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Journal Article
Nature Communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 1 - 15
The beta-site APP cleaving enzyme 1 (BACE1) is known primarily for its initial cleavage of the amyloid precursor protein (APP), which ultimately leads to the... 
Degradation | b-Site APP cleaving enzyme 1 | Peptides | Neurodegeneration | Cognitive ability | Cortex | Health risks | Dementia disorders | Cerebrospinal fluid | Alzheimer's disease | Amyloid precursor protein | Dementia
Journal Article
JAMA Neurology, ISSN 2168-6149, 05/2018, Volume 75, Issue 5, p. 536
The introduction of positron emission tomography (PET) tracers that can identify paired helical filaments of hyperphosphorylated tau (ie, neurofibrillary... 
Nuclear medicine | Neurodegenerative diseases | Cognitive ability | Positron emission | Emissions | Neurofibrillary tangles | Tau protein | Filaments | Tomography | Biomarkers | Alzheimers disease | Alzheimer's disease | Positron emission tomography | Tracers
Journal Article
Alzheimer's & Dementia, ISSN 1552-5260, 07/2018, Volume 14, Issue 7S_Part_4, pp. P276 - P276
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P276 - P276
Journal Article
Journal Article
Annals of Clinical and Translational Neurology, ISSN 2328-9503, 12/2018, Volume 5, Issue 12, pp. 1492 - 1504
Objectives Clinical trials for progressive neurodegenerative disorders such as Alzheimer's Disease and Amyotrophic Lateral Sclerosis have been hindered due to... 
TURNOVER | INCLUSIONS | REDUCTION | TDP-43 | CLINICAL-TRIALS | IN-VIVO | AMYOTROPHIC-LATERAL-SCLEROSIS | ANTISENSE OLIGONUCLEOTIDES | NEUROSCIENCES | AGGREGATION | CLINICAL NEUROLOGY | SOD1 | Proteins | Alzheimers disease | Protein synthesis
Journal Article
Acta Neuropathologica Communications, ISSN 2051-5960, 12/2018, Volume 6, Issue 1, pp. 1 - 19
Accumulating evidence demonstrating higher cerebrospinal fluid (CSF) α-synuclein (αSyn) levels and αSyn pathology in the brains of Alzheimer’s disease (AD)... 
Studies | Brain | Pathology | Mutation | Biomarkers | APOEε4 | Alzheimer’s disease | alpha-synuclein | Mild cognitive impairment
Journal Article
Frontiers in Neurology, ISSN 1664-2295, 03/2018, Volume 9
Alzheimer’s disease (AD) is a neurodegenerative disorder with clinical manifestations of progressive memory decline and loss of executive function and... 
plaque dynamics | stable isotope tracer | Alzheimer’s disease | Aβ plaques | SILK–SIMS
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, p. 38187
Journal Article
Annals of Neurology, ISSN 0364-5134, 01/2018, Volume 83, Issue 1, pp. 197 - 204
Sleep disturbances are associated with future risk of Alzheimer disease. Disrupted sleep increases soluble amyloid β, suggesting a mechanism for sleep... 
DEMENTIA | DEPOSITION | DYNAMICS | SLOW-WAVE SLEEP | RISK | CENTRAL-NERVOUS-SYSTEM | OLDER WOMEN | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | CLINICAL NEUROLOGY | AGE | Deprivation | Neurodegenerative diseases | Health risks | Risk | Cerebrospinal fluid | Leucine | Disease control | Catheters | Sleep deprivation | Sleep | Sodium | Disturbances | Kinetics | Alzheimer's disease
Journal Article
Annals of Neurology, ISSN 0364-5134, 06/2016, Volume 79, Issue 6, pp. 929 - 939
Journal Article
Brain, ISSN 0006-8950, 04/2018, Volume 141, Issue 4, pp. 1186 - 1200
The neural basis of reserve capacity in Alzheimer's disease is yet to be fully determined. Franzmeier et al. show that greater left frontal hub connectivity... 
IMAGING BIOMARKERS | memory | dementia biomarkers | LOW-FREQUENCY | OLDER-ADULTS | cognitive reserve | FUNCTIONAL CONNECTIVITY | HIPPOCAMPAL FUNCTION | resting state connectivity | NEUROSCIENCES | CLINICAL NEUROLOGY | BRAIN RESERVE | MEMORY VARIANCE | CORTICAL HUBS | PHYSICAL-ACTIVITY | Alzheimer's disease | WORKING-MEMORY
Journal Article