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Nature, ISSN 0028-0836, 12/2018, Volume 564, Issue 7736, pp. 439 - 443
Journal Article
Nature, ISSN 0028-0836, 06/2019, Volume 570, Issue 7761, pp. E53 - E53
Change history: In this Letter, author Ana Puhl was inadvertently omitted; this error has been corrected online.An amendment to this paper has been published... 
Journal Article
Organic Letters, ISSN 1523-7060, 05/2010, Volume 12, Issue 10, pp. 2270 - 2273
A novel, one-step method for the synthesis of tri- and tetrasubstituted pyrimidin-4-ones is reported. This method involves a titanium(IV)-mediated cyclization... 
CHEMISTRY, ORGANIC | DERIVATIVES | Stereoisomerism | Models, Molecular | Crystallography, X-Ray | Organometallic Compounds - chemistry | Molecular Structure | Catalysis | Pyrimidinones - chemical synthesis | Pyrimidinones - chemistry
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 2019, Volume 10, Issue 5, pp. 780 - 785
The serine/threonine protein kinase TBK1 (Tank-binding Kinase-1) is a noncanonical member of the IkB kinase (IKK) family. This kinase regulates signaling... 
kinase inhibitor | TBK1 | interferon | inflammation | CROSS-TALK | CHEMISTRY, MEDICINAL | DENDRITIC CELLS | IKK-EPSILON | PROTEIN-KINASE INHIBITORS | I INTERFERON | INNATE IMMUNITY | FAMILY
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 09/1999, Volume 5, Issue 9, pp. 2584 - 2601
A number of valuable new synthetic strategies, such as the triazene‐driven biaryl ether synthesis, have been developed during the total synthesis of vancomycin... 
Amino acids | Synthetic methods | Vancomycin | Antibiotics | Total synthesis | O-G RING | amino acids | NUCLEOPHILIC-SUBSTITUTION | BIOMIMETIC APPROACH | ARYL ETHERS | MODEL | CHEMISTRY, MULTIDISCIPLINARY | RESISTANT ENTEROCOCCI | PLAUSIBLE ACTIVE-CENTER | CROSS-COUPLING REACTIONS | RISTOCETIN-A | BIPHENYL ETHER | vancomycin | total synthesis | antibiotics | synthetic methods
Journal Article
08/2017
L'invention concerne des composés ayant la formule suivante : (la formule chimique doit être insérée ici), dans cette formule, r1, r2, r3, r4 et r5 sont tels... 
METALLURGY | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | HETEROCYCLIC COMPOUNDS | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
Angewandte Chemie International Edition, ISSN 1433-7851, 10/1998, Volume 37, Issue 19, pp. 2717 - 2719
A triazene‐based synthetic strategy for the construction of the complex biaryl ethers and a Suzuki coupling reaction were the key steps in the synthesis of... 
Amino acids | Vancomycin | Antibiotics | Natural products | Total synthesis | OXIDATION | SYSTEM | CONVERSION | amino acids | ALDEHYDES | CHEMISTRY, MULTIDISCIPLINARY | SECONDARY ALCOHOLS | natural products | 1-ARYL-3,3-DIALKYLTRIAZENES | ETHERS | ANTIBIOTIC VANCOMYCIN | PHENOLS | vancomycin | total synthesis | antibiotics
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2004, Volume 12, Issue 10, pp. 2691 - 2708
A series of bis-aryl substituted guanidines have been discovered as potent NPY Y5 antagonists. The SAR and in vitro metabolic stability of these compounds are... 
Guanidines - chemistry | Cricetinae | Animals | Cricetulus | Guanidines - chemical synthesis | Guanidines - pharmacology | Receptors, Neuropeptide Y - antagonists & inhibitors | Molecular Structure | Structure-Activity Relationship | Radioligand Assay | CHO Cells
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/1998, Volume 37, Issue 19, pp. 2714 - 2716
A triazene‐based synthetic strategy for the construction of the complex biaryl ethers and a Suzuki coupling reaction were the key steps in the synthesis of... 
Amino acids | Synthetic methods | Vancomycin | Antibiotics | Natural products | natural products | vancomycin | antibiotics | CHEMISTRY, MULTIDISCIPLINARY | synthetic methods | amino acids
Journal Article
Chemical Communications, ISSN 1359-7345, 1997, Issue 19, pp. 1899 - 1900
The effectiveness of the Suzuki coupling reaction in the formation of the AB biaryl moiety and the beneficial role of a preexisting COD ring system in a... 
OXIDATION | CHEMISTRY | K DY CHEMISTRY | MODEL | PHENOLS
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 1996, Volume 37, Issue 3, pp. 311 - 314
Three side chain analogs of didemnin B were synthesized. All three analogs of the only conventional type II β-turn present in didemnin B differed in the... 
DEPSIPEPTIDE | DYNAMICS | CHEMISTRY, ORGANIC | NMR
Journal Article
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