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1. Full Text Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
by Gormley, A.M and Stefansson, Hreinn and Winsvold, Bendik and Palta, Priit and Esko, Tõnu and Pers, Tune and Farh, Kai-How and Cuenca-Leon, E and Muona, M and Furlotte, N.A and Kurth, Karl and Ingason, Anes and Mcmahon, George and Ligthart, Lannie and Terwindt, Gisela and Todt, Unda and Müller-Myhsok, Bertram and Ran, C and Gordon, S.G and Stam, Anine and Steinberg, Stacy and Göbel, Hartmut and Koiranen, Markku and Quaye, Lydia and Adams, H.H.H and Lehtimäki, Terho and Sarin, A.-P and Wedenoja, J and Hinds, David A and Buring, J.E and Schürks, Markus and Ridker, Paul and Hrafnsdottir, M.G and Ring, Susan and Hottenga, Jouke Jan and Penninx, Brenda and Färkkilä, Markus and Artto, Ville and Hämäläinen, Eija and Lucae, Susanne and Malik, Rainer and Heath, Anew C and Madden, Pamela and Martin, Nicholas and Montgomery, Grant and Kurki, M.I and Kals, Mart and Mägi, Reedik and Pärn, K and Huang, H and Byrnes, A.E and Franke, Lude and Huang, Jian and Stergiakouli, Evangelia and Lee, Phil and Sandor, C and Webber, C and Cader, Z and Müller-Myhsok, B and Schreiber, Stefan and Meitinger, Thomas and Hagen, Knut and Salomaa, Veikko and Heikkilä, Kauko and Loehrer, Elizabeth and Uitterlinden, Ané and Hofman, A and Duijn, Cornelia and Cherkas, Lynn and Pedersen, L.M and Stubhaug, A and Nielsen, C.S and Männikkö, M and Mihailov, Evelin and Milani, Lili and Esserlind, A.-L and Christensen, A.F and Hansen, T.F and Werge, Thomas and Kaprio, Jaakko and Aromaa, Arpo and Raitakari, Olli and Ikram, Arfan and Ikram, Kamran and Jarvelin, Marjo-Riitta and Metspalu, Anes and Kubisch, Christian and Strachan, David and Ferrari, Michel and Belin, A.C and Wessman, Maija and Maagdenberg, Arn and Zwart, John-Anker and Boomsma, Dorret and Smith, G.D and Stefansson, K and Eriksson, Nicholas and Daly, Mark and Neale, Benjamin and Olesen, Jes and ... and Int Headache Genetics Consortium and International Headache Genetics Consortium
Nature genetics, ISSN 1061-4036, 08/2016, Volume 48, Issue 8, pp. 856 - 866
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Migraine Disorders - genetics | Genetic Markers - genetics | Genomics | Humans | Genetic Loci - genetics | Polymorphism, Single Nucleotide - genetics | Vascular Diseases - genetics | Muscle, Smooth - metabolism | Case-Control Studies | Quantitative trait loci | Genome-wide association studies | Migraine | Genetic aspects | Gene expression | Identification and classification | Health aspects | Risk factors | Methods | Studies | Confidence intervals | Consortia | Headaches | Gene loci | Genomes | Meta-analysis | Index Medicus | Medicin och hälsovetenskap
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2. Full Text Genome-wide meta-analysis identifies new susceptibility loci for migraine
by Anttila, Verneri and Winsvold, Bendik S and Gormley, Padhraig and Kurth, Tobias and Bettella, Francesco and McMahon, George and Kallela, Mikko and Malik, Rainer and de Vries, Boukje and Terwindt, Gisela and Medland, Sarah E and Todt, Unda and McArdle, Wendy L and Quaye, Lydia and Koiranen, Markku and Ikram, M. Arfan and Lehtimaki, Terho and Stam, Anine H and Ligthart, Lannie and Wedenoja, Juho and Dunham, Ian and Neale, Benjamin M and Palta, Priit and Hamalainen, Eija and Schuerks, Markus and Rose, Lynda M and Buring, Julie E and Ridker, Paul M and Steinberg, Stacy and Stefansson, Hreinn and Jakobsson, Finnbogi and Lawlor, Debbie A and Evans, David M and Ring, Susan M and Farkkila, Markus and Artto, Ville and Kaunisto, Mari A and Freilinger, Tobias and Schoenen, Jean and Frants, Rune R and Pelzer, Nadine and Weller, Claudia M and Zielman, Ronald and Heath, Anew C and Madden, Pamela A. F and Montgomery, Grant W and Martin, Nicholas G and Borck, Guntram and Goebel, Hartmut and Heinze, Axel and UK Brain Expression Consortium and Int Headache Genetics Consortium and North Amer Brain Expression and the International Headache Genetics Consortium and North American Brain Expression Consortium
Nature genetics, ISSN 1061-4036, 08/2013, Volume 45, Issue 8, pp. 912 - U255
POPULATION | HUMAN-DISEASE | PROTEIN | NEURITE OUTGROWTH | DOWN-REGULATION | TRANSFORMING-GROWTH-FACTOR | PROTEOLYSIS | ASSOCIATION | EXPRESSION | FAMILY | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic susceptibility | Genetic variation | Migraine | Physiological aspects | Genetic aspects | Research | Risk factors | Studies | Proteins | Signal transduction | Headaches | Population | Genomes | Meta-analysis | Index Medicus
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3. Full Text Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition
by Small, Kerrin S and Todorčević, Marijana and Civelek, Mete and El-Sayed Moustafa, Julia S and Wang, Xiao and Simon, Michelle M and Fernandez-Tajes, Juan and Mahajan, Anubha and Horikoshi, Momoko and Hugill, Alison and Glastonbury, Craig A and Quaye, Lydia and Neville, Matt J and Sethi, Siddharth and Yon, Marianne and Pan, Calvin and Che, Nam and Viñuela, Ana and Tsai, Pei-Chien and Nag, Abhishek and Buil, Alfonso and Thorleifsson, Gudmar and Raghavan, Avanthi and Ding, Qiurong and Morris, Andrew P and Bell, Jordana T and Thorsteinsdottir, Unnur and Stefansson, Kari and Laakso, Markku and Dahlman, Ingrid and Arner, Peter and Gloyn, Anna L and Musunuru, Kiran and Lusis, Aldons J and Cox, Roger D and Karpe, Fredrik and McCarthy, Mark I
Nature genetics, ISSN 1061-4036, 04/2018, Volume 50, Issue 4, pp. 572 - 580
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genomic Imprinting | Diabetes Mellitus, Type 2 - genetics | Humans | Male | Lipogenesis - genetics | Body Composition - genetics | Female | Body Fat Distribution | Kruppel-Like Transcription Factors - deficiency | Gene Expression | Genome-Wide Association Study | Mice, Inbred C57BL | Risk Factors | Cell Size | Sex Characteristics | Adipocytes - pathology | Mice, Knockout | Phenotype | Animals | Enhancer Elements, Genetic | Alleles | Mice | Sp Transcription Factors - genetics | Diabetes Mellitus, Type 2 - pathology | Kruppel-Like Transcription Factors - genetics | Type 2 diabetes | Fat cells | Rats as laboratory animals | Genetic aspects | Research | Gene expression | Risk factors | Haplotypes | Adipose tissue | Body fat | Dyslipidemia | Risk | Genomes | Adipocytes | Body composition | Clonal deletion | Body composition (biology) | Animal tissues | DNA methylation | Lipogenesis | Diabetes mellitus (non-insulin dependent) | Bioinformatics | Deoxyribonucleic acid--DNA | Phenotypes | Diabetes mellitus | Health risks | Insulin | Body size | Insulin resistance | Gene loci | Diabetes | Cell size | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Therapeutic efficacy of artemether-lumefantrine combination in the treatment of uncomplicated malaria among children under five years of age in three ecological zones in Ghana
by Abuaku, Benjamin and Duah, Nancy and Quaye, Lydia and Quashie, Neils and Koram, Kwadwo
Malaria journal, ISSN 1475-2875, 2012, Volume 11, Issue 1, pp. 388 - 388
Therapeutic efficacy | Uncomplicated malaria | Ecological zones | Ghana | Artemether-lumefantrine | Infectious Diseases | Parasitology | Life Sciences & Biomedicine | Science & Technology | Tropical Medicine | Prospective Studies | Humans | Artemisinins - administration & dosage | Child, Preschool | Infant | Male | Treatment Outcome | Ethanolamines - administration & dosage | Antimalarials - administration & dosage | Female | Fluorenes - administration & dosage | Malaria - drug therapy | Drug Combinations | Decision-making | Children | Malaria | Drug therapy | Analysis | Studies | Health sciences | Hospitals | Mortality | Parasites | Drug resistance | Index Medicus
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5. Full Text Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine combinations for uncomplicated malaria in 10 sentinel sites across Ghana: 2015-2017
by Abuaku, Benjamin and Duah-Quashie, Nancy O and Quaye, Lydia and Matrevi, Sena A and Quashie, Neils and Gyasi, Akosua and Owusu-Antwi, Felicia and Malm, Keziah and Koram, Kwadwo
Malaria journal, ISSN 1475-2875, 06/2019, Volume 18, Issue 1, pp. 206 - 206
Infectious Diseases | Parasitology | Life Sciences & Biomedicine | Science & Technology | Tropical Medicine | Drug therapy, Combination | Children | Malaria | Drug therapy | Patient outcomes | Diseases | Therapeutic efficacy | Uncomplicated malaria | Artesunate–amodiaquine | Ghana | Artemether–lumefantrine | Sentinel sites
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6. Full Text The Genetic Architecture of the Human Immune System: A Bioresource for Autoimmunity and Disease Pathogenesis
by Roederer, Mario and Quaye, Lydia and Mangino, Massimo and Beddall, Margaret H and Mahnke, Yolanda and Chattopadhyay, Pratip and Tosi, Isabella and Napolitano, Luca and Terranova Barberio, Manuela and Menni, Cristina and Villanova, Federica and Di Meglio, Paola and Spector, Tim D and Nestle, Frank O
Cell (Cambridge), ISSN 0092-8674, 04/2015, Volume 161, Issue 2, pp. 387 - 403
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genetic Predisposition to Disease | Genome-Wide Association Study | Immune System Diseases - genetics | Humans | Middle Aged | Immunophenotyping | Autoimmune Diseases - genetics | Receptors, IgG - genetics | T-Lymphocytes, Regulatory - cytology | Adult | Female | Aged | Polymorphism, Single Nucleotide | Leukocytes - cytology | Autoimmunity | Genetic research | T cells | Twins | Analysis | Immune system | Index Medicus
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7. Full Text Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
by Lee, J.J and Wedow, R and Okbay, A and Kong, E and Maghzian, O and Zacher, M and Galesloot, T.E and Kiemeney, L.A.L.M and Franke, B and Benjamin, D.J and Cesarini, D and 23Me Res Team and Social Sci Genetic Assoc Consortiu and COGENT Cognitive Genomics Consorti and 23andMe Research Team and COGENT (Cognitive Genomics Consortium) and Social Science Genetic Association Consortium and Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Department of Obstetrics and Gynecology and Sahlgrenska Academy
Nature genetics, ISSN 1061-4036, 2018, Volume 50, Issue 8, pp. 1112 - 1121
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Humans | Middle Aged | Male | Educational Status | Multifactorial Inheritance | Phenotype | Aged, 80 and over | Adult | Female | Aged | Polymorphism, Single Nucleotide | Genome-Wide Association Study - methods | Cohort Studies | Cell interaction | Genome-wide association studies | Usage | Analysis | Multifactorial traits | Research | Health education | Brain | Phenotypes | Dosage compensation | Sample size | Cognitive ability | Association analysis | Genomes | Single-nucleotide polymorphism | Gene expression | Estimates | Environmental effects | Educational attainment | Meta-analysis | Consortia | Education | X Chromosomes | Genetic analysis | Heritability | Index Medicus | Clinical Medicine | Obstetrics, Gynecology and Reproductive Medicine | Reproduktionsmedicin och gynekologi | Klinisk medicin
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8. Full Text Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families
by Gormley, Padhraig and Kurki, Mitja I and Hiekkala, Marjo Eveliina and Veerapen, Kumar and Häppölä, Paavo and Mitchell, Adele A and Lal, Dennis and Palta, Priit and Surakka, Ida and Kaunisto, Mari Anneli and Hämäläinen, Eija and Vepsäläinen, Salli and Havanka, Hannele and Harno, Hanna and Ilmavirta, Matti and Nissilä, Markku and Säkö, Erkki and Sumelahti, Marja-Liisa and Liukkonen, Jarmo and Sillanpää, Matti and Metsähonkala, Liisa and Koskinen, Seppo and Lehtimäki, Terho and Raitakari, Olli and Männikkö, Minna and Ran, Caroline and Belin, Andrea Carmine and Jousilahti, Pekka and Anttila, Verneri and Salomaa, Veikko and Artto, Ville and Färkkilä, Markus and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bell, Robert K and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Furlotte, Nicholas A and Huber, Karen E and Kleinman, Aaron and Litterman, Nadia K and McCreight, Jennifer C and McIntyre, Matthew H and Mountain, Joanna L and Northover, Carrie A.M and Pitts, Steven J and Sathirapongsasuti, J. Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tian, Chao and Tung, Joyce Y and Vacic, Vladimir and Wilson, Catherine H and Anttila, Verneri and Artto, Ville and Belin, Andrea Carmine and Boomsma, Dorret I and Børte, Sigrid and Chasman, Daniel I and Cherkas, Lynn and Christensen, Anne Francke and Cormand, Bru and Cuenca-Leon, Ester and Davey-Smith, George and Dichgans, Martin and van Duijn, Cornelia and Esko, Tonu and Esserlind, Ann-Louise and Ferrari, Michel D and Frants, Rune R and Freilinger, Tobias and Furlotte, Nick and Gormley, Padhraig and Griffiths, Lyn and Hamalainen, Eija and Hansen, Thomas Folkmann and Hiekkala, Marjo and Ikram, M Arfan and Ingason, Andres and Järvelin, Marjo-Riitta and Kajanne, Risto and Kallela, Mikko and Kaprio, Jaakko and Kaunisto, Mari and Kubisch, Christian and Kurki, Mitja and Kurth, Tobias and Launer, Lenore and Lehtimaki, Terho and Lessel, Davor and Ligthart, Lannie and Litterman, Nadia and van den Maagdenberg, Arn and Macaya, Alfons and Malik, Rainer and Mangino, Massimo and McMahon, George and ... and 23andMe Research Team and International Headache Genetics Consortium (IHGC) and Int Headache Genetics Consortium and 23me Res Team
Neuron (Cambridge, Mass.), ISSN 0896-6273, 05/2018, Volume 98, Issue 4, pp. 743 - 753.e4
PRS | migraine | GWAS | genome-wide association study | familial aggregation | migraine with aura | hemiplegic migraine | disease aggregation | families | polygenic risk score | Neuroscience(all) | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Genetic Predisposition to Disease | Genome-Wide Association Study | Humans | Middle Aged | Genotype | Male | Multifactorial Inheritance | Genetic Variation | Migraine without Aura - genetics | Phenotype | Migraine Disorders - genetics | Adult | Female | Migraine with Aura - genetics | Migraine | Genetic aspects | Studies | Headache | Disease | Headaches | Population | Genomes | Heredity | Mutation | Polygenic inheritance | Medicin och hälsovetenskap
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