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1. Full Text Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
by Elden, Andrew C and Kim, Hyung-Jun and Hart, Michael P and Chen-Plotkin, Alice S and Johnson, Brian S and Fang, Xiaodong and Armakola, Maria and Geser, Felix and Greene, Robert and Lu, Min Min and Padmanabhan, Arun and Clay-Falcone, Dana and McCluskey, Leo and Elman, Lauren and Juhr, Denise and Gruber, Peter J and Rüb, Udo and Auburger, Georg and Trojanowski, John Q and Lee, Virginia M.-Y and Van Deerlin, Vivianna M and Bonini, Nancy M and Gitler, Aaron D
Nature (London), ISSN 0028-0836, 08/2010, Volume 466, Issue 7310, pp. 1069 - 1075
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Drosophila - drug effects | Neurons - pathology | Saccharomyces cerevisiae - genetics | Humans | Middle Aged | Peptides - genetics | Male | Saccharomyces cerevisiae - drug effects | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Young Adult | Ataxins | Aged, 80 and over | Adult | Female | Drosophila - genetics | Cell Line | Genetic Predisposition to Disease | Peptides - chemistry | Amyotrophic Lateral Sclerosis - genetics | DNA-Binding Proteins - toxicity | Risk Factors | Repetitive Sequences, Amino Acid - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Aged | Proteins | Yeast | Insects | Pathogenesis | Toxicity | Genes | Genetics | Amyotrophic lateral sclerosis | Mutation | Kinases | Health risk assessment | Index Medicus
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2. Full Text Neuroanatomical characteristics of the human pre-Bötzinger complex and its involvement in neurodegenerative brainstem diseases
by Schwarzacher, Stephan W and Rüb, Udo and Deller, Thomas
Brain (London, England : 1878), ISSN 0006-8950, 2011, Volume 134, Issue 1, pp. 24 - 35
respiratory control | brainstem | multiple system atrophy | spinocerebellar ataxia | pre-Bötzinger complex | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Biological and medical sciences | Medical sciences | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Immunohistochemistry | Neurons - pathology | Multiple System Atrophy - pathology | Cell Count | Humans | Middle Aged | Male | Spinocerebellar Ataxias - physiopathology | Spinocerebellar Ataxias - metabolism | Spinocerebellar Ataxias - pathology | Multiple System Atrophy - metabolism | Neurons - physiology | Aged, 80 and over | Female | Medulla Oblongata - pathology | Receptors, Neurokinin-1 - metabolism | Aged | Multiple System Atrophy - physiopathology | Respiration | Medulla Oblongata - physiology | Somatostatin - metabolism | Index Medicus | Abridged Index Medicus
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3. Full Text Axonal inclusions in spinocerebellar ataxia type 3
by Seidel, Kay and den Dunnen, Wilfred F. A and Schultz, Christian and Paulson, Henry and Frank, Stefanie and de Vos, Rob A and Brunt, Ewout R and Deller, Thomas and Kampinga, Harm H and Rueb, Udo
Acta neuropathologica, ISSN 0001-6322, 10/2010, Volume 120, Issue 4, pp. 449 - 460
TAU-PROTEIN | Ataxin-3 | SCA3 | SCA3 PATIENTS | BRAIN-STEM | GLIAL INCLUSIONS | Polyglutamine diseases | UMCG Approved | Protein aggregates | NEURONAL INTRANUCLEAR INCLUSIONS | PRECEREBELLAR NUCLEI | MULTIPLE SYSTEM ATROPHY | MACHADO-JOSEPH-DISEASE | BINDING | Axonal aggregates | Pathology | Neurosciences | Medicine & Public Health | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Tyrosine 3-Monooxygenase - metabolism | Humans | Middle Aged | Peptides - genetics | tau Proteins - metabolism | Male | Intranuclear Inclusion Bodies - pathology | Brain - metabolism | Nerve Tissue Proteins - metabolism | Axons - pathology | Axons - ultrastructure | Aged, 80 and over | Brain - pathology | Adult | Female | Aged | Intranuclear Inclusion Bodies - metabolism | Tryptophan Hydroxylase - metabolism | Machado-Joseph Disease - genetics | Machado-Joseph Disease - pathology | Ubiquitin | Nervous system diseases | Universities and colleges | Neurons | Analysis | Spinocerebellar ataxia | Index Medicus | Original Paper
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4. Full Text Brain pathology of spinocerebellar ataxias
by Seidel, Kay and Siswanto, Sonny and Brunt, Ewout R. P and den Dunnen, Wilfred and Korf, Horst-Werner and Rueb, Udo
Acta neuropathologica, ISSN 0001-6322, 07/2012, Volume 124, Issue 1, pp. 1 - 21
Cerebellum | PALLIDOLUYSIAN ATROPHY DRPLA | Neuropathology | Polyglutamine diseases | CLINICAL-FEATURES | UMCG Approved | NEURONAL INTRANUCLEAR INCLUSIONS | TATA-BINDING PROTEIN | GERMAN KINDREDS | Spinocerebellar ataxia | MACHADO-JOSEPH-DISEASE | CAG REPEAT EXPANSION | DOMINANT CEREBELLAR-ATAXIA | ATTENUATED NUCLEAR SHRINKAGE | ADCA | TRINUCLEOTIDE REPEAT | Pathology | Neurosciences | Medicine & Public Health | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Brain - pathology | Spinocerebellar Ataxias - physiopathology | Spinocerebellar Ataxias - pathology | Humans | Spinocerebellar Ataxias - classification | Index Medicus | Neuroimaging | Transcription factors | retinal degeneration | Polyglutamine | Neurodegenerative diseases | Cerebellar ataxia | Data processing | trinucleotide repeat diseases | Ataxin | Magnetic resonance imaging | Tau protein | Purkinje cells | Inclusion bodies | Quality control | Calcification | Axonal transport | polyglutamine diseases | Brain injury
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5. Full Text Mapping local hippocampal changes in Alzheimer's disease and normal ageing with MRI at 3 Tesla
by Frisoni, Giovanni B and Ganzola, Rossana and Canu, Elisa and Rüb, Udo and Pizzini, Francesca B and Alessandrini, Franco and Zoccatelli, Giada and Beltramello, Alberto and Caltagirone, Carlo and Thompson, Paul M
Brain (London, England : 1878), ISSN 0006-8950, 12/2008, Volume 131, Issue 12, pp. 3266 - 3276
Alzheimer's disease | 3D-shape | Ageing | Magnetic resonance | Hippocampus | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Biological and medical sciences | Medical sciences | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Psychiatric Status Rating Scales | Humans | Image Interpretation, Computer-Assisted - methods | Aged, 80 and over | Magnetic Resonance Imaging - methods | Female | Male | Aged | Hippocampus - pathology | Brain Mapping - methods | Aging - pathology | Alzheimer Disease - pathology | Index Medicus | Abridged Index Medicus
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6. Full Text Spinocerebellar ataxia 2 (SCA2)
by Lastres-Becker, Isabel and Rüb, Udo and Auburger, Georg
Cerebellum (London, England), ISSN 1473-4222, 6/2008, Volume 7, Issue 2, pp. 115 - 124
Neurology | Neurosciences | Biomedicine | ataxin-2 | spinocerebellar ataxia type 2 | olivo-ponto-cerebellar atrophy | Neurobiology | neurodegeneration | Wadia-Swami or Menzel type of ataxia | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Spinocerebellar Ataxias - diagnosis | Ataxins | Diagnosis, Differential | Genes, Dominant | Cerebellar Cortex - pathology | Humans | Brain - pathology | Spinocerebellar Ataxias - pathology | Nerve Tissue Proteins - genetics | RNA - genetics | RNA - metabolism | Spinocerebellar Ataxias - genetics | Proteins | Medical research | Ataxia | Index Medicus
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7. Full Text Potentiation of neurotoxicity in double-mutant mice with Pink1 ablation and A53T-SNCA overexpression
by Gispert, Suzana and Brehm, Nadine and Weil, Jonas and Seidel, Kay and Rüb, Udo and Kern, Beatrice and Walter, Michael and Roeper, Jochen and Auburger, Georg
Human molecular genetics, ISSN 0964-6906, 02/2015, Volume 24, Issue 4, pp. 1061 - 1076
Biochemistry & Molecular Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Protein Kinases - metabolism | Protein Kinases - genetics | Spinal Cord - metabolism | Age Factors | Mesencephalon - metabolism | Transcriptome | Male | Gene Expression Profiling | Motor Activity | Brain - metabolism | Spinal Cord - pathology | Female | alpha-Synuclein - genetics | Disease Models, Animal | Mesencephalon - pathology | Gene Expression | Parkinson Disease - pathology | Computational Biology | Parkinson Disease - genetics | Mice, Knockout | Phenotype | Animals | Brain - pathology | Mice | Mutation | alpha-Synuclein - metabolism | Parkinson Disease - mortality | Index Medicus
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