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Free Radical Biology and Medicine, ISSN 0891-5849, 05/2018, Volume 120, pp. S1 - S1
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 05/2018, Volume 120, p. S1
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.freeradbiomed.2018.04.012 
Gene expression
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2006, Volume 281, Issue 22, pp. 15215 - 15226
Studies of gene regulation by oxygen have revealed novel signal pathways that regulate the hypoxia-inducible factor (HIF) transcriptional system through... 
ACTIVATION | INDUCIBLE FACTOR-1 HIF-1 | PROLYL HYDROXYLATION | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | RENAL-CELL-CARCINOMA | GROWTH-FACTOR | FACTOR (HIF)-1-ALPHA | UP-REGULATION | TUMOR-GROWTH | NEGATIVE REGULATOR
Journal Article
NATURE REVIEWS NEPHROLOGY, ISSN 1759-5061, 10/2019, Volume 15, Issue 10, pp. 641 - 659
Studies of the regulation of erythropoietin (EPO) production by the liver and kidneys, one of the classical physiological responses to hypoxia, led to the... 
FACTOR-INHIBITING-HIF | PROLYL HYDROXYLASE INHIBITOR | OXYGEN-SENSING PATHWAY | INDUCIBLE-FACTOR-ALPHA | ERYTHROPOIETIN-PRODUCING CELLS | UROLOGY & NEPHROLOGY | TUMOR-SUPPRESSOR PROTEIN | ACUTE-RENAL-FAILURE | CHRONIC KIDNEY-DISEASE | ANKYRIN REPEAT DOMAIN | TRANSCRIPTIONAL RESPONSE
Journal Article
Science, ISSN 0036-8075, 4/2009, Volume 324, Issue 5924, pp. 192 - 194
Mutations in a gene that encodes a metabolic enzyme have been linked to certain brain tumors, but is the gene a tumor suppressor or an oncogene? 
Isocitrates | Tricarboxylic acid cycle | Enzymes | Energy metabolism | Genes | Glioblastoma | Policy Forum | Genetic mutation | Oncogenes | Tumors | Cancer | GLIOMAS | IDH1 | MULTIDISCIPLINARY SCIENCES | RISK | MUTATIONS | TUMOR SUPPRESSORS | CANCER | DEPENDENT ISOCITRATE DEHYDROGENASE
Journal Article
Cancer Research, ISSN 0008-5472, 04/2003, Volume 63, Issue 8, pp. 1764 - 1768
Hypoxia-inducible factor (HIF) plays an important role in determining patterns of gene expression in cancer. HIF is down-regulated in oxygenated cells by a... 
VITAMIN-C | HUMAN PROSTATE-CANCER | PROTEIN | GENE | HIF | FACTOR-1-ALPHA | ONCOLOGY | PROLYL HYDROXYLATION | EXPRESSION | LINES | FAMILY | Neoplasms - metabolism | Prostatic Neoplasms - metabolism | Vascular Endothelial Growth Factor A | Cell Hypoxia - physiology | Lymphokines - secretion | Vascular Endothelial Growth Factors | Humans | Transcriptional Activation - drug effects | Intercellular Signaling Peptides and Proteins - biosynthesis | Male | Hypoxia-Inducible Factor 1, alpha Subunit | Breast Neoplasms - metabolism | Endothelial Growth Factors - secretion | Procollagen-Proline Dioxygenase - metabolism | RNA, Messenger - biosynthesis | Adenocarcinoma - metabolism | Lymphokines - genetics | Neoplasms - genetics | Ferrous Compounds - pharmacology | Female | Ovarian Neoplasms - metabolism | Intercellular Signaling Peptides and Proteins - secretion | Lymphokines - biosynthesis | Tumor Cells, Cultured | Monosaccharide Transport Proteins - genetics | RNA, Messenger - genetics | Intercellular Signaling Peptides and Proteins - genetics | Glucose Transporter Type 1 | Transcription Factors - biosynthesis | Endothelial Growth Factors - biosynthesis | Transcription Factors - genetics | Monosaccharide Transport Proteins - biosynthesis | Endothelial Growth Factors - genetics | Ascorbic Acid - pharmacology | Transferrin - pharmacology
Journal Article
Cancer and Metabolism, ISSN 2049-3002, 02/2014, Volume 2, Issue 1, pp. 3 - 3
Both tumor hypoxia and dysregulated metabolism are classical features of cancer. Recent analyses have revealed complex interconnections between oncogenic... 
Hypoxia | HIF | Metabolism | Cancer
Journal Article
JAMA, ISSN 0098-7484, 09/2016, Volume 316, Issue 12, pp. 1252 - 1253
The 2016 Albert Lasker Basic Medical Research Award has been presented to William G. Kaelin, Peter J. Ratcliffe, and Gregg L. Semenza for the discovery and... 
ENHANCER | MEDICINE, GENERAL & INTERNAL | PROTEIN | HIF | HYPOXIA | HYDROXYLATION | Awards and Prizes | Homeostasis | Animals | Humans | Oxygen - metabolism | Cell Physiological Phenomena | Oxygen | Regulation | Cobalt
Journal Article
by Taylor, Jenny C and Martin, Hilary C and Lise, Stefano and Broxholme, John and Cazier, Jean-Baptiste and Rimmer, Andy and Kanapin, Alexander and Lunter, Gerton and Fiddy, Simon and Allan, Chris and Aricescu, A. Radu and Attar, Moustafa and Babbs, Christian and Becq, Jennifer and Beeson, David and Bento, Celeste and Bignell, Patricia and Blair, Edward and Buckle, Veronica J and Bull, Katherine and Cais, Ondrej and Cario, Holger and Chapel, Helen and Copley, Richard R and Cornall, Richard and Craft, Jude and Dahan, Karin and Davenport, Emma E and Dendrou, Calliope and Devuyst, Olivier and Fenwick, Aimée L and Flint, Jonathan and Fugger, Lars and Gilbert, Rodney D and Goriely, Anne and Green, Angie and Greger, Ingo H and Grocock, Russell and Gruszczyk, Anja V and Hastings, Robert and Hatton, Edouard and Higgs, Doug and Hill, Adrian and Holmes, Chris and Howard, Malcolm and Hughes, Linda and Humburg, Peter and Johnson, David and Karpe, Fredrik and Kingsbury, Zoya and Kini, Usha and Knight, Julian C and Krohn, Jonathan and Lamble, Sarah and Langman, Craig and Lonie, Lorne and Luck, Joshua and McCarthy, Davis and McGowan, Simon J and McMullin, Mary Frances and Miller, Kerry A and Murray, Lisa and Németh, Andrea H and Nesbit, M. Andrew and Nutt, David and Ormondroyd, Elizabeth and Bang Oturai, Annette and Pagnamenta, Alistair and Patel, Smita Y and Percy, Melanie and Petousi, Nayia and Piazza, Paolo and Piret, Sian E and Polanco-Echeverry, Guadalupe and Popitsch, Niko and Powrie, Fiona and Pugh, Chris and Quek, Lynn and Robbins, Peter A and Robson, Kathryn and Russo, Alexandra and Sahgal, Natasha and Van Schouwenburg, Pauline A and Schuh, Anna and Silverman, Earl and Simmons, Alison and Sorensen, Per Soelberg and Sweeney, Elizabeth and Taylor, John and Thakker, Rajesh V and Tomlinson, Ian and Trebes, Amy and Twigg, Stephen R. F and Uhlig, Holm H and Vyas, Paresh and Vyse, Tim and Wall, Steven A and Watkins, Hugh and Whyte, Michael P and Witty, Lorna and ...
Nature Genetics, ISSN 1061-4036, 06/2015, Volume 47, Issue 7, pp. 717 - 726
Journal Article
Cancer Research, ISSN 0008-5472, 10/2003, Volume 63, Issue 19, pp. 6130 - 6134
Journal Article
Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 05/2004, Volume 5, Issue 5, pp. 343 - 354
Journal Article