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index medicus (155) 155
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animals (123) 123
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male (91) 91
pain (74) 74
essential oil (66) 66
chemistry, medicinal (65) 65
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formalin test (41) 41
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carvacrol (28) 28
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analgesics - therapeutic use (27) 27
cyclodextrins (27) 27
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pharmacy and materia medica (27) 27
plant extracts - pharmacology (27) 27
beta-cyclodextrin (26) 26
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plant sciences (26) 26
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monoterpenes - pharmacology (24) 24
natural products (24) 24
oxidative stress (24) 24
dose-response relationship, drug (23) 23
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cyclodextrin (22) 22
monoterpenes (22) 22
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essential oils (19) 19
mechanisms (19) 19
monoterpenes - therapeutic use (19) 19
neurosciences (19) 19
acetic acid (18) 18
anti-inflammatory agents - pharmacology (18) 18
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food science & technology (18) 18
hyperalgesia - drug therapy (18) 18
in-vitro (18) 18
plant leaves - chemistry (18) 18
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antinociceptive activity (17) 17
fibromyalgia (17) 17
formaldehyde (17) 17
glutamate (17) 17
oils, volatile - pharmacology (17) 17
review (17) 17
article subject (16) 16
inclusion complex (16) 16
nitric-oxide (16) 16
nociception - drug effects (16) 16
oils, volatile - chemistry (16) 16
plant extracts - therapeutic use (16) 16
β-cyclodextrin (16) 16
analgesics (15) 15
analgesics - chemistry (15) 15
beta-cyclodextrins - chemistry (15) 15
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plant extracts - chemistry (13) 13
terpenes (13) 13
anti-inflammatory activity (12) 12
anti-inflammatory agents - therapeutic use (12) 12
atividade antinociceptiva (12) 12
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Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 12/2015, Volume 16, Issue 1, pp. 547 - 563
O. basilicum leaves produce essential oils (LEO) rich in monoterpenes. The short half-life and water insolubility are limitations for LEO medical uses.... 
Fibromyalgia | Essential oil | Pain | Fos protein | β-cyclodextrin | Ocimum basilicum | pain | fos protein | BIOCHEMISTRY & MOLECULAR BIOLOGY | INVOLVEMENT | (-)-LINALOOL | MECHANISMS | CHEMISTRY, MULTIDISCIPLINARY | MONOTERPENES | fibromyalgia | INJECTION | P-CYMENE | beta-cyclodextrin | INCLUSION | essential oil | NOCICEPTION | MODULATION | LEAF ESSENTIAL OIL | Central Nervous System - metabolism | Oils, Volatile - chemistry | Motor Activity - drug effects | Male | Oils, Volatile - therapeutic use | Fibromyalgia - drug therapy | Monoterpenes - administration & dosage | Oils, Volatile - administration & dosage | Hand Strength | Monoterpenes - therapeutic use | Analgesics - isolation & purification | Plant Leaves - chemistry | Analgesics - therapeutic use | Monoterpenes - isolation & purification | Fibromyalgia - genetics | Analgesics - administration & dosage | Oils, Volatile - isolation & purification | Hyperalgesia - physiopathology | Up-Regulation - drug effects | Animals | beta-Cyclodextrins - chemistry | Hyperalgesia - drug therapy | Hyperalgesia - genetics | Analgesics - chemistry | Central Nervous System - drug effects | Monoterpenes - chemistry | Ocimum basilicum - chemistry | Proto-Oncogene Proteins c-fos - genetics | Mice | Central Nervous System - physiopathology | Fibromyalgia - physiopathology | Proteins | Oils & fats | Protein expression
Journal Article
Oxidative Medicine and Cellular Longevity, ISSN 1942-0900, 01/2015, Volume 2015, pp. 171756 - 9
Journal Article
Journal Article
Journal Article
Journal Article
Evidence-based Complementary and Alternative Medicine, ISSN 1741-427X, 2015, Volume 2015, p. 502454
This study aimed to evaluate the orofacial antinociceptive effect of the Cymbopogon winterianus essential oil (LEO) complexed in beta-cyclodextrin (LEO-CD) and... 
NEUROPATHIC PAIN | OROFACIAL FORMALIN TEST | RAT | PHYSICOCHEMICAL CHARACTERIZATION | INTEGRATIVE & COMPLEMENTARY MEDICINE | NATURAL-PRODUCTS | P-CYMENE | CENTRAL-NERVOUS-SYSTEM | CHANNELS | MICE | LOCUS-COERULEUS NEURONS
Journal Article