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Journal of Clinical Investigation, ISSN 0021-9738, 10/2015, Volume 125, Issue 10, pp. 3766 - 3781
The development of inhibitory antibodies to factor VIII (FVIII) is a major obstacle in using this clotting factor to treat individuals with hemophilia A.... 
MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNE-RESPONSE | DENDRITIC CELLS | TOLERANCE INDUCTION | ARYL-HYDROCARBON RECEPTOR | INDOLEAMINE 2,3-DIOXYGENASE IDO | REGULATORY T-CELLS | GENE-THERAPY | KAPPA-B | TRYPTOPHAN CATABOLISM | CUTTING EDGE | Factor VIII - immunology | Oligodeoxyribonucleotides - administration & dosage | Isoantibodies - biosynthesis | Humans | Male | NF-kappa B - metabolism | Toll-Like Receptor 9 - physiology | Molecular Targeted Therapy | Tryptophan - metabolism | Case-Control Studies | Toll-Like Receptor 9 - agonists | T-Lymphocytes, Regulatory - immunology | Enzyme Induction - drug effects | Models, Animal | Cytokines - blood | Factor VIII - therapeutic use | Oligodeoxyribonucleotides - therapeutic use | Indoleamine-Pyrrole 2,3,-Dioxygenase - blood | Drug Administration Schedule | Hemophilia A - immunology | Mice, Inbred C57BL | Immune Tolerance | Mice, Knockout | Animals | Dendritic Cells - enzymology | Isoantibodies - immunology | Leukocytes, Mononuclear - enzymology | Mice | Hemophilia A - drug therapy | Indoleamine-Pyrrole 2,3,-Dioxygenase - physiology | T-Lymphocytes, Regulatory - enzymology | Plasma Cells - immunology | Enzymes | Care and treatment | Usage | Blood coagulation factor VIII | Health aspects | Hemophilia | Proteins | Immunoglobulins | Hypotheses | Mortality | Values | Mutation | Experiments | Patients | Logistics
Journal Article
Cell and Tissue Research, ISSN 0302-766X, 10/2016, Volume 366, Issue 1, pp. 51 - 61
Journal Article
European Journal of Haematology, ISSN 0902-4441, 10/2019, Volume 103, Issue 4, pp. 379 - 384
Objectives Inherited dysfibrinogenemia is a rare disorder, for which clinical studies related to the risk of bleeding or thrombosis and the type of causative... 
thrombophilia | dysfibrinogenemia | inherited bleeding disorders | fibrinogen | gene mutation | Pregnancy | Ischemia | Fibrinogen | Mutation | Thromboembolism | Health risk assessment | Thrombosis | Bleeding
Journal Article
Journal of thrombosis and haemostasis : JTH, ISSN 1538-7933, 11/2019
Careful assessment of bleeding history is the first step in the evaluation of patients with mild/moderate bleeding disorders, and the use of a bleeding... 
Journal Article
Blood transfusion = Trasfusione del sangue, ISSN 1723-2007, 01/2019, Volume 17, Issue 1, pp. 72 - 82
Background. Since 2001, we have used conformation sensitive gel electrophoresis (CSGE) as our first choice for F9 gene mutation screening, leading to the... 
Haemophilia | Gene mutations | High-resolution melting | Genetic counselling | genetic counselling | VARIANTS | DATABASE | high-resolution melting | SEQUENCE | haemophilia | gene mutations | FACTOR-IX GENE | IDENTIFICATION | HEMATOLOGY | Original
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2015, Volume 125, Issue 10, pp. 3766 - 3766
The development of inhibitory antibodies to factor VIII (FVIII) is a major obstacle in using this clotting factor to treat individuals with hemophilia A.... 
Journal Article
by Santagostino, Elena and Riva, Agostino and Cesaro, Simone and Esposito, Susanna and Matino, Davide and Mazzucchelli, Renata Ilde and Molinari, Angelo Claudio and Mura, Rosamaria and Notarangelo, Lucia Dora and Tagliaferri, Annarita and Di Minno, Giovanni and Clerici, Mario and Ambaglio, Chiara and Brigida Aru, Anna and Baldacci, Erminia and Barillari, Giovanni and Basso, Maria and Bernasconi, Sayla and Bertamino, Marta and Bertoni, Elisa and Biasoli, Chiara and Federica Biguzzi, Eugenia and Bonetti, Elisa and Borchiellini, Alessandra and Bulgarelli, Simona and Cabibbo, Sergio and Cantori, Isabella and Castaman, Giancarlo and Castiglia, Paolo and Coluccia, Antonella and Coppetelli, Ugo and Coppola, Antonio and Cultrera, Dorina and De Candia, Erica and Delios, Grazia and Di Gennaro, Leonardo and Di Gregorio, Patrizia and Di Minno, Matteo and Dragani, Alfredo and Pietro Ettorre, Cosimo and Franchini, Massimo and Galli, Massimo and Gallo, Giovanni and Giordano, Paola and Giuffrida, Gaetano and Iannaccaro, Piergiorgio and Lassandro, Giuseppe and Lazzareschi, Ilaria and Linari, Silvia and Luciani, Matteo and Macchi, Silvia and Malcangi, Giuseppe and Malizia, Raniero and Marietta, Marco and Marino, Renato and Massoud, Michela and Gabriella Mazzucconi, Maria and Milan, Marta and Morfini, Massimo and Napolitano, Mariasanta and Pasca, Samantha and Pedrazzi, Paola and Peyvandi, Flora A and Piscitelli, Lydia and Pollio, Berardino and Preti, Paola and Quintavalle, Gabriele and Radossi, Paolo and Raso, Simona and Ricca, Irene and Rocino, Angiola and Santoro, Cristina and Carlotta Santoro, Rita and Sarolo, Lucia and Schiavoni, Mario and Schiavulli, Michele and Sciancalepore, Patrizia and Luisa Serino, Maria and Mario Siragusa, Sergio and Sottilotta, Gianluca and Svahn, Johanna and Valdrè, Lelia and Cristina Vedovati, Maria and Zanon, Ezio and HEVA Study Grp and the HEVA Study Group
Haemophilia, ISSN 1351-8216, 07/2019, Volume 25, Issue 4, pp. 656 - 667
Journal Article
Journal Article
by Franchini, Massimo and Castaman, Giancarlo and Coppola, Antonio and Santoro, Cristina and Zanon, Ezio and Di Minno, Giovanni and Morfini, Massimo and Santagostino, Elena and Rocino, Angiola and Abbate, Rosanna and Aru, Anna Brigida and Biasoli, Chiara and Borchiellini, Alessandra and Caimi, Teresa Maria and Cantori, Isabella and Cerbone, Anna Maria and Cesaro, Simone and Ciabatta, Carlo and Coluccia, Antonella and Contino, Laura and Cultrera, Dorina and De Cristofaro, Raimondo and Delios, Grazia and Di Minno, Matteo Nicola Dario and Dragani, Alfredo and Ettorre, Cosimo Pietro and Feola, Giulio and Gamba, Gabriella and Gandini, Giorgio and Giuffrida, Anna Chiara and Giuffrida, Gaetano and Gresele, Paolo and Hassan, Hamisa Jane and Lassandro, Giuseppe and Latella, Caterina and Linari, Silvia and Luciani, Matteo and Mancuso, Maria Elisa and Marchesini, Emanuela and Marino, Renato and Matino, Davide and Mazzucconi, Maria Gabriella and Messina, Maria and Milan, Marta and Molinari, Angelo Claudio and Napolitano, Mariasanta and Notarangelo, Lucia Dora and Peyvandi, Flora and Pollio, Berardino and Radossi, Paolo and Riccardi, Federica and Riva, Silvia and Rivolta, Gianna Franca and Rossetti, Gina and Santoro, Rita Carlotta and Serino, Maria Luisa and Schiavulli, Michele and Schiavoni, Mario and Schinco, Piercarla and Solimeno, Luigi Piero and Sottilotta, Gianluca and Targhetta, Roberto and Tagliaferri, Annarita and Testa, Sophie and Todisco, Angela and Turello, Marina and Valdrè, Lelia and AICE Working Grp and AICE Working Group
Blood Transfusion, ISSN 1723-2007, 07/2015, Volume 13, Issue 3, pp. 498 - 513
Journal Article
British Journal of Haematology, ISSN 0007-1048, 04/2012, Volume 157, Issue 2, pp. 256 - 258
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 2818 - 2818
Abstract Introduction: The efficacy of factor VIII and IX concentrates administered to prevent bleeding episodes in patients with hemophilia A and B is... 
Journal Article
Haemophilia, ISSN 1351-8216, 09/2018, Volume 24, Issue 5, pp. 766 - 773
Journal Article