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by Sudmant, Peter H and Rausch, Tobias and Gardner, Eugene J and Handsaker, Robert E and Abyzov, Alexej and Huddleston, John and Zhang, Yan and Ye, Kai and Jun, Goo and Hsi-Yang Fritz, Markus and Konkel, Miriam K and Malhotra, Ankit and Stütz, Adrian M and Shi, Xinghua and Paolo Casale, Francesco and Chen, Jieming and Hormozdiari, Fereydoun and Dayama, Gargi and Chen, Ken and Malig, Maika and Chaisson, Mark J. P and Walter, Klaudia and Meiers, Sascha and Kashin, Seva and Garrison, Erik and Auton, Adam and Lam, Hugo Y. K and Jasmine Mu, Xinmeng and Alkan, Can and Antaki, Danny and Bae, Taejeong and Cerveira, Eliza and Chines, Peter and Chong, Zechen and Clarke, Laura and Dal, Elif and Ding, Li and Emery, Sarah and Fan, Xian and Gujral, Madhusudan and Kahveci, Fatma and Kidd, Jeffrey M and Kong, Yu and Lameijer, Eric-Wubbo and McCarthy, Shane and Flicek, Paul and Gibbs, Richard A and Marth, Gabor and Mason, Christopher E and Menelaou, Androniki and Muzny, Donna M and Nelson, Bradley J and Noor, Amina and Parrish, Nicholas F and Pendleton, Matthew and Quitadamo, Andrew and Raeder, Benjamin and Schadt, Eric E and Romanovitch, Mallory and Schlattl, Andreas and Sebra, Robert and Shabalin, Andrey A and Untergasser, Andreas and Walker, Jerilyn A and Wang, Min and Yu, Fuli and Zhang, Chengsheng and Zhang, Jing and Zheng-Bradley, Xiangqun and Zhou, Wanding and Zichner, Thomas and Sebat, Jonathan and Batzer, Mark A and McCarroll, Steven A and Mills, Ryan E and Gerstein, Mark B and Bashir, Ali and Stegle, Oliver and Devine, Scott E and Lee, Charles and Eichler, Evan E and Korbel, Jan O and The 1000 Genomes Project Consortium and Genomes Project Consortium and 1000 Genomes Project Consortium
Nature (London), ISSN 1476-4687, 09/2015, Volume 526, Issue 7571, pp. 75 - 81
Journal Article
by Jones, David T W and Hutter, Barbara and Jäger, Natalie and Korshunov, Andrey and Kool, Marcel and Warnatz, Hans-Jörg and Zichner, Thomas and Lambert, Sally R and Ryzhova, Marina and Quang, Dong Anh Khuong and Fontebasso, Adam M and Stütz, Adrian M and Hutter, Sonja and Zuckermann, Marc and Sturm, Dominik and Gronych, Jan and Lasitschka, Bärbel and Schmidt, Sabine and Şeker-Cin, Huriye and Witt, Hendrik and Sultan, Marc and Ralser, Meryem and Northcott, Paul A and Hovestadt, Volker and Bender, Sebastian and Pfaff, Elke and Stark, Sebastian and Faury, Damien and Schwartzentruber, Jeremy and Majewski, Jacek and Weber, Ursula D and Zapatka, Marc and Raeder, Benjamin and Schlesner, Matthias and Worth, Catherine L and Bartholomae, Cynthia C and von Kalle, Christof and Imbusch, Charles D and Radomski, Sylwester and Lawerenz, Chris and van Sluis, Peter and Koster, Jan and Volckmann, Richard and Versteeg, Rogier and Lehrach, Hans and Monoranu, Camelia and Winkler, Beate and Unterberg, Andreas and Herold-Mende, Christel and Milde, Till and Kulozik, Andreas E and Ebinger, Martin and Schuhmann, Martin U and Cho, Yoon-Jae and Pomeroy, Scott L and von Deimling, Andreas and Witt, Olaf and Taylor, Michael D and Wolf, Stephan and Karajannis, Matthias A and Eberhart, Charles G and Scheurlen, Wolfram and Hasselblatt, Martin and Ligon, Keith L and Kieran, Mark W and Korbel, Jan O and Yaspo, Marie-Laure and Brors, Benedikt and Felsberg, Jörg and Reifenberger, Guido and Collins, V Peter and Jabado, Nada and Eils, Roland and Lichter, Peter and the International Cancer Genome Consortium PedBrain Tumor Project and Int Canc Genome Consortium and International Cancer Genome Consortium PedBrain Tumor Project
Nature genetics, ISSN 1546-1718, 06/2013, Volume 45, Issue 8, pp. 927 - 932
Journal Article
Journal Article
by Northcott, Paul A and Lee, Catherine and Zichner, Thomas and Stütz, Adrian M and Erkek, Serap and Kawauchi, Daisuke and Shih, David J. H and Hovestadt, Volker and Zapatka, Marc and Sturm, Dominik and Jones, David T. W and Kool, Marcel and Remke, Marc and Cavalli, Florence M. G and Zuyderduyn, Scott and Bader, Gary D and VandenBerg, Scott and Esparza, Lourdes Adriana and Ryzhova, Marina and Wang, Wei and Wittmann, Andrea and Stark, Sebastian and Sieber, Laura and Seker-Cin, Huriye and Linke, Linda and Kratochwil, Fabian and Jäger, Natalie and Buchhalter, Ivo and Imbusch, Charles D and Zipprich, Gideon and Raeder, Benjamin and Schmidt, Sabine and Diessl, Nicolle and Wolf, Stephan and Wiemann, Stefan and Brors, Benedikt and Lawerenz, Chris and Eils, Jürgen and Warnatz, Hans-Jörg and Risch, Thomas and Yaspo, Marie-Laure and Weber, Ursula D and Bartholomae, Cynthia C and von Kalle, Christof and Turányi, Eszter and Hauser, Peter and Sanden, Emma and Darabi, Anna and Siesjö, Peter and Sterba, Jaroslav and Zitterbart, Karel and Sumerauer, David and van Sluis, Peter and Versteeg, Rogier and Volckmann, Richard and Koster, Jan and Schuhmann, Martin U and Ebinger, Martin and Grimes, H. Leighton and Robinson, Giles W and Gajjar, Amar and Mynarek, Martin and von Hoff, Katja and Rutkowski, Stefan and Pietsch, Torsten and Scheurlen, Wolfram and Felsberg, Jörg and Reifenberger, Guido and Kulozik, Andreas E and von Deimling, Andreas and Witt, Olaf and Eils, Roland and Gilbertson, Richard J and Korshunov, Andrey and Taylor, Michael D and Lichter, Peter and Korbel, Jan O and Wechsler-Reya, Robert J and Pfister, Stefan M
Nature (London), ISSN 1476-4687, 06/2014, Volume 511, Issue 7510, pp. 428 - 434
Journal Article
Nature genetics, ISSN 1546-1718, 07/2015, Volume 47, Issue 9, pp. 1020 - 1029
TCF3-HLF-positive acute lymphoblastic leukemia (ALL) is currently incurable. Using an integrated approach, we uncovered distinct mutation, gene expression and... 
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Sequence Deletion | Oncogene Proteins, Fusion - metabolism | Coculture Techniques | Genomics | Humans | Drug Resistance, Neoplasm | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - mortality | Antineoplastic Agents - therapeutic use | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | DNA Mutational Analysis | Inhibitory Concentration 50 | Female | Antineoplastic Agents - pharmacology | Immunoglobulin Light Chains, Surrogate - genetics | Gene Expression | Genetic Association Studies | Kaplan-Meier Estimate | PAX5 Transcription Factor - genetics | Mice, SCID | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Xenograft Model Antitumor Assays | Animals | Oncogene Proteins, Fusion - genetics | Mice, Inbred NOD | Mutation | Cohort Studies | Gene mutations | Genetic aspects | Acute lymphocytic leukemia | Research | Identification and classification | Health aspects | Risk factors | Bone marrow | Genes | Leukemia | Index Medicus | cytarabine | integrative | leukemic stem cell | drug activity profiling | panobinostat | mTOR inhibitor | genomics | glucocorticoids | bortezomib | ABT-199 | dexamethasone | HSP90 | TCF3-PBX1 | vincristine | BH3-mimetics | leukemia xenograft model | next generation sequencing | TCF3-HLF | venetoclax | anthracycline | acute lymphoblastic leukemia | AUY922 | BCL2 | drug resistance | prednisone
Journal Article