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Molecules, ISSN 1420-3049, 2018, Volume 23, Issue 5, p. 1232
Three new transition metal complexes, Cu(II) 1, Co(II) 2, and Zn(II) 3 with ligand bimnap derived from 1-methyl-2-aminobenzimidazole and 2-hydroxynapthaldehyde... 
Toxicity profile | Cytotoxicity | DNA binding/cleavage | Metal complexes | Cell migration/adhesion | Apoptosis | metal complexes | DNA-BINDING | toxicity profile | COPPER(II) | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | adhesion | CHEMISTRY, MULTIDISCIPLINARY | DNA binding | DAMAGE | ZINC(II) COMPLEXES | AGENT | cleavage | IN-VITRO | cell migration | LIGAND | cytotoxicity | Apoptosis - drug effects | Free Radical Scavengers - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Crystallography, X-Ray | Male | Structure-Activity Relationship | Zinc - chemistry | Copper - chemistry | Coordination Complexes - pharmacology | Female | Antineoplastic Agents - pharmacology | Molecular Structure | Cell Survival - drug effects | Benzimidazoles - chemical synthesis | Cell Adhesion - drug effects | Cell Movement - drug effects | DNA - chemistry | Animals | Cell Line, Tumor | Coordination Complexes - chemical synthesis | Benzimidazoles - pharmacology | Ligands | Mice | Cobalt - chemistry | DNA Cleavage | Drug Screening Assays, Antitumor | Biotechnology | Toxicity | Crystallography | Necrosis | Cell adhesion & migration | Anticancer properties | X-ray crystallography | Benzimidazole | Cell adhesion | Nuclease | Copper | Coordination compounds | Deoxyribonucleic acid--DNA | Aminobenzimidazole | Tumor cell lines | Zinc | Side effects | Transition metal compounds | Cell death | In vivo methods and tests | Cell migration | Cancer | Calf thymus | cell migration/adhesion
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e93913
DNA is one of the major intracellular targets for a wide range of anticancer and antibiotic drugs. Elucidating the binding between small molecules and DNA... 
MIXED-LIGAND COMPLEXES | CIRCULAR-DICHROISM | GROOVE BINDING | RUTHENIUM(II) | MULTIDISCIPLINARY SCIENCES | TARGETS | HOECHST-33258 | FLUORESCENCE-SPECTRA | INTERCALATION | METAL-COMPLEXES | NUCLEIC-ACIDS | Iodides - pharmacology | Viscosity | Reactive Oxygen Species - metabolism | Thioinosine - pharmacology | Models, Molecular | Spectrometry, Fluorescence | DNA, Circular - drug effects | Static Electricity | Comet Assay | DNA - radiation effects | Spectrophotometry, Ultraviolet | Animals | Osmolar Concentration | Cattle | Light | Plasmids - drug effects | Superoxides - metabolism | Antimetabolites, Antineoplastic - pharmacology | Molecular Docking Simulation | DNA Damage | Nucleic Acid Conformation | Circular Dichroism | DNA - drug effects | DNA replication | DNA damage | Analysis | Physiological aspects | Genetic aspects | Health aspects | Mercaptopurine | Drugs | Fluorescence spectroscopy | Transcription | Toxicity | Nicking | Fluorescence | Biochemistry | Biopolymers | Experiments | Comet assay | Molecular docking | Life sciences | Deoxyribonucleic acid--DNA | Binding | Spectroscopy | Damage assessment | Bioassay | Bioassays | Metabolism | Electrostatic properties | Gene expression | DNA biosynthesis | Studies | Damage detection | Antibiotics | Spectrophotometry | Cancer | Calf thymus | Conformation | Deoxyribonucleic acid | DNA
Journal Article
Bioscience reports, ISSN 0144-8463, 05/2019, Volume 39, Issue 5
TEN1 protein is a key component of CST complex, implicated in maintaining the telomere homeostasis, and provides stability to the eukaryotic genome. Mutations... 
Proteins | Pathogenicity | Pathogens | Residues | Structural stability | Computer applications | Homeostasis | Single-nucleotide polymorphism | Software | Mutation | Structural analysis | Structure-function relationships
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, p. e17159
Journal Article
Journal Article
Molecular BioSystems, ISSN 1742-206X, 02/2015, Volume 11, Issue 2, pp. 522 - 531
Understanding the interaction of small molecules with DNA has become an active research area at the interface between chemistry, molecular biology and... 
ACRIDINE-ORANGE | BASES | RECOGNITION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITORY-ACTIVITY | COMPLEXES | BINDING-MODE | COUMARIN | ETHIDIUM-BROMIDE | NUCLEIC-ACIDS
Journal Article
Molecular bioSystems, ISSN 1742-206X, 02/2015, Volume 11, Issue 2, pp. 522 - 531
Understanding the interaction of small molecules with DNA has become an active research area at the interface between chemistry, molecular biology and... 
Viscosity | Nucleic Acid Denaturation | Temperature | Models, Molecular | Spectrometry, Fluorescence | Umbelliferones - chemistry | DNA - metabolism | Spectrophotometry, Ultraviolet | Umbelliferones - metabolism | Animals | Osmolar Concentration | Cattle | Molecular Docking Simulation | Kinetics | Nucleic Acid Conformation | Circular Dichroism
Journal Article
New Journal of Chemistry, ISSN 1144-0546, 01/2017, Volume 41, Issue 24, pp. 14924 - 14935
Sulindac is one of the most effective non-steroidal anti-inflammatory drugs (NSAIDs) and belongs to the arylalkanoic acid class. DNA is the major target for a... 
Binding | Enthalpy | Fluorescence | Modelling | Pharmacology | Nonsteroidal anti-inflammatory drugs | Gene expression | Chemical compounds | Deoxyribonucleic acid--DNA | Molecular docking
Journal Article