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Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 10/2016, Volume 36, Issue 10, pp. 2035 - 2037
Journal Article
Journal Article
Journal Article
Respiratory Research, ISSN 1465-9921, 12/2011, Volume 12, Issue 1, pp. 1 - 12
Idiopathic and familial forms of pulmonary arterial hypertension (PAH) occur more frequently in women than men. However, the reason for this remains unknown.... 
Medicine & Public Health | Pneumology/Respiratory System | BREAST-CANCER | SEROTONIN TRANSPORTER | CONVERGING EVIDENCE | GENE | RESPIRATORY SYSTEM | ESTRADIOL | ESTROGEN | RATS | RECEPTOR | MONOCROTALINE | HYPOXIA | Immunohistochemistry | Up-Regulation | Cell Proliferation | Muscle, Smooth, Vascular - metabolism | Blood Pressure - genetics | S100 Calcium-Binding Protein A4 | Myocytes, Smooth Muscle - pathology | Hypertension, Pulmonary - physiopathology | Male | Pulmonary Artery - metabolism | S100 Proteins - genetics | Mice, Inbred CBA | Female | Hypertrophy, Right Ventricular - metabolism | Myocytes, Smooth Muscle - metabolism | Real-Time Polymerase Chain Reaction | Receptor for Advanced Glycation End Products | Hypertrophy, Right Ventricular - genetics | Disease Models, Animal | Estradiol - metabolism | Genetic Predisposition to Disease | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Familial Primary Pulmonary Hypertension | Hypertension, Pulmonary - genetics | Mice, Transgenic | S100 Proteins - metabolism | Hypertension, Pulmonary - metabolism | Pulmonary Artery - physiopathology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Analysis of Variance | Sex Factors | Mice | Ventricular Pressure | Receptors, Immunologic - genetics | Hypertension, Pulmonary - pathology | Pulmonary Artery - pathology | Receptors, Immunologic - metabolism | Ventricular Function, Right | Genetic aspects | Research | Demographic aspects | Calcium-binding proteins | Pulmonary hypertension | Risk factors | Heart enlargement | Physiological aspects | Sex discrimination | Gene expression | Estradiol | Protein binding | Hypertension | Proteins | Pulmonary arteries | Rodents | Veins & arteries | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2013, Volume 123, Issue 8, pp. 3600 - 3613
Dysfunctional bone morphogenetic protein receptor-2 (BMPR2) signaling is implicated in the pathogenesis of pulmonary arterial hypertension (PAH). We used a... 
MEDICINE, RESEARCH & EXPERIMENTAL | GENE | BONE MORPHOGENETIC PROTEIN | ARTERIAL-HYPERTENSION | HEART-FAILURE | IN-VIVO | APELIN | SMOOTH-MUSCLE-CELLS | TGF-BETA RECEPTOR | EXPRESSION | T-CELLS | Cell Proliferation | Humans | Microvessels - pathology | Male | Cell Hypoxia | Tacrolimus - pharmacology | Hypertension, Pulmonary - drug therapy | Endothelial Cells - physiology | Bone Morphogenetic Protein Receptors, Type II - genetics | Signal Transduction | Bone Morphogenetic Protein 4 - physiology | Endothelium, Vascular - physiopathology | Rats | Hypertension, Pulmonary - metabolism | Inhibitor of Differentiation Protein 1 - metabolism | Neointima - metabolism | Rats, Sprague-Dawley | Bone Morphogenetic Protein Receptors, Type II - metabolism | Mice, Knockout | Animals | High-Throughput Screening Assays | Neointima - drug therapy | Neointima - pathology | Tacrolimus Binding Protein 1A - metabolism | Cell Line, Tumor | Inhibitor of Differentiation Protein 1 - genetics | Endothelium, Vascular - pathology | Mice | Hypertension, Pulmonary - pathology | Smad Proteins - metabolism | Pulmonary Artery - pathology | Apoptosis | Endothelial Cells - drug effects | Hypertension | Cell receptors | Physiological aspects | Cellular signal transduction | Research | Properties | Endothelium | Proteins | Medical research | Scholarships & fellowships | Research & development--R&D | Pulmonary arteries | Rodents | Hypoxia | Ligands | Mutation | Drug dosages | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 1/2009, Volume 184, Issue 1, pp. 83 - 99
Mutations in bone morphogenetic protein (BMP) receptor II (BMPRII) are associated with pulmonary artery endothelial cell (PAEC) apoptosis and the loss of small... 
Angiogenesis | Cell motility | Receptors | Cell growth | Small interfering RNA | Antibodies | Pseudopodia | Mice | Gene expression regulation | Endothelial cells | SIGNAL-TRANSDUCTION | ACTIVATION | ARTERIAL-HYPERTENSION | II RECEPTOR | KINASE | PLANAR CELL POLARITY | P38 MAPK | C3H10T1/2 CELLS | BMPR-II | ENDOTHELIAL GROWTH-FACTOR | CELL BIOLOGY | Cell Proliferation | Humans | Glycogen Synthase Kinase 3 beta | rhoA GTP-Binding Protein - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Phosphoproteins - metabolism | Wnt Proteins - metabolism | Pulmonary Artery - metabolism | Hypertension - genetics | Dishevelled Proteins | Endothelial Cells - physiology | Bone Morphogenetic Protein Receptors, Type II - genetics | Signal Transduction | Endothelial Cells - metabolism | Glycogen Synthase Kinase 3 - metabolism | Bone Morphogenetic Protein 2 - physiology | beta Catenin - metabolism | Bone Morphogenetic Protein Receptors, Type II - metabolism | Hypertension - metabolism | Pulmonary Artery - cytology | Neovascularization, Physiologic - physiology | Pulmonary Artery - ultrastructure | Animals | Endothelial Cells - cytology | Smad1 Protein - metabolism | Wnt3 Protein | Bone Morphogenetic Protein Receptors, Type II - physiology | Enzyme Activation | Adaptor Proteins, Signal Transducing - metabolism | rac1 GTP-Binding Protein - metabolism | Apoptosis | Cell Movement | Index Medicus
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 06/2015, Volume 191, Issue 11, pp. 1273 - 1286
Journal Article
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 01/2010, Volume 298, Issue 1, pp. 23 - 35
Defective lung septation and angiogenesis, quintessential features of neonatal chronic lung disease (CLD), typically result from lengthy exposure of developing... 
Elastin | Mechanical stretch | Transforming growth factor-β | Bronchopulmonary dysplasia | Neonatal chronic lung disease | Alveolar and pulmonary capillary formation | Vascular endothelial growth factor | Lung growth and development | PHYSIOLOGY | TGF-BETA | BRONCHOPULMONARY-DYSPLASIA | PRETERM LAMBS | alveolar and pulmonary capillary formation | mechanical stretch | bronchopulmonary dysplasia | elastin | RAT LUNG | transforming growth factor-beta | EPITHELIAL-CELLS | RESPIRATORY SYSTEM | vascular endothelial growth factor | TRANSFORMING GROWTH-FACTOR-BETA-1 | neonatal chronic lung disease | NEONATAL MOUSE LUNG | SMOOTH-MUSCLE-CELLS | lung growth and development | HYALINE-MEMBRANE DISEASE | ENDOTHELIAL GROWTH-FACTOR | Cell Proliferation | Cell Count | Immunoblotting | Vascular Endothelial Growth Factor A - metabolism | Phosphoproteins - metabolism | Neovascularization, Pathologic - pathology | Time Factors | Pulmonary Alveoli - metabolism | Surface Properties | Lung - metabolism | Animals, Newborn | Elastin - metabolism | Lung - pathology | Pulmonary Alveoli - pathology | Endothelial Cells - metabolism | Smad2 Protein - metabolism | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Air | Respiration, Artificial | Animals | Models, Biological | Mice | Endothelial Cells - pathology | Lung - blood supply | Transforming Growth Factor beta - metabolism | Apoptosis | Usage | Care and treatment | Lung diseases | Physiological aspects | Research | Artificial respiration | Risk factors | Studies | Immunohistochemistry | Signal transduction | Angiogenesis | Lungs | Rodents | Ventilation | Index Medicus | transforming growth factor-β
Journal Article