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FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 11/2019, Volume 10
Immune cell therapies based on the integration of synthetic antigen receptors comprise a powerful strategy for the treatment of diverse diseases, most notably... 
genome editing | ACTIVATION | IMMUNE CELLS | synthetic antigen receptor | IMMUNOGLOBULIN | ANTIBODY | cellular immunotherapy | B cells | IMMUNOLOGY | SIGNAL-TRANSDUCTION | cellular engineering | CAR-T CELLS | CRISPR-Cas9 | ANTIGEN-RECEPTOR | GENE-TRANSFER | CYTOKINE RELEASE | LYMPHOCYTES | T cells
Journal Article
PLOS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, p. e35497
Immunodeficient mice reconstituted with human hematopoietic stem cells enable the in vivo study of human hematopoiesis. In particular, NOD-scid-IL2R... 
SEQUENCE-ANALYSIS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | V-REGIONS | IMMUNE-SYSTEM | CORD BLOOD | BIOLOGY | IMMUNOGLOBULIN REPERTOIRE | DIVERSITY | SELECTION | PLASMA-CELLS | GENE USAGE
Journal Article
Bioinformatics, ISSN 1367-4803, 12/2017, Volume 33, Issue 24, pp. 3938 - 3946
Motivation: The evolution of antibody repertoires represents a hallmark feature of adaptive B-cell immunity. Recent advancements in high-throughput sequencing... 
SOMATIC HYPERMUTATION | BIOCHEMICAL RESEARCH METHODS | IMMUNOGLOBULIN | VACCINATION | REGION | REARRANGEMENT | EVOLUTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MATHEMATICAL & COMPUTATIONAL BIOLOGY | DIVERSITY | GENERATION | INFECTION | MICE
Journal Article
PloS one, 2014, Volume 9, Issue 11, p. e111726
The humoral immune response plays a critical role in controlling infection, and the rapid adaptation to a broad range of pathogens depends on a highly diverse... 
HIV-1 | Immunoglobulin G - genetics | Immunoglobulin G - immunology | Humans | HIV Envelope Protein gp41 | Antibodies, Viral - immunology | Female | Immunoglobulin Variable Region - genetics | Male | High-Throughput Nucleotide Sequencing | Immunoglobulin Variable Region - immunology | Antibodies, Viral - genetics
Journal Article
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2018, Volume 9, p. 2149
Journal Article
2018 10th International Conference on Communication Systems and Networks, COMSNETS 2018, 03/2018, Volume 2018-, pp. 480 - 483
Conference Proceeding
Chimia, ISSN 0009-4293, 06/2016, Volume 70, Issue 6, pp. 439 - 442
Journal Article
PloS one, 2014, Volume 9, Issue 5, p. e96727
High-throughput sequencing (HTS) of antibody repertoire libraries has become a powerful tool in the field of systems immunology. However, numerous sources of... 
Sequence Analysis, RNA - methods | Animals | Gene Library | Computational Biology | Polymerase Chain Reaction | Antibodies - immunology | Antibodies - genetics | Female | Mice | High-Throughput Nucleotide Sequencing - methods
Journal Article
BMC Immunology, ISSN 1471-2172, 10/2014, Volume 15, Issue 1, pp. 40 - 40
Background: Next-generation sequencing (NGS) of antibody variable regions has emerged as a powerful tool in systems immunology by providing quantitative... 
DEEP | RNA | CLONING | RARE MUTATIONS | HUMORAL IMMUNITY | PHAGE DISPLAY | DIVERSITY | IMMUNOLOGY | HUMAN MONOCLONAL-ANTIBODIES | MEMORY B | PLASMA-CELLS | Physiological aspects | Plasma cells | Genetic research | Mice | Genetic aspects | Analysis | Immune response | Bone marrow | Plasma | Immunology | Vaccines | Cloning
Journal Article
International Journal of Pure and Applied Mathematics, ISSN 1311-8080, 2017, Volume 116, Issue 6, pp. 167 - 171
Journal Article