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Nature Chemical Biology, ISSN 1552-4450, 12/2013, Volume 9, Issue 12, pp. 840 - 848
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 04/2010, Volume 24, Issue 8, pp. 783 - 789
Journal Article
Cancer Cell, ISSN 1535-6108, 07/2013, Volume 24, Issue 1, pp. 45 - 58
Journal Article
Blood, ISSN 0006-4971, 01/2017, Volume 129, Issue 4, pp. 497 - 508
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2014, Volume 211, Issue 4, pp. 605 - 612
Despite extensive insights into the underlying genetics and biology of acute myeloid leukemia (AML), overall survival remains poor and new therapies are... 
TRANSFORMATION | MLL-AF9 | TARGET | AML | MEDICINE, RESEARCH & EXPERIMENTAL | STEM-CELLS | ACTIVATION | SCREEN | PHOSPHORYLATION | RAS | ALPHA | IMMUNOLOGY | 304 | Brief Definitive Report | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 209 - 209
Abstract Abstract 209 In order to identify novel approaches to the targeting of acute myeloid leukemia (AML), we performed a pooled in vivo shRNA screen on... 
Journal Article
Cancer cell, ISSN 1535-6108, 7/2013, Volume 24, Issue 1, pp. 45 - 58
We used an in vivo short hairpin RNA (shRNA) screening approach to identify genes that are essential for MLL-AF9 acute myeloid leukemia (AML). We found that... 
Journal Article
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 21, pp. 758 - 758
Abstract Abstract 758 Primary leukemia stem cells (LSCs) reside in an in vivo microenvironment that supports the growth and survival of malignant cells.... 
Journal Article
Cell, ISSN 1097-4172, 2016, Volume 165, Issue 2, p. 16
Leukemia stem cells (LSCs) have the capacity to self-renew and propagate disease upon serial transplantation in animal models, and elimination of this cell... 
Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Cell and Molecular Biology | Cell- och molekylärbiologi
Journal Article
01/2014, ISBN 9781321335255
Acute myeloid leukemia (AML) is a clonal neoplastic disorder organized as a cellular hierarchy, with the self-renewing leukemia stem cell (LSC) at the apex.... 
Oncology | Biochemistry | Physiology
Dissertation
01/2011, ISBN 1124729526
The proper formation and morphogenesis of dendrites is fundamental to the establishment of neural circuits in the brain. Following exit from the cell cycle and... 
Neurobiology | Molecular biology
Dissertation
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