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Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2/2017, Volume 37, Issue 2, pp. e1 - e11
The aorta is a blood vessel that provides a low resistance path for blood flow directed from the heart to peripheral organs and tissues. However, the aorta has... 
arterial stiffness | aging | aortic compliance | pathophysiology | wall stress
Journal Article
Arteriosclerosis, thrombosis, and vascular biology, 07/2019, Volume 39, Issue 7, p. 1301
Aging has a significant impact not only on every single individual but on society as a whole. Today, people throughout the world exhibit an extended lifespan.... 
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2012, Volume 122, Issue 2, pp. 497 - 506
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2014, Volume 124, Issue 3, pp. 1083 - 1097
Genetic variation at the chromosome 9p21 risk locus promotes cardiovascular disease; however, it is unclear how or which proteins encoded at this locus... 
ENDOTHELIAL LIPASE | MEDICINE, RESEARCH & EXPERIMENTAL | SEQUENCE VARIANT | CHOLESTEROL EFFLUX | SUSCEPTIBILITY | MUSCLE-CELL APOPTOSIS | CHROMOSOME 9P21 | ABC TRANSPORTERS | CORONARY-HEART-DISEASE | EXPRESSION | MOUSE MODELS | Plaque, Atherosclerotic - genetics | Atherosclerosis - genetics | Coculture Techniques | Humans | Male | Atherosclerosis - enzymology | Plaque, Atherosclerotic - enzymology | Cyclin-Dependent Kinase Inhibitor p15 - genetics | Calreticulin - metabolism | Female | Plaque, Atherosclerotic - pathology | E2F4 Transcription Factor - metabolism | Macrophages - physiology | Atherosclerosis - pathology | Coronary Vessels - pathology | Gene Expression | Myocytes, Smooth Muscle - enzymology | Down-Regulation | Mice, Inbred C57BL | Retinoblastoma Protein - metabolism | Cells, Cultured | Mice, Knockout | E2F4 Transcription Factor - genetics | Animals | Retinoblastoma Protein - genetics | Carotid Arteries - pathology | Mice | Cyclin-Dependent Kinase Inhibitor p15 - metabolism | Quantitative Trait Loci | Necrosis - enzymology | Phagocytosis | Apoptosis | Physiological aspects | Development and progression | Enzyme inhibitors | Genetic variation | Identification and classification | Atherosclerosis | Studies | Heart attacks | Cardiovascular disease | Software | Genomes | Grants | Kinases | Laboratory animals | Gene expression | Experiments
Journal Article
Kidney International, ISSN 0085-2538, 03/2017, Volume 91, Issue 3, pp. 616 - 627
Chronic kidney disease (CKD) is associated with increased risk and worse prognosis of cardiovascular disease, including peripheral artery disease. An impaired... 
cardiovascular disease | hypoxia | chronic kidney disease | HIF-1-ALPHA/VP16 HYBRID | PROLYL HYDROXYLASE INHIBITORS | ERYTHROPOIETIN PRODUCTION | RAT REMNANT KIDNEY | ENDOTHELIAL PROGENITOR CELLS | SKELETAL-MUSCLE | ACUTE MYOCARDIAL-INFARCTION | HINDLIMB ISCHEMIA | GENE-EXPRESSION | UROLOGY & NEPHROLOGY | HEME OXYGENASE-1 | Glycine - analogs & derivatives | Neovascularization, Physiologic - drug effects | Hindlimb | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Capillaries - drug effects | Male | Ischemia - genetics | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | Renal Insufficiency, Chronic - metabolism | Isoquinolines - pharmacology | Carbon Monoxide - pharmacology | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Renal Insufficiency, Chronic - genetics | Protein Stability | Heme Oxygenase (Decyclizing) - metabolism | Capillaries - metabolism | Heme Oxygenase (Decyclizing) - genetics | Disease Models, Animal | Muscle, Skeletal - blood supply | Vascular Endothelial Growth Factor Receptor-1 - genetics | Cell Line | Capillaries - physiopathology | Human Umbilical Vein Endothelial Cells - drug effects | Gene Expression Regulation | Ischemia - metabolism | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Ischemia - physiopathology | Rats, Sprague-Dawley | Renal Insufficiency, Chronic - physiopathology | Animals | Glycine - pharmacology | Ischemia - drug therapy | Signal Transduction - drug effects
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2019, Volume 39, Issue 7, pp. 1301 - 1306
Aging has a significant impact not only on every single individual but on society as a whole. Today, people throughout the world exhibit an extended lifespan.... 
arterial stiffness | risk factors | INCREASED EXPRESSION | CARDIOVASCULAR EVENTS | OLDER-ADULTS | RISK | cardiovascular diseases | SMOOTH-MUSCLE-CELL | AORTIC STIFFNESS | DIABETES-MELLITUS | mortality | PERIPHERAL VASCULAR DISEASE | PHYSICAL-ACTIVITY | EXTRACELLULAR-MATRIX | healthy aging | morbidity | CHRONIC KIDNEY-DISEASE | HEMATOLOGY | extracellular matrix
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 11, pp. 2023 - 2023
  Vascular stiffening was accompanied by increased elastin fragmentation and collagen deposition (EvG and Picrosirius Red staining). qRT-PCR, in-situ... 
Cardiovascular | Internal Medicine | Type 2 diabetes | Studies | Rodents | Diabetes
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 10/2019, Volume 23, Issue 10, pp. 7000 - 7009
Journal Article
Circulation Research, ISSN 0009-7330, 02/2017, Volume 120, Issue 4, pp. 633 - 644
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2017, Volume 70, Issue 8, pp. 975 - 991
Takotsubo syndrome (TTS) is characterized by an acute left ventricular dysfunction and is associated with life-threating complications in the acute phase. The... 
electrical activity | broken heart syndrome | catecholamine | iPSC cardiomyocytes | lipotoxicity | TTS pathogenesis | CARDIAC & CARDIOVASCULAR SYSTEMS | TAKO-TSUBO | CARDIOMYOCYTES | ISOPROTERENOL | DEFICIENCY | PATHOGENESIS | STRESS CARDIOMYOPATHY | PATHWAY | MOUSE MODEL | ACUTE MYOCARDIAL-INFARCTION | Induced Pluripotent Stem Cells - pathology | Signal Transduction | Humans | Middle Aged | Cells, Cultured | Myocytes, Cardiac - pathology | Myocytes, Cardiac - metabolism | Adult | Female | Cell Differentiation | Receptors, Adrenergic, beta - metabolism | Takotsubo Cardiomyopathy - pathology | Catecholamines - pharmacology | Takotsubo Cardiomyopathy - metabolism | Induced Pluripotent Stem Cells - metabolism | Protein kinase A | Heart | Cardiac arrhythmia | Regulators | Phosphorylation | Heart attacks | Calcium | Toxicity | Cardiomyopathy | Pathogenesis | Ryanodine receptors | Lipids | Stimulation | Kinases | Contraction | Rodents | DNA methylation | Fibroblasts | Heart diseases | Adenosine monophosphate | Computer simulation | Cardiac muscle | Complications | Calcium channels (voltage-gated) | Muscles | Cyclic AMP | Cardiomyocytes | Metabolism | Catecholamine | Patients | Muscle contraction | Studies | Sensitivity | Adenosine kinase | Somatic cells | Stem cells | Phase (cyclic) | Adrenergic receptors | Ventricle | In vitro methods and tests | Pluripotency | Inhibitory postsynaptic potentials | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2018, Volume 38, Issue Suppl_1
Journal Article