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Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e55972
Neuroinflammatory conditions often involve dysfunction of the Blood-Brain Barrier (BBB). Therefore, identifying molecular targets that can maintain barrier... 
MDCK CELLS | ACTIVATION | PROTEIN OCCLUDIN | PERMEABILITY | PHOSPHORYLATION | IMPEDANCE | MULTIDISCIPLINARY SCIENCES | BARRIER FUNCTION | ATROGIN-1 | BETA-CATENIN | EXPRESSION | Endothelium, Vascular - cytology | Humans | Claudin-5 - metabolism | Endothelium, Vascular - drug effects | Glycogen Synthase Kinase 3 beta | Occludin - metabolism | Brain - metabolism | Lithium Chloride - pharmacology | Indoles - pharmacology | Zonula Occludens-1 Protein - metabolism | Tight Junctions - drug effects | Tight Junctions - metabolism | Brain - cytology | Endothelial Cells - metabolism | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Benzazepines - pharmacology | Electric Impedance | Glycogen Synthase Kinase 3 - metabolism | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Brain - drug effects | Endothelial Cells - cytology | Endothelium, Vascular - metabolism | Endothelial Cells - drug effects | Drug abuse | Phosphorylation | Transcription | Laboratories | Gene regulation | Kinases | Inactivation | Retirement planning | Protein turnover | Cell adhesion & migration | Proteins | Signal transduction | β-catenin | Blood-brain barrier | Inhibition | Growth factors | Half life | Deactivation | Glycogen | Glycogen synthase kinase 3 | Cell division | Radioactive half-life | Tightness | Pharmacology | Inflammation | Stability analysis | Permeability | Zonula occludens-1 protein | Endothelial cells | Mutants | Endothelium | Medicine | Pathology | Brain research | Inhibitors | Life extension
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 04/2007, Volume 101, Issue 2, pp. 566 - 576
The blood–brain barrier (BBB) formed by brain microvascular endothelial cells (BMVEC) regulates the passage of molecules and leukocytes in and out of the... 
blood–brain barrier | protein tyrosine kinase | matrix metalloproteinases | protein tyrosine phosphatase | brain endothelial cell | oxidative stress | Protein tyrosine kinase | Oxidative stress | Matrix metalloproteinases | Blood-brain barrier | Brain endothelial cell | Protein tyrosine phosphatase | blood-brain barrier | HUMAN STROKE | FACTOR RECEPTOR TRANSACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOCAL CEREBRAL-ISCHEMIA | VASCULAR-PERMEABILITY | TIGHT JUNCTION | NEUROSCIENCES | SIGNAL-TRANSDUCTION | MULTIPLE-SCLEROSIS | ENDOTHELIAL-CELLS | RHO GTPASES | EXTRACELLULAR-MATRIX | Reactive Oxygen Species - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | Oxidative Stress - physiology | Reactive Oxygen Species - pharmacology | Blood-Brain Barrier - physiopathology | Basement Membrane - pathology | Chemotaxis, Leukocyte - physiology | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Encephalitis - physiopathology | Chemotaxis, Leukocyte - drug effects | Up-Regulation - physiology | Basement Membrane - enzymology | Tight Junctions - metabolism | Encephalitis - enzymology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Cerebral Arteries - physiopathology | Basement Membrane - metabolism | Blood-Brain Barrier - enzymology | Neurodegenerative Diseases - physiopathology | Cerebral Arteries - enzymology | Endothelial Cells - cytology | Matrix Metalloproteinases - metabolism | Endothelial Cells - enzymology | Enzyme Activation - physiology | Neurodegenerative Diseases - enzymology | Neurosciences | Biochemistry | Oxidation | Brain research | Kinases | Neurological disorders
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e77002
Pro-inflammatory activation of vascular endothelium is implicated in pathogenesis of severe conditions including stroke, infarction and sepsis. We have... 
CELL-ADHESION MOLECULE-1 | CATALASE | ACTIVATION | ALLEVIATES OXIDATIVE STRESS | INDUCED APOPTOSIS | MULTIDISCIPLINARY SCIENCES | OXIDASE-DERIVED ROS | NITRIC-OXIDE | NECROSIS-FACTOR-ALPHA | NF-KAPPA-B | SUPEROXIDE-DISMUTASE | Human Umbilical Vein Endothelial Cells | Vasculitis - metabolism | Reactive Oxygen Species - metabolism | Humans | Endothelium, Vascular - drug effects | Male | NF-kappa B - metabolism | Vasculitis - prevention & control | Platelet Endothelial Cell Adhesion Molecule-1 - immunology | Superoxide Dismutase - administration & dosage | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Protective Agents - pharmacology | Superoxides - metabolism | Anti-Inflammatory Agents - administration & dosage | Nitric Oxide Donors - pharmacology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Disease Models, Animal | Drug Synergism | Superoxide Dismutase - chemistry | Animals | Signal Transduction - drug effects | Antibodies, Monoclonal - administration & dosage | Endothelium, Vascular - metabolism | Intracellular Space - metabolism | Vasculitis - drug therapy | Mice | Vascular Cell Adhesion Molecule-1 - metabolism | Cytokines - biosynthesis | Cytokines - pharmacology | Viral antibodies | Cytokines | Ischemia | Anti-inflammatory drugs | Antibodies | Superoxide | Endothelium | Brain | Vascular cell adhesion molecule 1 | Pathogenesis | Superoxide dismutase | Activation | Synergism | Cell adhesion & migration | Cell adhesion molecules | Proteins | Signal transduction | Receptors | Reperfusion | Transfection | Catalase | Cell adhesion | Toll-like receptors | Tumor necrosis factor-TNF | Interception | Immune system | Cerebral infarction | Stroke | Inflammation | Adhesion | Molecular chains | Endothelial cells | White blood cells | Pathology | Signaling | Nitric oxide | Sepsis | Infarction | Brain injury | Endosomes
Journal Article
Journal of neurotrauma, ISSN 0897-7151, 07/2019
Although clinical studies identify traumatic brain injury (TBI) as a risk factor for the development of substance use disorder (SUD), much remains unknown... 
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 1/2015, Volume 35, Issue 1, pp. 28 - 36
Journal Article