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Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 7, pp. 984 - 993
Summary Background BRAF mutations act as an oncogenic driver via the mitogen-activated protein kinase (MAPK) pathway in non-small cell lung cancer (NSCLC).... 
Hematology, Oncology and Palliative Medicine
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 5, pp. 642 - 650
Summary Background Activating BRAFV600E (Val600Glu) mutations are found in about 1–2% of lung adenocarcinomas, which might provide an opportunity for targeted... 
Hematology, Oncology and Palliative Medicine
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 2, pp. 212 - 223
Summary Background MUC1 is a tumour-associated antigen expressed by many solid tumours, including non-small-cell lung cancer. TG4010 is a modified vaccinia... 
Hematology, Oncology and Palliative Medicine | ONCOLOGY | MVA-MUC1-IL2 | PROSTATE-CANCER | VACCINE | Predictive Value of Tests | Carcinoma, Non-Small-Cell Lung - chemistry | Humans | Middle Aged | Fatigue - etiology | Male | Cisplatin - administration & dosage | Antigens, CD - analysis | Antigens, Differentiation, T-Lymphocyte - analysis | Neutropenia - etiology | Cancer Vaccines - therapeutic use | Receptors, IgG - analysis | Mucin-1 - analysis | Lectins, C-Type - analysis | Female | Paclitaxel - administration & dosage | Lymphocytes - chemistry | Anemia - etiology | Bevacizumab - administration & dosage | Double-Blind Method | Lung Neoplasms - chemistry | Lymphocyte Activation | CD56 Antigen - analysis | Deoxycytidine - administration & dosage | Erlotinib Hydrochloride - administration & dosage | Carboplatin - administration & dosage | Cancer Vaccines - adverse effects | Lung Neoplasms - therapy | Immunotherapy - adverse effects | Biomarkers, Tumor - blood | Disease-Free Survival | Carcinoma, Non-Small-Cell Lung - therapy | Membrane Glycoproteins - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Pemetrexed - administration & dosage | Aged | Membrane Glycoproteins - adverse effects | Deoxycytidine - analogs & derivatives | Antigens | Fc receptors | Hospitals | Interleukins | Immunotherapy | Mucins | Clinical trials | Product development | Lung cancer, Non-small cell | Analysis
Journal Article
Lancet, The, ISSN 0140-6736, 2011, Volume 378, Issue 9796, pp. 1079 - 1088
Summary Background Platinum-based doublet chemotherapy is recommended to treat advanced non-small-cell lung cancer (NSCLC) in fit, non-elderly adults, but... 
Internal Medicine | SURVIVAL | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | INTERNATIONAL-SOCIETY | GERIATRIC ASSESSMENT | UNDERREPRESENTATION | OLDER | OUTCOMES | COMBINATION | AGE | COMORBIDITY | Lung Neoplasms - drug therapy | Lung Neoplasms - mortality | Humans | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Antineoplastic Agents - therapeutic use | Vinblastine - administration & dosage | Carboplatin - adverse effects | Carcinoma, Squamous Cell - mortality | Vinblastine - analogs & derivatives | Antineoplastic Agents - adverse effects | Aged, 80 and over | Female | Paclitaxel - administration & dosage | Drug Administration Schedule | Deoxycytidine - administration & dosage | Carboplatin - administration & dosage | Paclitaxel - adverse effects | Survival Rate | Adenocarcinoma - drug therapy | Carcinoma, Non-Small-Cell Lung - mortality | Carcinoma, Squamous Cell - drug therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Deoxycytidine - analogs & derivatives | Adenocarcinoma - mortality | Clinical trials | Chemotherapy | Radiation therapy | Cancer therapies | Adenocarcinoma | Vinblastine | Carcinoma, Non-Small-Cell Lung | Antineoplastic Agents | Antineoplastic Combined Chemotherapy Protocols | Lung Neoplasms | Carcinoma, Squamous Cell | Life Sciences | Deoxycytidine | Paclitaxel | Carboplatin | Cancer
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2011, Volume 12, Issue 12, pp. 1125 - 1133
Summary Background Chemotherapy is the standard of care for advanced stages of non-small-cell lung cancer (NSCLC). TG4010 is a targeted immunotherapy based on... 
Hematology, Oncology and Palliative Medicine | DOUBLE-BLIND | PROGNOSTIC-FACTORS | GENE | ONCOLOGY | EXPRESSION | Lung Neoplasms - drug therapy | Lung Neoplasms - mortality | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Lung Neoplasms - pathology | Male | Vaccinia virus - genetics | Antimetabolites, Antineoplastic - administration & dosage | Cisplatin - administration & dosage | Cancer Vaccines - therapeutic use | Interleukin-2 - immunology | Time Factors | Adult | Female | Chemotherapy, Adjuvant | Carcinoma, Non-Small-Cell Lung - pathology | Risk Assessment | Deoxycytidine - administration & dosage | Europe | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Cancer Vaccines - adverse effects | Treatment Outcome | Chi-Square Distribution | Carcinoma, Non-Small-Cell Lung - mortality | Carcinoma, Non-Small-Cell Lung - immunology | Disease-Free Survival | Interleukin-2 - genetics | Carcinoma, Non-Small-Cell Lung - therapy | Lung Neoplasms - immunology | Membrane Glycoproteins - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Mucin-1 - immunology | Vaccines, Synthetic | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasm Staging | Membrane Glycoproteins - adverse effects | Deoxycytidine - analogs & derivatives | Mucin-1 - genetics | Index Medicus | Interleukin-2 | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Life Sciences | Cancer Vaccines | Membrane Glycoproteins | Antineoplastic Combined Chemotherapy Protocols | Cisplatin | Mucin-1 | Vaccinia virus | Deoxycytidine | Antimetabolites, Antineoplastic | Cancer
Journal Article
Journal Article
by Mercié, Patrick and Arsandaux, Julie and Katlama, Christine and Ferret, Samuel and Beuscart, Claude and Beuscart, Aurélie and Spadone, Christian and Duvivier, Claudine and Reynes, Jacques and Wirth, Nathalie and Moinot, Laetitia and Bénard, Antoine and Zucman, David and Duval, Xavier and Molina, Jean-Michel and Spire, Bruno and Fagard, Catherine and Chêne, Geneviève and Allaguy-Salachy, Hélène and Aubin, Henri-Jean and Bernard-Henry, Claudine and Borgne, Anne and Bouchaud, Olivier and Brahmy, Charles and Breilh, Dominique and Cabié, André and Cateland, Claude and Cheret, Antoine and Couffin-Cadiergues, Sandrine and Dautzenberg, Marie-Dominique and Dellamonica, Pierre and Denis-Kandel, Pascale and Denis-Vatant, Christine and Detilleux, Michel and Dupon, Michel and El Harrar, Brigitte and Fagnen Sylvaire, Marie Christine and Guillermet, Simone and Jacomet, Christine and Jeantils, Vincent and Korzek, Marek and Lazaro, Estibaliz and Le Maitre, Béatrice and Lucht, Frédéric and Maquet, Marianne and Mathieu, Audrey and May, Thierry and Merigeaud, Sonia and Morlat, Philippe and Naqvi, Alissa and Neau, Didier and Perriot, Jean and Pierre-François, Sandrine and Poizot-Martin, Isabelle and Quoix, Elisabeth and Rebillard, Matthieu and Roussillon, Caroline and Rosenthal, Eric and Sainte-Marie, Thierry and Salmon-Céron, Dominique and Schneider, Luminita and Simon, Anne and Soussi, Malika and Sotto, Albert and Taburet, Anne-Marie and Teicher, Elina and Termote, Monique and Trosini-Desert, Valery and Verdon, Renaud and Viard, Jean-Paul and Vittecoq, Daniel and Vray, Muriel and Youssi, David and ANRS 144 Inter-ACTIV Study Grp and ANRS 144 Inter-ACTIV study group
The Lancet HIV, ISSN 2352-3018, 03/2018, Volume 5, Issue 3, pp. e126 - e135
Tobacco smoking is common in people living with HIV, but high-quality evidence on interventions for smoking cessation is not available in this population. We... 
MORTALITY | POPULATION | INFECTIOUS DISEASES | INFECTED INDIVIDUALS | PLACEBO | MYOCARDIAL-INFARCTION | SMOKERS | DISEASE | ADULTS | IMMUNOLOGY | RECEPTOR PARTIAL AGONIST | INTERVENTION | Life Sciences | Santé publique et épidémiologie
Journal Article
Cancer, ISSN 0008-543X, 05/2003, Volume 97, Issue 9, pp. 2308 - 2317
BACKGROUND Determination of tumor clonality has implications for molecular characterization and the optimal treatment of cancer. Allelotyping allows detection... 
alternative allelic imbalance | synchronous liver metastasis | colorectal carcinoma | plasma DNA | lung carcinoma | allelotyping | Allelotyping | Lung carcinoma | Synchronous liver metastasis | Alternative allelic imbalance | Colorectal carcinoma | Plasma DNA | LOSSES | ADENOCARCINOMA | SUPPRESSOR GENES | CHROMOSOME 3P | CANCER | HETEROZYGOSITY | LESIONS | CARCINOGENESIS | ONCOLOGY | COMPARATIVE GENOMIC HYBRIDIZATION | PROGRESSION | Carcinoma, Squamous Cell - blood | Adenocarcinoma - pathology | Carcinoma, Small Cell - genetics | Prognosis | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Allelic Imbalance | DNA, Neoplasm - blood | Polymerase Chain Reaction | Adult | Female | Adenocarcinoma - genetics | Lung Neoplasms - genetics | Colorectal Neoplasms - blood | Adenocarcinoma - blood | Gene Frequency | Carcinoma, Small Cell - blood | Disease Progression | Genetic Heterogeneity | Microsatellite Repeats - genetics | Aged | Lung Neoplasms - blood | DNA, Neoplasm - genetics | Carcinoma, Small Cell - pathology | Colorectal Neoplasms - pathology | Care and treatment | Lung cancer | Oncology, Experimental | Colorectal cancer | Research | Carcinogenesis | Biological diversity | DNA | Analysis | Liver tumors | Genetic aspects | Health aspects | Methods | Tumors
Journal Article
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