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1. Full Text omega-Hydroxyemodin Limits Staphylococcus aureus Quorum Sensing-Mediated Pathogenesis and Inflammation
by Daly, SM and Elmore, BO and Kavanaugh, JS and Triplett, KD and Figueroa, M and Raja, HA and El-Elimat, T and Crosby, HA and Femling, JK and Cech, NB and Horswill, AR and Oberlies, NH and Hall, PR
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 04/2015, Volume 59, Issue 4, pp. 2223 - 2235
Antibiotic-resistant pathogens are a global health threat. Small molecules that inhibit bacterial virulence have been suggested as alternatives or adjuncts to... 
VIRULENCE DETERMINANTS | COMMUNITY-ASSOCIATED MRSA | DNA-BINDING | HUMAN NEUTROPHILS | LYTTR DOMAIN | ALPHA-HEMOLYSIN | HOST-DEFENSE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | INFECTION | AGR | IDENTIFICATION
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2. Full Text Engineering Fluorine into Verticillins (Epipolythiodioxopiperazine Alkaloids) via Precursor-Directed Biosynthesis
by Amrine, Chiraz Soumia M and Long, Jessica L and Raja, Huzefa A and Kurina, Steven J and Burdette, Joanna E and Pearce, Cedric J and Oberlies, Nicholas H
Journal of Natural Products, ISSN 0163-3864, 10/2019
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3. Full Text Additional α-glucosidase inhibitors from Malbranchea flavorosea (Leotiomycetes, Ascomycota)
by Rebollar-Ramos, Daniela and Macías-Ruvalcaba, Martha L and Figueroa, Mario and Raja, Huzefa A and González-Andrade, Martín and Mata, Rachel
Journal of Antibiotics, ISSN 0021-8820, 10/2018, Volume 71, Issue 10, pp. 862 - 871
From the rice-based culture of Malbranchea flavorosea, three new compounds namely flavoroseoside B (5-desoxy-5-chloroflavoroseoside) (2),... 
METABOLITES | FUNGI | AMBER | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FORCE-FIELD | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | IMMUNOLOGY | FREE-ENERGY | BINDING | ALKALOIDS
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4. Full Text Mycopyranone: A 8,8E-binaphthopyranone with potent anti-MRSA activity from the fungus Phialemoniopsis sp
by Rivera-Chavez, Jose and Caesar, Lindsay K and Garcia-Salazar, Juan J and Raja, Huzefa A and Cech, Nadja B and Pearce, Cedric J and Oberlies, Nicholas H
Tetrahedron Letters, ISSN 0040-4039, 02/2019, Volume 60, Issue 8, p. 594
Fungi | Analysis | Staphylococcus aureus infections | Esters | Explosives | Fermentation | Tubulins | Staphylococcus aureus
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5. Full Text Meroterpenoids from Neosetophoma sp.: A Dioxa[4.3.3]propellane Ring System, Potent Cytotoxicity, and Prolific Expression
by El-Elimat, Tamam and Raja, Huzefa A and Ayers, Sloan and Kurina, Steven J and Burdette, Joanna E and Mattes, Zachary and Sabatelle, Robert and Bacon, Jeffrey W and Colby, Aaron H and Grinstaff, Mark W and Pearce, Cedric J and Oberlies, Nicholas H
Organic Letters, ISSN 1523-7060, 01/2019, Volume 21, Issue 2, pp. 529 - 534
Six fungal metabolites, of which five were new, including one (1) with a dioxa[4.3.3]propellane ring system, were discovered, identified, and structurally... 
CHEMISTRY, ORGANIC | SESQUITERPENE | FUNGAL | BIOSYNTHESIS | Letter
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6. Full Text Media studies to enhance the production of verticillins facilitated by in situ chemical analysis
by Amrine, Chiraz Soumia M and Raja, Huzefa A and Darveaux, Blaise A and Pearce, Cedric J and Oberlies, Nicholas H
Journal of Industrial Microbiology & Biotechnology, ISSN 1367-5435, 12/2018, Volume 45, Issue 12, pp. 1053 - 1065
Verticillins are a group of epipolythiodioxopiperazine alkaloids that have displayed potent cytotoxicity. To evaluate their potential further, a larger supply... 
Life Sciences | Biochemistry, general | Epipolythiodioxopiperazine alkaloids | Biotechnology | Genetic Engineering | Microbiology | Verticillin | Filamentous fungi | In situ extraction | Inorganic Chemistry | Fermentation | Bioinformatics | SECONDARY METABOLITES | DEREPLICATION | COMPOUND | FUNGAL CULTURES | IDENTIFICATION | MASS-SPECTROMETRY | SOLID-STATE FERMENTATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | COLON-CARCINOMA | Tandem Mass Spectrometry | Indoles - metabolism | Verticillium - metabolism | Phylogeny | Culture Media - chemistry | Gliocladium - metabolism | Penicillium - metabolism | Ascomycota - metabolism | Alkaloids | Plant metabolites | Growth conditions | Analytical chemistry | Chemical analysis | Semisynthesis | Toxicity | Cytotoxicity | Biosynthesis | Fungi | Organic chemistry | Secondary metabolites | Metabolites | Biocompatibility | In vivo methods and tests | Droplets | Natural Products - Original Paper
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7. Full Text Droplet probe: coupling chromatography to the in situ evaluation of the chemistry of nature
by Oberlies, Nicholas H and Knowles, Sonja L and Amrine, Chiraz Soumia M and Kao, Diana and Kertesz, Vilmos and Raja, Huzefa A
Natural Product Reports, ISSN 0265-0568, 07/2019, Volume 36, Issue 7, pp. 944 - 959
Covering: up to 2019The chemistry of nature can be beautiful, inspiring, beneficial and poisonous, depending on perspective. Since the isolation of the first... 
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8. Full Text Metabolites from the marine-facultative Aspergillus sp. MEXU 27854 and Gymnoascus hyalinosporus MEXU 29901 from Caleta Bay, Mexico
by Aparicio-Cuevas, MA and Gonzalez, MD and Raja, HA and Rivero-Cruz, I and Kurina, SJ and Burdette, JE and Oberlies, NH and Figueroa, M
TETRAHEDRON LETTERS, ISSN 0040-4039, 06/2019, Volume 60, Issue 25, pp. 1649 - 1652
During our ongoing research on fungal strains from unexplored sources, the reinvestigation of the CHCl3-MeOH extract of the marine-facultative Aspergillus sp.... 
Fungi | AUSTRALIAN ISOLATE | Metabolites | GYMNASCELLA | MYCOTOXINS ALTERNARIOL | GYMNASTATINS | PEPTAIBOLS | CHEMISTRY, ORGANIC | Ascomycetes | Unexplored | DERIVATIVES | Methyl ether | Analysis
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9. Full Text An unusual Burkholderia gladioli double chain-initiating nonribosomal peptide synthetase assembles 'fungal' icosalide antibioticsElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc04897e
by Jenner, Matthew and Jian, Xinyun and Dashti, Yousef and Masschelein, Joleen and Hobson, Christian and Roberts, Douglas M and Jones, Cerith and Harris, Simon and Parkhill, Julian and Raja, Huzefa A and Oberlies, Nicholas H and Pearce, Cedric J and Mahenthiralingam, Eshwar and Challis, Gregory L
ISSN 2041-6520, 5/2019, Volume 1, Issue 21, pp. 5489 - 5494
Burkholderia is a multi-talented genus of Gram-negative bacteria, which in recent years has become increasingly recognised as a promising source of bioactive... 
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10. Full Text [alpha]-Pyrone derivatives, tetra/hexahydroxanthones, and cyclodepsipeptides from two freshwater fungi
by El-Elimat, Tamam and Raja, Huzefa A and Day, Cynthia S and McFeeters, Hana and McFeeters, Robert L and Oberlies, Nicholas H
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 01/2017, Volume 25, Issue 2, p. 795
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11. Full Text Mycopyranone: A 8,8ˈ-binaphthopyranone with potent anti-MRSA activity from the fungus Phialemoniopsis sp
by Rivera-Chávez, José and Caesar, Lindsay K and Garcia-Salazar, Juan J and Raja, Huzefa A and Cech, Nadja B and Pearce, Cedric J and Oberlies, Nicholas H
Tetrahedron Letters, ISSN 0040-4039, 02/2019, Volume 60, Issue 8, pp. 594 - 597
A new 8,8ˈ-binaphthopyranone (mycopyranone, ) was isolated from a solid fermentation of sp. (fungal strain MSX61662), and the structure was elucidated via... 
Viriditoxin | Phialemoniopsis sp | Binaphthopyranone | FtsZ protein | MRSA | CYTOSKELETON | CHEMISTRY, ORGANIC | IDENTIFICATION | BACTERIAL CYTOKINESIS | CELL-DIVISION | ABSOLUTE-CONFIGURATION | FTSZ | PRODUCTS | BIOSYNTHESIS | RESISTANCE | INFECTIOUS-DISEASES SOCIETY
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12. An unusual Burkholderia gladioli double chain-initiating nonribosomal peptide synthetase assembles ‘fungal’ icosalide antibiotics (Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc04897e)
by Matthew Jenner and Xinyun Jian and Yousef Dashti and Joleen Masschelein and Christian Hobson and Douglas M Roberts and Cerith Jones and Simon Harris and Julian Parkhill and Huzefa A Raja and Nicholas H Oberlies and Cedric J Pearce and Eshwar Mahenthiralingam and Gregory L Challis
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 21, pp. 5489 - 5494
Burkholderia is a multi-talented genus of Gram-negative bacteria, which in recent years has become increasingly recognised as a promising source of bioactive... 
Profiling | Deactivation | Architecture | Peptides | Modules | Chains | Biosynthesis | Gene sequencing | Fungi | Domains | Antibiotics | Condensates | Natural products | Burkholderia | Mass spectrometry | Bioinformatics | Assembly | Deoxyribonucleic acid--DNA
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13. Full Text Alkaloids from the Fungus Penicillium spathulatum as -Glucosidase Inhibitors
by Del Valle, P and Martinez, AL and Figueroa, M and Raja, HA and Mata, R
PLANTA MEDICA, ISSN 0032-0943, 09/2016, Volume 82, Issue 14, pp. 1286 - 1294
Benzomalvin A (1), quinolactacins A1 (2), A2 (3) and B (4), quinolonimide (5), asperphenamate (6), and a new halogenated polyhydroxyanthraquinone, namely... 
CHEMISTRY, MEDICINAL | Penicillium spathulatum | benzomalvin A | CHEMICAL-SHIFTS | ALPHA-GLUCOSIDASE | ASPERPHENAMATE | antihyperglycemic effect | glucosidase inhibitors | IDENTIFICATION | H-1 | QUINOLACTACIN-B | PLANT SCIENCES | SUBSTRATE-SPECIFICITY | INTEGRATIVE & COMPLEMENTARY MEDICINE | Trichocomaceae | PHARMACOLOGY & PHARMACY | INTESTINAL MALTASE-GLUCOAMYLASE | QUINOLONE COMPOUNDS | antihyperalgesic activity | SUBUNIT | Hypoglycemic agents | Research | Properties | Penicillium | Materia medica, Vegetable | Plant extracts
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14. Full Text Prealamethicin F50 and related peptaibols from: Trichoderma arundinaceum: Validation of their authenticity via in situ chemical analysis
by Rivera-Chávez, José and Raja, Huzefa A and Graf, Tyler N and Gallagher, Jacklyn M and Metri, Prashant and Xue, Ding and Pearce, Cedric J and Oberlies, Nicholas H
RSC Advances, ISSN 2046-2069, 2017, Volume 7, Issue 72, pp. 45733 - 45741
In the field of natural products chemistry, a common question pertains to the authenticity of an isolated compound, i.e. are the interesting side chains... 
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15. Full Text Pannorin B, a new naphthopyrone from an endophytic fungal isolate of Penicillium sp
by Kaur, Amninder and Raja, Huzefa A and Deep, Gagan and Agarwal, Rajesh and Oberlies, Nicholas H
Magnetic Resonance in Chemistry, ISSN 0749-1581, 02/2016, Volume 54, Issue 2, pp. 164 - 167
NMR | Silybum marianum | Penicillium sp | 1H NMR | fungal endophyte | 13C NMR | milk thistle | secondary metabolite | MILK THISTLE | SPECTROSCOPY | PRODUCTS | PROSTATE-CANCER | CHEMISTRY, PHYSICAL | SILYBUM-MARIANUM | SILYMARIN | CHEMISTRY, MULTIDISCIPLINARY | FLAVONOLIGNANS | Naphthalenes - chemistry | Lactones - isolation & purification | Diketopiperazines - chemistry | Penicillium | Diketopiperazines - isolation & purification | Naphthols - chemistry | Indoles - isolation & purification | Naphthols - isolation & purification | Naphthalenes - isolation & purification | Pyrones - chemistry | Proton Magnetic Resonance Spectroscopy | Milk Thistle - chemistry | Pyrones - isolation & purification | Indoles - chemistry | Lactones - chemistry | Metabolites
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16. Full Text Dereplicating and Spatial Mapping of Secondary Metabolites from Fungal Culturesin Situ
by Sica, Vincent P and Raja, Huzefa A and El-Elimat, Tamam and Kertesz, Vilmos and Van Berkel, Gary J and Pearce, Cedric J and Oberlies, Nicholas H
Journal of Natural Products, ISSN 0163-3864, 08/2015, Volume 78, Issue 8, pp. 1926 - 1936
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17. Full Text qNMR for profiling the production of fungal secondary metabolites
: qNMR for fungal cultures
by Brooks, Wilson C and Paguigan, Noemi D and Raja, Huzefa A and Moy, Franklin J and Cech, Nadja B and Pearce, Cedric J and Oberlies, Nicholas H
Magnetic Resonance in Chemistry, ISSN 0749-1581, 07/2017, Volume 55, Issue 7, pp. 670 - 676
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18. Full Text Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle)
by Raja, Huzefa A and Kaur, Amninder and El-Elimat, Tamam and Figueroa, Mario and Kumar, Rahul and Deep, Gagan and Agarwal, Rajesh and Faeth, Stanley H and Cech, Nadja B and Oberlies, Nicholas H
Mycology, ISSN 2150-1203, 01/2015, Volume 6, Issue 1, pp. 8 - 27
Use of the herb milk thistle (Silybum marianum) is widespread, and its chemistry has been studied for over 50 years. However, milk thistle endophytes have not... 
Ascomycota | endophyte | Silybum marianum | milk thistle
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19. Full Text Pannorin B, a new naphthopyrone from an endophytic fungal isolate ofPenicilliumsp
: Pannorin B from an endophyticPenicilliumsp
by Kaur, Amninder and Raja, Huzefa A and Deep, Gagan and Agarwal, Rajesh and Oberlies, Nicholas H
Magnetic Resonance in Chemistry, ISSN 0749-1581, 02/2016, Volume 54, Issue 2, pp. 164 - 167
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20. Full Text New diketopiperazine dimer from a filamentous fungal isolate ofAspergillus sydowii
: Diketopiperazine dimer
by Kaur, Amninder and Raja, Huzefa A and Darveaux, Blaise A and Chen, Wei-Lun and Swanson, Steven M and Pearce, Cedric J and Oberlies, Nicholas H
Magnetic Resonance in Chemistry, ISSN 0749-1581, 08/2015, Volume 53, Issue 8, pp. 616 - 619
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