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plant sciences (5) 5
gene expression (4) 4
plant proteins - genetics (4) 4
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分子植物:英文版, ISSN 1674-2052, 2013, Volume 6, Issue 5, pp. 1531 - 1549
... Synthases frOm Catharanthus roseus a n d Th e i r Ro l e i n M O n Ote rpe n e I n d o l e Al ka loid B iosynthesis Avanish Rai。,Shachi S.Smita ,Anup Kumar Singh... 
吲哚生物碱 | 合酶 | 长春花 | 生物合成 | 二磷酸 | 单萜 | GPPS | 香叶 | large subunit | geranyl diphosphate synthase | C. roseus | heteromer | homomer | monoterpene indole alkaloids | small subunit | vindoline | MADAGASCAR PERIWINKLE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SPRUCE PICEA-ABIES | PYROPHOSPHATE SYNTHASE | CHAIN-LENGTH SPECIFICITY | PLANT SCIENCES | PERFORMANCE LIQUID-CHROMATOGRAPHY | ISOPRENOID BIOSYNTHESIS | FUNCTIONAL EXPRESSION | roseus | FARNESYL DIPHOSPHATE | TRANSCRIPTION FACTOR | OLEORESIN FORMATION | Diphosphates - metabolism | Protein Multimerization | Alkyl and Aryl Transferases - metabolism | DNA, Complementary - genetics | Molecular Sequence Data | Phylogeny | Genetic Complementation Test | Recombinant Proteins - isolation & purification | Biosynthetic Pathways - genetics | Alkyl and Aryl Transferases - genetics | Plant Proteins - chemistry | Escherichia coli - metabolism | Gene Expression Regulation, Plant | Spatio-Temporal Analysis | Plant Proteins - metabolism | Diterpenes - metabolism | Recombinant Proteins - metabolism | Alkyl and Aryl Transferases - chemistry | Amino Acid Sequence | Catharanthus - enzymology | Enzyme Assays | DNA, Complementary - isolation & purification | Plant Proteins - genetics | Plant Leaves - genetics | Plant Leaves - growth & development | Monoterpenes - metabolism | Indole Alkaloids - metabolism | Subcellular Fractions - enzymology
Journal Article
Plant biotechnology journal, ISSN 1467-7644, 2015, Volume 13, Issue 9, pp. 1287 - 1299
Journal Article
The New phytologist, ISSN 0028-646X, 2017, Volume 215, Issue 3, pp. 1115 - 1131
Summary Withania somnifera produces pharmacologically important triterpenoid withanolides that are derived via phytosterol pathway; however, their biosynthesis... 
phytosterols | overexpression | regulation | triterpenoids | virus‐induced gene silencing (VIGS) | withanolides | Withania somnifera | WRKY transcription factor | virus-induced gene silencing (VIGS) | MOLECULAR CHARACTERIZATION | WITHAFERIN-A | EXPRESSION ANALYSIS | CATHARANTHUS-ROSEUS | SPECIALIZED METABOLISM | SQUALENE SYNTHASE | STEROL BIOSYNTHESIS | HEVEA-BRASILIENSIS | PROMOTER ANALYSIS | INDOLE ALKALOID BIOSYNTHESIS | PLANT SCIENCES | silencing (VIGS) | virus-induced gene | with-anolides | Gene Silencing - drug effects | Transcription Factors - chemistry | Genes, Plant | Adaptation, Physiological - drug effects | Withania - genetics | Gene Expression Profiling | Promoter Regions, Genetic - genetics | Sequence Analysis, Protein | Biosynthetic Pathways - genetics | Adaptation, Physiological - genetics | Plant Proteins - chemistry | Protein Binding - drug effects | Benzyl Alcohols - pharmacology | Plant Proteins - metabolism | Stress, Physiological - drug effects | Withanolides - metabolism | Amino Acid Sequence | Glucosides - pharmacology | Stress, Physiological - genetics | Cyclopentanes - pharmacology | Transcription Factors - genetics | Down-Regulation - drug effects | Subcellular Fractions - metabolism | Down-Regulation - genetics | Transcription Factors - metabolism | Up-Regulation - drug effects | Plant Proteins - genetics | Gene Expression Regulation, Plant - drug effects | Biosynthetic Pathways - drug effects | Oxylipins - pharmacology | Phytosterols - metabolism | Acetates - pharmacology | Withania - metabolism | Chromatin | Promoters (Genetics) | Metabolites | Analysis | Phytosterols | Physiological aspects | Mycoses | Genetic research | Genetic engineering | DNA binding proteins | Health aspects | Regulations | Transcription factors | Correlation | Immunoprecipitation | Transcription | Triterpenoids | Genes | Viruses | Biosynthesis | Infections | Assaying | Accumulation | Gene sequencing | Fungi | Engineering | Reduction | Pathways | Modulation | Squalene epoxidase | Bacteria | Tomatoes | Jasmonic acid | Stresses | Squalene | Tolerance | Pharmacology | Gene expression | Promoters | Stress | Feeding | Gene silencing | Tobacco | Salicin | Plant growth | Insects | Metabolic engineering
Journal Article
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 04/2019, Volume 85, pp. 82 - 96
[Display omitted] •Biphenyl-3-oxo-1,2,4-triazine linked piperazines were designed and synthesized.•Compound 6g significantly inhibited the AChE and showed good... 
Alzheimer’s disease | Piperazine | Cognitive dysfunctions | Donepezil | Acetylcholinesterase | Butyrylcholinesterase | 1,2,4-triazine | PAMPA-BBB | Alzheimer's disease | DRUG | OXIDATIVE STRESS | DESIGN | ASSAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | TRIAZINE | DISCOVERY | ACID-DERIVATIVES | PATHWAY | ACETYLCHOLINESTERASE INHIBITORS | Memory - drug effects | Learning - drug effects | Nootropic Agents - metabolism | Antioxidants - metabolism | Humans | Torpedo | Male | Piperazines - metabolism | Cholinesterase Inhibitors - chemical synthesis | Biphenyl Compounds - metabolism | Biphenyl Compounds - pharmacology | Cholinesterase Inhibitors - metabolism | Drug Design | Triazines - metabolism | Catalytic Domain | Triazines - pharmacology | Acetylcholinesterase - chemistry | Antioxidants - chemical synthesis | Antioxidants - pharmacology | Nootropic Agents - chemical synthesis | Piperazines - pharmacology | Molecular Dynamics Simulation | Animals | Cholinesterase Inhibitors - pharmacology | Biphenyl Compounds - chemical synthesis | Triazines - chemical synthesis | Cell Line, Tumor | Protein Binding | Piperazines - chemical synthesis | Mice | Molecular Docking Simulation | Acetylcholinesterase - metabolism | Nootropic Agents - pharmacology | Antioxidants | Surface active agents | Analysis | Molecular dynamics | Permeability
Journal Article
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