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Journal of Clinical Oncology, ISSN 0732-183X, 06/2011, Volume 29, Issue 18, pp. 2493 - 2498
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 28, pp. 12605 - 12610
Journal Article
Journal Article
Journal Article
Molecular Immunology, ISSN 0161-5890, 2006, Volume 43, Issue 8, pp. 1129 - 1143
Journal Article
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 585 - 585
BiTE therapeutics are single chain antibody constructs harboring two binding moieties: one directed at a tumor associated antigen and one directed at the CD3e... 
Journal Article
Journal of Immunotherapy, ISSN 1524-9557, 06/2009, Volume 32, Issue 5, pp. 452 - 464
muS110 is a BiTE antibody bispecific for marine EpCAM (CD326) and marine CD3. MT110, its human-specific analog, is in a clinical phase 1 trial for treatment of... 
Anergy | EpCAM | MT110 | Bispecific antibody | Glucocorticoid | IL-10 | CD3 | Cytotoxic T cell | Therapeutic window | Cytokine release | MuS110 | Mouse model | Cancer | MEDICINE, RESEARCH & EXPERIMENTAL | cytokine release | glucocorticoid | CONSTRUCT | mouse model | ANTI-CD3 MONOCLONAL-ANTIBODY | MURINE CD3 | SINGLE-CHAIN ANTIBODY | TUMOR-CELLS | IMMUNOLOGY | CANCER-THERAPY | anergy | cytotoxic T cell | muS110 | ONCOLOGY | therapeutic window | INTERLEUKIN-10 PRODUCTION | bispecific antibody | cancer | Mammary Neoplasms, Experimental - immunology | Neoplasm Transplantation | Cell Adhesion Molecules - genetics | Humans | Cell Adhesion Molecules - immunology | Epithelial Cell Adhesion Molecule | CD3 Complex - genetics | Clonal Anergy - drug effects | T-Lymphocytes - metabolism | Time Factors | T-Lymphocytes - drug effects | Antibodies, Bispecific - administration & dosage | Immunotherapy | Mammary Neoplasms, Experimental - pathology | Protein Engineering | Antigens, Neoplasm - metabolism | Female | T-Lymphocytes - pathology | Antigens, Neoplasm - genetics | Cytokines - metabolism | Antigens, Neoplasm - immunology | Immunologic Factors - administration & dosage | CD3 Complex - metabolism | Cell Adhesion Molecules - metabolism | Mammary Neoplasms, Experimental - therapy | Animals | Antibodies, Bispecific - adverse effects | Lymphocyte Activation - drug effects | CD3 Complex - immunology | T-Lymphocytes - immunology | Cell Proliferation - drug effects | Immunologic Factors - adverse effects | Mice | Mice, Inbred BALB C | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 04/2007, Volume 67, Issue 8, pp. 3927 - 3935
The EphA2 receptor tyrosine kinase is frequently overexpressed and functionally altered in malignant cells and thus provides opportunities for selective... 
Journal Article
Cancer Research, ISSN 0008-5472, 01/2008, Volume 68, Issue 1, pp. 143 - 151
EpCAM (CD326) is one of the most frequently and highly expressed tumor-associated antigens known and recently has also been found on cancer stem cells derived... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2010, Volume 107, Issue 28, p. 12605
  Epidermal growth factor receptor (EGFR)-specific monoclonal antibodies predominantly inhibit colorectal cancer (CRC) growth by interfering with receptor... 
Colorectal cancer | Oncology | T cell receptors | Mutation | Binding sites | Immune system
Journal Article
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 7/2006, Volume 55, Issue 7, pp. 785 - 796
Journal Article
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