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Molecules, ISSN 1420-3049, 2018, Volume 23, Issue 5, p. 1232
Three new transition metal complexes, Cu(II) 1, Co(II) 2, and Zn(II) 3 with ligand bimnap derived from 1-methyl-2-aminobenzimidazole and 2-hydroxynapthaldehyde... 
Toxicity profile | Cytotoxicity | DNA binding/cleavage | Metal complexes | Cell migration/adhesion | Apoptosis | metal complexes | DNA-BINDING | toxicity profile | COPPER(II) | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | adhesion | CHEMISTRY, MULTIDISCIPLINARY | DNA binding | DAMAGE | ZINC(II) COMPLEXES | AGENT | cleavage | IN-VITRO | cell migration | LIGAND | cytotoxicity | Apoptosis - drug effects | Free Radical Scavengers - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Crystallography, X-Ray | Male | Structure-Activity Relationship | Zinc - chemistry | Copper - chemistry | Coordination Complexes - pharmacology | Female | Antineoplastic Agents - pharmacology | Molecular Structure | Cell Survival - drug effects | Benzimidazoles - chemical synthesis | Cell Adhesion - drug effects | Cell Movement - drug effects | DNA - chemistry | Animals | Cell Line, Tumor | Coordination Complexes - chemical synthesis | Benzimidazoles - pharmacology | Ligands | Mice | Cobalt - chemistry | DNA Cleavage | Drug Screening Assays, Antitumor | Biotechnology | Toxicity | Crystallography | Necrosis | Cell adhesion & migration | Anticancer properties | X-ray crystallography | Benzimidazole | Cell adhesion | Nuclease | Copper | Coordination compounds | Deoxyribonucleic acid--DNA | Aminobenzimidazole | Tumor cell lines | Zinc | Side effects | Transition metal compounds | Cell death | In vivo methods and tests | Cell migration | Cancer | Calf thymus | cell migration/adhesion
Journal Article
Bioscience reports, ISSN 0144-8463, 05/2019, Volume 39, Issue 5
TEN1 protein is a key component of CST complex, implicated in maintaining the telomere homeostasis, and provides stability to the eukaryotic genome. Mutations... 
Proteins | Pathogenicity | Pathogens | Residues | Structural stability | Computer applications | Homeostasis | Single-nucleotide polymorphism | Software | Mutation | Structural analysis | Structure-function relationships
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, p. e17159
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 05/2018, Volume 19, Issue 5, p. 1492
Herein, we have synthesized and characterized a new benzimidazole-derived BnI ligand and its copper(II) complex, [Cu(BnI)(2)], 1, and zinc(II) complex,... 
Cytotoxicity | Nuclease activity | Toxicity | Metal complexes | Interaction with biomolecules | metal complexes | toxicity | ACID | HUMAN SERUM-ALBUMIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTITUMOR-ACTIVITY | INSIGHT | MOLECULAR DOCKING | CANCER | CHEMISTRY, MULTIDISCIPLINARY | nuclease activity | IN-VITRO | AGENTS | METAL | interaction with biomolecules | DERIVATIVES | cytotoxicity
Journal Article
Journal of biomolecular structure & dynamics, ISSN 0739-1102, 01/2020, pp. 1 - 9
Pyruvate dehydrogenase kinase 3 (PDK3) is a multifunctional enzyme that plays a central role in the cancer metabolic switch by blocking pyruvate catabolism in... 
Journal Article
Biomolecules, ISSN 2218-273X, 09/2019, Volume 9, Issue 9, p. 495
Studying drug–protein interactions has gained significant attention lately, and this is because the majority of drugs interact with proteins, thereby altering... 
human transferrin | rivastigmine tartrate | molecular docking | Alzheimer’s disease | spectroscopy | isotheral titration calorimetry | neurodegenerative disorders
Journal Article
FRONTIERS IN MICROBIOLOGY, ISSN 1664-302X, 02/2019, Volume 10, p. 8
Cancer and the associated secondary bacterial infections are leading cause of mortality, due to the paucity of effective drugs. Here, we have synthesized... 
quorum sensing | ASSAY | DNA-DAMAGE | MICROBIOLOGY | TOXICITY | NANOSTRUCTURES | IN-VITRO | molecular docking | GENOTOXICITY | silver nanopertioles (AgNPs) | G