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Lancet, The, ISSN 0140-6736, 2017, Volume 389, pp. S15 - S15
Abstract Background Organ fibrosis is a major cause of global mortality. Few medical therapies are available to treat this condition. We have previously... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | Liver diseases | Analysis | Liver | Therapeutics | Homeopathy | Materia medica and therapeutics | RNA sequencing | Mortality | Collagen | Carbon tetrachloride | Low density lipoproteins | Macrophages
Journal Article
Nature, ISSN 0028-0836, 2016, Volume 538, Issue 7625, pp. 392 - 396
Journal Article
Nature Immunology, ISSN 1529-2908, 03/2015, Volume 16, Issue 4, pp. 386 - 396
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2015, Volume 125, Issue 2, pp. 501 - 520
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 281 - 12
Macrophages serve multiple functions including immune regulation, morphogenesis, tissue homeostasis and healing reactions. The current paradigm holds that... 
CELLS | ORIGIN | MICROGLIA | ROLES | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | ONTOGENY | MONOCYTES | DIFFERENTIATION | Phenotypes | Immunoregulation | Liver | Fetuses | Scavenging | Stroma | Homeostasis | Mammary glands | Mapping | Macrophages | Tissues | White blood cells | Morphogenesis | Yolk sac | Monocytes | Depletion | Cell fate | Cattle | Bone marrow | Mammary gland | Gene mapping | Localization | Yolk | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, pp. e0141974 - e0141974
The genetic targeting of mouse models has given insight into complex processes. However, phenotypes of genetically targeted mice are susceptible to artifacts... 
RHEUMATOID-ARTHRITIS | ENCEPHALOMYELITIS | COLLAGEN-INDUCED ARTHRITIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | NADPH-OXIDASE | REACTIVE OXYGEN | DBA/1 MICE | AUTOIMMUNITY | CHRONIC GRANULOMATOUS-DISEASE | MULTIDISCIPLINARY SCIENCES | SEVERITY | Cell Line | Gene Targeting | Arthritis, Experimental - genetics | Gene Expression Regulation - immunology | NADPH Oxidases - immunology | Male | Arthritis, Experimental - immunology | NADPH Oxidase 2 | STAT1 Transcription Factor - immunology | Membrane Glycoproteins - genetics | Mice, Knockout | Arthritis, Experimental - pathology | Phenotype | Animals | Reactive Oxygen Species - immunology | Gene Deletion | NADPH Oxidases - genetics | Female | Mice | Membrane Glycoproteins - immunology | Polymorphism, Single Nucleotide - immunology | Care and treatment | Systemic lupus erythematosus | Patient outcomes | Development and progression | Genetic aspects | Genetic engineering | Research | Single nucleotide polymorphisms | Reactive oxygen species | Animal models | Transcription | Disease | Laboratories | Genes | Genomes | Arthritis | Single-nucleotide polymorphism | Gene deletion | Gene polymorphism | NAD(P)H oxidase | Proteins | Phagocytes | Immunology | Clonal deletion | Rodents | CYBB protein | Deletion | Physiology | Stat1 protein | Lupus | Inflammation | Artifacts | Collagen | Interferon | Gene manipulation | Mutation | Females | Autoimmune diseases | Polymorphism | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2016, Volume 113, Issue 38, pp. 10643 - 10648
Afferent lymphatic vessels bring antigens and diverse populations of leukocytes to draining lymph nodes, whereas efferent lymphatics allow only lymphocytes and... 
Lymphatics | Cell traffic | Lymphocytes | Endothelium | endothelium | MACROPHAGE SCAVENGER RECEPTORS | L-SELECTIN | lymphocytes | LYMPHOCYTE BINDING | ENDOMUCIN | NODE | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | cell traffic | MANNOSE RECEPTOR | INFLAMMATION | HIGH ENDOTHELIAL VENULES | lymphatics | SIALOMUCIN | Antigens | Leucocytes | Lymphatic system | Gene expression | Medical immunity | Index Medicus | Biological Sciences
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 7, pp. e0159010 - e0159010
Idiopathic pulmonary fibrosis (IPF) is characterized by activation and injury of epithelial cells, the accumulation of connective tissue and changes in the... 
RECOMBINATION | TO-MESENCHYMAL TRANSITION | ANTAGONIST | MIGRATION INHIBITORY FACTOR | BONE MORPHOGENETIC PROTEIN | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION PATTERNS | IN-VIVO | GROWTH | TRANSGENIC MICE | Intercellular Signaling Peptides and Proteins - analysis | Cell Line | Up-Regulation | Idiopathic Pulmonary Fibrosis - genetics | Lung - pathology | Silicon Dioxide - immunology | Humans | Intercellular Signaling Peptides and Proteins - genetics | Mice, Transgenic | Idiopathic Pulmonary Fibrosis - immunology | Interferons - immunology | Lymphocytes - pathology | Animals | Chemokine CXCL10 - analysis | Lymphocytes - immunology | Chemokine CXCL10 - immunology | Idiopathic Pulmonary Fibrosis - pathology | Mice | Lung - immunology | Pulmonary fibrosis | Gene expression | Epithelial cells | Analysis | Risk factors | Heart | Disease | Mesenchyme | Laboratories | Crosstalk | Lung | Critical care | Lymphocytes T | Silica | Silicon dioxide | Recruitment | Proteins | Connective tissues | Gremlin protein | Toxicology | Transgenic animals | Bioaccumulation | Bronchoalveolar lavage | Rodents | Fibroblasts | Bone morphogenetic proteins | Occupational health | Alveoli | Kidneys | Cytokines | Lung diseases | Cloning | Transgenic mice | Bronchus | Protein C | Inflammation | Circadian rhythm | Medicine | Surfactant protein C | Hospitals | DNA microarrays | Lungs | CXCL10 protein | Fibrosis | Interferon | Molecular biology | Chemokines | Index Medicus
Journal Article
FASEB Journal, ISSN 0892-6638, 06/2017, Volume 31, Issue 6, pp. 2477 - 2491
Journal Article
European Journal of Immunology, ISSN 0014-2980, 02/2015, Volume 45, Issue 2, pp. 562 - 573
CD73/ecto‐5′‐nucleotidase is a key enzyme in the regulation of purinergic signaling and inflammatory reactions. It hydrolyzes extracellular AMP into adenosine,... 
adenosine | endothelial cells | purinergic signaling | lymphatics | permeability | Adenosine | Lymphatics | Permeability | Endothelial cells | Purinergic signaling | CD73 | ECTONUCLEOTIDASES | IMMUNOLOGY | HYPOXIA | IDENTIFICATION | ADENOSINE PRODUCTION | INFLAMMATION | IN-VIVO | CD39 | UP-REGULATION | T-CELLS | Endothelium, Vascular - cytology | 5'-Nucleotidase - genetics | CD8-Positive T-Lymphocytes - cytology | Humans | Capillary Permeability - immunology | Antigens, CD19 - genetics | 5'-Nucleotidase - deficiency | 5'-Nucleotidase - immunology | CD8-Positive T-Lymphocytes - metabolism | Endothelium, Lymphatic - metabolism | B-Lymphocytes - metabolism | Receptors, Purinergic P1 - immunology | Antigens, CD19 - immunology | Endothelium, Vascular - immunology | B-Lymphocytes - cytology | Gene Expression | Receptors, Purinergic P1 - genetics | Signal Transduction | Adenosine - immunology | Adenosine Monophosphate - metabolism | Endothelial Cells - metabolism | Endothelium, Lymphatic - immunology | Adenosine Monophosphate - immunology | Immunity, Innate | Organ Specificity | Mice, Knockout | Endothelial Cells - immunology | Animals | B-Lymphocytes - immunology | Endothelial Cells - cytology | Endothelium, Vascular - metabolism | Adenosine - metabolism | Endothelium, Lymphatic - cytology | Mice | CD8-Positive T-Lymphocytes - immunology | Neovascularization, Physiologic | Rodents | Blood | Immune system | Index Medicus
Journal Article
Journal Article