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Gastroenterology, ISSN 0016-5085, 05/2018, Volume 154, Issue 6, pp. S-1158 - S-1158
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 05/2018, Volume 46, Issue 5, pp. 485 - 492
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 05/2018, Volume 46, Issue 5, p. 485
There is little known about the impact of nonalcoholic fatty liver disease (NAFLD) on drug metabolism and transport. We examined the pharmacokinetics of oral... 
Fatty liver | Liver diseases | Magnetic resonance imaging | Liver | Body weight | Fibrosis | Drug metabolism | Pharmacology | Regression analysis | Pharmacokinetics | Metabolism | Genotypes
Journal Article
DRUG METABOLISM AND DISPOSITION, ISSN 0090-9556, 05/2018, Volume 46, Issue 5, pp. 485 - 492
There is little known about the impact of nonalcoholic fatty liver disease (NAFLD) on drug metabolism and transport. We examined the pharmacokinetics of oral... 
EFFLUX TRANSPORTERS | DRUG TRANSPORTERS | ACID | MANAGEMENT | METABOLISM | HEALTHY-SUBJECTS | PHARMACOLOGY & PHARMACY | STEATOHEPATITIS | EXPRESSION | DISPOSITION | ATORVASTATIN
Journal Article
by Bhandari, Mohit and Guyatt, Gordon and Tornetta, Paul and Schemitsch, Emil H and Swiontkowski, Marc and Sanders, David and Walter, Stephen D and Gregory Tennent Sanders, David W and Macleod, Mark D and Carey, Timothy and Leitch, Kellie and Bailey, Stuart and Gurr, Kevin and Konito, Ken and Bartha, Charlene and Low, Isolina and MacBean, Leila V and Ramu, Mala and Reiber, Susan and Strapp, Ruth and Tieszer, Christina and Kreder, Hans J and Stephen, David J. G and Axelrod, Terry S and Yee, Albert J. M and Richards, Robin R and Finkelstein, Joel and Ford, Michael and Gofton, Wade and Murnaghan, John and Schatztker, Joseph and Bulmer, Beverly and Conlan, Lisa and Laflamme, G. Yves and Berry, Gregory and Beaumont, Pierre and Ranger, Pierre and Laflamme, Georges-Henri and Gagnon, Sylvain and Malo, Michel and Fernandes, Julio and Poirier, Marie-France and McKee, Michael D and Waddell, James P and Bogoch, Earl R and Daniels, Timothy R and McBroom, Robert R and Vicente, Milena R and Storey, Wendy and Wild, Lisa M and McCormack, Robert and Perey, Bertrand and Goetz, Thomas J and Pate, Graham and Penner, Murray J and Panagiotopoulos, Kostas and Pirani, Shafique and Dommisse, Ian G and Loomer, Richard L and Stone, Trevor and Moon, Karyn and Zomar, Mauri and Webb, Lawrence X and Teasdall, Robert D and Birkedal, John Peter and Martin, David Franklin and Ruch, David S and Kilgus, Douglas J and Pollock, David C and Harris, Mitchel Brion and Wiesler, Ethan Ron and Ward, William G and Shilt, Jeffrey Scott and Koman, Anew L and Poehling, Gary G and Kulp, Brenda and Creevy, William R and Stein, Anew B and Bono, Christopher T and Einhorn, Thomas A and Brown, T. Desmond and Pacicca, Donna and Sledge, John B and Foster, Timothy E and Voloshin, Ilva and Bolton, Jill and Carlisle, Hope and Shaughnessy, Lisa and Obremskey, William T and LeCroy, C. Michael and Meinberg, Eric G and Messer, Terry M and Craig, William L and Dirschl, Douglas R and Caudle, Robert and Harris, Tim and Elhert, Kurt and Hage, William and Jones, Robert and Pieahita, Luis and ... and SPRINT Investigators and Study to Prospectively Evaluate Reamed Intramedullary Nails in Patients with Tibial Fractures Investigators
Journal of bone and joint surgery. American volume, ISSN 0021-9355, 2008, Volume 90A, Issue 12, pp. 2567 - 2578
Journal Article
by Obremskey, William and Agel, Julie and Archer, Kristin and To, Philip and Tornetta, Paul and Bhandari, Mohit and Guyatt, Gordon and Sanders, David W and Schemitsch, Emil H and Swiontkowski, Marc and Walter, Stephen and Sprague, Sheila and Heels-Ansdell, Diane and Buckingham, Lisa and Leece, Pamela and Viveiros, Helena and Mignott, Tashay and Ansell, Natalie and Sidorkewicz, Natalie and Bombardier, Claire and Berlin, Jesse A and Bosse, Michael and Browner, Bruce and Gillespie, Brenda and Jones, Alan and O'Brien, Peter and Poolman, Rudolf and Macleod, Mark D and Carey, Timothy and Leitch, Kellie and Bailey, Stuart and Gurr, Kevin and Konito, Ken and Bartha, Charlene and Low, Isolina and MacBean, Leila V and Ramu, Mala and Reiber, Susan and Strapp, Ruth and Tieszer, Christina and Kreder, Hans J and Stephen, David J. G and Axelrod, Terry S and Yee, Albert J. M and Richards, Robin R and Finkelstein, Joel and Gofton, Wade and Murnaghan, John and Schatztker, Joseph and Ford, Michael and Bulmer, Beverly and Conlan, Lisa and Laflamme, G. Yves and Berry, Gregory and Beaumont, Pierre and Ranger, Pierre and Laflamme, Georges-Henri and Gagnon, Sylvain and Malo, Michel and Fernandes, Julio and Poirier, Marie-France and McKee, Michael D and Waddell, James P and Bogoch, Earl R and Daniels, Timothy R and McBroom, Robert R and Vicente, Milena R and Storey, Wendy and Wild, Lisa M and McCormack, Robert and Perey, Bertrand and Goetz, Thomas J and Pate, Graham and Penner, Murray J and Panagiotopoulos, Kostas and Pirani, Shafique and Dommisse, Ian G and Loomer, Richard L and Stone, Trevor and Moon, Karyn and Zomar, Mauri and Webb, Lawrence X and Teasdall, Robert D and Birkedal, John Peter and Martin, David Franklin and Ruch, David S and Kilgus, Douglas J and Pollock, David C and Harris, Mitchel Brion and Wiesler, Ethan Ron and Ward, William G and Shilt, Jeffrey Scott and Koman, Anew L and Poehling, Gary G and Kulp, Brenda and Creevy, William R and Stein, Anew B and Bono, Christopher T and Einhorn, Thomas A and Brown, T. Desmond and ... and SPRINT Investigators
Journal of orthopaedic trauma, ISSN 0890-5339, 2016, Volume 30, Issue 3, pp. 135 - 141
Journal Article
by Bhandari, Mohit and Tornetta, Paul and Rampersad, Shelly-Ann and Sprague, Sheila and Heels-Ansdell, Diane and Sanders, David W and Schemitsch, Emil H and Swiontkowski, Marc and Walter, Stephen and Guyatt, Gordon and Buckingham, Lisa and Leece, Pamela and Viveiros, Helena and Mignott, Tashay and Ansell, Natalie and Sidorkewicz, Natalie and Agel, Julie and Bombardier, Claire and Berlin, Jesse A and Bosse, Michael and Browner, Bruce and Gillespie, Brenda and O'Brien, Peter and Poolman, Rudolf and Macleod, Mark D and Carey, Timothy and Leitch, Kellie and Bailey, Stuart and Gurr, Kevin and Konito, Ken and Bartha, Charlene and Low, Isolina and MacBean, Leila V and Ramu, Mala and Reiber, Susan and Strapp, Ruth and Tieszer, Christina and Kreder, Hans and Stephen, David J. G and Axelrod, Terry S and Yee, Albert J. M and Richards, Robin R and Finkelstein, Joel and Holtby, Richard M and Cameron, Hugh and Cameron, John and Gofton, Wade and Murnaghan, John and Schatztker, Joseph and Bulmer, Beverly and Conlan, Lisa and Laflamme, Yves and Berry, Gregory and Beaumont, Pierre and Ranger, Pierre and Laflamme, Georges-Henri and Jodoin, Alain and Renaud, Eric and Gagnon, Sylvain and Maurais, Gilles and Malo, Michel and Fernandes, Julio and Latenesse, Kim and Poirier, Marie-France and Daigneault, Gina and McKee, Michael M and Waddell, James P and Bogoch, Earl R and Daniels, Timothy R and McBroom, Robert R and Vicente, Milena R and Storey, Wendy and Wild, Lisa M and McCormack, Robert and Perey, Bertrand and Goetz, Thomas J and Pate, Graham and Penner, Murray J and Panagiotopoulos, Kostas and Pirani, Shafique and Dommisse, Ian G and Loomer, Richard L and Stone, Trevor and Moon, Karyn and Zomar, Mauri and Webb, Lawrence X and Teasdall, Robert D and Birkedal, John Peter and Martin, David Franklin and Ruch, David S and Kilgus, Douglas J and Pollock, David C and Harris, Mitchel Brion and Wiesler, Ethan Ron and Ward, William G and Shilt, Jeffrey Scott and Koman, Anew L and Poehling, Gary G and Kulp, Brenda and Creevy, William R and ... and SPRINT Investigators
Journal of orthopaedic trauma, ISSN 0890-5339, 2013, Volume 27, Issue 4, pp. 183 - 188
Inadequate sample size and power in randomized trials can result in misleading findings. This study demonstrates the effect of sample size in a large clinical... 
intramedullary nailing | sample size | tibia fracture | SPORT SCIENCES | RANDOMIZED-TRIALS | POWER | ORTHOPEDICS | Young Adult | Tibial Fractures - surgery | Fracture Fixation, Intramedullary - methods | Sample Size | Bone Nails | Fractures, Closed - surgery | Humans | Middle Aged | Adult | Female | Male | Fractures, Open - surgery
Journal Article
by Lin, Carol Alice and Bhandari, Mohit and Guyatt, Gordon and Walter, Stephen D and Schemitsch, Emil H and Swiontkowski, Marc and Sanders, David and Tornetta, Paul and Sanders, David W and Walter, Stephen and Sprague, Sheila and Heels-Ansdell, Diane and Buckingham, Lisa and Leece, Pamela and Viveiros, Helena and Mignott, Tashay and Ansell, Natalie and Sidorkewicz, Natalie and Agel, Julie and Bombardier, Claire and Berlin, Jesse A and Bosse, Michael and Browner, Bruce and Gillespie, Brenda and Jones, Alan and O'Brien, Peter and Poolman, Rudolf and Macleod, Mark D and Carey, Timothy and Leitch, Kellie and Bailey, Stuart and Gurr, Kevin and Konito, Ken and Bartha, Charlene and Low, Isolina and MacBean, Leila V and Ramu, Mala and Reiber, Susan and Strapp, Ruth and Tieszer, Christina and Kreder, Hans J and Stephen, David J. G and Axelrod, Terry S and Yee, Albert J. M and Richards, Robin R and Finkelstein, Joel and Gofton, Wade and Murnaghan, John and Schatztker, Joseph and Ford, Michael and Bulmer, Beverly and Conlan, Lisa and Laflamme, G. Yves and Berry, Gregory and Beaumont, Pierre and Ranger, Pierre and Laflamme, Georges-Henri and Gagnon, Sylvain and Malo, Michel and Fernandes, Julio and Poirier, Marie-France and McKee, Michael D and Waddell, James P and Bogoch, Earl R and Daniels, Timothy R and McBroom, Robert R and Vicente, Milena R and Storey, Wendy and Wild, Lisa M and McCormack, Robert and Perey, Bertrand and Goetz, Thomas J and Pate, Graham and Penner, Murray J and Panagiotopoulos, Kostas and Pirani, Shafique and Dommisse, Ian G and Loomer, Richard L and Stone, Trevor and Moon, Karyn and Zomar, Mauri and Webb, Lawrence X and Teasdall, Robert D and Birkedal, John Peter and Martin, David Franklin and Ruch, David S and Kilgus, Douglas J and Pollock, David C and Harris, Mitchel Brion and Wiesler, Ethan Ron and Ward, William G and Shilt, Jeffrey Scott and Koman, Anew L and Poehling, Gary G and Kulp, Brenda and Creevy, William R and Stein, Anew B and Bono, Christopher T and Einhorn, Thomas A and Brown, T. Desmond and ... and SPRINT Investigators
Journal of orthopaedic trauma, ISSN 0890-5339, 2016, Volume 30, Issue 3, pp. 156 - 161
Journal Article
Journal of Clinical Epidemiology, ISSN 0895-4356, 2009, Volume 62, Issue 11, pp. 1210 - 1217
Journal Article
by Busse, Jason W and Bhandari, Mohit and Guyatt, Gordon H and Heels-Ansdell, Diane and Kulkarni, Abhaya V and Mandel, Scott and Sanders, David and Schemitsch, Emil and Swiontkowski, Mark and Tornetta, Paul and Wai, Eugene and Walter, Stephen D and Guyatt, Gordon and Sanders, David W and Schemitsch, Emil H and Swiontkowski, Marc and Walter, Stephen and Sprague, Sheila and Buckingham, Lisa and Leece, Pamela and Viveiros, Helena and Mignott, Tashay and Ansell, Natalie and Sidorkewicz, Natalie and Agel, Julie and Bombardier, Claire and Berlin, Jesse A and Bosse, Michael and Browner, Bruce and Gillespie, Brenda and Jones, Alan and O'Brien, Peter and Poolman, Rudolf and Macleod, Mark D and Carey, Timothy and Leitch, Kellie and Bailey, Stuart and Gurr, Kevin and Bartha, Charlene and Low, Isolina and MacBean, Leila V and Ramu, Mala and Reiber, Susan and Strapp, Ruth and Tieszer, Christina and Kreder, Hans J and Stephen, David J. G and Axelrod, Terry S and Yee, Albert J. M and Richards, Robin R and Finkelstein, Joel and Gofton, Wade and Murnaghan, John and Schatztker, Joseph and Ford, Michael and Bulmer, Beverly and Conlan, Lisa and Laflamme, G. Yves and Berry, Gregory and Beaumont, Pierre and Ranger, Pierre and Laflamme, Georges-Henri and Gagnon, Sylvain and Malo, Michel and Fernandes, Julio and Poirier, Marie-France and McKee, Michael D and Waddell, James P and Bogoch, Earl R and Daniels, Timothy R and McBroom, Robert R and Vicente, Milena R and Storey, Wendy and M, Lisa and McCormack, Robert and Perey, Bertrand and Goetz, Thomas J and Pate, Graham and Penner, Murray J and Panagiotopoulos, Kostas and Pirani, Shafique and Dommisse, Ian G and Loomer, Richard L and Stone, Trevor and Moon, Karyn and Zomar, Mauri and Webb, Lawrence X and Teasdall, Robert D and Birkedal, John Peter and Martin, David Franklin and Ruch, David S and Kilgus, Douglas J and Pollock, David C and Harris, Mitchel Brion and Wiesler, Ethan Ron and Ward, William G and Shilt, Jeffrey Scott and Koman, Anew L and Poehling, Gary G and Kulp, Brenda and ... and SPRINT Investigators and Medically Unexplained Syndromes and SPRINT Investigators & the Medically Unexplained Syndromes Study Group
Journal of orthopaedic trauma, ISSN 0890-5339, 2012, Volume 26, Issue 6, pp. 370 - 378
Journal Article