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1. Full Text Focus on Early Events: Pathogenesis of Pulmonary Arterial Hypertension Development
by Rafikova, Olga and Al Ghouleh, Imad and Rafikov, Ruslan
Antioxidants & redox signaling, ISSN 1523-0864, 11/2019, Volume 31, Issue 13, pp. 933 - 953
Forum Original Review Articles | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Hypertension | Pathogenesis | Lung diseases | Muscles | Smooth muscle | Survival | Complex systems | Patients | Pulmonary hypertension | Complexity | Pathways | Fibroblasts | Diagnosis | Heart diseases | Index Medicus | inflammation | pulmonary hypertension | Forum Original Review | metabolism | vascular damage | hemolysis | oxidative stress
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2. Full Text eNOS activation and NO function: Structural motifs responsible for the posttranslational control of endothelial nitric oxide synthase activity
by Rafikov, Ruslan and Fonseca, Fabio V and Kumar, Sanjiv and Pardo, Daniel and Darragh, Charles and Elms, Shawn and Fulton, David and Black, Stephen M
Journal of endocrinology, ISSN 0022-0795, 9/2011, Volume 210, Issue 3, pp. 271 - 284
Thematic Review | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Amino Acid Sequence | Phosphorylation | Humans | Models, Molecular | Molecular Sequence Data | Threonine - metabolism | Biopterin - analogs & derivatives | Serine - metabolism | Molecular Dynamics Simulation | Biopterin - metabolism | Nitric Oxide Synthase Type III - chemistry | Tyrosine - metabolism | Animals | Protein Structure, Quaternary | Cell Membrane - metabolism | Protein Processing, Post-Translational | Enzyme Activation | Nitric Oxide Synthase Type III - metabolism | Nitric Oxide - metabolism | Dimerization | Index Medicus
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3. Full Text Recurrent inhibition of mitochondrial complex III induces chronic pulmonary vasoconstriction and glycolytic switch in the rat lung
by Rafikova, Olga and Srivastava, Anup and Desai, Ankit A and Rafikov, Ruslan and Tofovic, Stevan P
Respiratory research, ISSN 1465-9921, 04/2018, Volume 19, Issue 1, pp. 69 - 69
Metabolomics | Glycolytic switch | Mitochondrial complexes | Protein nitration | Pulmonary hypertension | Life Sciences & Biomedicine | Respiratory System | Science & Technology | Glucose metabolism | Analysis | Rattus | Vasoconstriction | Rats | Physiological aspects | Development and progression | Mitochondrial diseases | Succinate dehydrogenase complex | Genetic aspects | Health aspects | Index Medicus | Research
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4. Full Text Heme-Driven ROS Production Leads to Increased P38 MAP Kinase Activity and Endothelial Barrier Disruption
by Reavis, Daniel and Zemskov, Evgeny and Rafikov, Ruslan
Free radical biology & medicine, ISSN 0891-5849, 11/2016, Volume 100, pp. S149 - S150
Antioxidants | Heme | Cellular signal transduction | Permeability | Mitogens | Protein kinases | Endothelium
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5. Full Text Pulmonary hypertension in rats with human mutation of NFU1 is oxygen sensitive
by Niihori, Maki and Eccles, Cody and Zemskova, Marina and Rafikov, Ruslan and Rafikova, Olga
Free radical biology & medicine, ISSN 0891-5849, 11/2018, Volume 128, p. S34
Proteins | Genetic research | Genetic aspects | Pulmonary hypertension
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6. Hemolysis-induced lung vascular leakage contributes to the development of pulmonary hypertension
by Rafikova, Olga and Williams, Elissa R and McBride, Matthew L and Zemskova, Marina and Srivastava, Anup and Nair, Vineet and Desai, Ankit A and Langlais, Paul R and Zemskov, Evgeny and Simon, Marc and Mandarino, Lawrence J and Rafikov, Ruslan
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 09/2018, Volume 59, Issue 3, pp. 334 - 345
Hemoglobin | Edema | Pulmonary arterial hypertension | Endothelial barrier | Heme | Respiratory System | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Kinases | Proteins | Signal transduction | Hypoxia-inducible factor 1a | Hemolytic anemia | Haptoglobin | Rodents | Sickle cell disease | Hypertension | Hemolysis | Catheterization | Review boards | Anemia | Heme oxygenase (decyclizing) | Inflammation | Permeability | Gene expression | Endothelial cells | Pulmonary hypertension | Human subjects | Oxygenase | Lungs | Hsp27 protein | Nitric oxide | Sepsis | Hypoxia | Microvasculature | Intubation
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7. Full Text Gender Difference in Damage-Mediated Signaling Contributes to Pulmonary Arterial Hypertension
by Rafikov, Ruslan and Nair, Vineet and Sinari, Shripad and Babu, Harini and Sullivan, Jennifer C and Yuan, Jason X.-J and Desai, Ankit A and Rafikova, Olga
Antioxidants & redox signaling, ISSN 1523-0864, 11/2019, Volume 31, Issue 13, pp. 917 - 932
Forum Original Research Communication | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Phosphorylation | Animal models | Pathogenesis | Interleukin | Homeostasis | Activation | Dimorphism | Gender | Leukocytes | Males | HMGB1 protein | Arteries | Necrosis | Signal transduction | Pathways | Interleukin 1 | Toll-like receptors | Damage | Hypertension | Brain natriuretic peptide | Pulmonary arteries | Markers | Sex differences | Inflammation | TLR4 protein | Pulmonary artery | Endothelial cells | Pulmonary hypertension | E-selectin | Signaling | Cell death | Apoptosis | Index Medicus | gender difference | necrosis | inflammation | pulmonary hypertension
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8. Full Text Targeted Protein Protection from Oxidative/ Nitrosative Post-Translational Modifications Using Shielding Peptides
by Rafikova, Olga and Black, Stephen M and Rafikov, Ruslan
Free radical biology & medicine, ISSN 0891-5849, 10/2015, Volume 87, p. S94
Peptides
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9. Full Text Bio-Catalysis of Heme Extraction from Extracellular Hemoglobin for Sickle Cell Disease and Hemolysis Treatment
by Sakipov, Serzhan and Kurnikova, Maria and Rafikov, Ruslan
Free radical biology & medicine, ISSN 0891-5849, 10/2015, Volume 87, p. S56
Hemoglobin | Sickle cell anemia | Catalysis | Drug therapy | Heme
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10. Rats with a Human Mutation of NFU1 Develop Pulmonary Hypertension
by Niihori, Maki and Eccles, Cody A and Kurdyukov, Sergey and Zemskova, Marina and Varghese, Mathews Valuparampil and Stepanova, Anna A and Galkin, Alexander and Rafikov, Ruslan and Rafikova, Olga
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 02/2020, Volume 62, Issue 2, pp. 231 - 242
Respiratory System | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Humans | Rats | Hypertension, Pulmonary - genetics | Hypertension, Pulmonary - metabolism | Mitochondria - metabolism | Mitochondrial Proteins - genetics | Mutation - genetics | Carrier Proteins - genetics | Phenotype | Animals | Mitochondrial Proteins - metabolism | Hypertrophy, Right Ventricular - metabolism | Hypertrophy, Right Ventricular - genetics | Proteins | Hypertension | Mitochondria | Energy metabolism | Rodents | Heredity | Mutation | Sulfur | Electron transport | Pulmonary hypertension
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11. Full Text Necrosis-Released HMGB1 (High Mobility Group Box 1) in the Progressive Pulmonary Arterial Hypertension Associated With Male Sex
by Zemskova, Marina and McClain, Nolan and Niihori, Maki and Varghese, Mathews V and James, Joel and Rafikov, Ruslan and Rafikova, Olga
Hypertension (Dallas, Tex. 1979), ISSN 0194-911X, 12/2020, Volume 76, Issue 6, pp. 1787 - 1799
Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Chromosomal proteins | Cell death | Pulmonary hypertension | Necrosis | Index Medicus
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12. Full Text Heme induces rapid endothelial barrier dysfunction via the MKK3/p38MAPK axis
by James, Joel and Srivastava, Anup and Varghese, Mathews Valuparampil and Eccles, Cody A and Zemskova, Marina and Rafikova, Olga and Rafikov, Ruslan
Blood, ISSN 0006-4971, 08/2020, Volume 136, Issue 6, pp. 749 - 754
Index Medicus | Abridged Index Medicus | Brief Report | 36 | 38 | 6 | Vascular Biology
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13. Activation of calpain-2 by mediators in pulmonary vascular remodeling of pulmonary arterial hypertension
by Kovacs, Laszlo and Han, Weihong and Rafikov, Ruslan and Bagi, Zsolt and Offermanns, Stefan and Saido, Takaomi C and Black, Stephen M and Su, Yunchao
American journal of respiratory cell and molecular biology, ISSN 1044-1549, 03/2016, Volume 54, Issue 3, pp. 384 - 393
Platelet-derived growth factor | Serotonin | Pulmonary hypertension | Vascular smooth muscle cells | Respiratory System | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Enzyme Activators - pharmacology | Phosphorylation | Calpain - metabolism | Humans | Myocytes, Smooth Muscle - pathology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Hypertension, Pulmonary - physiopathology | Extracellular Signal-Regulated MAP Kinases - metabolism | Calpain - genetics | Muscle, Smooth, Vascular - physiopathology | Transfection | RNA Interference | HEK293 Cells | Vascular Remodeling - drug effects | Myocytes, Smooth Muscle - drug effects | Hypertension, Pulmonary - enzymology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Calcium-Binding Proteins - metabolism | Protein Phosphatase 2 - antagonists & inhibitors | Signal Transduction | Myocytes, Smooth Muscle - enzymology | Hypertension, Pulmonary - genetics | Hypoxia - complications | Pulmonary Artery - physiopathology | Pulmonary Artery - drug effects | Pulmonary Artery - enzymology | Mice, Knockout | Muscle, Smooth, Vascular - pathology | Animals | Protein Phosphatase 2 - metabolism | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Hypertension, Pulmonary - pathology | Muscle, Smooth, Vascular - enzymology | Pulmonary Artery - pathology | Calcium-Binding Proteins - genetics | Immunoglobulins | Cytokines | Pulmonary arteries | Smooth muscle | Kinases | Gene expression | Phosphatase | Proteins | Rodents | Sheep | Hypoxia | Extracellular matrix | Scientific imaging | Growth factors | Veins & arteries | Index Medicus
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