins - blood | Aged | Antigens, CD19 - blood | Bone Marrow Cells - metabolism | Bone marrow | Transplantation | Analysis | Hematopoietic stem cells | Index Medicus
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15. Full Text Adults with Philadelphia Chromosome–Like Acute Lymphoblastic Leukemia: Considerations for Allogeneic Hematopoietic Cell Transplantation in First Complete Remission
by Aldoss, Ibrahim and Kamal, Muhammad O and Forman, Stephen J and Pullarkat, Vinod
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 02/2019, Volume 25, Issue 2, pp. e41 - e45
Philadelphia chromosome–like (Ph-like) acute lymphoblastic leukemia (ALL) is a subset of high-risk B cell ALLs. A large proportion of Ph-like ALL cases carry... 
Allogeneic | ALL | Philadelphia chromosome–like | Hematopoietic cell transplantation | Acute lymphoblastic leukemia | HCT | Ph-like | Tyrosine | Chemotherapy | Analysis | Immunotherapy | Genetic research | Adults | Genetic aspects | Transplantation | Acute lymphocytic leukemia | Hematopoietic stem cells | Cancer
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16. Full Text Venetoclax and hypomethylating agents in TP53‐mutated acute myeloid leukaemia
by Aldoss, Ibrahim and Zhang, Jianying and Pillai, Raju and Shouse, Geoffrey and Sanchez, James F and Mei, Matthew and Nakamura, Ryotaro and Stein, Anthony S and Forman, Stephen J and Marcucci, Guido and Pullarkat, Vinod
British Journal of Haematology, ISSN 0007-1048, 10/2019, Volume 187, Issue 2, pp. e45 - e48
hypomethylating agents | decitabine | venetoclax | acute myeloid leukaemia | TP53 | Tumor proteins | Leukemia | p53 Protein
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17. Phenotype and Function of Bone Marrow Infiltrating Lymphocytes in Chronic Myelogenous Leukemia
by Pullarkat, Vinod
2007, AD-a471 557.
The aims of this project are to determine the phenotype and antileukemic activity of activated bone marrow infiltrating leukemia (MIL) and compare them to... 
phenotype | leukemia | inhibitors | t lymphocytes | lymphocytes | memory devices | therapy | patients | chronic myelogenous leukemia | blood counts | bone marrow | phosphorus transferases | t-cell expansion | immunotherapy | chronic myeloid leukemia | marrow-infiltrating lymphocytes | tyrosine
Government Document
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18. Full Text Prognostic and therapeutic implications of early treatment response assessment in acute myeloid leukemia
by Pullarkat, Vinod and Aldoss, Ibrahim
Critical Reviews in Oncology and Hematology, ISSN 1040-8428, 2015, Volume 95, Issue 1, pp. 38 - 45
Highlights • We discuss the role of early treatment response assessment by day 14 bone marrow biopsy in AML. • We discuss the lack of standardization of what... 
Hematology, Oncology and Palliative Medicine | Chemosensitivity | Early response | Reinduction | Acute myeloid leukemia | Day 14 bone marrow | SURVIVAL | PREDICTS | MULTICENTER | INDUCTION CHEMOTHERAPY | COMPLETE REMISSION | BLOOD BLAST CLEARANCE | BONE-MARROW ANGIOGENESIS | TRIAL | ONCOLOGY | CONSOLIDATION THERAPY | HEMATOLOGY | AML COOPERATIVE GROUP | Neoplasm, Residual - pathology | Leukemia, Myeloid, Acute - diagnosis | Prognosis | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Leukemia, Myeloid, Acute - pathology | Bone Marrow - pathology | Humans | Neoplasm, Residual - diagnosis | Induction Chemotherapy - methods | Neoplasm, Residual - drug therapy | Leukemia, Myeloid, Acute - drug therapy | Bone Marrow - drug effects | Health aspects | Blood | Medical examination
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19. Full Text Safety and efficacy of long-term treatment with romiplostim in thrombocytopenic patients with chronic ITP
by Bussel, James B and Kuter, David J and Pullarkat, Vinod and Lyons, Roger M and Guo, Matthew and Nichol, Janet L
Blood, ISSN 0006-4971, 03/2009, Volume 113, Issue 10, pp. 2161 - 2171
Chronic immune thrombocytopenic purpura (ITP) is characterized by low platelet counts and mucocutaneous bleeding. In previous studies romiplostim (AMG531), a... 
AUTOIMMUNE THROMBOCYTOPENIA | ADULT PATIENTS | INTRAVENOUS GAMMA-GLOBULIN | IN-VITRO | PURPURA | AMG-531 | BONE-MARROW | SPLENECTOMY | PLATELET PRODUCTION | HEMATOLOGY | THROMBOPOIETIN LEVELS | Humans | Middle Aged | Male | Recombinant Fusion Proteins | Thrombopoietin | Purpura, Thrombocytopenic, Idiopathic - drug therapy | Carrier Proteins - adverse effects | Platelet Count | Receptors, Fc - administration & dosage | Carrier Proteins - administration & dosage | Female | Blood Platelets - drug effects | Thrombopoiesis - drug effects
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20. Full Text Venetoclax combined with decitabine or azacitidine in treatment-naive, elderly patients with acute myeloid leukemia
by DiNardo, Courtney D and Pratz, Keith and Pullarkat, Vinod and Jonas, Brian A and Arellano, Martha and Becker, Pamela S and Frankfurt, Olga and Konopleva, Marina and Wei, Andrew H and Kantarjian, Hagop M and Xu, Tu and Hong, Wan-Jen and Chyla, Brenda and Potluri, Jalaja and Pollyea, Daniel A and Letai, Anthony
Blood, ISSN 0006-4971, 01/2019, Volume 133, Issue 1, pp. 7 - 17
Older patients with acute myeloid leukemia (AML) respond poorly to standard induction therapy. B-cell lymphoma 2 (BCL-2) overexpression is implicated in... 
CONVENTIONAL CARE REGIMENS | REPORTING STANDARDS | INTENSIVE CHEMOTHERAPY | OLDER PATIENTS | REVISED RECOMMENDATIONS | RISK MYELODYSPLASTIC SYNDROME | LOW-DOSE CYTARABINE | PROGNOSTIC RELEVANCE | HEMATOLOGY | INTERNATIONAL WORKING GROUP | THERAPEUTIC TRIALS | Decitabine - administration & dosage | Prognosis | Follow-Up Studies | Leukemia, Myeloid, Acute - pathology | Humans | Male | Survival Rate | Bridged Bicyclo Compounds, Heterocyclic - administration & dosage | Maximum Tolerated Dose | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Female | Aged | Sulfonamides - administration & dosage | Azacitidine - administration & dosage | Cohort Studies | Plenary Paper
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