Journal of Virology, ISSN 0022-538X, 04/2010, Volume 84, Issue 7, pp. 3134 - 3146
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ANGIOTENSIN-CONVERTING ENZYME-2 | ACUTE-RESPIRATORY-SYNDROME | VIROLOGY | MOUSE HEPATITIS-VIRUS | TARGETED RNA RECOMBINATION | CHINESE HORSESHOE BATS | AMINO-ACID SUBSTITUTIONS | SARS-ASSOCIATED CORONAVIRUS | INFECTIOUS-BRONCHITIS-VIRUS | HUMAN MONOCLONAL-ANTIBODIES | RECEPTOR-BINDING DOMAIN | Amino Acid Sequence | Viral Envelope Proteins - physiology | Species Specificity | Disease Reservoirs - virology | Gene Frequency | Humans | Membrane Glycoproteins - chemistry | Severe Acute Respiratory Syndrome - transmission | Molecular Sequence Data | Receptors, Virus - physiology | Spike Glycoprotein, Coronavirus | Membrane Glycoproteins - physiology | Animals | SARS Virus - genetics | Viral Fusion Proteins - chemistry | Recombination, Genetic | Viral Envelope Proteins - chemistry | Viral Tropism | Binding Sites | Viral Fusion Proteins - physiology | Minireview
ANGIOTENSIN-CONVERTING ENZYME-2 | ACUTE-RESPIRATORY-SYNDROME | VIROLOGY | MOUSE HEPATITIS-VIRUS | TARGETED RNA RECOMBINATION | CHINESE HORSESHOE BATS | AMINO-ACID SUBSTITUTIONS | SARS-ASSOCIATED CORONAVIRUS | INFECTIOUS-BRONCHITIS-VIRUS | HUMAN MONOCLONAL-ANTIBODIES | RECEPTOR-BINDING DOMAIN | Amino Acid Sequence | Viral Envelope Proteins - physiology | Species Specificity | Disease Reservoirs - virology | Gene Frequency | Humans | Membrane Glycoproteins - chemistry | Severe Acute Respiratory Syndrome - transmission | Molecular Sequence Data | Receptors, Virus - physiology | Spike Glycoprotein, Coronavirus | Membrane Glycoproteins - physiology | Animals | SARS Virus - genetics | Viral Fusion Proteins - chemistry | Recombination, Genetic | Viral Envelope Proteins - chemistry | Viral Tropism | Binding Sites | Viral Fusion Proteins - physiology | Minireview
Journal Article
Nature Reviews Microbiology, ISSN 1740-1526, 12/2013, Volume 11, Issue 12, pp. 836 - 848
Two novel coronaviruses have emerged in humans in the twenty-first century: severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East...
PROTECTIVE IMMUNITY | T-CELL RESPONSES | NEUTRALIZING ANTIBODY | IMMUNE-RESPONSES | HUMAN MONOCLONAL-ANTIBODY | SPIKE PROTEIN | MICROBIOLOGY | ACUTE RESPIRATORY SYNDROME | FUNCTIONAL RECEPTOR | RECEPTOR-BINDING DOMAIN | WHOLE KILLED VIRUS | Coronavirus Infections - prevention & control | Coronavirus - pathogenicity | Receptors, Virus - metabolism | Humans | Drug Discovery - trends | Communicable Diseases, Emerging - epidemiology | Viral Vaccines - isolation & purification | Communicable Diseases, Emerging - prevention & control | Coronavirus Infections - epidemiology | Coronavirus - genetics | Viral Tropism | Viral Vaccines - immunology | Coronavirus - physiology | Coronavirus - isolation & purification | Antiviral agents | Research | Coronaviruses | Drug therapy | Health aspects | Severe acute respiratory syndrome
PROTECTIVE IMMUNITY | T-CELL RESPONSES | NEUTRALIZING ANTIBODY | IMMUNE-RESPONSES | HUMAN MONOCLONAL-ANTIBODY | SPIKE PROTEIN | MICROBIOLOGY | ACUTE RESPIRATORY SYNDROME | FUNCTIONAL RECEPTOR | RECEPTOR-BINDING DOMAIN | WHOLE KILLED VIRUS | Coronavirus Infections - prevention & control | Coronavirus - pathogenicity | Receptors, Virus - metabolism | Humans | Drug Discovery - trends | Communicable Diseases, Emerging - epidemiology | Viral Vaccines - isolation & purification | Communicable Diseases, Emerging - prevention & control | Coronavirus Infections - epidemiology | Coronavirus - genetics | Viral Tropism | Viral Vaccines - immunology | Coronavirus - physiology | Coronavirus - isolation & purification | Antiviral agents | Research | Coronaviruses | Drug therapy | Health aspects | Severe acute respiratory syndrome
Journal Article
PLoS Pathogens, ISSN 1553-7366, 05/2012, Volume 8, Issue 5, p. e1002705
Noroviruses are the principal cause of epidemic gastroenteritis worldwide with GII.4 strains accounting for 80% of infections. The major capsid protein of...
CAPSID PROTEIN FORMS | UNITED-STATES | ACUTE GASTROENTERITIS | MICROBIOLOGY | ROUND-STRUCTURED VIRUSES | VACCINE DEVELOPMENT | VIROLOGY | GII-4 NOROVIRUS | NORWALK-LIKE VIRUSES | BLOOD GROUP ANTIGENS | P-DOMAIN | MONOCLONAL-ANTIBODIES | PARASITOLOGY | Amino Acid Sequence | Antibody Specificity | Caliciviridae Infections - virology | Antigenic Variation | Humans | Cells, Cultured | Gastroenteritis - virology | Norovirus - immunology | Epitopes - immunology | Antigens, Viral - immunology | B-Lymphocytes - immunology | Capsid Proteins - chemistry | Vaccines, Virus-Like Particle | Capsid Proteins - immunology | Antibodies, Viral - immunology | Gastroenteritis - immunology | Antibodies, Monoclonal - immunology | Caliciviridae Infections - immunology | Evolution, Molecular | Norovirus - genetics | Immunogenetics | Norovirus | Genetic variation | Viral genetics | Physiological aspects | Genetic aspects | Research | Virulence (Microbiology) | Health aspects | Proteins | Plasma | Carbohydrates | Disease | Infections | Vaccines | Crystal structure
CAPSID PROTEIN FORMS | UNITED-STATES | ACUTE GASTROENTERITIS | MICROBIOLOGY | ROUND-STRUCTURED VIRUSES | VACCINE DEVELOPMENT | VIROLOGY | GII-4 NOROVIRUS | NORWALK-LIKE VIRUSES | BLOOD GROUP ANTIGENS | P-DOMAIN | MONOCLONAL-ANTIBODIES | PARASITOLOGY | Amino Acid Sequence | Antibody Specificity | Caliciviridae Infections - virology | Antigenic Variation | Humans | Cells, Cultured | Gastroenteritis - virology | Norovirus - immunology | Epitopes - immunology | Antigens, Viral - immunology | B-Lymphocytes - immunology | Capsid Proteins - chemistry | Vaccines, Virus-Like Particle | Capsid Proteins - immunology | Antibodies, Viral - immunology | Gastroenteritis - immunology | Antibodies, Monoclonal - immunology | Caliciviridae Infections - immunology | Evolution, Molecular | Norovirus - genetics | Immunogenetics | Norovirus | Genetic variation | Viral genetics | Physiological aspects | Genetic aspects | Research | Virulence (Microbiology) | Health aspects | Proteins | Plasma | Carbohydrates | Disease | Infections | Vaccines | Crystal structure
Journal Article
The Journal of Pathology, ISSN 0022-3417, 01/2015, Volume 235, Issue 2, pp. 185 - 195
Respiratory viruses can cause a wide spectrum of pulmonary diseases, ranging from mild, upper respiratory tract infections to severe and life‐threatening lower...
SARS‐CoV | type II pneumocytes | MERS‐CoV | acute respiratory distress syndrome | coronavirus | acute lung injury | ARDS | Acute respiratory distress syndrome | Acute lung injury | Coronavirus | SARS-CoV | Type II pneumocytes | MERS-CoV | DISTRESS-SYNDROME | CLINICAL-FEATURES | PATHOLOGY | ACUTE RESPIRATORY SYNDROME | DROMEDARY CAMELS | COAGULATION CASCADE | MERS-CORONAVIRUS | SARS-LIKE CORONAVIRUS | ONCOLOGY | IMMUNE-RESPONSES | PULMONARY PATHOLOGY | ACCESSORY PROTEINS | Respiratory System - pathology | Predictive Value of Tests | Severe Acute Respiratory Syndrome - virology | Coronavirus Infections - drug therapy | Humans | Virulence | Respiratory System - virology | Coronavirus - drug effects | Pathology, Molecular - methods | Respiratory System - immunology | Coronavirus - isolation & purification | Communicable Diseases, Emerging | SARS Virus - isolation & purification | Coronavirus - pathogenicity | Antiviral Agents - therapeutic use | Risk Factors | Immunity, Innate | Severe Acute Respiratory Syndrome - drug therapy | Virology - methods | Coronavirus Infections - immunology | SARS Virus - pathogenicity | Coronavirus - immunology | Host-Pathogen Interactions | Middle East Respiratory Syndrome Coronavirus - pathogenicity | Animals | Coronavirus Infections - virology | Biopsy | Coronavirus Infections - pathology | Middle East Respiratory Syndrome Coronavirus - isolation & purification | Respiratory System - drug effects | Severe Acute Respiratory Syndrome - pathology | Biological response modifiers | Health aspects | Invited Reviews
SARS‐CoV | type II pneumocytes | MERS‐CoV | acute respiratory distress syndrome | coronavirus | acute lung injury | ARDS | Acute respiratory distress syndrome | Acute lung injury | Coronavirus | SARS-CoV | Type II pneumocytes | MERS-CoV | DISTRESS-SYNDROME | CLINICAL-FEATURES | PATHOLOGY | ACUTE RESPIRATORY SYNDROME | DROMEDARY CAMELS | COAGULATION CASCADE | MERS-CORONAVIRUS | SARS-LIKE CORONAVIRUS | ONCOLOGY | IMMUNE-RESPONSES | PULMONARY PATHOLOGY | ACCESSORY PROTEINS | Respiratory System - pathology | Predictive Value of Tests | Severe Acute Respiratory Syndrome - virology | Coronavirus Infections - drug therapy | Humans | Virulence | Respiratory System - virology | Coronavirus - drug effects | Pathology, Molecular - methods | Respiratory System - immunology | Coronavirus - isolation & purification | Communicable Diseases, Emerging | SARS Virus - isolation & purification | Coronavirus - pathogenicity | Antiviral Agents - therapeutic use | Risk Factors | Immunity, Innate | Severe Acute Respiratory Syndrome - drug therapy | Virology - methods | Coronavirus Infections - immunology | SARS Virus - pathogenicity | Coronavirus - immunology | Host-Pathogen Interactions | Middle East Respiratory Syndrome Coronavirus - pathogenicity | Animals | Coronavirus Infections - virology | Biopsy | Coronavirus Infections - pathology | Middle East Respiratory Syndrome Coronavirus - isolation & purification | Respiratory System - drug effects | Severe Acute Respiratory Syndrome - pathology | Biological response modifiers | Health aspects | Invited Reviews
Journal Article
Journal of Virology, ISSN 0022-538X, 01/2011, Volume 85, Issue 1, pp. 231 - 242
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GENETIC-ANALYSIS | VIROLOGY | NEUTRALIZING ANTIBODY | SEQUENCE ALIGNMENT | VIRAL GASTROENTERITIS | NORWALK-LIKE VIRUSES | MOLECULAR EPIDEMIOLOGY | ROUND-STRUCTURED VIRUSES | MONOCLONAL-ANTIBODIES | EPOCHAL EVOLUTION | HUMAN-POPULATIONS | Virion - immunology | Immunization | Caliciviridae Infections - prevention & control | Caliciviridae Infections - virology | Antigenic Variation | Humans | Gastroenteritis - virology | Norovirus - immunology | Phylogeny | Epitopes - genetics | Gastroenteritis - prevention & control | Antibodies, Viral - blood | Antibodies, Monoclonal - blood | Epitopes - immunology | Animals | Capsid Proteins - immunology | Antibodies, Viral - immunology | Ligands | Mice | Gastroenteritis - immunology | Antibodies, Monoclonal - immunology | Caliciviridae Infections - immunology | Capsid Proteins - genetics | Norovirus - genetics | Genetic Diversity and Evolution
GENETIC-ANALYSIS | VIROLOGY | NEUTRALIZING ANTIBODY | SEQUENCE ALIGNMENT | VIRAL GASTROENTERITIS | NORWALK-LIKE VIRUSES | MOLECULAR EPIDEMIOLOGY | ROUND-STRUCTURED VIRUSES | MONOCLONAL-ANTIBODIES | EPOCHAL EVOLUTION | HUMAN-POPULATIONS | Virion - immunology | Immunization | Caliciviridae Infections - prevention & control | Caliciviridae Infections - virology | Antigenic Variation | Humans | Gastroenteritis - virology | Norovirus - immunology | Phylogeny | Epitopes - genetics | Gastroenteritis - prevention & control | Antibodies, Viral - blood | Antibodies, Monoclonal - blood | Epitopes - immunology | Animals | Capsid Proteins - immunology | Antibodies, Viral - immunology | Ligands | Mice | Gastroenteritis - immunology | Antibodies, Monoclonal - immunology | Caliciviridae Infections - immunology | Capsid Proteins - genetics | Norovirus - genetics | Genetic Diversity and Evolution
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2014, Volume 111, Issue 34, pp. 12516 - 12521
Middle East respiratory syndrome coronavirus (MERS-CoV) currently spreads in humans and causes ~36% fatality in infected patients. Believed to have originated...
Bats | Receptors | Coronavirus | Disease transmission | Humans | Cell lines | Retroviridae | Viruses | Infections | SARS virus | DROMEDARY CAMELS | NEUTRALIZING ANTIBODIES | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | SPIKE PROTEIN | BINDING DOMAIN | COV | RESPIRATORY SYNDROME CORONAVIRUS | SARS-CORONAVIRUS | SAUDI-ARABIA | VIRAL ENTRY | Chiroptera - virology | Coronavirus - classification | Coronavirus - pathogenicity | Disease Reservoirs - virology | Virulence | Host Specificity | Virus Internalization | Receptors, Virus - physiology | Coronavirus Infections - transmission | Dipeptidyl Peptidase 4 - physiology | Host-Pathogen Interactions | Middle East | Spike Glycoprotein, Coronavirus - physiology | Animals | Coronavirus Infections - virology | Respiratory Tract Infections - transmission | Respiratory Tract Infections - virology | Coronavirus - physiology | Microbiological research | Cell receptors | Physiological aspects | Research | Coronaviruses | Health aspects | Biological Sciences
Bats | Receptors | Coronavirus | Disease transmission | Humans | Cell lines | Retroviridae | Viruses | Infections | SARS virus | DROMEDARY CAMELS | NEUTRALIZING ANTIBODIES | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | SPIKE PROTEIN | BINDING DOMAIN | COV | RESPIRATORY SYNDROME CORONAVIRUS | SARS-CORONAVIRUS | SAUDI-ARABIA | VIRAL ENTRY | Chiroptera - virology | Coronavirus - classification | Coronavirus - pathogenicity | Disease Reservoirs - virology | Virulence | Host Specificity | Virus Internalization | Receptors, Virus - physiology | Coronavirus Infections - transmission | Dipeptidyl Peptidase 4 - physiology | Host-Pathogen Interactions | Middle East | Spike Glycoprotein, Coronavirus - physiology | Animals | Coronavirus Infections - virology | Respiratory Tract Infections - transmission | Respiratory Tract Infections - virology | Coronavirus - physiology | Microbiological research | Cell receptors | Physiological aspects | Research | Coronaviruses | Health aspects | Biological Sciences
Journal Article
Nature Reviews Microbiology, ISSN 1740-1526, 03/2010, Volume 8, Issue 3, pp. 231 - 241
Noroviruses are the most common cause of food-borne gastroenteritis worldwide, and explosive outbreaks frequently occur in community settings, where the virus...
INFECTIOUS NONBACTERIAL GASTROENTERITIS | UNITED-STATES | MOLECULAR CHARACTERIZATION | EQUINE ENCEPHALITIS-VIRUS | REPLICON PARTICLES | NORWALK-LIKE VIRUSES | P2 DOMAIN | MICROBIOLOGY | BLOOD GROUP ANTIGENS | ROUND-STRUCTURED VIRUSES | HUMAN CALICIVIRUS MEXICO | Norovirus - physiology | Caliciviridae Infections - virology | Immune Evasion | Humans | Capsid Proteins - immunology | Gastroenteritis - virology | Norovirus - immunology | Gastroenteritis - immunology | Viral Vaccines - immunology | Caliciviridae Infections - immunology | Norovirus | Gastroenteritis | Causes of | Immune recognition | Physiological aspects | Development and progression | Genetic aspects | Research
INFECTIOUS NONBACTERIAL GASTROENTERITIS | UNITED-STATES | MOLECULAR CHARACTERIZATION | EQUINE ENCEPHALITIS-VIRUS | REPLICON PARTICLES | NORWALK-LIKE VIRUSES | P2 DOMAIN | MICROBIOLOGY | BLOOD GROUP ANTIGENS | ROUND-STRUCTURED VIRUSES | HUMAN CALICIVIRUS MEXICO | Norovirus - physiology | Caliciviridae Infections - virology | Immune Evasion | Humans | Capsid Proteins - immunology | Gastroenteritis - virology | Norovirus - immunology | Gastroenteritis - immunology | Viral Vaccines - immunology | Caliciviridae Infections - immunology | Norovirus | Gastroenteritis | Causes of | Immune recognition | Physiological aspects | Development and progression | Genetic aspects | Research
Journal Article
PLoS Medicine, ISSN 1549-1277, 02/2008, Volume 5, Issue 2, pp. 0269 - 0290
Background Noroviruses are the leading cause of viral acute gastroenteritis in humans, noted for causing epidemic outbreaks in communities, the military,...
CAPSID PROTEIN FORMS | MILK CONTAINS ELEMENTS | MEDICINE, GENERAL & INTERNAL | VIRAL GASTROENTERITIS | MURINE POLYOMAVIRUS | MOUTH-DISEASE VIRUS | MOLECULAR EPIDEMIOLOGY | CODON ALIGNMENTS | BLOOD GROUP ANTIGENS | NORWALK VIRUS-INFECTION | MONOCLONAL-ANTIBODIES | Norovirus - physiology | Amino Acid Sequence | Caliciviridae Infections - prevention & control | Caliciviridae Infections - genetics | Humans | Molecular Sequence Data | Capsid - physiology | Phylogeny | Caliciviridae Infections - transmission | Animals | Binding Sites - physiology | Disease Outbreaks - prevention & control | Mice | Norovirus - genetics | Protein Structure, Tertiary - physiology | Infectious Diseases | Microbiology | Epidemiology | Gastroenteritis | Virology | Carbohydrates | Influenza | Colleges & universities | Writing | Viruses | Ligands | Infections | Genetic algorithms
CAPSID PROTEIN FORMS | MILK CONTAINS ELEMENTS | MEDICINE, GENERAL & INTERNAL | VIRAL GASTROENTERITIS | MURINE POLYOMAVIRUS | MOUTH-DISEASE VIRUS | MOLECULAR EPIDEMIOLOGY | CODON ALIGNMENTS | BLOOD GROUP ANTIGENS | NORWALK VIRUS-INFECTION | MONOCLONAL-ANTIBODIES | Norovirus - physiology | Amino Acid Sequence | Caliciviridae Infections - prevention & control | Caliciviridae Infections - genetics | Humans | Molecular Sequence Data | Capsid - physiology | Phylogeny | Caliciviridae Infections - transmission | Animals | Binding Sites - physiology | Disease Outbreaks - prevention & control | Mice | Norovirus - genetics | Protein Structure, Tertiary - physiology | Infectious Diseases | Microbiology | Epidemiology | Gastroenteritis | Virology | Carbohydrates | Influenza | Colleges & universities | Writing | Viruses | Ligands | Infections | Genetic algorithms
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