Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Book / eBook (647) 647
Journal Article (299) 299
Publication (48) 48
Book Review (47) 47
Newspaper Article (36) 36
Dissertation (10) 10
Conference Proceeding (9) 9
Patent (5) 5
Book Chapter (3) 3
Magazine Article (3) 3
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (185) 185
history (178) 178
humans (157) 157
united states (75) 75
great britain (62) 62
electronic books (61) 61
history and criticism (61) 61
bibliography (59) 59
female (55) 55
male (55) 55
diseases (50) 50
animals (49) 49
biochemistry & molecular biology (46) 46
aufsatzsammlung (43) 43
dictionaries (43) 43
research (43) 43
biography (42) 42
aged (39) 39
medicine (39) 39
bibliographies (36) 36
middle aged (35) 35
abridged index medicus (34) 34
histoire (34) 34
proteins (34) 34
bible (33) 33
english literature (33) 33
adult (31) 31
analysis (31) 31
article (31) 31
cell biology (31) 31
cancer (30) 30
england (30) 30
geschichte (29) 29
historia (29) 29
biographies (28) 28
disease (28) 28
protein folding (28) 28
religion (27) 27
literature (25) 25
surgery (25) 25
criticism and interpretation (24) 24
criticism, interpretation, etc (24) 24
unfolded protein response (24) 24
bibliographie (23) 23
diagnosis (23) 23
drug therapy (23) 23
addresses, essays, lectures (22) 22
christianity (22) 22
english (22) 22
medicine & public health (22) 22
church history (21) 21
pathology (21) 21
wörterbuch (21) 21
englisch (20) 20
histoire et critique (20) 20
immunology (20) 20
methods (20) 20
politics and government (20) 20
therapy (20) 20
genetic aspects (19) 19
health aspects (19) 19
child (18) 18
medicine, general & internal (18) 18
prevention (18) 18
complications (17) 17
antiquities (16) 16
english language (16) 16
prealbumin - metabolism (16) 16
science (16) 16
sources (16) 16
20th century (15) 15
activation (15) 15
biochemistry (15) 15
civilization (15) 15
double-blind method (15) 15
encyclopedias (15) 15
engels (15) 15
handbooks, manuals, etc (15) 15
oncology (15) 15
pharmacology (15) 15
physiology (15) 15
social aspects (15) 15
studies (15) 15
toxicology (15) 15
19th century (14) 14
bible. old testament (14) 14
bio-bibliography (14) 14
follow-up studies (14) 14
general (14) 14
microbiology (14) 14
old testament (14) 14
risk factors (14) 14
treatment (14) 14
amyloidosis (13) 13
biology (13) 13
cardiovascular diseases (13) 13
chemotherapy (13) 13
dictionnaires (13) 13
dictionnaires anglais (13) 13
endoplasmic reticulum (13) 13
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Robarts - Stacks (251) 251
Gerstein Science - Stacks (143) 143
UTL at Downsview - May be requested (114) 114
Trinity College (John W Graham) - Stacks (65) 65
UofT at Mississauga - Stacks (58) 58
UofT at Scarborough - Stacks (45) 45
Victoria University E.J. Pratt - Stacks (45) 45
St. Michael's College (John M. Kelly) - 2nd Floor (40) 40
St. Michael's College (John M. Kelly) - 3rd Floor (39) 39
Victoria University Emmanuel College - Stacks (32) 32
Victoria University E.J. Pratt - Reference (29) 29
Collection Dvlpm't (Acquisitions) - Vendor file (27) 27
Collection Dvlpm't (Acquisitions) - Closed Orders (26) 26
Knox College (Caven) - Stacks (26) 26
Trinity College (John W Graham) - Storage (26) 26
Trinity College (John W Graham) - Reference (24) 24
Pontifical Inst. Mediaeval Studies - Library use only (23) 23
Online Resources - Online (22) 22
OISE - Stacks (19) 19
Regis College - Stacks (19) 19
Law (Bora Laskin) - Stacks (17) 17
Victoria University CRRS - Library use only (15) 15
Robarts - Reference (14) 14
St. Augustine's Seminary - Stacks (14) 14
St. Michael's College (John M. Kelly) - Reference (13) 13
UofT at Mississauga - Reference (12) 12
Royal Ontario Museum - Stacks (10) 10
St. Augustine's Seminary - Reference (10) 10
University College (Laidlaw) - Stacks (10) 10
Engineering & Comp. Sci. - Stacks (9) 9
Thomas Fisher Rare Book - Rare Book (9) 9
Trinity College (John W Graham) - Wycliffe Storage (8) 8
Knox College (Caven) - Reference (7) 7
OISE - Reference (7) 7
St. Michael's Hospital - Stacks (7) 7
Massey College (Robertson Davies) - Rare Book (6) 6
Music - Stacks (5) 5
Scarborough Hospital - General (5) 5
Earth Sciences (Noranda) - Stacks (4) 4
Institute for Christian Studies - Stacks (4) 4
Pontifical Inst. Mediaeval Studies - Reference (4) 4
Regis College - Reference (4) 4
Robarts - Woodhouse Collection 13th floor (4) 4
Toronto East General Hospital - Stacks (4) 4
UofT at Scarborough - Reference (4) 4
Victoria University E.J. Pratt - Northrop Frye (4) 4
Victoria University Emmanuel College - Reference (4) 4
Chemistry (A D Allen) - Stacks (3) 3
Earth Sciences (Noranda) - Reference (3) 3
Gerstein Science - Reference (3) 3
Music - Reference (3) 3
Physics - Reference (3) 3
Robarts - Library use only (3) 3
UofT at Scarborough - Withdrawn (3) 3
Victoria University Emmanuel College - Birge Storage (3) 3
Faculty of Information - Stacks (2) 2
Faculty of Information - Subject Analysis Systems (2) 2
Humber River Regional Hospital - Church Stacks (2) 2
Humber River Regional Hospital - Finch Stacks (2) 2
Knox College (Caven) - Reference Oversize (2) 2
Lakeridge Health Sciences - Oshawa (2) 2
New College (Ivey) - Stacks (2) 2
Robarts - May be requested in 6-10 wks (2) 2
St Josephs Health Centre - Reference (2) 2
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (2) 2
Thomas Fisher Rare Book - Reference (2) 2
United Church of Canada Archives - Archives (2) 2
University College (Laidlaw) - May be requested in 6-10 wks (2) 2
Victoria University E.J. Pratt - Withdrawn (2) 2
Architecture Landscape (Shore + Moffat) - Reference (1) 1
Architecture Landscape (Shore + Moffat) - Stacks (1) 1
Art - Library use only (1) 1
Astronomy & Astrophysics - Reference (1) 1
Chemistry (A D Allen) - Reference (1) 1
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
Collection Dvlpm't (Acquisitions) - On order (1) 1
Collection Dvlpm't (Acquisitions) - Stacks (1) 1
Credit Valley Hospital - Stacks (1) 1
Criminology - Stacks (1) 1
Dentistry (Harry R Abbott) - Withdrawn (1) 1
Earth Sciences (Noranda) - Missing (1) 1
Engineering & Comp. Sci. - Missing (1) 1
Faculty of Information - May be requested in 6-10 wks (1) 1
Gerstein Science - Missing (1) 1
Humber River Regional Hospital - Departmental Stacks (1) 1
Indust. Rel's & Hum. Resources (Newman) - Library use only (1) 1
Innis College - Stacks (1) 1
Institute for Christian Studies - May be requested (1) 1
Knox College (Caven) - Missing (1) 1
Knox College (Caven) - Storage (1) 1
Law (Bora Laskin) - Reserve desk (1) 1
Mathematical Sciences - Stacks (1) 1
Mt Sinai Hospital - Stacks (1) 1
Music - Library use only (1) 1
New College (Ivey) - Withdrawn (1) 1
OISE - Bindery (1) 1
OISE - Curriculum Resources (1) 1
OISE - Material is damaged (1) 1
OISE - Reference Desk (1) 1
Pontifical Inst. Mediaeval Studies - Guest (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1005) 1005
German (25) 25
Spanish (22) 22
French (14) 14
Arabic (3) 3
Czech (3) 3
Hebrew (3) 3
Japanese (3) 3
Italian (2) 2
Latin (2) 2
Turkish (2) 2
Ancient Greek (1) 1
Chinese (1) 1
Russian (1) 1
Swedish (1) 1
Ugaritic (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Lining up for quality control: linear ubiquitin and proteotoxicity
by Wiseman, RL
EMBO JOURNAL, ISSN 0261-4189, 05/2019, Volume 38, Issue 9, p. e101985
The post-translational modification of proteins with linear ubiquitin (Ub) has previously been shown to be important for regulating inflammatory and... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Proteins | Neurological diseases | Ubiquitin | Immunology | Neurodegenerative diseases | Pathogenesis | Quality control | Inflammation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text PERK Signaling Regulates Extracellular Proteostasis of an Amyloidogenic Protein During Endoplasmic Reticulum Stress
by Romine, Isabelle C and Wiseman, R. Luke
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 410 - 11
The PERK arm of the unfolded protein response (UPR) regulates cellular proteostasis and survival in response to endoplasmic reticulum (ER) stress. However, the... 
IN-VITRO | ACTIVATION | TRANSTHYRETIN | ER STRESS | MULTIDISCIPLINARY SCIENCES | KINASE | GENE-EXPRESSION | REINITIATION | TRANSLATION | IDENTIFICATION | ATF6 | Amyloidogenesis | Proteins | Thapsigargin | Cell survival | Protein folding | Secretion | Transthyretin | Aging | Endoplasmic reticulum
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Coordinating Organismal Physiology Through the Unfolded Protein Response
by Wiseman, R. Luke and Haynes, Cole M
04/2018, ISBN 331978529X, 218
Proteins | Endoplasmic reticulum
eBook
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade
by Christine E. Bulawa and Stephen Connelly and Michael DeVit and Lan Wang and Charlotte Weigel and James A. Fleming and Jeff Packman and Evan T. Powers and R. Luke Wiseman and Theodore R. Foss and Ian A. Wilson and Jeffery W. Kelly and Richard Labaudinière
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2012, Volume 109, Issue 24, pp. 9629 - 9634
The transthyretin amyloidoses (ATTR) are invariably fatal diseases characterized by progressive neuropathy and/or cardiomyopathy. ATTR are caused by... 
Nervous system diseases | Teeth | Familial amyloidosis | Cardiomyopathies | Ligands | Biochemistry | Amyloids | Kinetics | Solar fibrils | Monomers | Aggregation inhibition | Drug | NEURODEGENERATIVE DISEASE | OLIGOMERIC PROTEIN | AMYLOIDOGENESIS INHIBITORS | POLYNEUROPATHY | MULTIDISCIPLINARY SCIENCES | SUBUNIT EXCHANGE | drug | PROTEIN TRANSTHYRETIN | PHYSIOLOGICAL CONDITIONS | aggregation inhibition | FIBRIL INHIBITORS | SENILE SYSTEMIC AMYLOIDOSIS | NATIVE-STATE | Amyloid - antagonists & inhibitors | Benzoxazoles - pharmacology | Prealbumin - metabolism | Humans | Models, Molecular | Binding Sites | Physiological aspects | Binding proteins | Health aspects | Proteins | Inhibitor drugs | Mutation | Medical disorders | Binding sites | Reaction kinetics | Index Medicus | Biological Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments
by Shoulders, Matthew D and Ryno, Lisa M and Genereux, Joseph C and Moresco, James J and Tu, Patricia G and Wu, Chunlei and Yates, John R and Su, Andrew I and Kelly, Jeffery W and Wiseman, R. Luke
Cell Reports, ISSN 2211-1247, 04/2013, Volume 3, Issue 4, pp. 1279 - 1292
The unfolded protein response (UPR) maintains endoplasmic reticulum (ER) proteostasis through the activation of transcription factors such as XBP1s and ATF6.... 
CELLS | UNFOLDED PROTEIN RESPONSE | LIVER-TRANSPLANTATION | DISEASE | TRANSCRIPTION | DEGRADATION | CENTRAL-NERVOUS-SYSTEM | HEREDITARY TRANSTHYRETIN AMYLOIDOSIS | ENDOPLASMIC-RETICULUM | QUALITY-CONTROL | CELL BIOLOGY | Transcription, Genetic - drug effects | Trimethoprim - pharmacology | Humans | Endoplasmic Reticulum - metabolism | Transcriptome - drug effects | Unfolded Protein Response | Regulatory Factor X Transcription Factors | Doxorubicin - toxicity | X-Box Binding Protein 1 | Hep G2 Cells | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Activating Transcription Factor 6 - metabolism | Prealbumin - metabolism | Protein Folding - drug effects | HEK293 Cells | Proteomics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Reciprocal Degradation of YME1L and OMA1 Adapts Mitochondrial Proteolytic Activity during Stress
by Rainbolt, T. Kelly and Lebeau, Justine and Puchades, Cristina and Wiseman, R. Luke
Cell Reports, ISSN 2211-1247, 03/2016, Volume 14, Issue 9, pp. 2041 - 2049
The mitochondrial inner membrane proteases YME1L and OMA1 are critical regulators of essential mitochondrial functions, including inner membrane proteostasis... 
MORPHOGENESIS | ACTIVATION | FUSION | OPA1 | PHOSPHORYLATION | PROTEASE OMA1 | FISSION | HEALTH | AUTOPHAGY | CLEAVAGE | CELL BIOLOGY | Cell Line | Mitochondria - enzymology | ATPases Associated with Diverse Cellular Activities | Proteolysis | Adenosine Triphosphate - metabolism | Humans | Membrane Potential, Mitochondrial | Metalloendopeptidases - metabolism | Mitochondrial Proteins | Peptide Hydrolases - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing
by Puchades, Cristina and Rampello, Anthony J and Shin, Mia and Giuliano, Christopher J and Wiseman, R. Luke and Glynn, Steven E and Lander, Gabriel C
Science, ISSN 0036-8075, 11/2017, Volume 358, Issue 6363, p. eaao0464
We present an atomic model of a substrate-bound inner mitochondrial membrane AAA+ quality control protease in yeast, YME1. Our ~3.4-angstrom cryo-electron... 
Phosphates | Atomic force microscopy | Residues | Yeast | Amino acids | Homology | Helices | Nucleotides | Glycine | ADP | Density | Proteins | Electron transport chain | Mitochondria | Triphosphatase | Arginine | Protease | Proteolysis | Atomic structure | Iterative methods | Protein transport | Adenosine triphosphate | Binding | Tyrosine | Biodegradation | Translocation | Peptidase | Adenosine diphosphate | Protein biosynthesis | Electron microscopy | Substrates | Membrane proteins | Hydrolysis | Transmission electron microscopy | Microscopy | Asymmetry | Quality control | Representations | Electron transport | ATP | Adenosine triphosphatase | Electrons | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis
by Blackwood, Erik A and Azizi, Khalid and Thuerauf, Donna J and Paxman, Ryan J and Paxman, Ryan J and Plate, Lars and Plate, Lars and Kelly, Jeffery W and Kelly, Jeffery W and Wiseman, R Luke and Wiseman, R. Luke and Glembotski, Christopher C
Nature communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 187 - 16
Pharmacologic activation of stress-responsive signaling pathways provides a promising approach for ameliorating imbalances in proteostasis associated with... 
ISCHEMIA/REPERFUSION INJURY | UNFOLDED PROTEIN RESPONSE | INHIBITION | ER STRESS | MULTIDISCIPLINARY SCIENCES | REPERFUSION | ISCHEMIA | DEGRADATION | MECHANISMS | EXPRESSION | STRESS SIGNALING PATHWAYS | Stresses | Cell death | Survival factor | Ribonuclease | In vitro methods and tests | Stress | Apoptosis | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Unfolded protein response activation reduces secretion and extracellular aggregation of amyloidogenic immunoglobulin light chain
by Christina B. Cooley and Lisa M. Ryno and Lars Plate and Gareth J. Morgan and John D. Hulleman and Jeffery W. Kelly and R. Luke Wiseman
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 36, pp. 13046 - 13051
Light-chain amyloidosis (AL) is a degenerative disease characterized by the extracellular aggregation of a destabilized amyloidogenic Ig light chain (LC)... 
Aggregation | Molecules | Transcription factors | Secretion | Plasma cells | Cell aggregates | Amyloidosis | Endoplasmic reticulum | Renovations | Unfolded protein response | ER proteostasis | Amyloid | SIGNALING PATHWAYS | DEXAMETHASONE | MULTIDISCIPLINARY SCIENCES | ENDOPLASMIC-RETICULUM STRESS | BORTEZOMIB | SYSTEMIC AL AMYLOIDOSIS | PROTEOSTASIS | amyloid | DISEASE | DEGRADATION | STEM-CELL TRANSPLANTATION | MELPHALAN | Unfolded Protein Response - drug effects | Luciferases - metabolism | Humans | Regulatory Factor X Transcription Factors | Amyloid - secretion | X-Box Binding Protein 1 | Immunoglobulin Light Chains - metabolism | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Proteolysis - drug effects | Activating Transcription Factor 6 - metabolism | Protein Stability - drug effects | HEK293 Cells | Extracellular Space - chemistry | Thapsigargin - pharmacology | Stress, Physiological - drug effects | Genes, Reporter | Protein Aggregates - drug effects | Protein research | Immunoglobulins | Protein folding | Amyloid beta-protein | Physiological aspects | Research | Protein-protein interactions | Proteins | Cytotoxicity | Chemotherapy | Cellular biology | Medical disorders | Index Medicus | Biological Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Prevention of Transthyretin Amyloid Disease by Changing Protein Misfolding Energetics
by Per Hammarström and R. Luke Wiseman and Evan T. Powers and Jeffery W. Kelly
Science, ISSN 0036-8075, 1/2003, Volume 299, Issue 5607, pp. 713 - 716
Genetic evidence suggests that inhibition of amyloid fibril formation by small molecules should be effective against amyloid diseases. Known amyloid inhibitors... 
Stoichiometry | Molecules | Proteostasis deficiencies | Reports | Biochemistry | Amyloids | Kinetics | Preventive medicine | Solar fibrils | Monomers | FIBRIL FORMATION | INHIBITORS | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | Amyloidosis - prevention & control | Prealbumin - genetics | Protein Subunits | Humans | Protein Folding | Prealbumin - antagonists & inhibitors | Thermodynamics | Prealbumin - metabolism | Protein Denaturation | Protein Structure, Quaternary | Prealbumin - chemistry | Amyloidosis - metabolism | Hydrogen-Ion Concentration | Suppression, Genetic | Prevention | Chemical inhibitors | Amyloidosis | Research | Proteins | Genetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text The Biological and Chemical Basis for Tissue-Selective Amyloid Disease
by Sekijima, Yoshiki and Wiseman, R. Luke and Matteson, Jeanne and Hammarström, Per and Miller, Sean R and Sawkar, Anu R and Balch, William E and Kelly, Jeffery W
Cell, ISSN 0092-8674, 2005, Volume 121, Issue 1, pp. 73 - 85
Factors controlling the onset and progression of extracellular amyloid diseases remain largely unknown. Central to disease etiology is the efficiency of the... 
FIBRIL FORMATION | LIVER-TRANSPLANTATION | SECRETION EFFICIENCY | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSTHYRETIN AMYLOIDOSIS | ENDOPLASMIC-RETICULUM | CHOROID-PLEXUS | HUMAN LYSOZYME | QUALITY-CONTROL | RNA-POLYMERASE | HUNGARIAN-TYPE | CELL BIOLOGY | Cricetinae | Molecular Chaperones - metabolism | Choroid Plexus - chemistry | Cells, Cultured | Endoplasmic Reticulum - metabolism | Organ Specificity | Protein Folding | Animals | Thyroxine - chemistry | Mice | Prealbumin - chemistry | Dimerization | Amyloidosis - metabolism | Fluorescent Antibody Technique, Indirect | Genetic research | Genetic aspects | Amyloidosis | Endoplasmic reticulum | Enzymes | Development and progression | Children | Metabolites | Diseases | Index Medicus | Naturvetenskap | Natural Sciences
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text YME1L degradation reduces mitochondrial proteolytic capacity during oxidative stress
by Rainbolt, T Kelly and Saunders, Jaclyn M and Wiseman, R Luke
EMBO reports, ISSN 1469-221X, 01/2015, Volume 16, Issue 1, pp. 97 - 106
Mitochondrial proteostasis is maintained by a network of ATP ‐dependent quality control proteases including the inner membrane protease YME 1L. Here, we show... 
protease | YME | AAA | 1L | mitochondrial proteostasis | oxidative stress | AAA protease | YME1L | COMPLEX | INNER MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | OMA1 | CLEAVAGE | CANCER | NEURODEGENERATIVE DISEASES | CELL BIOLOGY | OPA1 | MUTATIONS | DYSFUNCTION | M-AAA PROTEASE | Metalloendopeptidases - genetics | Cell Line | ATPases Associated with Diverse Cellular Activities | Oxidative Stress | Humans | Hydrogen Peroxide - pharmacology | Metalloendopeptidases - metabolism | Mitochondria - metabolism | HEK293 Cells - drug effects | Mitochondrial Proteins - metabolism | Proteolysis | Adenosine Triphosphate - metabolism | HEK293 Cells - metabolism | Intracellular Membranes - metabolism | Oxidative stress | Mitochondria | Cellular biology | Proteases | Apoptosis | Index Medicus | Scientific Reports
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation
by Plate, Lars and Cooley, Christina B and Chen, John J and Paxman, Ryan J and Gallagher, Ciara M and Madoux, Franck and Genereux, Joseph C and Dobbs, Wesley and Garza, Dan and Spicer, Timothy P and Scampavia, Louis and Brown, Steven J and Rosen, Hugh and Powers, Evan T and Walter, Peter and Hodder, Peter and Luke Wiseman, R and Kelly, Jeffery W
eLife, ISSN 2050-084X, 07/2016, Volume 5, Issue 2016
Imbalances in endoplasmic reticulum (ER) proteostasis are associated with etiologically-diverse degenerative diseases linked to excessive extracellular protein... 
XBP1 | DISEASES | STRESS-INDEPENDENT ACTIVATION | BIOLOGY | MECHANISMS | QUALITY-CONTROL | INHIBITORS | SECRETION | LESSONS | CELL-LINES | ATF6 | Activating Transcription Factor 6 - biosynthesis | Cell Line | Drug Evaluation, Preclinical - methods | Unfolded Protein Response - drug effects | Protein Aggregation, Pathological - prevention & control | Humans | Proteostasis - drug effects | Homeostasis | Physiological aspects | Extracellular matrix | Observations | Endoplasmic reticulum | Amyloidogenesis | Transcription factors | Laboratories | Secretion | Gene expression | Kinases | Proteins | Protein folding | Light | Transcription activation | Protein interaction | Research centers | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights