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Journal of Clinical Oncology, ISSN 0732-183X, 01/2015, Volume 33, Issue 3, pp. 251 - 257
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 2126 - 2126
Abstract Background: Proteasome inhibition with carfilzomib (CFZ) has shown to be effective therapy in relapsed refractory multiple myeloma (MM).1 Cardiac... 
Journal Article
Blood, ISSN 0006-4971, 02/2011, Volume 117, Issue 5, pp. 1453 - 1462
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2014, Volume 32, Issue 15_suppl, pp. 8586 - 8586
Journal Article
Mayo Clinic Proceedings, ISSN 0025-6196, 2013, Volume 88, Issue 4, pp. 360 - 376
Journal Article
Nature Medicine, ISSN 1078-8956, 12/2016, Volume 22, Issue 12, pp. 1411 - 1420
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. e19557 - e19557
Journal Article
Journal Article
Blood, ISSN 0006-4971, 08/2014, Volume 124, Issue 7, pp. 1047 - 1055
Journal Article
Blood, ISSN 0006-4971, 01/2018, Volume 131, Issue 2, pp. 182 - 190
Most patients with follicular lymphoma (FL) experience multiple relapses necessitating subsequent lines of therapy. Ibrutinib, a Bruton tyrosine kinase (BTK)... 
B-CELL RECEPTOR | BRUTONS TYROSINE KINASE | ACTIVATION | RESISTANCE | PCI-32765 | MECHANISMS | MUTATIONS | TARGETING BTK | INHIBITOR | HEMATOLOGY | SEQUENCING REVEALS | Index Medicus | Abridged Index Medicus | Clinical Trials and Observations
Journal Article
Investigational New Drugs, ISSN 0167-6997, 6/2014, Volume 32, Issue 3, pp. 489 - 499
Purpose Amplification or over-expression of the mitotic Aurora A kinase (AAK) has been reported in several heme-lymphatic malignancies. MLN8237 (alisertib) is... 
Novel antitumor agent | Medicine & Public Health | Aurora A kinase inhibitor | MLN8237 | Oncology | Cell cycle mechanisms of anticancer drug action | Pharmacology/Toxicology | Phase I-III Leukemia and lymphomas | APOPTOSIS | B ACTIVITY | INSTABILITY | RESPONSE CRITERIA | ALISERTIB MLN8237 | INCREASES | TARGETING AURORA | OVEREXPRESSION | ONCOLOGY | GROWTH | PHARMACOLOGY & PHARMACY | A KINASE | Humans | Middle Aged | Neoplasm Recurrence, Local - drug therapy | Male | Antineoplastic Agents - administration & dosage | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Protein Kinase Inhibitors - adverse effects | Aurora Kinase A - antagonists & inhibitors | Aurora Kinase A - metabolism | Multiple Myeloma - drug therapy | Antineoplastic Agents - adverse effects | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacokinetics | Aurora Kinase A - genetics | Lymphoma, Non-Hodgkin - drug therapy | Protein Kinase Inhibitors - pharmacokinetics | Azepines - adverse effects | Neoplasm Recurrence, Local - metabolism | Pyrimidines - administration & dosage | Lymphoma, Non-Hodgkin - genetics | Multiple Myeloma - metabolism | Protein Kinase Inhibitors - administration & dosage | Maximum Tolerated Dose | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Lymphoma, Non-Hodgkin - metabolism | Pyrimidines - adverse effects | Pyrimidines - pharmacokinetics | Neoplasm Recurrence, Local - genetics | Aged | Azepines - pharmacokinetics | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Azepines - administration & dosage | Multiple Myeloma - genetics | Antimitotic agents | Complications and side effects | Chronic lymphocytic leukemia | Care and treatment | Dosage and administration | Genetic aspects | Research | Antineoplastic agents | Pharmacokinetics | Inhibitor drugs | Statistical analysis | Research & development--R&D | Clinical trials | Patients | Cancer therapies | Pharmaceuticals | Index Medicus | Phase I Studies
Journal Article
Journal Article