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Journal of neuroinflammation, ISSN 1742-2094, 2012, Volume 9, Issue 1, pp. 133 - 133
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 13, pp. E2997 - E3006
Inherited retinal degeneration (RD) is a devastating and currently untreatable neurodegenerative condition that leads to loss of photoreceptor cells and... 
CNG channel | Calpain | PKG | Apoptosis | In vivo imaging | in vivo imaging | ROD | MULTIDISCIPLINARY SCIENCES | GLUTATHIONE PEGYLATED LIPOSOMES | apoptosis | DEPENDENT PROTEIN-KINASE | PHOTORECEPTOR CELL-DEATH | calpain | MUTANT MICE | CYCLIC-GMP | CONE PHOTORECEPTORS | MOUSE RETINA | RETINITIS-PIGMENTOSA | Retina - drug effects | Cyclic GMP - pharmacology | Retina - metabolism | Retinal Degeneration - drug therapy | Blood-Retinal Barrier - drug effects | Cyclic GMP-Dependent Protein Kinases - metabolism | Retinal Degeneration - metabolism | Cyclic GMP - administration & dosage | Drug Delivery Systems | Blood-Retinal Barrier - metabolism | Animals | Cyclic GMP - analogs & derivatives | Signal Transduction - drug effects | Photoreceptor Cells - metabolism | Mice | Liposomes | Disease Models, Animal | Prevention | Drugs | Drug delivery systems | Usage | Retinal degeneration | Cyclic guanylic acid | Health aspects | Methods | Vehicles | Medical treatment | Guanosine | Medical services | Retina | Pharmacology | Drug delivery | Analogs | Heterogeneity | Cell activation | Cell death | Neurodegeneration | Cyclic GMP | Blindness | Eye diseases | Degeneration | Index Medicus | Biological Sciences | Physical Sciences | PNAS Plus | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Oftalmologi | Ophthalmology | Klinisk medicin
Journal Article
Glia, ISSN 0894-1491, 2014, Volume 62, Issue 7, pp. 1125 - 1141
To ensure efficient energy supply to the high demanding brain, nutrients are transported into brain cells via specific glucose (GLUT) and monocarboxylate... 
neurodegeneration | nutrient transporters | reactive astrocytes | proliferator‐activated receptor gamma co‐activator 1‐alpha | Nutrient transporters | Neurodegeneration | Proliferator-activated receptor gamma co-activator 1-alpha | Reactive astrocytes | MOUSE-BRAIN | ACTIVATED RECEPTOR-GAMMA | NEUROSCIENCES | MCT2 | SKELETAL-MUSCLE | proliferator-activated receptor gamma co-activator 1-alpha | MITOCHONDRIAL CHANGES | LACTATE | NEURONS | ENERGY-METABOLISM | NF-KAPPA-B | EXPRESSION | Glutamate Plasma Membrane Transport Proteins - metabolism | Leukocytes - pathology | Microglia - metabolism | White Matter - metabolism | Humans | Middle Aged | Astrocytes - pathology | Male | Glucose Transporter Type 3 - metabolism | Brain - metabolism | Brain - blood supply | Monocarboxylic Acid Transporters - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Aged, 80 and over | Microglia - pathology | Adult | Female | White Matter - blood supply | Multiple Sclerosis - metabolism | Cell Line | Endothelial Cells - metabolism | Axons - metabolism | Multiple Sclerosis, Chronic Progressive - pathology | Multiple Sclerosis, Chronic Progressive - metabolism | White Matter - pathology | Transcription Factors - metabolism | Axons - pathology | Brain - pathology | Multiple Sclerosis - pathology | Aged | Endothelial Cells - pathology | Leukocytes - metabolism | Astrocytes - metabolism | Proteins | Glucose metabolism | Brain | Multiple sclerosis | Physiological aspects | Brain damage | Development and progression | Glucose | Dextrose | Index Medicus
Journal Article
Journal Article
Acta neuropathologica, ISSN 0001-6322, 2012, Volume 124, Issue 3, pp. 397 - 410
Alterations in sphingolipid metabolism are described to contribute to various neurological disorders. We here determined the expression of enzymes involved in... 
Pathology | Neurosciences | Multiple sclerosis | Medicine & Public Health | Astrocytes | Acid sphingomyelinase | Ceramide | Blood–brain barrier | Blood-brain barrier | INDUCED APOPTOSIS | NECROSIS-FACTOR-ALPHA | 1-PHOSPHATE RECEPTOR 1 | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | SPHINGOSINE 1-PHOSPHATE | IN-VITRO | FTY720 | ENDOTHELIAL-CELLS | UP-REGULATION | EXPRESSION | Humans | Middle Aged | Astrocytes - pathology | Blood-Brain Barrier - physiopathology | Male | Monocytes - metabolism | Multiple Sclerosis - physiopathology | Monocytes - pathology | Aged, 80 and over | Adult | Female | Immunosuppressive Agents - pharmacology | Multiple Sclerosis - metabolism | Propylene Glycols - pharmacology | Astrocytes - drug effects | Ceramides - metabolism | Sphingomyelins - metabolism | Endothelial Cells - metabolism | Cells, Cultured | Fingolimod Hydrochloride | Blood-Brain Barrier - drug effects | Monocytes - drug effects | Sphingosine - pharmacology | Blood-Brain Barrier - pathology | Cell Movement - drug effects | Sphingosine - analogs & derivatives | Multiple Sclerosis - pathology | Aged | Endothelial Cells - pathology | Astrocytes - metabolism | Endothelial Cells - drug effects | Enzymes | Biological products | RNA | Sphingosine | Physiological aspects | Lipids | Inflammation | Index Medicus | Brain | Leukocyte migration | Sphingolipids | Gene expression | Metabolism | Substantia alba | Sphingomyelin phosphodiesterase | Neurological diseases | Monocytes | sphingomyelin | Lipid metabolism | Tumor necrosis factor- alpha
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 2014, Volume 128, Issue 2, pp. 267 - 277
Journal Article
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 2010, Volume 113, Issue 2, pp. 447 - 453
Normal neuronal functioning is dependent on the blood-brain barrier. This barrier is confined to specialized brain endothelial cells lining the inner vessel... 
Endothelial cell | Multiple sclerosis | Blood-brain barrier | Monocyte | NMDA receptor | Tissue-type plasminogen activator | blood-brain barrier | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TISSUE-PLASMINOGEN ACTIVATOR | endothelial cell | multiple sclerosis | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | NEUROTOXICITY | NEUROSCIENCES | NEUROLOGICAL DEFICITS | MULTIPLE-SCLEROSIS | GLUTAMATE | INFLAMMATION | monocyte | CENTRAL-NERVOUS-SYSTEM | tissue-type plasminogen activator | Leukocyte Common Antigens - metabolism | Humans | Encephalomyelitis, Autoimmune, Experimental - etiology | Encephalomyelitis, Autoimmune, Experimental - immunology | Phosphoproteins - metabolism | Cell Movement - physiology | Blood-Brain Barrier - physiology | Female | Chemokine CCL2 - metabolism | Membrane Proteins - metabolism | Monocytes - physiology | Endothelial Cells - physiology | Disease Models, Animal | Brain - cytology | Encephalomyelitis, Autoimmune, Experimental - pathology | Immunoprecipitation - methods | Cells, Cultured | Myelin-Oligodendrocyte Glycoprotein | Excitatory Amino Acid Antagonists - pharmacology | Enzyme Activation - drug effects | Blood-Brain Barrier - drug effects | Receptors, N-Methyl-D-Aspartate - physiology | Monocytes - drug effects | Cell Movement - drug effects | Myelin-Associated Glycoprotein - immunology | Animals | Tissue Plasminogen Activator - pharmacology | Zonula Occludens-1 Protein | Signal Transduction - drug effects | Myelin Proteins | Mice | Dizocilpine Maleate - pharmacology | Endothelial Cells - drug effects | Methyl aspartate | Cell research | Neurons | Proteases | Thrombolytic drugs | Endothelium | Brain | Autoimmune diseases | Cells | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 12/2012, Volume 164, Issue 3, pp. 364 - 369
Journal Article
Journal Article