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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 8, pp. 3128 - 3133
Journal Article
Nature Protocols, ISSN 1754-2189, 09/2007, Volume 2, Issue 9, pp. 2245 - 2264
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2017, Volume 7, Issue 1, p. 42728
Chemogenomic profiling is a powerful and unbiased approach to elucidate pharmacological targets and the mechanism of bioactive compounds. Until recently,... 
TARGET | SCREENS | CANCER | MYC | MULTIDISCIPLINARY SCIENCES | NADPH | CRISPR | Clonal deletion | Bioactive compounds | Hypersensitivity | Nicotinamide phosphoribosyltransferase | Genomes | Mammalian cells
Journal Article
by McDonald, E. Robert and de Weck, Antoine and Schlabach, Michael R and Billy, Eric and Mavrakis, Konstantinos J and Hoffman, Gregory R and Belur, Dhiren and Castelletti, Deborah and Frias, Elizabeth and Gampa, Kalyani and Golji, Javad and Kao, Iris and Li, Li and Megel, Philippe and Perkins, Thomas A and Ramadan, Nadire and Ruddy, David A and Silver, Serena J and Sovath, Sosathya and Stump, Mark and Weber, Odile and Widmer, Roland and Yu, Jianjun and Yu, Kristine and Yue, Yingzi and Abramowski, Dorothee and Ackley, Elizabeth and Barrett, Rosemary and Berger, Joel and Bernard, Julie L and Billig, Rebecca and Brachmann, Saskia M and Buxton, Frank and Caothien, Roger and Caushi, Justina X and Chung, Franklin S and Cortés-Cros, Marta and deBeaumont, Rosalie S and Delaunay, Clara and Desplat, Aurore and Duong, William and Dwoske, Donald A and Eldridge, Richard S and Farsidjani, Ali and Feng, JiaJia and Feng, Fei and Flemming, Daisy and Forrester, William and Galli, Giorgio G and Gao, Zhenhai and Gauter, François and Gibaja, Veronica and Haas, Kristy and Hattenberger, Marc and Hood, Tami and Hurov, Kristen E and Jagani, Zainab and Jenal, Mathias and Johnson, Jennifer A and Jones, Michael D and Kapoor, Avnish and Korn, Joshua and Liu, Jilin and Liu, Shumei and Liu, Qiumei and Liu, Yue and Loo, Alice T and Macchi, Kaitlin J and Martin, Typhaine and McAllister, Gregory and Meyer, Amandine and Mollé, Sandra and Pagliarini, Raymond A and Phadke, Tanushree and Repko, Brian and Schouwey, Tanja and Shanahan, Frances and Shen, Qiong and Stamm, Christelle and Stephan, Christine and Stucke, Volker M and Tiedt, Ralph and Varadarajan, Malini and Venkatesan, Kavitha and Vitari, Alberto C and Wallroth, Marco and Weiler, Jan and Zhang, Jing and Mickanin, Craig and Myer, Vic E and Porter, Jeffery A and Lai, Albert and Bitter, Hans and Lees, Emma and Keen, Nicholas and Kauffmann, Audrey and Stegmeier, Frank and Hofmann, Francesco and Schmelzle, Tobias and Sellers, William R
Cell, ISSN 0092-8674, 07/2017, Volume 170, Issue 3, pp. 577 - 592.e10
Journal Article
eLife, ISSN 2050-084X, 05/2016, Volume 5, Issue 2016
The TMPRSS2:ERG gene fusion is common in androgen receptor (AR) positive prostate cancers, yet its function remains poorly understood. From a screen for... 
GENE FUSIONS | COMPLEX | THERAPY | DEPENDENCY | METABOLISM | EPITHELIUM | DNA | TMPRSS2-ERG | BIOLOGY | PROTEIN ARGININE METHYLTRANSFERASES | RESISTANCE | RNA, Small Interfering - genetics | Oncogene Proteins, Fusion - metabolism | Cell Proliferation | Epithelial Cells - metabolism | Humans | Protein Multimerization | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Transcriptional Regulator ERG - metabolism | Protein-Arginine N-Methyltransferases - antagonists & inhibitors | Male | Prostate - metabolism | Prostate - pathology | Base Sequence | Serine Endopeptidases - genetics | Receptors, Androgen - chemistry | Cell Differentiation | Protein Interaction Domains and Motifs | Protein-Arginine N-Methyltransferases - genetics | Protein Structure, Secondary | Signal Transduction | Models, Molecular | Epithelial Cells - pathology | Protein-Arginine N-Methyltransferases - metabolism | Receptors, Androgen - genetics | Oncogene Proteins, Fusion - genetics | Cell Line, Tumor | Protein Binding | Serine Endopeptidases - metabolism | Mutation | Transcriptional Regulator ERG - genetics | Methylation | RNA, Small Interfering - metabolism | Genetic aspects | Cellular signal transduction | Gene expression | Prostate cancer | Health aspects | Biomedical research | Transcription | Genomics | Protein arginine methyltransferase | Epithelium | Gene fusion | Chromatography | ERG gene | Proteins | Androgens | Arginine | DNA methylation | Epigenetics | Scientific imaging | Mass spectrometry | Prostate | Deoxyribonucleic acid--DNA
Journal Article
Nucleic acids research, ISSN 0305-1048, 2006, Volume 34, Issue Database issue, pp. D489 - 494
RNA interference (RNAi) has become a powerful tool for genetic screening in Drosophila. At the Drosophila RNAi Screening Center (DRSC), we are using a library... 
CELLS | DOUBLE-STRANDED-RNA | INTERFERENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | User-Computer Interface | Animals | Gene Library | RNA Interference | Computational Biology | RNA, Double-Stranded - genetics | Databases, Genetic | Software | Genome, Insect | Internet | Drosophila - genetics
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2014, Volume 111, Issue 8, p. 3128
  Defects in epigenetic regulation play a fundamental role in the development of cancer, and epigenetic regulators have recently emerged as promising... 
Cell growth | Chromatin | Epigenetics | Mutation | Cells | Tumors | Cancer
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 02/2014, Volume 111, Issue 8, pp. 3128 - 3128
Defects in epigenetic regulation play a fundamental role in the development of cancer, and epigenetic regulators have recently emerged as promising therapeutic... 
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2006, Volume 34, Issue S1, p. D489
  RNA interference (RNAi) has become a powerful tool for genetic screening in Drosophila. At the Drosophila RNAi Screening Center (DRSC), we are using a... 
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2006, Volume 34, pp. D489 - D494
RNA interference (RNAi) has become a powerful tool for genetic screening in DROSOPHILA: At the Drosophila RNAi Screening Center (DRSC), we are using a library... 
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 01/2006, Volume 34, Issue S1, pp. D489 - D489
RNA interference (RNAi) has become a powerful tool for genetic screening in Drosophila. At the Drosophila RNAi Screening Center (DRSC), we are using a library... 
Journal Article
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