Radiology, ISSN 0033-8419, 01/2016, Volume 278, Issue 1, pp. 305 - 306
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2016, Volume 66, Issue 1, pp. 212 - 227
Summary Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells representing the interface between blood cells on the one side and...
Gastroenterology and Hepatology | Cirrhosis | Angiogenesis | Liver sinusoidal endothelial cells | Capillarization | Endothelial dysfunction | Drug delivery system | Liver regeneration | Endothelium | PROGENITOR CELLS | RAT-LIVER | PARTIAL-HEPATECTOMY | NITRIC-OXIDE SYNTHASE | TRANSGENIC MOUSE | MOUSE-LIVER | HEPATOCELLULAR-CARCINOMA | GENE-EXPRESSION | GASTROENTEROLOGY & HEPATOLOGY | PORTAL-HYPERTENSION | CRE-RECOMBINASE | Liver Diseases - physiopathology | Liver Diseases - metabolism | Humans | Hepatocytes - physiology | Liver Diseases - pathology | Liver diseases | Analysis | Physiological aspects | Development and progression | Genetic engineering | Cells
Gastroenterology and Hepatology | Cirrhosis | Angiogenesis | Liver sinusoidal endothelial cells | Capillarization | Endothelial dysfunction | Drug delivery system | Liver regeneration | Endothelium | PROGENITOR CELLS | RAT-LIVER | PARTIAL-HEPATECTOMY | NITRIC-OXIDE SYNTHASE | TRANSGENIC MOUSE | MOUSE-LIVER | HEPATOCELLULAR-CARCINOMA | GENE-EXPRESSION | GASTROENTEROLOGY & HEPATOLOGY | PORTAL-HYPERTENSION | CRE-RECOMBINASE | Liver Diseases - physiopathology | Liver Diseases - metabolism | Humans | Hepatocytes - physiology | Liver Diseases - pathology | Liver diseases | Analysis | Physiological aspects | Development and progression | Genetic engineering | Cells
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2012, Volume 56, Issue 1, pp. S25 - S38
Summary Primary damage to hepatic vessels is rare. (i) Hepatic arterial disorders, related mostly to iatrogenic injury and occasionally to systemic diseases,...
Gastroenterology and Hepatology | Hepatic venous outflow | Angioplasty | Portal hypertension | Cavernoma | Ischemic cholangiopathy | Anticoagulation | Portal vein thrombosis | TIPS | Liver transplantation | Idiopathic portal hypertension | PORTAL-VEIN THROMBOSIS | BONE-MARROW-TRANSPLANTATION | ORTHOTOPIC LIVER-TRANSPLANTATION | BUDD-CHIARI-SYNDROME | TRANSCATHETER THROMBOLYTIC THERAPY | NODULAR REGENERATIVE HYPERPLASIA | INTRAHEPATIC PORTOSYSTEMIC SHUNT | MESENTERIC VENOUS THROMBOSIS | SEVERE VENOOCCLUSIVE DISEASE | STEM-CELL TRANSPLANTATION | GASTROENTEROLOGY & HEPATOLOGY | Bile Ducts - blood supply | Budd-Chiari Syndrome - diagnosis | Humans | Ischemia - therapy | Liver Diseases - therapy | Hepatic Veno-Occlusive Disease - diagnosis | Ischemia - diagnosis | Hepatic Veno-Occlusive Disease - therapy | Portal Vein | Budd-Chiari Syndrome - therapy | Hypertension, Portal - diagnosis | Hypertension, Portal - etiology | Hypertension, Portal - therapy | Liver Diseases - diagnosis | Thrombosis - therapy | Ischemia - etiology | Thrombosis - diagnosis
Gastroenterology and Hepatology | Hepatic venous outflow | Angioplasty | Portal hypertension | Cavernoma | Ischemic cholangiopathy | Anticoagulation | Portal vein thrombosis | TIPS | Liver transplantation | Idiopathic portal hypertension | PORTAL-VEIN THROMBOSIS | BONE-MARROW-TRANSPLANTATION | ORTHOTOPIC LIVER-TRANSPLANTATION | BUDD-CHIARI-SYNDROME | TRANSCATHETER THROMBOLYTIC THERAPY | NODULAR REGENERATIVE HYPERPLASIA | INTRAHEPATIC PORTOSYSTEMIC SHUNT | MESENTERIC VENOUS THROMBOSIS | SEVERE VENOOCCLUSIVE DISEASE | STEM-CELL TRANSPLANTATION | GASTROENTEROLOGY & HEPATOLOGY | Bile Ducts - blood supply | Budd-Chiari Syndrome - diagnosis | Humans | Ischemia - therapy | Liver Diseases - therapy | Hepatic Veno-Occlusive Disease - diagnosis | Ischemia - diagnosis | Hepatic Veno-Occlusive Disease - therapy | Portal Vein | Budd-Chiari Syndrome - therapy | Hypertension, Portal - diagnosis | Hypertension, Portal - etiology | Hypertension, Portal - therapy | Liver Diseases - diagnosis | Thrombosis - therapy | Ischemia - etiology | Thrombosis - diagnosis
Journal Article
Hepato-Gastro et Oncologie Digestive, ISSN 2115-3310, 10/2018, Volume 25, Issue 8, pp. 755 - 763
Journal Article
Journal of Hepatology, ISSN 0168-8278, 06/2019, Volume 70, Issue 6, pp. 1278 - 1291
Non-alcoholic fatty liver disease (NAFLD) and its complications are an expanding health problem associated with the metabolic syndrome. Liver sinusoidal...
Endothelial dysfunction | Angiogenesis | Capillarization | Endothelium | Steatosis | RAT-LIVER | ACTIVATED PROTEIN-KINASE | LOW-DENSITY-LIPOPROTEIN | ACETYL-COA CARBOXYLASE | NEGATIVE FEEDBACK LOOP | HEPATIC MICROCIRCULATION | V-PYRRO/NO | INSULIN-RESISTANCE | NITRIC-OXIDE | GROWTH-FACTOR | GASTROENTEROLOGY & HEPATOLOGY | Adipose tissue | Liver diseases | Homeostasis | Hepatocellular carcinoma | Inflammation | Endothelial cells | Cell activation | Fatty liver | Hepatocytes | Developmental stages | Hedgehog protein | Fibrosis | Metabolic disorders
Endothelial dysfunction | Angiogenesis | Capillarization | Endothelium | Steatosis | RAT-LIVER | ACTIVATED PROTEIN-KINASE | LOW-DENSITY-LIPOPROTEIN | ACETYL-COA CARBOXYLASE | NEGATIVE FEEDBACK LOOP | HEPATIC MICROCIRCULATION | V-PYRRO/NO | INSULIN-RESISTANCE | NITRIC-OXIDE | GROWTH-FACTOR | GASTROENTEROLOGY & HEPATOLOGY | Adipose tissue | Liver diseases | Homeostasis | Hepatocellular carcinoma | Inflammation | Endothelial cells | Cell activation | Fatty liver | Hepatocytes | Developmental stages | Hedgehog protein | Fibrosis | Metabolic disorders
Journal Article
Nature Reviews Cardiology, ISSN 1759-5002, 05/2017, Volume 14, Issue 5, pp. 259 - 272
Membrane vesicles released in the extracellular space are composed of a lipid bilayer enclosing soluble cytosolic material and nuclear components....
CARDIAC & CARDIOVASCULAR SYSTEMS | PLATELET-DERIVED MICROPARTICLES | HUMAN ATHEROSCLEROTIC PLAQUES | CIRCULATING ENDOTHELIAL MICROPARTICLES | ACUTE MYOCARDIAL-INFARCTION | LOW-DENSITY-LIPOPROTEIN | SMOOTH-MUSCLE-CELLS | SHED MEMBRANE MICROPARTICLES | HIGH CARDIOVASCULAR RISK | TYPE-2 DIABETES-MELLITUS | LIPID-LOWERING THERAPY | Second Messenger Systems - drug effects | Coronary Artery Disease - metabolism | Humans | Extracellular Vesicles - physiology | Cell Communication - physiology | Second Messenger Systems - physiology | Biomarkers - blood | Drug Discovery | Development and progression | Care and treatment | Genetic aspects | Cell organelles | Coronary heart disease | Health aspects
CARDIAC & CARDIOVASCULAR SYSTEMS | PLATELET-DERIVED MICROPARTICLES | HUMAN ATHEROSCLEROTIC PLAQUES | CIRCULATING ENDOTHELIAL MICROPARTICLES | ACUTE MYOCARDIAL-INFARCTION | LOW-DENSITY-LIPOPROTEIN | SMOOTH-MUSCLE-CELLS | SHED MEMBRANE MICROPARTICLES | HIGH CARDIOVASCULAR RISK | TYPE-2 DIABETES-MELLITUS | LIPID-LOWERING THERAPY | Second Messenger Systems - drug effects | Coronary Artery Disease - metabolism | Humans | Extracellular Vesicles - physiology | Cell Communication - physiology | Second Messenger Systems - physiology | Biomarkers - blood | Drug Discovery | Development and progression | Care and treatment | Genetic aspects | Cell organelles | Coronary heart disease | Health aspects
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2010, Volume 53, Issue 6, pp. 1123 - 1134
Autophagy, or cellular self-digestion, is a cellular pathway crucial for development, differentiation, survival, and homeostasis. Its implication in human...
Gastroenterology and Hepatology | Hepatitis | Starvation | Autophagic vacuole | Hepatocellular carcinoma | Autophagosome | LC3 | Survival | RAT HEPATOCYTES | ALPHA-ANTITRYPSIN DEFICIENCY | ENDOPLASMIC-RETICULUM STRESS | STARVATION-INDUCED AUTOPHAGY | HEPATOCELLULAR-CARCINOMA | HEPATITIS-C VIRUS | INSULIN-RESISTANCE | GASTROENTEROLOGY & HEPATOLOGY | MALLORY-DENK BODIES | INTRACELLULAR INCLUSIONS | MUTANT ALPHA-ANTITRYPSIN-Z | Liver - pathology | Fatty Liver - pathology | Humans | Liver Diseases - pathology | Male | Autophagy - physiology | Liver - physiopathology | Liver Diseases, Alcoholic - physiopathology | Liver Neoplasms - physiopathology | Female | Liver Neoplasms - pathology | alpha 1-Antitrypsin Deficiency - pathology | Liver Diseases, Alcoholic - pathology | Acute Lung Injury - physiopathology | Carcinoma, Hepatocellular - physiopathology | Reperfusion Injury - pathology | Fatty Liver - physiopathology | Acute Lung Injury - pathology | Hepatitis, Viral, Human - pathology | Hepatitis, Viral, Human - physiopathology | Animals | Models, Biological | Carcinoma, Hepatocellular - pathology | Reperfusion Injury - physiopathology | alpha 1-Antitrypsin Deficiency - physiopathology | Mice | Liver Diseases - physiopathology | Proteins | Liver cancer | Leukemia | Lymphomas | Hepatitis C | Hepatitis C virus | Health aspects | Protein kinases
Gastroenterology and Hepatology | Hepatitis | Starvation | Autophagic vacuole | Hepatocellular carcinoma | Autophagosome | LC3 | Survival | RAT HEPATOCYTES | ALPHA-ANTITRYPSIN DEFICIENCY | ENDOPLASMIC-RETICULUM STRESS | STARVATION-INDUCED AUTOPHAGY | HEPATOCELLULAR-CARCINOMA | HEPATITIS-C VIRUS | INSULIN-RESISTANCE | GASTROENTEROLOGY & HEPATOLOGY | MALLORY-DENK BODIES | INTRACELLULAR INCLUSIONS | MUTANT ALPHA-ANTITRYPSIN-Z | Liver - pathology | Fatty Liver - pathology | Humans | Liver Diseases - pathology | Male | Autophagy - physiology | Liver - physiopathology | Liver Diseases, Alcoholic - physiopathology | Liver Neoplasms - physiopathology | Female | Liver Neoplasms - pathology | alpha 1-Antitrypsin Deficiency - pathology | Liver Diseases, Alcoholic - pathology | Acute Lung Injury - physiopathology | Carcinoma, Hepatocellular - physiopathology | Reperfusion Injury - pathology | Fatty Liver - physiopathology | Acute Lung Injury - pathology | Hepatitis, Viral, Human - pathology | Hepatitis, Viral, Human - physiopathology | Animals | Models, Biological | Carcinoma, Hepatocellular - pathology | Reperfusion Injury - physiopathology | alpha 1-Antitrypsin Deficiency - physiopathology | Mice | Liver Diseases - physiopathology | Proteins | Liver cancer | Leukemia | Lymphomas | Hepatitis C | Hepatitis C virus | Health aspects | Protein kinases
Journal Article
Hepatology, ISSN 0270-9139, 09/2010, Volume 52, Issue 3, pp. 1017 - 1022
Beta‐blockers may have a negative impact on survival in patients with cirrhosis and refractory ascites. The aim of this study was to evaluate the effect of the...
MORTALITY | LIVER-TRANSPLANTATION | MANAGEMENT | HEMODYNAMIC-CHANGES | MELD | TENSE ASCITES | SERUM SODIUM | HEPATORENAL-SYNDROME | TOTAL PARACENTESIS | GASTROENTEROLOGY & HEPATOLOGY | PORTAL-HYPERTENSION | Ascites - mortality | Liver Cirrhosis - drug therapy | Ascites - etiology | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Propranolol - therapeutic use | Kaplan-Meier Estimate | Liver Cirrhosis - mortality | Male | Survival Rate | Treatment Outcome | Ascites - drug therapy | Contraindications | Female | Renal Insufficiency - complications | Aged | Retrospective Studies | Longitudinal Studies | Adrenergic beta-Antagonists - therapeutic use | Hyponatremia - complications
MORTALITY | LIVER-TRANSPLANTATION | MANAGEMENT | HEMODYNAMIC-CHANGES | MELD | TENSE ASCITES | SERUM SODIUM | HEPATORENAL-SYNDROME | TOTAL PARACENTESIS | GASTROENTEROLOGY & HEPATOLOGY | PORTAL-HYPERTENSION | Ascites - mortality | Liver Cirrhosis - drug therapy | Ascites - etiology | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Propranolol - therapeutic use | Kaplan-Meier Estimate | Liver Cirrhosis - mortality | Male | Survival Rate | Treatment Outcome | Ascites - drug therapy | Contraindications | Female | Renal Insufficiency - complications | Aged | Retrospective Studies | Longitudinal Studies | Adrenergic beta-Antagonists - therapeutic use | Hyponatremia - complications
Journal Article
Circulation Research, ISSN 0009-7330, 08/2011, Volume 109, Issue 5, pp. 593 - 606
Membrane-shed submicron microparticles (MPs) are released after cell activation or apoptosis. High levels of MPs circulate in the blood of patients with...
atherosclerosis | endothelial microparticles | progenitor cells | thrombosis | angiogenesis | microparticle | CARDIAC & CARDIOVASCULAR SYSTEMS | PLATELET P-SELECTIN | SHED MEMBRANE MICROPARTICLES | ACUTE CORONARY SYNDROMES | IN-VITRO | CIRCULATING ENDOTHELIAL MICROPARTICLES | HUMAN ATHEROSCLEROTIC PLAQUES | PROTEIN-C RECEPTOR | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | STAGE RENAL-DISEASE | ACTIVE TISSUE FACTOR | Thrombosis - metabolism | Thrombosis - physiopathology | Animals | Atherosclerosis - physiopathology | Humans | Endothelium, Vascular - physiopathology | Cell-Derived Microparticles - pathology | Endothelium, Vascular - pathology | Cell-Derived Microparticles - metabolism | Atherosclerosis - metabolism | Endothelium, Vascular - physiology
atherosclerosis | endothelial microparticles | progenitor cells | thrombosis | angiogenesis | microparticle | CARDIAC & CARDIOVASCULAR SYSTEMS | PLATELET P-SELECTIN | SHED MEMBRANE MICROPARTICLES | ACUTE CORONARY SYNDROMES | IN-VITRO | CIRCULATING ENDOTHELIAL MICROPARTICLES | HUMAN ATHEROSCLEROTIC PLAQUES | PROTEIN-C RECEPTOR | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | STAGE RENAL-DISEASE | ACTIVE TISSUE FACTOR | Thrombosis - metabolism | Thrombosis - physiopathology | Animals | Atherosclerosis - physiopathology | Humans | Endothelium, Vascular - physiopathology | Cell-Derived Microparticles - pathology | Endothelium, Vascular - pathology | Cell-Derived Microparticles - metabolism | Atherosclerosis - metabolism | Endothelium, Vascular - physiology
Journal Article
Hepatology, ISSN 0270-9139, 02/2015, Volume 61, Issue 2, pp. 660 - 667
In cirrhosis, portal vein thrombosis (PVT) could be a cause or a consequence of the progression of liver disease. We analyzed data from a prospective trial of...
HYPERCOAGULABILITY | SURVIVAL | DIAGNOSIS | LIVER-TRANSPLANTATION | RISK-FACTORS | GENE | MUTATION | VENOUS THROMBOSIS | OUTCOMES | GASTROENTEROLOGY & HEPATOLOGY | Prospective Studies | Liver Cirrhosis - complications | Humans | Middle Aged | Female | Male | Longitudinal Studies | Portal Vein | Venous Thrombosis - etiology
HYPERCOAGULABILITY | SURVIVAL | DIAGNOSIS | LIVER-TRANSPLANTATION | RISK-FACTORS | GENE | MUTATION | VENOUS THROMBOSIS | OUTCOMES | GASTROENTEROLOGY & HEPATOLOGY | Prospective Studies | Liver Cirrhosis - complications | Humans | Middle Aged | Female | Male | Longitudinal Studies | Portal Vein | Venous Thrombosis - etiology
Journal Article