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1. Full Text Brg1 promotes liver regeneration after partial hepatectomy via regulation of cell cycle
by Wang, Baocai and Kaufmann, Benedikt and Engleitner, Thomas and Lu, Miao and Mogler, Carolin and Olsavszky, Victor and Öllinger, Rupert and Zhong, Suyang and Geraud, Cyrill and Cheng, Zhangjun and Rad, Roland R and Schmid, Roland M and Friess, Helmut and Hüser, Norbert and Hartmann, Daniel and von Figura, Guido
Scientific reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 2320 - 2320
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | BRG1 protein | Sucrose | Hepatocytes | p53 Protein | Genes | Liver | Body weight | Cell cycle | Brahma-related gene | BRG1 gene | Ribonucleic acid--RNA | Index Medicus
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2. Full Text MTOR inhibitor-based combination therapies for pancreatic cancer
by Hassan, Zonera and Schneeweis, Christian and Wirth, Matthias and Veltkamp, Christian and Dantes, Zahra and Feuerecker, Benedikt and Ceyhan, Güralp O and Knauer, Shirley K and Weichert, Wilko and Schmid, Roland M and Stauber, Roland and Arlt, Alexander and Krämer, Oliver H and Rad, Roland and Reichert, Maximilian and Saur, Dieter and Schneider, Günter
British journal of cancer, ISSN 0007-0920, 02/2018, Volume 118, Issue 3, pp. 366 - 377
Life Sciences & Biomedicine | Oncology | Science & Technology | Index Medicus | Translational Therapeutics | pancreatic cancer | therapeutic resistance | MTOR
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3. Full Text Mir34a constrains pancreatic carcinogenesis
by Hidalgo-Sastre, Ana and Lubeseder-Martellato, Clara and Engleitner, Thomas and Steiger, Katja and Zhong, Suyang and Desztics, Judit and Oellinger, Rupert and Rad, Roland and Schmid, Roland M and Hermeking, Heiko and Siveke, Jens T and von Figura, Guido
Scientific reports, ISSN 2045-2322, 06/2020, Volume 10, Issue 1, pp. 9654 - 9654
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Proto-Oncogene Proteins p21(ras) - genetics | Down-Regulation | Pancreatic Neoplasms - pathology | Gene Expression Regulation, Neoplastic | Pancreatic Neoplasms - genetics | Carcinoma, Pancreatic Ductal - pathology | Carcinoma, Pancreatic Ductal - genetics | Phenotype | Animals | Sequence Analysis, RNA | High-Throughput Nucleotide Sequencing | Mice | MicroRNAs - genetics | Interleukin-6 - metabolism | Adenocarcinoma | Acinar cells | Phenotypes | p53 Protein | Inflammation | Carcinogenesis | Metastases | Interleukin 6 | MicroRNAs | miRNA | Pancreas | Tumors | Apoptosis | Index Medicus
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4. Full Text Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes
by Mueller, Sebastian and Engleitner, Thomas and Maresch, Roman and Zukowska, Magdalena and Lange, Sebastian and Kaltenbacher, Thorsten and Konukiewitz, Björn and Öllinger, Rupert and Zwiebel, Maximilian and Strong, Alex and Yen, Hsi-Yu and Banerjee, Ruby and Louzada, Sandra and Fu, Beiyuan and Seidler, Barbara and Götzfried, Juliana and Schuck, Kathleen and Hassan, Zonera and Arbeiter, Andreas and Schönhuber, Nina and Klein, Sabine and Veltkamp, Christian and Friedrich, Mathias and Rad, Lena and Barenboim, Maxim and Ziegenhain, Christoph and Hess, Julia and Dovey, Oliver M and Eser, Stefan and Parekh, Swati and Constantino-Casas, Fernando and De La Rosa, Jorge and Sierra, Marta I and Fraga, Mario and Mayerle, Julia and Klöppel, Günter and Cadiñanos, Juan and Liu, Pentao and Vassiliou, George and Weichert, Wilko and Steiger, Katja and Enard, Wolfgang and Schmid, Roland M and Yang, Fengtang and Unger, Kristian and Schneider, Günter and Varela, Ignacio and Bradley, Allan and Saur, DIeter and Rad, Roland
Nature (London), ISSN 0028-0836, 02/2018, Volume 554, Issue 7690, pp. 62 - 68
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Proto-Oncogene Proteins p21(ras) - genetics | Humans | Male | Genes, myc | Carcinoma, Pancreatic Ductal - genetics | Genes, p53 | NF-kappa B p52 Subunit - genetics | Female | Nuclear Proteins - genetics | Pancreatic Neoplasms - pathology | Carcinogenesis - genetics | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Pancreatic Neoplasms - genetics | Gene Dosage | Transcriptome - genetics | Transforming Growth Factor beta1 - genetics | Phosphoproteins - genetics | Transcription Factors - genetics | Carcinoma, Pancreatic Ductal - pathology | Disease Progression | Neoplasm Metastasis - genetics | Phenotype | Animals | Adaptor Proteins, Signal Transducing - genetics | Alleles | Mice | Mutation | Cell Cycle Proteins | Evolution, Molecular | Biological research | Cell culture | Pancreatic cancer | Physiological aspects | Genetic aspects | Research | Biology, Experimental | Adenocarcinoma | Gene dosage | Pathogenesis | Genomics | Genes | Cytology | Genomes | Metastasis | Myc protein | Cell morphology | Metastases | Studies | Yes-associated protein | Genotype & phenotype | Histopathology | Evolution | Tumorigenesis | Chromosomes | Tumors | Index Medicus
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5. Full Text Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon
by Rad, Roland and Yusa, Kosuke and Bradley, Allan and Takeda, Junji
Nature methods, ISSN 1548-7091, 05/2009, Volume 6, Issue 5, pp. 363 - 369
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | RNA-Binding Proteins - genetics | Gene Expression - genetics | Homeodomain Proteins - metabolism | Humans | Alkaline Phosphatase - metabolism | Valproic Acid - pharmacology | Embryo, Mammalian - metabolism | SOXB1 Transcription Factors - metabolism | Moths - genetics | Octamer Transcription Factor-3 - genetics | Chimera - embryology | Transfection | SOXB1 Transcription Factors - genetics | Kruppel-Like Transcription Factors - metabolism | Transposases - genetics | DNA Transposable Elements - genetics | Transgenes | Cell Differentiation - physiology | Nanog Homeobox Protein | Pluripotent Stem Cells - cytology | Cell Dedifferentiation - drug effects | Repressor Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Genetic Vectors - genetics | Pluripotent Stem Cells - metabolism | Teratoma - pathology | Animals | Embryo, Mammalian - cytology | Fibroblasts - drug effects | Octamer Transcription Factor-3 - metabolism | Pluripotent Stem Cells - transplantation | Fibroblasts - cytology | Mice | Proto-Oncogene Proteins c-myc - genetics | Cell Dedifferentiation - genetics | Chimera - metabolism | Kruppel-Like Transcription Factors - genetics | RNA-Binding Proteins - metabolism | Physiological aspects | Transposons | Nuclear reprogramming | Research | Gene expression | Genetic engineering | Rodents | Research methodology | Stem cells | Index Medicus
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6. Full Text Interstitial cells of Cajal integrate excitatory and inhibitory neurotransmission with intestinal slow-wave activity
by Klein, Sabine and Seidler, Barbara and Kettenberger, Anna and Sibaev, Andrei and Rohn, Michael and Feil, Robert and Allescher, Hans-Dieter and Vanderwinden, Jean-Marie and Hofmann, Franz and Schemann, Michael and Rad, Roland and Storr, Martin A and Schmid, Roland M and Schneider, Günter and Saur, Dieter
Nature communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 1630 - 1630
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Animals | Interstitial Cells of Cajal - physiology | Cells, Cultured | Cyclic GMP-Dependent Protein Kinase Type I - genetics | Mice, Transgenic | Mice | Enteric Nervous System - physiology | Synaptic Transmission | Index Medicus
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7. Full Text Engineering CRISPR mouse models of cancer
by Weber, Julia and Rad, Roland
Current opinion in genetics & development, ISSN 0959-437X, 02/2019, Volume 54, pp. 88 - 96
Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryonic Stem Cells - metabolism | Genetic Therapy | Germ Cells - transplantation | Humans | CRISPR-Cas Systems - genetics | Gene Editing | Animals | Genetic Engineering | Epigenome - genetics | Neoplasms - genetics | Mice | Germ Cells - metabolism | Mutation | Neoplasms - pathology | Disease Models, Animal | Index Medicus
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8. Full Text Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice
by Maresch, Roman and Mueller, Sebastian and Veltkamp, Christian and Öllinger, Rupert and Friedrich, Mathias and Heid, Irina and Steiger, Katja and Weber, Julia and Engleitner, Thomas and Barenboim, Maxim and Klein, Sabine and Louzada, Sandra and Banerjee, Ruby and Strong, Alexander and Stauber, Teresa and Gross, Nina and Geumann, Ulf and Lange, Sebastian and Ringelhan, Marc and Varela, Ignacio and Unger, Kristian and Yang, Fengtang and Schmid, Roland M and Vassiliou, George S and Braren, Rickmer and Schneider, Günter and Heikenwalder, Mathias and Bradley, Allan and Saur, Dieter and Rad, Roland
Nature communications, ISSN 2041-1723, 02/2016, Volume 7, Issue 1, pp. 10770 - 10770
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Chromosome Deletion | Genetic Engineering - methods | Immunohistochemistry | Proto-Oncogene Proteins p21(ras) - genetics | Carcinogenesis - genetics | Electroporation | Pancreatic Neoplasms - genetics | Pancreas - metabolism | Phylogeny | Sequence Analysis, DNA | Magnetic Resonance Imaging | Animals | Transfection - methods | CRISPR-Cas Systems | Neoplasms, Experimental - genetics | Polymerase Chain Reaction | High-Throughput Nucleotide Sequencing | Mice | Mutation | Genome | BRCA2 Protein - genetics | Translocation, Genetic - genetics | Index Medicus
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9. Full Text A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer
by Rad, Roland and Rad, Roland and Rad, Lena and Rad, Lena and Wang, Wei and Wang, Wei and Strong, Alexander and Strong, Alexander and Ponstingl, Hannes and Ponstingl, Hannes and Bronner, Iraad F and Bronner, Iraad F and Mayho, Matthew and Mayho, Matthew and Steiger, Katja and Steiger, Katja and Weber, Julia and Weber, Julia and Hieber, Maren and Hieber, Maren and Veltkamp, Christian and Veltkamp, Christian and Eser, Stefan and Eser, Stefan and Geumann, Ulf and Geumann, Ulf and Öllinger, Rupert and Öllinger, Rupert and Zukowska, Magdalena and Zukowska, Magdalena and Barenboim, Maxim and Barenboim, Maxim and Maresch, Roman and Maresch, Roman and Cadiñanos, Juan and Cadiñanos, Juan and Friedrich, Mathias and Friedrich, Mathias and Varela, Ignacio and Varela, Ignacio and Constantino-Casas, Fernando and Constantino-Casas, Fernando and Sarver, Aaron and Sarver, Aaron and Ten Hoeve, Jelle and Ten Hoeve, Jelle and Prosser, Haydn and Prosser, Haydn and Seidler, Barbara and Seidler, Barbara and Bauer, Judith and Bauer, Judith and Heikenwälder, Mathias and Heikenwälder, Mathias and Metzakopian, Emmanouil and Metzakopian, Emmanouil and Krug, Anne and Krug, Anne and Ehmer, Ursula and Ehmer, Ursula and Schneider, Gönter and Schneider, Günter and Knösel, Thomas and Knösel, Thomas and Römmele, Petra and Rümmele, Petra and Aust, Daniela and Aust, Daniela and Grützmann, Robert and Grötzmann, Robert and Pilarsky, Christian and Pilarsky, Christian and Ning, Zemin and Ning, Zemin and Wessels, Lodewyk and Wessels, Lodewyk and M Schmid, Roland and Schmid, Roland M and A Quail, Michael and Quail, Michael A and Vassiliou, George and Vassiliou, George and Esposito, Irene and Esposito, Irene and Liu, Pentao and Liu, Pentao and Saur, Dieter and Saur, Dieter and Bradley, Allan and Bradley, Allan