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The lancet oncology, ISSN 1470-2045, 01/2017, Volume 18, Issue 1, pp. 75 - 87
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 12/2013, Volume 31, Issue 35, pp. 4453 - 4461
Journal Article
by Coleman, Robert L and Oza, Amit M and Lorusso, Domenica and Aghajanian, Carol and Oaknin, Ana and Dean, Andrew and Colombo, Nicoletta and Weberpals, Johanne I and Clamp, Andrew and Scambia, Giovanni and Leary, Alexandra and Holloway, Robert W and Gancedo, Margarita Amenedo and Fong, Peter C and Goh, Jeffrey C and O'Malley, David M and Armstrong, Deborah K and Garcia-Donas, Jesus and Swisher, Elizabeth M and Floquet, Anne and Konecny, Gottfried E and McNeish, Iain A and Scott, Clare L and Cameron, Terri and Maloney, Lara and Isaacson, Jeff and Goble, Sandra and Grace, Caroline and Harding, Thomas C and Raponi, Mitch and Sun, James and Lin, Kevin K and Giordano, Heidi and Ledermann, Jonathan A and Buck, M and Dean, A and Friedlander, M L and Goh, J C and Harnett, P and Kichenadasse, G and Scott, C L and Denys, H and Dirix, L and Vergote, I and Elit, L and Ghatage, P and Oza, A M and Plante, M and Provencher, D and Weberpals, J I and Welch, S and Floquet, A and Gladieff, L and Joly, F and Leary, A and Lortholary, A and Lotz, J and Medioni, J and Tredan, O and You, B and El-Balat, A and Hänle, C and Krabisch, P and Neunhöffer, T and Pölcher, M and Wimberger, P and Amit, A and Kovel, S and Leviov, M and Safra, T and Shapira-Frommer, R and Stemmer, S and Bologna, A and Colombo, N and Lorusso, D and Pignata, S and Sabbatini, R F and Scambia, G and Tamberi, S and Zamagni, C and Fong, P C and O'Donnell, A and Gancedo, M Amenedo and Herraez, A Casado and Garcia-Donas, J and Guerra, E M and Oaknin, A and Palacio, I and Romero, I and Sanchez, A and Banerjee, S N and Clamp, A and Drew, Y and Gabra, H G and Jackson, D and Ledermann, J A and McNeish, I A and Parkinson, C and Powell, M and Aghajanian, C and ... and ARIEL3 investigators and ARIEL3 Investigators
The Lancet (British edition), ISSN 0140-6736, 10/2017, Volume 390, Issue 10106, pp. 1949 - 1961
Rucaparib, a poly(ADP-ribose) polymerase inhibitor, has anticancer activity in recurrent ovarian carcinoma harbouring a BRCA mutation or high percentage of... 
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Double-Blind Method | Follow-Up Studies | Risk Assessment | Humans | Middle Aged | Ovarian Neoplasms - pathology | Neoplasm Recurrence, Local - drug therapy | Survival Rate | Treatment Outcome | Ovarian Neoplasms - mortality | Neoplasm Recurrence, Local - mortality | Indoles - administration & dosage | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Neoplasm Recurrence, Local - pathology | Disease-Free Survival | Maintenance Chemotherapy - methods | Internationality | Ovarian Neoplasms - therapy | Female | Aged | Molecular Targeted Therapy - methods | Clinical trials | Care and treatment | Carcinoma | Drug therapy | Ovarian cancer | Cancer | Analysis | Chemotherapy | Ovarian carcinoma | Platinum | Biomarkers | Mutation | Cancer therapies | Evidence-based medicine | Tumors | Homologous recombination | Central nervous system | Poly(ADP-ribose) | Homology | Genomes | Fallopian tube | Anticancer properties | Metastases | Homologous recombination repair | Randomization | Pain | Motivation | Ribose | Hemoglobin | Alanine | Anemia | Poly(ADP-ribose) polymerase | Adenosine diphosphate | Breast cancer | Patients | Survival | Heterozygosity | Abdomen | Inhibitors | Point mutation | Loss of heterozygosity | Antitumor activity | Aspartate aminotransferase | Peritoneum | Index Medicus | Abridged Index Medicus
Journal Article
The New England journal of medicine, ISSN 1533-4406, 04/2015, Volume 372, Issue 18, pp. 1700 - 1709
Patients with non–small-cell lung cancer and mutated epidermal growth factor receptors who develop resistance to EGFR inhibitors through a particular mutation... 
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Lung Neoplasms - drug therapy | Humans | Middle Aged | ErbB Receptors - genetics | Lung Neoplasms - pathology | Male | Antineoplastic Agents - administration & dosage | Protein Kinase Inhibitors - adverse effects | Acrylamides - pharmacokinetics | Dose-Response Relationship, Drug | Hyperglycemia - chemically induced | Antineoplastic Agents - adverse effects | Female | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Protein Kinase Inhibitors - pharmacokinetics | ErbB Receptors - antagonists & inhibitors | Carcinoma, Non-Small-Cell Lung - genetics | Pyrimidines - administration & dosage | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Acrylamides - administration & dosage | Pyrimidines - adverse effects | Pyrimidines - pharmacokinetics | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Acrylamides - adverse effects | Clinical trials | Care and treatment | Usage | Diagnosis | Lung cancer, Non-small cell | Hyperglycemia | Chemotherapy | Epidermal growth factor | Inhibitor drugs | Epidermal growth factor receptors | Lung cancer | Genes | Non-small cell lung carcinoma | Antitumor activity | Pharmacokinetics | Patients | Index Medicus | Abridged Index Medicus
Journal Article
Cancer research (Chicago, Ill.), ISSN 1538-7445, 08/2006, Volume 66, Issue 15, pp. 7466 - 7472
Journal Article
Clinical cancer research, ISSN 1557-3265, 06/2018, Volume 24, Issue 12, pp. 2944 - 2950
Purpose: About 60% of non-small cell lung cancer (NSCLC) patients develop resistance to targeted epidermal growth factor receptor (EGFR) inhibitor therapy... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Tyrosine | Epidermal growth factor receptors | Laboratories | Lung cancer | Non-small cell lung carcinoma | Ribonucleic acid--RNA | Patients | Sensitivity | Epidermal growth factor | Biopsy | Experimental design | Alleles | Mutation | Protein-tyrosine kinase | Deoxyribonucleic acid--DNA | Cancer | Tumors | Index Medicus
Journal Article
Cancer discovery, ISSN 2159-8274, 07/2015, Volume 5, Issue 7, pp. 713 - 723
Rociletinib is a third-generation EGFR inhibitor active in lung cancers with T790M, the gatekeeper mutation underlying most first-generation EGFR drug... 
Journal Article