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Journal Article
Chemical Communications, ISSN 1359-7345, 2017, Volume 53, Issue 95, pp. 12798 - 12801
Heme's spin-multiplicity is key in determining the enzymatic function of cytochrome P450 (cytP450). The origin of the low-spin state in ferric P450 is still... 
Cytochrome P-450 Enzyme System - metabolism | Models, Molecular | Cytochrome P-450 Enzyme System - chemistry | Cytochromes b5 - chemistry | Cytochromes b5 - metabolism
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 10/2016, Volume 30, Issue 20, pp. 2310 - 2324
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 11/2019, Volume 55, Issue 89, pp. 13422 - 13425
Cytochrome P450 (cytP450) interacts with two redox partners, cytP450 reductase and cytochrome-b(5), to metabolize substrates. Using NMR, we reveal changes in... 
NANODISCS | NMR | DOMAIN | 2B4 | ROLES | 3A4 | FMN | STATE | BINDING | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 02/2018, Volume 61, Issue 3, pp. 1285 - 1315
A series of calothrixin B (2) analogues bearing substituents at the ‘E’ ring and their corresponding deoxygenated quinocarbazoles lacking quinone unit were... 
ANTHRAQUINONE | CHEMISTRY, MEDICINAL | QUINONES | ACCURATE DOCKING | ELLIPTICINE | DNA TOPOISOMERASE-I | LEISHMANIA-DONOVANI | CYTOTOXICITY | CANCER | DERIVATIVES | BINDING | Index Medicus
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, ISSN 0005-2736, 12/2007, Volume 1768, Issue 12, pp. 3235 - 3259
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 1 - 15
Cytochrome b5 (cytb5) is a membrane protein vital for the regulation of cytochrome P450 (cytP450) metabolism and is capable of electron transfer to many redox... 
Cytochrome c | Cytochrome | Proteins | Cytochrome b | Nuclear magnetic resonance--NMR | Peptides | Cytochrome P450 | Electron transfer | Membrane proteins
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 12/2017, Volume 53, Issue 95, pp. 12798 - 12801
Heme's spin-multiplicity is key in determining the enzymatic function of cytochrome P450 (cytP450). The origin of the low-spin state in ferric P450 is still... 
NMR | COMPLEX | STABILITY | 3A4 | STATE | REDUCTASE | LIGAND | LIPID NANODISCS | RECONSTITUTION | BINDING | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Experimental Hematology, ISSN 0301-472X, 09/2017, Volume 53, pp. S89 - S89
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 05/2007, Volume 129, Issue 21, pp. 6670 - 6670
Cytochrome b(5) (cyt b(5)) is a membrane-anchored electron-carrier protein containing a heme in its soluble domain. It enhances the enzymatic turnover of... 
TOPOLOGY | CATALYSIS | DOMAIN | SPECTROSCOPY | RESOLUTION | SEQUENCE | P4502B4 | BINDING | CHEMISTRY, MULTIDISCIPLINARY | BICELLES
Journal Article
JOURNAL OF PHYSICAL CHEMISTRY B, ISSN 1520-6106, 11/2013, Volume 117, Issue 44, pp. 13851 - 13860
It has been well realized that the dependence of chemical shift anisotropy (CSA) tensors on the amino acid sequence, secondary structure, dynamics, and... 
BACKBONE DYNAMICS | MICROCRYSTALLINE PROTEIN | CROSS-CORRELATED RELAXATION | SOLID-STATE NMR | PROTEIN-STRUCTURE | POWDER PATTERNS | MAGIC-ANGLE | CHEMISTRY, PHYSICAL | DENSITY-FUNCTIONAL THEORY | CYTOCHROME B | MOLECULAR-DYNAMICS SIMULATION
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2013, Volume 3
Microsomal monoxygenase enzymes of the cytochrome-P450 family are found in all biological kingdoms, and play a central role in the breakdown of metabolic as... 
TOPOLOGY | CATALYSIS | SITE | LIPID-BILAYERS | PROTEIN | MULTIDISCIPLINARY SCIENCES | PURIFICATION | P4502B4 | EXPRESSION
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 01/2017, Volume 99, p. 103
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 08/2017, Volume 7
Cytochrome b(5) (cytb(5)) is a membrane protein vital for the regulation of cytochrome P450 (cytP450) metabolism and is capable of electron transfer to many... 
NANODISCS | NMR | PROTEIN | 2B4 | MULTIDISCIPLINARY SCIENCES | BINDING-SITE | REDUCTASE | IDENTIFICATION | INHIBITOR | ASSOCIATION | BICELLES
Journal Article
Scientific Reports, 12/2017, Volume 7, Issue 1, p. 4116
The dynamic protein-protein and protein-ligand interactions of integral bitopic membrane proteins with a single membrane-spanning helix play a plethora of... 
Journal Article
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