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Journal of Clinical Investigation, ISSN 0021-9738, 09/2015, Volume 125, Issue 9, pp. 3505 - 3518
The regulatory microRNA miR-150 is involved in the development of hemopathies and is downregulated in T-lymphomas, such as anaplastic large-cell lymphoma... 
ANAPLASTIC LYMPHOMA KINASE | MEDICINE, RESEARCH & EXPERIMENTAL | DNA METHYLTRANSFERASE 1 | LUNG-CANCER | TUMOR-SUPPRESSOR MICRORNAS | NPM-ALK | TYROSINE KINASE | THERAPEUTIC TARGET | DOWN-REGULATION | C-MYB | ACTIVATING MUTATIONS | Protein-Tyrosine Kinases - metabolism | Humans | Gene Expression Regulation, Neoplastic | Drug Resistance, Neoplasm | Male | DNA (Cytosine-5-)-Methyltransferases - metabolism | Protein-Tyrosine Kinases - genetics | Female | Lymphoma, Large-Cell, Anaplastic - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Lymphoma, Large-Cell, Anaplastic - genetics | Pyrazoles - pharmacology | DNA (Cytosine-5-)-Methyltransferase 1 | Gene Silencing | Mice, Transgenic | MicroRNAs - biosynthesis | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | RNA, Neoplasm - biosynthesis | Lymphoma, Large-Cell, Anaplastic - drug therapy | Cell Line, Tumor | RNA, Neoplasm - genetics | Lymphoma, Large-Cell, Anaplastic - pathology | Mice | MicroRNAs - genetics | Pyridines - pharmacology | Crizotinib | Usage | MicroRNA | Genetic aspects | Research | Non-Hodgkin's lymphomas | Health aspects | Risk factors | Disease | Kinases | Gene expression | Cancer therapies | Chemotherapy | Disadvantages | Medical prognosis | MicroRNAs | DNA methylation | Epigenetics | Lymphomas | Mutation | Deoxyribonucleic acid--DNA | Tumors | Cancer | Life Sciences
Journal Article
The Journal of Pathology, ISSN 0022-3417, 07/2017, Volume 242, Issue 3, pp. 347 - 357
Journal Article
Oncogene, ISSN 0950-9232, 11/2005, Volume 24, Issue 48, pp. 7248 - 7252
Several tyrosine kinase genes are involved in chromosomal translocations in chronic myeloproliferative disorders, but there are still uncharacterized... 
JAK2 | PCM1 | Atypical chronic myeloid leukaemia | TARGET | PDGFRA | POLYCYTHEMIA-VERA | BIOCHEMISTRY & MOLECULAR BIOLOGY | atypical chronic myeloid leukaemia | RECEPTOR | CELL BIOLOGY | BCR | ONCOLOGY | CHRONIC MYELOPROLIFERATIVE DISORDERS | MUTATION | GENETICS & HEREDITY | TYROSINE KINASE JAK2 | CARCINOMA | Translocation, Genetic | Cytarabine - therapeutic use | Humans | Middle Aged | Open Reading Frames | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Male | Antineoplastic Agents - therapeutic use | Proto-Oncogene Proteins - chemistry | Secondary Prevention | Cell Cycle Proteins - chemistry | Genetic Variation | Janus Kinase 2 | Protein-Tyrosine Kinases - genetics | Karyotyping | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Fatal Outcome | Protein-Tyrosine Kinases - chemistry | Cell Cycle Proteins - genetics | Idarubicin - therapeutic use | Protein Structure, Tertiary | RNA, Messenger - genetics | Autoantigens | In Situ Hybridization, Fluorescence | Proto-Oncogene Proteins - genetics | Treatment Outcome | Chromosomes, Human, Pair 8 | Chromosomes, Human, Pair 9 | Reverse Transcriptase Polymerase Chain Reaction | Antimetabolites, Antineoplastic - therapeutic use | Sequence Analysis, RNA | Antibiotics, Antineoplastic - therapeutic use | Oncogene Proteins, Fusion - genetics | Hydroxyurea - therapeutic use
Journal Article
Haematologica, ISSN 0390-6078, 01/2019, Volume 104, Issue 2, pp. 347 - 359
Anaplastic large-cell lymphoma, a T-cell neoplasm, is primarily a pediatric disease. Seventy-five percent of pediatric anaplastic large-cell lymphoma cases... 
Life Sciences | Cancer
Journal Article
Haematologica, ISSN 0390-6078, 01/2019, Volume 104, Issue 2, pp. 347 - 359
Anaplastic large-cell lymphoma, a T-cell neoplasm, is primarily a pediatric disease. Seventy-five percent of pediatric anaplastic large-cell lymphoma cases... 
ANAPLASTIC LYMPHOMA KINASE | PATHOGENESIS | DOWN-REGULATION | NPM | PROLIFERATION | MICRORNAS | INHIBITOR | HEMATOLOGY | UP-REGULATION | TUMOR-GROWTH | EXPRESSION | Life Sciences | Human health and pathology | Immunology | Hematology | Immunotherapy | Cancer
Journal Article
Oncotarget, ISSN 1949-2553, 2018, Volume 9, Issue 18, pp. 14539 - 14551
Systemic anaplastic large-cell lymphoma (ALCL) is a childhood T cell neoplasm defined by the presence or absence of translocations that lead to the ectopic... 
DNMT1 | MiR-125b | Doxorubicin | DNA topoisomerase II | Chemoresistance | Life Sciences | Human health and pathology | Hematology | Cancer
Journal Article
The Journal of Experimental Medicine, ISSN 0022-1007, 10/2008, Volume 205, Issue 11, pp. 2499 - 2506
textabstractMost chromosomal translocations in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) involve oncogenes that are either up-regulated... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNOLOGY | CANCER | MICRORNA SIGNATURES | GENES | Brief Definitive Reports
Journal Article
British Journal of Haematology, ISSN 0007-1048, 04/2015, Volume 169, Issue 2, pp. 290 - 293
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2018, Volume 115, Issue 41, p. 10357
PAX5 is a well-known haploinsufficient tumor suppressor gene in human B-cell precursor acute lymphoblastic leukemia (B-ALL) and is involved in various... 
Cell proliferation | Translocation | Transformation | Acute lymphatic leukemia | Leukemia | Elastin | Lymphatic leukemia | Pax5 protein | Cells | Proteins | Chromosome translocations | Lymphocytes B | Computer applications | Protein expression | Tumor suppressor genes | Tumorigenesis | Mice | In vivo methods and tests | Mutation | Fusion protein
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2018, Volume 115, Issue 41, pp. 10357 - 10362
Journal Article
Journal Article
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