X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (14) 14
index medicus (13) 13
mutation (11) 11
animals (7) 7
breast cancer (7) 7
cell line, tumor (7) 7
female (7) 7
article (6) 6
oncology (6) 6
drug resistance, neoplasm - genetics (5) 5
erlotinib (5) 5
gefitinib (5) 5
protein kinase inhibitors - pharmacology (5) 5
acquired-resistance (4) 4
antineoplastic agents - therapeutic use (4) 4
biochemistry & molecular biology (4) 4
breast neoplasms - drug therapy (4) 4
cell biology (4) 4
epidermal growth factor (4) 4
growth-factor receptor (4) 4
mice (4) 4
models, molecular (4) 4
phosphorylation (4) 4
receptor, epidermal growth factor - genetics (4) 4
research (4) 4
respiratory tract diseases (4) 4
tyrosine kinase (4) 4
breast neoplasms - genetics (3) 3
breast-cancer (3) 3
cancer (3) 3
care and treatment (3) 3
cells (3) 3
erbb receptors - chemistry (3) 3
erbb receptors - genetics (3) 3
her2 (3) 3
inhibitor (3) 3
kinases (3) 3
lapatinib (3) 3
lung cancer (3) 3
lung neoplasms - drug therapy (3) 3
lung neoplasms - genetics (3) 3
male (3) 3
middle aged (3) 3
protein conformation (3) 3
protein kinase inhibitors - therapeutic use (3) 3
receptor, epidermal growth factor - antagonists & inhibitors (3) 3
receptor, erbb-2 - genetics (3) 3
sensitivity (3) 3
tyrosine kinase inhibitor (3) 3
xenograft model antitumor assays (3) 3
activation (2) 2
afatinib (2) 2
analysis (2) 2
antineoplastic agents - pharmacology (2) 2
azd9291 (2) 2
biochemistry (2) 2
biological sciences (2) 2
breast neoplasms - metabolism (2) 2
breast neoplasms - pathology (2) 2
carcinoma, non-small-cell lung - genetics (2) 2
cell lung-cancer (2) 2
cell proliferation (2) 2
cell transformation, neoplastic - genetics (2) 2
dimerization (2) 2
drug resistance, neoplasm (2) 2
erbb receptors - antagonists & inhibitors (2) 2
estrogen (2) 2
gene expression regulation, neoplastic (2) 2
gene mutations (2) 2
gene-mutations (2) 2
genetic aspects (2) 2
hek293 cells (2) 2
immunoblotting (2) 2
inhibition (2) 2
kinase domain (2) 2
ligands (2) 2
lung neoplasms - enzymology (2) 2
lung neoplasms - metabolism (2) 2
lung neoplasms - pathology (2) 2
medicine, research & experimental (2) 2
mice, nude (2) 2
molecular targeted therapy (2) 2
multidisciplinary sciences (2) 2
mutation, missense - genetics (2) 2
mutations (2) 2
neoplasms - genetics (2) 2
nih 3t3 cells (2) 2
phase-iii (2) 2
phenotype (2) 2
pnas plus (2) 2
proteins (2) 2
quinazolines - pharmacology (2) 2
quinazolines - therapeutic use (2) 2
receptor, epidermal growth factor - chemistry (2) 2
receptor, epidermal growth factor - metabolism (2) 2
receptor, erbb-2 - antagonists & inhibitors (2) 2
receptors, estrogen - genetics (2) 2
risk factors (2) 2
skin and connective tissue diseases (2) 2
stat3 transcription factor - metabolism (2) 2
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Clinical Investigation, ISSN 0021-9738, 12/2014, Volume 124, Issue 12, pp. 5490 - 5502
Estrogen receptor-positive (ER+) breast cancers adapt to hormone deprivation and become resistant to antiestrogen therapy. Here, we performed deep sequencing... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | NEOADJUVANT TREATMENT | AROMATASE INHIBITION | PHOSPHATIDYLINOSITOL 3-KINASE | TAMOXIFEN | THERAPEUTIC TARGET | IN-VIVO | ENDOCRINE THERAPY | SRC FAMILY KINASES | PHOSPHOINOSITIDE 3-KINASE | Gene Expression Regulation, Enzymologic - drug effects | Receptors, Estrogen - metabolism | Pyrimidines - agonists | Humans | Phosphatidylinositol 3-Kinases - metabolism | Mutation, Missense | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Thiazoles - agonists | Breast Neoplasms - metabolism | Phosphorylation - genetics | src-Family Kinases - metabolism | Morpholines - agonists | Female | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Aminopyridines - agonists | Gene Expression Regulation, Neoplastic - genetics | Dasatinib | Receptors, Estrogen - genetics | Morpholines - pharmacology | Pyrimidines - pharmacology | Breast Neoplasms - drug therapy | Estrogen Receptor Modulators - pharmacology | src Homology Domains | Drug Synergism | Phosphatidylinositol 3-Kinases - genetics | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Gene Expression Regulation, Enzymologic - genetics | Mice, Nude | Aminopyridines - pharmacology | Mice | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | src-Family Kinases - genetics | Amino Acid Substitution | Drug Resistance, Neoplasm - drug effects | Gene mutations | Estrogen | Physiological aspects | Breast cancer | Genetic aspects | Research | Health aspects | Risk factors | Medical research | Cell growth | Mutation | Kinases
Journal Article
Cancer Discovery, ISSN 2159-8274, 2014, Volume 4, Issue 9, pp. 1046 - 1061
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 11/2015, Volume 112, Issue 45, pp. E6205 - E6214
Journal Article
Cancer Cell, ISSN 1535-6108, 2009, Volume 15, Issue 3, pp. 165 - 166
The epithelial-specific cell adhesion molecule (EpCAM) modulates cell adhesion and proliferation. Its overexpression correlates with tumor cell proliferation,... 
NEUROGENESIS | ONCOLOGY | ANTIGEN EPCAM | CANCER | EP-CAM | CELL ADHESION MOLECULE | Neoplasms - metabolism | Animals | Cell Proliferation | Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Antigens, Neoplasm - metabolism | Signal Transduction - physiology | Cell Adhesion Molecules - metabolism | Epithelial Cell Adhesion Molecule | Proteolysis
Journal Article
Nature medicine, ISSN 1078-8956, 2014, Volume 20, Issue 9, pp. 1027 - 1034
Journal Article
Cancer Discovery, ISSN 2159-8274, 2013, Volume 3, Issue 2, pp. 138 - 140
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2014, Volume 124, Issue 12, pp. 5490 - 5490
Estrogen receptor-positive (ER super( +)) breast cancers adapt to hormone deprivation and become resistant to antiestrogen therapy. In this article, the... 
Journal Article
CANCER DISCOVERY, ISSN 2159-8274, 02/2013, Volume 3, Issue 2, pp. 138 - 140
Investigators report the identification of novel mutant-specific inhibition of EGF receptor (EGFR) T790M by bis-indole-based inhibitors of protein kinase C... 
CELL LUNG-CANCER | GEFITINIB | ONCOLOGY | SENSITIVITY | MUTATIONS | EGFR T790M | SELECTIVITY | RECEPTOR TYROSINE KINASE | ERLOTINIB | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Receptor, Epidermal Growth Factor - genetics | Protein Kinase Inhibitors - pharmacology | Animals | Mutation | Humans
Journal Article
Cancer Discovery, ISSN 2159-8274, 11/2015, Volume 5, Issue 11, pp. 1155 - 1163
Journal Article
Science Signaling, ISSN 1945-0877, 03/2016, Volume 9, Issue 421, pp. ra33 - ra33
Journal Article
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 12/2016, Volume 160, Issue 3, p. 457
Purpose Phosphatidylinositol 3-kinase (PI3K)/AKT pathway aberrations are common in human breast cancer. Furthermore, PIK3CA mutations are commonly associated... 
Epidermal growth factor | RNA | Analysis | Genomics | Estrogen | Genetic research | Breast cancer | Genetic aspects | Genomes | Gene expression | Cancer
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2013, Volume 110, Issue 38, pp. 15178 - 15178
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2013, Volume 110, Issue 38, p. E3595
  The initiation of epidermal growth factor receptor (EGFR) kinase activity proceeds via an asymmetric dimerization mechanism in which a "donor" tyrosine... 
Phosphorylation | Lung cancer | Mutation | Kinases | Crystal structure
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2015, Volume 112, Issue 45, pp. E6205 - E6214
Recurrent human epidermal growth factor receptor 2 ( ) missense mutations have been reported in human cancers. These mutations occur primarily in the absence... 
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8 Supplement, pp. 1106 - 1106
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.