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1. The burden of obesity on everyday life: A role for osteoarticular and respiratory diseases
by Marchesini, Giulio and Natale, S and Tiraferri, F and Tartaglia, A and Moscatiello, S and Marchesini Reggiani, L and Villanova, N and Forlani, G and Melchionda, N
Diabetes, Nutrition and Metabolism - Clinical and Experimental, ISSN 0394-3402, 10/2003, Volume 16, Issue 5-6, pp. 284 - 290
The burden of obesity on patients' everyday life is high; obese subjects perceive a poor Health-Related Quality of Life (HRQL) in both physical and mental... 
Obesity | Respiratory disease | Osteoarticular disease | Quality of life | SURGERY | osteoarticular disease | BEHAVIOR | SUBJECTIVE HEALTH | IMPAIRMENT | IMPACT | NUTRITION & DIETETICS | SUBJECTS SOS | respiratory disease | OVERWEIGHT | ENDOCRINOLOGY & METABOLISM | QUALITY-OF-LIFE | quality of life | WEIGHT | KNEE OSTEOARTHRITIS | obesity | Motor Activity - physiology | Joint Diseases - epidemiology | Obesity - psychology | Humans | Middle Aged | Male | Pain | Employment | Social Behavior | Adult | Female | Surveys and Questionnaires | Severity of Illness Index | Sexual Behavior | Obesity - complications | Logistic Models | Obesity - physiopathology | Hobbies | Respiratory Tract Diseases - etiology | Health Surveys | Joint Diseases - etiology | Respiratory Tract Diseases - epidemiology | Adolescent | Sex Factors | Quality of Life | Italy | Aged | Health Status
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2. Full Text Which type of observation for patients with high-risk mild head injury and negative computed tomography?
by Fabbri, Andrea and Servadei, Franco and Marchesini, Giulio and Dente, Massimo and Iervese, Tiziana and Spada, Marco and Vandelli, Alberto
European Journal of Emergency Medicine, ISSN 0969-9546, 04/2004, Volume 11, Issue 2, pp. 65 - 69
OBJECTIVE:Current guidelines suggest hospital admission followed by home monitoring for high-risk patients with mild head injury and negative computed... 
Neuroimaging | Head computed tomography | Observation | Unfavourable outcome | Neurosurgery | High-risk mild head injury | DIAGNOSIS | EMERGENCY MEDICINE | high-risk mild head injury | observation | ADULTS | RULE | neurosurgery | head computed tomography | unfavourable outcome | neuroimaging | Prospective Studies | Humans | Middle Aged | Risk Factors | Craniocerebral Trauma - diagnosis | Male | Tomography, X-Ray Computed | Craniocerebral Trauma - diagnostic imaging | Home Care Services | Observation - methods | Aged, 80 and over | Monitoring, Physiologic - methods | Adult | Aged
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3. Full Text Plasma Ghrelin Concentrations, Food Intake, and Anorexia in Liver Failure
by Marchesini, Giulio and Bianchi, Giampaolo and Lucidi, Paola and Villanova, Nicola and Zoli, Marco and De Feo, Pierpaolo
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 05/2004, Volume 89, Issue 5, pp. 2136 - 2141
Ghrelin is related to feeding behavior and nutrition in several physiological and pathological conditions. We tested the hypothesis that the anorexia and the... 
CACHEXIA | HORMONE | CRITICAL ILLNESS | CIRCULATING GHRELIN | INSULIN-RESISTANCE | CIRRHOSIS | ENDOCRINOLOGY & METABOLISM | HUMANS | SERUM LEPTIN | PORTAL HYPERTENSIVE GASTROPATHY | REPRODUCIBILITY | Eating | Liver Failure - complications | Liver Failure - physiopathology | Liver Cirrhosis - complications | Humans | Middle Aged | Peptide Hormones - blood | Male | Liver Cirrhosis - blood | Liver Failure - blood | Osmolar Concentration | Ghrelin | Anorexia - etiology | Adult | Female | Aged | Liver Cirrhosis - physiopathology
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4. Full Text Non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH): treatment
by Bugianesi, Elisabetta and Marzocchi, Rebecca and Villanova, Nicola and Marchesini, Giulio
Best Practice & Research Clinical Gastroenterology, ISSN 1521-6918, 2004, Volume 18, Issue 6, pp. 1105 - 1116
Non-alcoholic fatty liver disease is now recognized as a cause of potentially progressive liver damage, posing patients at risk of advanced liver failure.... 
treatment | insulin-sensitizing agents | fatty liver | anti-oxidants | lifestyle | Anti-oxidants | Lifestyle | Fatty liver | Insulin-sensitizing agents | Treatment | FIBROSIS | VITAMIN-E TREATMENT | METFORMIN | WEIGHT-LOSS | ALANINE AMINOTRANSFERASE | OBESE CHILDREN | PILOT-STUDY | URSODEOXYCHOLIC ACID | INSULIN-RESISTANCE | HEPATIC IRON | GASTROENTEROLOGY & HEPATOLOGY
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5. Full Text Non-alcoholic steatohepatitis in patients cared in metabolic units
by Marchesini, Giulio and Bugianesi, Elisabetta and Forlani, Gabriele and Marzocchi, Rebecca and Zannoni, Chiara and Vanni, Ester and Manini, Rita and Rizzetto, Mario and Melchionda, Nazario
Diabetes Research and Clinical Practice, ISSN 0168-8227, 2004, Volume 63, Issue 2, pp. 143 - 151
The clinical significance of liver disease is frequently underestimated in patients with metabolic disorders. In patients followed up in a metabolic unit for... 
Obesity | Fatty liver | Metabolic syndrome X | Diabetes, non-insulin dependent | Hyperlipidemia | hyperlipidemia | HOMEOSTASIS MODEL ASSESSMENT | RISK-FACTORS | FATTY LIVER-DISEASE | fatty liver | PREVALENCE | NATURAL-HISTORY | CRYPTOGENIC CIRRHOSIS | BETA-CELL FUNCTION | diabetes, non-insulin dependent | GENERAL-POPULATION | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | metabolic syndrome X | obesity | Blood Pressure | Body Mass Index | Liver - pathology | Diabetes Complications | Fatty Liver - pathology | Obesity - complications | Humans | Middle Aged | Coronary Disease - epidemiology | Male | Metabolic Syndrome - complications | Biopsy | Coronary Disease - complications | Triglycerides - blood | Cholesterol, HDL - blood | Adult | Female | Fatty Liver - epidemiology | Hyperlipidemias - complications
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6. Full Text Update on nutritional supplementation with branched-chain amino acids
by Bianchi, Giampaolo and Marzocchi, Rebecca and Agostini, Federica and Marchesini, Giulio
Current Opinion in Clinical Nutrition and Metabolic Care, ISSN 1363-1950, 01/2005, Volume 8, Issue 1, pp. 83 - 87
PURPOSE OF REVIEWBranched-chain amino acids (BCAAs) have a peculiar role in whole-body nitrogen metabolism. BCAAs are not only a substrate for protein... 
Neurotransmitter | Amino acids | Nitrogen balance | Protein catabolism | BED-REST | amino acids | HEPATOCYTE GROWTH-FACTOR | nitrogen balance | RANDOMIZED-TRIAL | PROTEIN-SYNTHESIS | NUTRITION & DIETETICS | DIETARY-PROTEIN | ENDOCRINOLOGY & METABOLISM | DOUBLE-BLIND | WHOLE-BODY | TARDIVE-DYSKINESIA | neurotransmitter | protein catabolism | HEPATIC-ENCEPHALOPATHY | SPINOCEREBELLAR DEGENERATION | Brain - metabolism | Amino Acids, Branched-Chain - administration & dosage | Amino Acids, Branched-Chain - therapeutic use | Humans | Neurotransmitter Agents - metabolism | Obesity - therapy | Liver Diseases - therapy | Muscle, Skeletal - metabolism | Dietary Supplements | Gluconeogenesis
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7. Full Text Clinical performance of NICE recommendations versus NCWFNS proposal in patients with mild head injury
by Fabbri, Andrea and Servadei, Franco and Marchesini, Giulio and Dente, Massimo and Iervese, Tiziana and Spada, Marco and Vandelli, Alberto
Journal of Neurotrauma, ISSN 0897-7151, 12/2005, Volume 22, Issue 12, pp. 1419 - 1427
Recommendations on treatment of patients with head injury were recently proposed by the National Institute for Clinical Excellence (NICE). We tested the... 
Head computed tomography | Clinical accuracy | Predictor variables | Outcomes | Mild head injury | DIAGNOSIS | mild head injury | MANAGEMENT | GLASGOW OUTCOME SCALE | ADULTS | NEUROSCIENCES | head computed tomography | COMPUTED-TOMOGRAPHY | CLINICAL NEUROLOGY | CHILDREN | EMERGENCY-DEPARTMENT | outcomes | predictor variables | INTRACRANIAL HEMATOMA | clinical accuracy | CRITICAL CARE MEDICINE | Prognosis | Outcome Assessment (Health Care) | Humans | Middle Aged | Craniocerebral Trauma - diagnosis | Tomography, X-Ray Computed | Trauma Severity Indices | Sensitivity and Specificity | Adolescent | Emergency Medical Services - standards | Adult | Aged | Child | Clinical trials | Head injuries | Medical imaging | Regression analysis | Medical treatment
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8. Full Text Diabetes prevention strategy in offspring of type 2 diabetic patients with a direct involvement of the diseased parents
by Bonomo, Katia and Fiora, Elisa and Caccavale, Ausilia and Traversa, Monica and Chirio, Massimo and Marchesini, Giulio and Trovati, Mariella
Nutrition, Metabolism and Cardiovascular Diseases, ISSN 0939-4753, 2005, Volume 15, Issue 3, pp. 237 - 238
CARDIAC & CARDIOVASCULAR SYSTEMS | NUTRITION & DIETETICS | ENDOCRINOLOGY & METABOLISM | Glucose Tolerance Test | Life Style | Risk Assessment | Diabetes Mellitus, Type 2 - genetics | Humans | Risk Factors | Diabetes Mellitus, Type 2 - prevention & control | Parents | Adult | Female | Male | Cause of Death
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9. Full Text Nonalcoholic fatty liver disease and the metabolic syndrome
by Marchesini, Giulio and Marzocchi, Rebecca and Agostini, Federica and Bugianesi, Elisabetta
Current Opinion in Lipidology, ISSN 0957-9672, 2005, Volume 16, Issue 4, pp. 421 - 427
Purpose of review Clinical, epidemiological and biochemical data strongly support the concept that nonalcoholic fatty liver disease is the hepatic... 
Hypertension | Treatment | Diabetes | Steatohepatitis | Dyslipidemia | steatohepatitis | treatment | CONTROLLED-TRIAL | METFORMIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | WEIGHT-LOSS | PREVALENCE | PATHOGENESIS | ADIPONECTIN | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | PERIPHERAL VASCULAR DISEASE | dyslipidemia | diabetes | hypertension | HEPATIC STEATOSIS | PENTOXIFYLLINE | Animals | Humans | Fatty Liver - drug therapy | Metabolic Syndrome - complications | Fatty Liver - etiology
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10. Full Text Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease
by Villanova, Nicola and Moscatiello, Simona and Ramilli, Stefano and Bugianesi, Elisabetta and Magalotti, Donatella and Vanni, Ester and Zoli, Marco and Marchesini, Giulio
Hepatology, ISSN 0270-9139, 08/2005, Volume 42, Issue 2, pp. 473 - 480
Nonalcoholic fatty liver disease (NAFLD) is consistently associated with features of the metabolic syndrome, a condition carrying a high risk of cardiovascular... 
UNITED-STATES | MORTALITY | METABOLIC SYNDROME | BRACHIAL-ARTERY | CAROTID ATHEROSCLEROSIS | FLOW-MEDIATED VASODILATION | CORONARY | INSULIN-RESISTANCE | PREVALENCE | GASTROENTEROLOGY & HEPATOLOGY | HEPATIC STEATOSIS | Cardiovascular Diseases - etiology | Fatty Liver - physiopathology | Humans | Middle Aged | Risk Factors | Endothelium, Vascular - physiopathology | Fatty Liver - complications | Male | Vasodilation | Adult | Brachial Artery - physiopathology | Female | Aged
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11. Full Text Insulin resistance: A metabolic pathway to chronic liver disease
by Bugianesi, Elisabetta and McCullough, Arthur J and Marchesini, Giulio
Hepatology, ISSN 0270-9139, 11/2005, Volume 42, Issue 5, pp. 987 - 1000
Insulin resistance (IR) is the pathophysiological hallmark of nonalcoholic fatty liver disease (NAFLD), one of the most common causes of chronic liver disease... 
PLASMA ADIPONECTIN CONCENTRATIONS | SKELETAL-MUSCLE TRIGLYCERIDE | NONALCOHOLIC FATTY LIVER | TUMOR-NECROSIS-FACTOR | HOMEOSTASIS MODEL ASSESSMENT | GLUCOSE-TOLERANCE TEST | ADIPOCYTE DIFFERENTIATION | TNF-ALPHA | GASTROENTEROLOGY & HEPATOLOGY | TYPE-2 DIABETES-MELLITUS | HEPATIC STEATOSIS | Insulin Resistance - physiology | Chronic Disease | Humans | Liver Diseases - etiology | Fatty Liver - etiology
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12. Full Text Weight Loss Expectations in Obese Patients and Treatment Attrition: An Observational Multicenter Study
by Grave, Riccardo and Calugi, Simona and Molinari, Enrico and Petroni, Maria Letizia and Bondi, Mario and Compare, Angelo and Marchesini, Giulio and QUOVADIS Study Grp and QUOVADIS Study Group
Obesity, ISSN 1930-7381, 11/2005, Volume 13, Issue 11, pp. 1961 - 1969
Objective: To investigate the influence of weight loss expectations (expected 1‐year BMI loss, dream and maximum acceptable BMI) on attrition in obese patients... 
psychiatric distress | attrition | body image | dream BMI | binge eating | Binge eating | Body image | Attrition | Dream BMI | Psychiatric distress | LONG-TERM | SUCCESS | SEEKING TREATMENT | DROP-OUT | MAINTENANCE | NUTRITION & DIETETICS | PATTERN | PREDICTORS | OVERWEIGHT | LOSS GOALS | OUTCOMES | Body Mass Index | Prospective Studies | Age Factors | Obesity - psychology | Humans | Middle Aged | Body Image | Male | Forecasting | Bulimia | Regression Analysis | Motivation | Time Factors | Weight Loss | Obesity - therapy | Adult | Female | Italy | Goals | Treatment Refusal - psychology
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13. Full Text Disease management of the metabolic syndrome in a community: Study design and process analysis on baseline data
by Melchionda, Nazario and Forlani, Gabrielle and La Rovere, Lucia and Argnani, Paola and Trevisani, Fausto and Zocchi, Donato and Savorani, Giandomenico and Covezzoli, Anna and De Rosa, Marisa and Marchesini, Giulio
Metabolic Syndrome and Related Disorders, ISSN 1540-4196, 03/2006, Volume 4, Issue 1, pp. 7 - 16
A comprehensive lifestyle approach is suggested as first-line treatment for the individual features of the metabolic syndrome, but the results in community... 
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14. Full Text Diabetes and liver disease: An ominous association
by Moscatiello, Simona and Manini, Rita and Marchesini, Giulio
Nutrition, Metabolism and Cardiovascular Diseases, ISSN 0939-4753, 2006, Volume 17, Issue 1, pp. 63 - 70
Abstract Diabetes mellitus and advanced liver disease are associated with each other more frequently than expected by chance, and such an association carries a... 
Cardiovascular | Cirrhosis | Non-alcoholic fatty liver | Viral hepatitis | Type 2 diabetes mellitus | Liver disease | Liver transplantation | viral hepatitis | CARDIAC & CARDIOVASCULAR SYSTEMS | liver disease | CHRONIC HEPATITIS-C | NONALCOHOLIC STEATOHEPATITIS | RANDOMIZED CONTROLLED-TRIAL | NONDIABETIC PATIENTS | NATURAL-HISTORY | HEPATOCELLULAR-CARCINOMA | NUTRITION & DIETETICS | non-alcoholic fatty liver | LIFE-STYLE | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | type 2 diabetes mellitus | FATTY LIVER | cirrhosis | liver transplantation | GLUCOSE-TOLERANCE | Liver Transplantation - adverse effects | Liver Cirrhosis - complications | Humans | Diabetes Mellitus - drug therapy | Hepatitis C, Chronic - complications | Diabetes Complications - etiology | Antioxidants - therapeutic use | Exercise | Diet | Liver Diseases - etiology | Liver Diseases - complications | Diabetes Mellitus - etiology | Cytoprotection | Fatty Liver - etiology | Diabetes
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15. Full Text Insulin glargine improves glycemic control and health-related quality of life in type 1 diabetes
by Manini, Rita and Forlani, Gabriele and Moscatiello, Simona and Zannoni, Chiara and Marzocchi, Rebecca and Marchesini, Giulio
Nutrition, Metabolism and Cardiovascular Diseases, ISSN 0939-4753, 2006, Volume 17, Issue 7, pp. 493 - 498
Abstract Background and aims Glargine improves glucose control and reduces the risk of nocturnal hypoglycemia compared with neutral protamine Hagedorn (NPH)... 
Cardiovascular | Hypoglycemia | Type 1 diabetes | Insulin | Glargine | Quality of life | type 1 diabetes | CARDIAC & CARDIOVASCULAR SYSTEMS | NUTRITION & DIETETICS | THERAPY | insulin | ANALOG | hypoglycemia | ENDOCRINOLOGY & METABOLISM | glargine | MELLITUS | quality of life | LISPRO | Glycated Hemoglobin A - analysis | Hypoglycemic Agents - therapeutic use | Hypoglycemia - epidemiology | Insulin, Long-Acting | Humans | Middle Aged | Cost of Illness | Male | Treatment Outcome | Diabetes Mellitus, Type 1 - drug therapy | Hypoglycemia - prevention & control | Insulin Glargine | Quality of Life | Adult | Female | Surveys and Questionnaires | Aged | Insulin - analogs & derivatives | Insulin - therapeutic use
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16. Full Text Monitoring intervention programmes for out-of-hospital cardiac arrest in a mixed urban and rural setting
by Fabbri, Andrea and Marchesini, Giulio and Spada, Marco and Iervese, Tiziana and Dente, Massimo and Galvani, Marcello and Vandelli, Alberto
Resuscitation, ISSN 0300-9572, 2006, Volume 71, Issue 2, pp. 180 - 187
Only a few data are available on the survival rate following out-of-hospital cardiac arrest in different Italian settings. We report an analysis of a 10-year... 
Witnessed cardiac arrest | Outcome predictors | Survival | Resuscitation | STATEMENT | PROFESSIONALS | survival | GUIDELINES | PREDICTING SURVIVAL | AUTOMATED EXTERNAL DEFIBRILLATORS | outcome predictors | AMERICAN-HEART-ASSOCIATION | CARDIOPULMONARY-RESUSCITATION | CARE | witnessed cardiac arrest | PUBLIC-ACCESS DEFIBRILLATION | EMERGENCY MEDICINE | resuscitation | OUTCOMES | CRITICAL CARE MEDICINE | Age Factors | Outcome Assessment (Health Care) | Humans | Logistic Models | Male | Urban Population | Cardiopulmonary Resuscitation | Defibrillators | Heart Arrest - mortality | Time Factors | Rural Population | Sex Factors | Aged, 80 and over | Female | Italy - epidemiology | Aged | Emergency Medical Services | Cohort Studies | Heart Arrest - therapy | Analysis | Emergency medical services | Cardiac arrest
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