Emerging Infectious Diseases, ISSN 1080-6040, 11/2016, Volume 22, Issue 11, pp. 1908 - 1914
Corynebacterium striatum is an emerging multidrug-resistant bacteria. We retrospectively identified 179 isolates in a clinical database. Clinical relevance, in...
NOSOCOMIAL PATHOGEN | NATIVE VALVE ENDOCARDITIS | INFECTIOUS DISEASES | INFECTIONS | SPECIMENS | DISEASES | SUSCEPTIBILITY | IMMUNOLOGY | LEVEL DAPTOMYCIN RESISTANCE | IDENTIFICATION | EMERGENCE | MASS-SPECTROMETRY | Corynebacterium - isolation & purification | Corynebacterium - drug effects | Anti-Infective Agents - pharmacology | Humans | Corynebacterium Infections - epidemiology | Anti-Infective Agents - therapeutic use | Corynebacterium Infections - microbiology | Case-Control Studies | Washington - epidemiology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Corynebacterium Infections - drug therapy | Prescription Drug Overuse | Drug Resistance, Multiple, Bacterial | Anti-Bacterial Agents - pharmacology | Drugs | Infection | Drug resistance in microorganisms | Usage | Analysis | Staphylococcal infections | Medical records | Health aspects | Antibacterial agents | multidrug resistance | parenteral antimicrobial drugs | bacteria | Multidrug-Resistant | antimicrobial resistance | Associated with Increased Use of Parenteral Antimicrobial Drugs | Research | Corynebacterium striatum
NOSOCOMIAL PATHOGEN | NATIVE VALVE ENDOCARDITIS | INFECTIOUS DISEASES | INFECTIONS | SPECIMENS | DISEASES | SUSCEPTIBILITY | IMMUNOLOGY | LEVEL DAPTOMYCIN RESISTANCE | IDENTIFICATION | EMERGENCE | MASS-SPECTROMETRY | Corynebacterium - isolation & purification | Corynebacterium - drug effects | Anti-Infective Agents - pharmacology | Humans | Corynebacterium Infections - epidemiology | Anti-Infective Agents - therapeutic use | Corynebacterium Infections - microbiology | Case-Control Studies | Washington - epidemiology | Microbial Sensitivity Tests | Anti-Bacterial Agents - therapeutic use | Corynebacterium Infections - drug therapy | Prescription Drug Overuse | Drug Resistance, Multiple, Bacterial | Anti-Bacterial Agents - pharmacology | Drugs | Infection | Drug resistance in microorganisms | Usage | Analysis | Staphylococcal infections | Medical records | Health aspects | Antibacterial agents | multidrug resistance | parenteral antimicrobial drugs | bacteria | Multidrug-Resistant | antimicrobial resistance | Associated with Increased Use of Parenteral Antimicrobial Drugs | Research | Corynebacterium striatum
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 10/2019
Abstract Background Patients with reported beta lactam antibiotic allergies (BLA) are more likely to receive broad-spectrum antibiotics and experience adverse...
Journal Article
Transplant Infectious Disease, ISSN 1398-2273, 06/2017, Volume 19, Issue 3, pp. e12680 - n/a
Infections caused by Diaporthe species are very uncommon. We describe a heart transplant recipient 14 years post transplant who developed a soft tissue fungal...
antifungal therapy | fungal infection | Aspergillus galactomannan | Diaporthe | RECIPIENT | PHOMOPSIS | INFECTIOUS DISEASES | IMMUNOLOGY | TRANSPLANTATION | Immunosuppression - methods | Humans | Thigh - surgery | Glycopeptides - isolation & purification | Mycoses - microbiology | Male | Tomography, X-Ray Computed | DNA, Fungal - isolation & purification | Antifungal Agents - therapeutic use | Ascomycota - pathogenicity | Immunosuppression - adverse effects | Polymerase Chain Reaction | Mycoses - therapy | Mycoses - blood | Mycoses - diagnostic imaging | Triazoles - therapeutic use | Ascomycota - isolation & purification | Thigh - pathology | Soft Tissue Infections - therapy | Heart Transplantation - adverse effects | Soft Tissue Infections - blood | Soft Tissue Infections - microbiology | Thigh - diagnostic imaging | Soft Tissue Infections - diagnostic imaging | Aged | Myocardial Ischemia - surgery | Heart | Organ transplant recipients | Mycoses | Transplantation | Health aspects | Cardiac patients | Therapy | Transplants & implants | Syngeneic grafts | Heart transplantation | Risk | Infections | Patients | Fungi | Surgery | Xenografts | Posaconazole | Avoidance
antifungal therapy | fungal infection | Aspergillus galactomannan | Diaporthe | RECIPIENT | PHOMOPSIS | INFECTIOUS DISEASES | IMMUNOLOGY | TRANSPLANTATION | Immunosuppression - methods | Humans | Thigh - surgery | Glycopeptides - isolation & purification | Mycoses - microbiology | Male | Tomography, X-Ray Computed | DNA, Fungal - isolation & purification | Antifungal Agents - therapeutic use | Ascomycota - pathogenicity | Immunosuppression - adverse effects | Polymerase Chain Reaction | Mycoses - therapy | Mycoses - blood | Mycoses - diagnostic imaging | Triazoles - therapeutic use | Ascomycota - isolation & purification | Thigh - pathology | Soft Tissue Infections - therapy | Heart Transplantation - adverse effects | Soft Tissue Infections - blood | Soft Tissue Infections - microbiology | Thigh - diagnostic imaging | Soft Tissue Infections - diagnostic imaging | Aged | Myocardial Ischemia - surgery | Heart | Organ transplant recipients | Mycoses | Transplantation | Health aspects | Cardiac patients | Therapy | Transplants & implants | Syngeneic grafts | Heart transplantation | Risk | Infections | Patients | Fungi | Surgery | Xenografts | Posaconazole | Avoidance
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 04/2019, Volume 19, Issue 4, p. 1224
Journal Article
Transplantation, ISSN 0041-1337, 04/2018, Volume 102, Issue 4, pp. 632 - 639
BACKGROUNDFew studies have directly compared preemptive therapy (PET) and antiviral prophylaxis (AP) for prevention of cytomegalovirus (CMV) disease in CMV...
SOLID-ORGAN TRANSPLANTATION | SURGERY | STRATEGY | DISEASE | INFECTION | IMMUNOLOGY | TRANSPLANTATION | Prospective Studies | Liver Transplantation - adverse effects | Humans | Middle Aged | Male | Cytomegalovirus Infections - immunology | Opportunistic Infections - prevention & control | Antibodies, Viral - blood | Viral Load | Feasibility Studies | Young Adult | Cytomegalovirus Infections - prevention & control | RNA, Viral - genetics | Time Factors | Cytomegalovirus Infections - virology | Adult | Female | Opportunistic Infections - immunology | Valganciclovir - adverse effects | Opportunistic Infections - blood | Cytomegalovirus - pathogenicity | Cytomegalovirus - genetics | Opportunistic Infections - virology | Drug Administration Schedule | Administration, Oral | Treatment Outcome | Antiviral Agents - administration & dosage | Cytomegalovirus - immunology | Cytomegalovirus Infections - blood | Antiviral Agents - adverse effects | Antibodies, Viral - immunology | Immunosuppressive Agents - adverse effects | Aged | Immunocompromised Host | Valganciclovir - administration & dosage | Cytomegalovirus - drug effects | Prevention | Complications and side effects | Cytomegalovirus infections | Transplantation | Liver
SOLID-ORGAN TRANSPLANTATION | SURGERY | STRATEGY | DISEASE | INFECTION | IMMUNOLOGY | TRANSPLANTATION | Prospective Studies | Liver Transplantation - adverse effects | Humans | Middle Aged | Male | Cytomegalovirus Infections - immunology | Opportunistic Infections - prevention & control | Antibodies, Viral - blood | Viral Load | Feasibility Studies | Young Adult | Cytomegalovirus Infections - prevention & control | RNA, Viral - genetics | Time Factors | Cytomegalovirus Infections - virology | Adult | Female | Opportunistic Infections - immunology | Valganciclovir - adverse effects | Opportunistic Infections - blood | Cytomegalovirus - pathogenicity | Cytomegalovirus - genetics | Opportunistic Infections - virology | Drug Administration Schedule | Administration, Oral | Treatment Outcome | Antiviral Agents - administration & dosage | Cytomegalovirus - immunology | Cytomegalovirus Infections - blood | Antiviral Agents - adverse effects | Antibodies, Viral - immunology | Immunosuppressive Agents - adverse effects | Aged | Immunocompromised Host | Valganciclovir - administration & dosage | Cytomegalovirus - drug effects | Prevention | Complications and side effects | Cytomegalovirus infections | Transplantation | Liver
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 2/2003, Volume 36, Issue 3, pp. 313 - 318
Linezolid is an oxazolidinone that has activity against most gram-positive bacteria, including in vitro activity against all Nocardia species and strains. We...
Nocardia asteroides | Nocardia | Chronic granulomatous disease | Nocardia infections | Antibiotics | Major Articles | Sulfonamides | Antimicrobials | Central nervous system diseases | Infections | Medical cures | ACQUIRED-IMMUNODEFICIENCY-SYNDROME | INFECTIOUS DISEASES | ABSCESS | BRASILIENSIS | ASTEROIDES | FARCINICA | MICROBIOLOGY | PATIENT | IMMUNOLOGY | FAILURE | TRIMETHOPRIM-SULFAMETHOXAZOLE | Linezolid | Anti-Bacterial Agents - therapeutic use | Acetamides - therapeutic use | Humans | Middle Aged | Nocardia - drug effects | Female | Male | Treatment Outcome | Child | Nocardia Infections - drug therapy | Oxazolidinones - therapeutic use | Usage | Product information | Communicable diseases | Research | Drug therapy | Pharmaceutical industry
Nocardia asteroides | Nocardia | Chronic granulomatous disease | Nocardia infections | Antibiotics | Major Articles | Sulfonamides | Antimicrobials | Central nervous system diseases | Infections | Medical cures | ACQUIRED-IMMUNODEFICIENCY-SYNDROME | INFECTIOUS DISEASES | ABSCESS | BRASILIENSIS | ASTEROIDES | FARCINICA | MICROBIOLOGY | PATIENT | IMMUNOLOGY | FAILURE | TRIMETHOPRIM-SULFAMETHOXAZOLE | Linezolid | Anti-Bacterial Agents - therapeutic use | Acetamides - therapeutic use | Humans | Middle Aged | Nocardia - drug effects | Female | Male | Treatment Outcome | Child | Nocardia Infections - drug therapy | Oxazolidinones - therapeutic use | Usage | Product information | Communicable diseases | Research | Drug therapy | Pharmaceutical industry
Journal Article
Emerging Infectious Diseases, ISSN 1080-6040, 2011, Volume 17, Issue 5, pp. 954 - 955
INFECTIOUS DISEASES | PLASMODIUM-FALCIPARUM MALARIA | IMMUNOLOGY | Malaria, Falciparum - drug therapy | Artemisinins - therapeutic use | United States | Humans | Antimalarials - therapeutic use | Antimalarials - supply & distribution | Artemisinins - supply & distribution | Diagnosis | Research | Drug therapy, Combination | Malaria | Drug therapy | Health aspects | Plasmodium falciparum | artemisinins | letter | Letters to the Editor | drug resistance | malaria | microbial
Journal Article
Infection Control and Hospital Epidemiology, ISSN 0899-823X, 09/2010, Volume 31, Issue 9, pp. 881 - 888
BACKGROUND. The rate of influenza vaccination among healthcare workers (HCWs) is low, despite a good rationale and strong recommendations for vaccination from...
Influenza vaccines | Disease transmission | Original Article | Physicians | Vaccination | Nurses | Patient safety | Health care industry | Allergies | Human resources | Diseases | LONG-TERM-CARE | DECLINATION STATEMENTS | INFECTIOUS DISEASES | ADVISORY-COMMITTEE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | WORKING ADULTS | GUILLAIN-BARRE-SYNDROME | SEASONAL INFLUENZA | IMMUNIZATION RATES | ADVERSE-REACTIONS | HAND HYGIENE | RESPIRATORY PROTECTION | Attitude of Health Personnel | Vaccination - economics | Influenza Vaccines - administration & dosage | Vaccination - utilization | Influenza Vaccines - economics | Occupational Health | Humans | Hospitals, University | Immunization Programs - organization & administration | Male | Health Personnel - statistics & numerical data | Mandatory Programs - organization & administration | Washington | Occupational Health Services | Vaccination - statistics & numerical data | Immunization Programs - methods | Influenza Vaccines - supply & distribution | Female | Influenza, Human - prevention & control
Influenza vaccines | Disease transmission | Original Article | Physicians | Vaccination | Nurses | Patient safety | Health care industry | Allergies | Human resources | Diseases | LONG-TERM-CARE | DECLINATION STATEMENTS | INFECTIOUS DISEASES | ADVISORY-COMMITTEE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | WORKING ADULTS | GUILLAIN-BARRE-SYNDROME | SEASONAL INFLUENZA | IMMUNIZATION RATES | ADVERSE-REACTIONS | HAND HYGIENE | RESPIRATORY PROTECTION | Attitude of Health Personnel | Vaccination - economics | Influenza Vaccines - administration & dosage | Vaccination - utilization | Influenza Vaccines - economics | Occupational Health | Humans | Hospitals, University | Immunization Programs - organization & administration | Male | Health Personnel - statistics & numerical data | Mandatory Programs - organization & administration | Washington | Occupational Health Services | Vaccination - statistics & numerical data | Immunization Programs - methods | Influenza Vaccines - supply & distribution | Female | Influenza, Human - prevention & control
Journal Article
Open Forum Infectious Diseases, ISSN 2328-8957, 10/2019, Volume 6, Issue Supplement_2, pp. S935 - S936
Abstract Background Patients with reported β-lactam antibiotic allergies (BLA) are more likely to receive broad-spectrum antibiotics and experience adverse...
Journal Article
Transplantation, ISSN 0041-1337, 01/2014, Volume 97, Issue 2, pp. 206 - 211
Background Short-course directly observed isoniazid plus rifapentine (INH/RPT) combination could have potential advantages over a standard 9-month INH regimen...
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 02/2019, Volume 68, Issue 5, pp. 887 - 889
Journal Article
JAMA, ISSN 0098-7484, 10/2010, Volume 304, Issue 16, pp. 1786 - 1786
Journal Article
Emerging Infectious Diseases, ISSN 1080-6040, 11/2016, Volume 22, Issue 11
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 07/2017, Volume 65, Issue 1, pp. 57 - 63
Background. Ganciclovir-resistant (ganR) cytomegalovirus (CMV) is an emerging and important problem in solid organ transplant (SOT) recipients. Only through...
ganciclovir resistance | risk factors | cytomegalovirus | outcomes | solid organ transplant | INFECTIOUS DISEASES | MICROBIOLOGY | IMMUNOLOGY | EMERGENCE | PROPHYLAXIS | IMPACT | UL97 | FOSCARNET | ERA | DISEASE | SAMPLES | RAPID DETECTION | Antiviral Agents - pharmacology | Antiviral Agents - therapeutic use | Cytomegalovirus Infections - epidemiology | Humans | Middle Aged | Risk Factors | Male | Treatment Outcome | Morbidity | Incidence | Cytomegalovirus Infections - drug therapy | Cytomegalovirus Infections - virology | Ganciclovir - therapeutic use | Adult | Female | Ganciclovir - pharmacology | Retrospective Studies | Cytomegalovirus - drug effects | Transplant Recipients - statistics & numerical data | Care and treatment | Ganciclovir | Usage | Analysis | Organ transplant recipients | Outcome and process assessment (Health Care) | Cytomegalovirus infections | Research | and Commentaries
ganciclovir resistance | risk factors | cytomegalovirus | outcomes | solid organ transplant | INFECTIOUS DISEASES | MICROBIOLOGY | IMMUNOLOGY | EMERGENCE | PROPHYLAXIS | IMPACT | UL97 | FOSCARNET | ERA | DISEASE | SAMPLES | RAPID DETECTION | Antiviral Agents - pharmacology | Antiviral Agents - therapeutic use | Cytomegalovirus Infections - epidemiology | Humans | Middle Aged | Risk Factors | Male | Treatment Outcome | Morbidity | Incidence | Cytomegalovirus Infections - drug therapy | Cytomegalovirus Infections - virology | Ganciclovir - therapeutic use | Adult | Female | Ganciclovir - pharmacology | Retrospective Studies | Cytomegalovirus - drug effects | Transplant Recipients - statistics & numerical data | Care and treatment | Ganciclovir | Usage | Analysis | Organ transplant recipients | Outcome and process assessment (Health Care) | Cytomegalovirus infections | Research | and Commentaries
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 07/2017, Volume 65, Issue 1, p. 57
Background. Ganciclovir-resistant (ganR) cytomegalovirus (CMV) is an emerging and important problem in solid organ transplant (SOT) recipients. Only through...
Cytomegalovirus | Renal function | Transplants & implants | Thresholds | Syngeneic grafts | Mortality | Lung transplantation | Exposure | Infections | Drug resistance | Risk analysis | Risk factors | Clinical outcomes | Morbidity | Ganciclovir | Xenografts | Diagnosis | Kidney transplantation
Cytomegalovirus | Renal function | Transplants & implants | Thresholds | Syngeneic grafts | Mortality | Lung transplantation | Exposure | Infections | Drug resistance | Risk analysis | Risk factors | Clinical outcomes | Morbidity | Ganciclovir | Xenografts | Diagnosis | Kidney transplantation
Journal Article
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Full Text
Intracranial Mycotic Aneurysm Associated With Left Ventricular Assist Device Infection
Annals of Thoracic Surgery, ISSN 0003-4975, 2014, Volume 98, Issue 3, pp. 1088 - 1089
Infection is a frequent complication of left ventricular assist device (LVAD) use in patients with severe heart failure. The development of bacteremia with...
Surgery | Cardiothoracic Surgery | SURGERY | RESPIRATORY SYSTEM | CARDIAC & CARDIOVASCULAR SYSTEMS | Aneurysm, Infected - etiology | Intracranial Aneurysm - etiology | Intracranial Aneurysm - microbiology | Humans | Middle Aged | Prosthesis-Related Infections - etiology | Male | Heart-Assist Devices - adverse effects | Aneurysms | Health aspects | Cardiac patients | Endocarditis
Surgery | Cardiothoracic Surgery | SURGERY | RESPIRATORY SYSTEM | CARDIAC & CARDIOVASCULAR SYSTEMS | Aneurysm, Infected - etiology | Intracranial Aneurysm - etiology | Intracranial Aneurysm - microbiology | Humans | Middle Aged | Prosthesis-Related Infections - etiology | Male | Heart-Assist Devices - adverse effects | Aneurysms | Health aspects | Cardiac patients | Endocarditis
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 04/2019, Volume 19, Issue 4, pp. 1224 - 1228
Transplant tourism, which is the practice of traveling to other countries for transplant, continues to be a major problem worldwide. We describe a patient who...
infectious disease | organ transplantation in general | clinical research/practice | kidney transplantation/nephrology | organ sale/trade | infection and infectious agents ‐ bacterial | complication: infectious | antibiotic: antibacterial | infection and infectious agents ‐ fungal | infection and infectious agents - bacterial | infection and infectious agents - fungal | antibiotic | SURGERY | infectious | RISKS | practice | complication | organ sale | kidney transplantation | antibacterial | MUCORMYCOSIS | TRANSPLANTATION | nephrology | trade | clinical research | Tourism | Kidneys | Nephrectomy | Syngeneic grafts | Aztreonam | Infections | Ceftazidime | Contamination | Kidney transplantation
infectious disease | organ transplantation in general | clinical research/practice | kidney transplantation/nephrology | organ sale/trade | infection and infectious agents ‐ bacterial | complication: infectious | antibiotic: antibacterial | infection and infectious agents ‐ fungal | infection and infectious agents - bacterial | infection and infectious agents - fungal | antibiotic | SURGERY | infectious | RISKS | practice | complication | organ sale | kidney transplantation | antibacterial | MUCORMYCOSIS | TRANSPLANTATION | nephrology | trade | clinical research | Tourism | Kidneys | Nephrectomy | Syngeneic grafts | Aztreonam | Infections | Ceftazidime | Contamination | Kidney transplantation
Journal Article
Mycopathologia, ISSN 0301-486X, 10/2019, Volume 184, Issue 5, pp. 671 - 676
Medicopsis species are rare fungal pathogens that frequently resist common antifungal therapies and are difficult to identify morphologically as conidia are...
Life Sciences | Medical Microbiology | Microbial Ecology | Microbiology | Coelomycete | Dematiaceous | Phaeohyphomycosis | Mycetoma | Plant Sciences | Medicopsis | Solid-organ transplant | Eukaryotic Microbiology | Fungicides | Identification methods | Health risks | Infections | Rare species | Mimicry | Soft tissues | Fungi | Pycnidia | Immunocompromised hosts | Health risk assessment | Posaconazole | Kidney transplantation | Conidia
Life Sciences | Medical Microbiology | Microbial Ecology | Microbiology | Coelomycete | Dematiaceous | Phaeohyphomycosis | Mycetoma | Plant Sciences | Medicopsis | Solid-organ transplant | Eukaryotic Microbiology | Fungicides | Identification methods | Health risks | Infections | Rare species | Mimicry | Soft tissues | Fungi | Pycnidia | Immunocompromised hosts | Health risk assessment | Posaconazole | Kidney transplantation | Conidia
Journal Article
Microbial Drug Resistance, ISSN 1076-6294, 04/2016, Volume 22, Issue 3, pp. 233 - 237
Introduction: We describe the clinical and microbiologic courses of two patients with ventricular assist device infections secondary to Corynebacterium...
NOSOCOMIAL PATHOGEN | NATIVE VALVE ENDOCARDITIS | INFECTIOUS DISEASES | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | Corynebacterium - isolation & purification | Staphylococcal Infections - drug therapy | Corynebacterium - drug effects | Humans | Methicillin-Resistant Staphylococcus aureus - drug effects | Male | Corynebacterium Infections - microbiology | Heart-Assist Devices - microbiology | Daptomycin - pharmacology | Corynebacterium Infections - drug therapy | Aged | Anti-Bacterial Agents - pharmacology | Staphylococcal Infections - microbiology | Drug Resistance, Bacterial - drug effects | Methicillin-Resistant Staphylococcus aureus - isolation & purification | Microbial Sensitivity Tests - methods | Microbiology | Drug resistance | Infections
NOSOCOMIAL PATHOGEN | NATIVE VALVE ENDOCARDITIS | INFECTIOUS DISEASES | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | Corynebacterium - isolation & purification | Staphylococcal Infections - drug therapy | Corynebacterium - drug effects | Humans | Methicillin-Resistant Staphylococcus aureus - drug effects | Male | Corynebacterium Infections - microbiology | Heart-Assist Devices - microbiology | Daptomycin - pharmacology | Corynebacterium Infections - drug therapy | Aged | Anti-Bacterial Agents - pharmacology | Staphylococcal Infections - microbiology | Drug Resistance, Bacterial - drug effects | Methicillin-Resistant Staphylococcus aureus - isolation & purification | Microbial Sensitivity Tests - methods | Microbiology | Drug resistance | Infections
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2003, Volume 348, Issue 1, pp. 86 - 87
To the Editor: Linezolid is an oxazolidinone antibiotic used to treat a variety of gram-positive infections, including those due to methicillin-resistant...
MEDICINE, GENERAL & INTERNAL | Linezolid | Acidosis, Lactic - chemically induced | Anti-Infective Agents - adverse effects | Humans | Middle Aged | Acetamides - adverse effects | Female | Oxazolidinones - adverse effects | Nocardia Infections - drug therapy
MEDICINE, GENERAL & INTERNAL | Linezolid | Acidosis, Lactic - chemically induced | Anti-Infective Agents - adverse effects | Humans | Middle Aged | Acetamides - adverse effects | Female | Oxazolidinones - adverse effects | Nocardia Infections - drug therapy
Journal Article
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