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Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 5025 - 5025
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7653, pp. 175 - 180
Melanoma of the skin is a common cancer only in Europeans, whereas it arises in internal body surfaces (mucosal sites) and on the hands and feet (acral sites)... 
TERT PROMOTER MUTATIONS | UVEAL MELANOMA | SEQUENCE DATA | MULTIDISCIPLINARY SCIENCES | RECURRENT MUTATIONS | FREQUENT SOMATIC MUTATIONS | MALIGNANT-MELANOMA | GENERAL FRAMEWORK | CANCER GENOMES | ACTIVATING MUTATIONS | DRIVER MUTATIONS | Membrane Proteins - genetics | Humans | X-linked Nuclear Protein | Phosphoproteins - genetics | RNA Splicing Factors - genetics | Mutation - genetics | Genes, p16 | Genome, Human - genetics | Tumor Suppressor Protein p53 - genetics | Ultraviolet Rays - adverse effects | Telomerase - genetics | Signal Transduction - drug effects | GTP Phosphohydrolases - genetics | Melanoma - genetics | Proto-Oncogene Proteins B-raf - genetics | Mitogen-Activated Protein Kinases - genetics | Neurofibromatosis 1 - genetics | Melanoma - classification | Nuclear Proteins - genetics | DNA Helicases - genetics | Telomere - genetics | Genetic research | Genetic aspects | Genomes | Research | Melanoma | Pathogenesis | Copy number | Mucosa | p53 Protein | Radiation | Security | Epidemiology | Metastases | Scholarships & fellowships | Reproduction (copying) | Coding | Mismatch repair | Clusters | Eye (anatomy) | Deoxyribonucleic acid--DNA | Medical research | Breakpoints | Radiation effects | MAP kinase | Exposure | Sun | Amplification | Bridges | Pathology | Ultraviolet radiation | Mutagenesis | Computation | Skin | Mutation | Internet | Aberration | Biotechnology | Genes | DNA damage | Carcinogens | Infrastructure | Signatures | Health | U.V. radiation | Inversions | Foldback | Data processing | Energy policy | Readers | Deamination | Protein kinase | Cell lines | Gene mapping | Tumors | Cancer | Index Medicus | Biological Science | 60 APPLIED LIFE SCIENCES
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 5694
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2014, Volume 20, Issue 7, pp. 1965 - 1977
Journal Article
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2015, Volume 51, Issue 18, pp. 2792 - 2799
Abstract Background Acquired resistance to BRAF inhibitors (BRAFi) is a near-universal phenomenon caused by numerous genetic and non-genetic alterations. In... 
Hematology, Oncology and Palliative Medicine | Resistance | Vemurafenib | NRAS | Splice | Acquired | Dabrafenib | BRAF | MEK1 | MAPK | Meta-analysis | SURVIVAL | RAF INHIBITION | METASTATIC MELANOMA | THERAPY | ONCOLOGY | PATHWAY | COBIMETINIB | B-RAF | MUTATIONS | Skin Neoplasms - drug therapy | United States | Humans | Middle Aged | Melanoma - enzymology | Male | Antineoplastic Agents - therapeutic use | Skin Neoplasms - enzymology | Time Factors | DNA Mutational Analysis | Melanoma - genetics | Skin Neoplasms - mortality | Biomarkers, Tumor - metabolism | Female | Biomarkers, Tumor - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - metabolism | Skin Neoplasms - pathology | Genetic Predisposition to Disease | Europe | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Treatment Outcome | Melanoma - pathology | Disease Progression | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Disease-Free Survival | Drug Resistance, Neoplasm - genetics | Phenotype | Signal Transduction - drug effects | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Skin Neoplasms - genetics | Biomarkers, Tumor - genetics | Mutation | Australia | Melanoma - mortality | splice | vemurafenib | meta-analysis | resistance | amplification | spectrum | MEK2 | dabrafenib | acquired
Journal Article
BMC Genomics, ISSN 1471-2164, 11/2012, Volume 13, p. 677
HIV-associated dementia (HAD) is the most common dementia type in young adults less than 40 years of age. Although the neurotoxins, oxidative/metabolic stress... 
Messenger RNA | Physiological aspects | HIV patients | Nervous system | Genetic aspects | Cellular signal transduction | Degeneration | Research | Dementia
Journal Article
Molecular Oncology, ISSN 1574-7891, 05/2014, Volume 8, Issue 3, pp. 544 - 554
Acquired resistance to BRAF inhibitors often involves MAPK re-activation, yet the MEK inhibitor trametinib showed minimal clinical activity in melanoma... 
ERK inhibitors | Acquired resistance | BRAF inhibitors | MEK inhibitors | Melanoma | DABRAFENIB | CELLS | TRAMETINIB | ACQUIRED-RESISTANCE | OPEN-LABEL | PATHWAY INHIBITION | OVERCOME | AMPLIFICATION | BRAE inhibitors | ONCOLOGY | MUTATIONS | VEMURAFENIB | Melanoma - metabolism | TOR Serine-Threonine Kinases - metabolism | Apoptosis - drug effects | Humans | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Drug Resistance, Neoplasm | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | TOR Serine-Threonine Kinases - antagonists & inhibitors | Mitogen-Activated Protein Kinase Kinases - metabolism | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Signal Transduction - drug effects | Melanoma - drug therapy | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Tumor Cells, Cultured | Proto-Oncogene Proteins B-raf - metabolism | Mitogen-Activated Protein Kinases - metabolism | Medical colleges | Care and treatment | Analysis | Oncology, Experimental | Research | Cancer | TOR protein | Cell proliferation | Cell culture | Extracellular signal-regulated kinase | MAP kinase | Kinases | Drug resistance | Patients | 1-Phosphatidylinositol 3-kinase | Proteins | Cell death | Cell cycle | Mutation | Apoptosis
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2017, Volume 23, Issue 20, pp. 6054 - 6061
Journal Article
BMC Genomics, ISSN 1471-2164, 11/2012, Volume 13, Issue 1, pp. 677 - 677
Background: HIV-associated dementia (HAD) is the most common dementia type in young adults less than 40 years of age. Although the neurotoxins,... 
MicroRNA | HIV | Axon guidance | Microarray | HIV-associated dementia | Neurodegeneration | DISEASE BRAIN | PATTERNS | PREFRONTAL CORTEX | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MIRNA | GENETICS & HEREDITY | IMMUNODEFICIENCY-VIRUS TYPE-1 | GENE-EXPRESSION | INFECTION | TRANSCRIPTIONAL REGULATION | CEREBRAL-ISCHEMIA | UP-REGULATION | Frontal Lobe - virology | Frontal Lobe - metabolism | HIV - physiology | Oligonucleotide Array Sequence Analysis | Genomics | Humans | Middle Aged | Male | MicroRNAs - metabolism | Gene Expression Profiling | RNA, Messenger - metabolism | HIV Infections - pathology | AIDS Dementia Complex - pathology | Adult | HIV Infections - genetics | RNA, Messenger - genetics | Signal Transduction - genetics | AIDS Dementia Complex - diagnosis | Genome, Human - genetics | AIDS Dementia Complex - genetics | Axons - pathology | HIV Infections - complications | MicroRNAs - genetics | Early Diagnosis | Frontal Lobe - pathology | Brain | Nervous system diseases | Genes | HIV patients | Nervous system | HIV (Viruses) | Messenger RNA | Analysis | Cellular signal transduction | Degeneration | Health aspects | Biotechnology industry | Dementia | Medical research | Disease | Ontology | Pathogenesis | Colleges & universities | Schizophrenia | Infections | Genomes | Scholarships & fellowships | Brain research | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Genetic engineering | Regulation
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 11/2014, Volume 134, Issue 11, pp. 2795 - 2805
Journal Article