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The FEBS journal, ISSN 1742-4658, 2017, Volume 285, Issue 3, pp. 432 - 443
Metabolic activity of malignant cells is very different from that of their nontransformed equivalents, which establishes metabolic reprogramming as an... 
cancer | lysophosphatidic acid | metabolic reprogramming | lipid metabolism | TARGET | DE-NOVO LIPOGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SYNTHESIS PATHWAY | STEAROYL-COA DESATURASE | INHIBITION | PROSTATE-CANCER | OVARIAN | FATTY-ACID SYNTHASE | EXPRESSION | Neoplasms - metabolism | Receptors, Lysophosphatidic Acid - metabolism | Lysophospholipids - metabolism | Drugs, Investigational - pharmacology | Humans | Drugs, Investigational - therapeutic use | Neoplasm Proteins - antagonists & inhibitors | Receptors, Lysophosphatidic Acid - genetics | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | Sterol Regulatory Element Binding Protein 1 - agonists | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Neoplasms - blood | Lipids - blood | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Receptors, Lysophosphatidic Acid - antagonists & inhibitors | Neoplasm Proteins - genetics | Sterol Regulatory Element Binding Protein 1 - metabolism | Lysophospholipids - antagonists & inhibitors | Phosphoric Diester Hydrolases - metabolism | Lipids - antagonists & inhibitors | Lysophospholipids - blood | Phosphoric Diester Hydrolases - genetics | Stearoyl-CoA Desaturase - antagonists & inhibitors | Fatty Acid Synthase, Type I - metabolism | Stearoyl-CoA Desaturase - genetics | Fatty Acid Synthase, Type I - antagonists & inhibitors | Neoplasms - drug therapy | Phosphoric Diester Hydrolases - chemistry | Animals | Neoplasm Proteins - agonists | Signal Transduction - drug effects | Sterol Regulatory Element Binding Protein 1 - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Models, Biological | Lipogenesis - drug effects | Lipid Metabolism - drug effects | Stearoyl-CoA Desaturase - metabolism | Neoplasms - pathology | Physiological aspects | Cancer | Protein binding | Lipids | Biosynthesis | Metabolism | Signal transduction | Signaling | Lysophosphatidic acid | Rewiring | Transformed cells | Sterol regulatory element-binding protein | Stadiums | Lipid metabolism | Aberration
Journal Article
Cell Death and Disease, ISSN 2041-4889, 2017, Volume 8, Issue 5, pp. e2762 - e2762
...OPEN Targeted apoptosis in ovarian cancer cells through mitochondrial dysfunction in response to Sambucus nigra agglutinin Shreya Roy Chowdhury1, Upasana Ray1... 
ADHESION | TRANSLOCATION | PROTEIN | SIALYLATION | SURFACE | RESISTANCE | PROLIFERATION | GLYCOSYLATION | FISSION | CYTOCHROME-C RELEASE | CELL BIOLOGY | Cell Survival - drug effects | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Microtubule-Associated Proteins - metabolism | Cytochromes c - metabolism | Humans | Ovarian Neoplasms - pathology | Plant Lectins - pharmacology | Ribosome Inactivating Proteins - pharmacology | Mitochondria - metabolism | Membrane Potential, Mitochondrial - drug effects | Microscopy, Confocal | GTP Phosphohydrolases - metabolism | Mitochondrial Dynamics - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Mitochondrial Proteins - metabolism | Cytosol - metabolism | Female | Ovarian Neoplasms - metabolism | Proto-Oncogene Proteins c-akt - metabolism | S Phase Cell Cycle Checkpoints - drug effects | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Mitogen-Activated Protein Kinase 1 - metabolism | Phosphorylation | Reactive oxygen species | Cell survival | Ovarian carcinoma | Chemoresistance | Extracellular signal-regulated kinase | AKT protein | Sialic acids | Cytosol | Survival | Ovarian cancer | Cytochrome c | Mitochondria | Phytochemicals | Oxidative phosphorylation | Cell cycle | Dynamin | Apoptosis | Index Medicus
Journal Article
Seminars in Cancer Biology, ISSN 1044-579X, 09/2019
Quinacrine, also known as mepacrine, has originally been used as an antimalarial drug for close to a century, but was recently rediscovered as an anticancer... 
Drug repurposing | Breast cancer | Quinacrine | Endometrial cancer | Ovarian cancer
Journal Article
Journal Article
Molecular Oncology, ISSN 1574-7891, 05/2017, Volume 11, Issue 5, pp. 491 - 516
Extravasation and metastatic progression are two main reasons for the high mortality rate associated with cancer. The metastatic potential of cancer cells... 
ETS‐1 | HIF‐1α | lysophosphatidic acid | invasion | ovarian cancer | metabolic adaptations | HIF-1α | ETS-1 | ACTIVATION | HIF-1 alpha | PROTEIN | ONCOLOGY | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | PATHWAY | RECEPTORS | TRANSCRIPTION FACTOR | EXPRESSION | CARCINOMA | Adenocarcinoma - pathology | Proto-Oncogene Protein c-ets-1 - metabolism | Humans | Ovarian Neoplasms - pathology | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Gene Regulatory Networks - drug effects | Glycolysis - drug effects | Matrix Metalloproteinase Inhibitors - therapeutic use | Ovarian Neoplasms - genetics | Oxidative Phosphorylation - drug effects | Adenocarcinoma - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Lysophospholipids - pharmacology | Female | Adenocarcinoma - genetics | Ovarian Neoplasms - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Neoplasm Invasiveness | Mitochondria - metabolism | Matrix Metalloproteinase Inhibitors - pharmacology | Animals | Sequence Analysis, RNA | Cell Line, Tumor | Proto-Oncogene Protein c-ets-1 - antagonists & inhibitors | Proto-Oncogene Protein c-ets-1 - genetics | Mice | Mice, Inbred BALB C | Adaptations | Cell proliferation | Phosphorylation | Dehydrogenases | Epithelial cells | AKT protein | Metastasis | Kinases | Metastases | Ovarian cancer | Proteins | Bioenergetics | Metabolites | Extravasation | Tumorigenesis | Growth factors | Phenotypes | Invasiveness | Ribonucleic acid--RNA | Metabolism | Whooping cough | Acids | Oxidative phosphorylation | Lysophosphatidic acid | Glycolysis | Hypoxia
Journal Article
MICROORGANISMS, ISSN 2076-2607, 09/2019, Volume 7, Issue 9, p. 323
Dengue virus (DENV) is one of the lethal pathogens in the hot climatic regions of the world and has been extensively studied to decipher its mechanism of... 
PHOSPHATIDYLSERINE RECEPTORS | HUMAN DENDRITIC CELLS | SPLENIC MACROPHAGES | receptors | CD300A BINDS | MAST-CELLS | tropism | PRINCIPAL TARGET-CELLS | immune cells | MICROBIOLOGY | LANGERHANS CELLS | ANTIBODY-DEPENDENT ENHANCEMENT | entry | DENV | DC-SIGN | T-CELLS
Journal Article
Microorganisms (Basel), ISSN 2076-2607, 09/2019, Volume 7, Issue 9
Dengue virus (DENV) is one of the lethal pathogens in the hot climatic regions of the world and has been extensively studied to decipher its mechanism of... 
Journal Article