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Cancer research, ISSN 0008-5472, 09/2019, p. canres.1165.2019
Systemic dissemination of tumor cells often begins long before the development of overt metastases, revealing the inefficient nature of the metastatic process.... 
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2010, Volume 12, Issue 3, pp. 247 - 256
MicroRNAs (miRNAs) are increasingly implicated in regulating the malignant progression of cancer. Here we show that miR-9, which is upregulated in breast... 
ADHESION | STEM-CELLS | INVASION | N-MYC | C-MYC | TUMOR ANGIOGENESIS | HUMAN BREAST-CANCER | MESENCHYMAL TRANSITION | EXPRESSION | MAMMARY EPITHELIAL-CELLS | CELL BIOLOGY | Oncogene Proteins - genetics | RNA, Small Interfering - genetics | Protein Binding - genetics | Cell Proliferation | MicroRNAs - antagonists & inhibitors | Cadherins - metabolism | Gene Expression - genetics | Humans | 3' Untranslated Regions - genetics | Vascular Endothelial Growth Factor A - genetics | N-Myc Proto-Oncogene Protein | Cadherins - genetics | Oncogene Proteins - metabolism | Vascular Endothelial Growth Factor A - blood | Epithelial Cells - pathology | DNA - metabolism | Neuroblastoma - diagnosis | beta Catenin - metabolism | Down-Regulation - genetics | Cell Line, Tumor | Mice, Inbred NOD | Mice | Mice, Inbred BALB C | Neovascularization, Pathologic - metabolism | Neuroblastoma - metabolism | Proto-Oncogene Proteins c-myc - genetics | Histones - metabolism | MicroRNAs - physiology | Neoplasms - metabolism | Epithelial Cells - metabolism | Vimentin - metabolism | Lung Neoplasms - pathology | Breast Neoplasms - metabolism | Neovascularization, Pathologic - pathology | Neoplasms - blood | Transfection | Lung Neoplasms - secondary | Neoplasm Invasiveness - pathology | Female | Nuclear Proteins - genetics | Gene Expression Regulation, Neoplastic - physiology | Neuroblastoma - pathology | Cell Line | Neuroblastoma - genetics | Nuclear Proteins - metabolism | Gene Dosage | Mice, SCID | Proto-Oncogene Proteins c-myc - metabolism | beta Catenin - genetics | Neoplasm Metastasis - genetics | Animals | Breast Neoplasms - pathology | Neoplasm Metastasis - pathology | Signal Transduction - physiology | Transplantation, Heterologous - pathology | Neoplasm Invasiveness - genetics | Neoplasms - pathology | MicroRNA | Physiological aspects | Cadherins | Development and progression | Genetic aspects | Metastasis | Research | Oncogenes
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2011, Volume 108, Issue 19, pp. 7950 - 7955
Journal Article
Science, ISSN 0036-8075, 03/2016, Volume 351, Issue 6277, pp. 1042 - 1042
Journal Article
Cell, ISSN 0092-8674, 07/2013, Volume 154, Issue 1, p. 61
The recent discovery that normal and neoplastic epithelial cells re-enter the stem cell state raised the intriguing possibility that the aggressiveness of... 
Journal Article
Genes and Development, ISSN 0890-9369, 11/2009, Volume 23, Issue 22, pp. 2592 - 2597
It remains unclear whether a microRNA ( miRNA) affects a given phenotype via concomitant down-regulation of its entire repertoire of targets or instead by... 
miR-31 | Pleiotropy | Breast cancer | MicroRNA | Metastasis | Colonization | BREAST-CANCER CELLS | metastasis | colonization | GENETICS & HEREDITY | breast cancer | PROLIFERATION | DEVELOPMENTAL BIOLOGY | pleiotropy | FAMILY | CELL BIOLOGY | RNA | Analysis | Genetic aspects | Research | Genetic regulation
Journal Article
PLoS Biology, ISSN 1544-9173, 2014, Volume 12, Issue 9, p. e1001945
Malignant carcinomas that recur following therapy are typically de-differentiated and multidrug resistant (MDR). De-differentiated cancer cells acquire MDR by... 
EPITHELIAL-MESENCHYMAL TRANSITION | UNFOLDED PROTEIN RESPONSE | DIFFERENTIATION THERAPY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PANCREATIC-CANCER | BIOLOGY | NRF2 TRANSCRIPTION FACTOR | HEME OXYGENASE-1 GENE | ENDOPLASMIC-RETICULUM STRESS | DRUG-RESISTANCE | CANCER STEM-CELLS | ACUTE PROMYELOCYTIC LEUKEMIA | Phosphorylation | eIF-2 Kinase - metabolism | Humans | Gene Expression Regulation, Neoplastic | Neoplasm Recurrence, Local - drug therapy | Gene Expression Profiling | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | Neoplasm Recurrence, Local - pathology | Neoplasm Grading | Mammary Neoplasms, Experimental - pathology | Female | NF-E2-Related Factor 2 - genetics | Transcription, Genetic | Antineoplastic Agents - pharmacology | Carcinoma - pathology | Mammary Neoplasms, Experimental - drug therapy | eIF-2 Kinase - genetics | Carcinoma - drug therapy | Neoplasm Recurrence, Local - metabolism | Oxidation-Reduction | Signal Transduction | Mammary Glands, Animal - pathology | Mammary Glands, Animal - drug effects | Mice, SCID | Breast Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | Animals | Breast Neoplasms - genetics | Mammary Glands, Animal - metabolism | Breast Neoplasms - pathology | NF-E2-Related Factor 2 - metabolism | Cell Line, Tumor | Carcinoma - genetics | Mice, Inbred NOD | Neoplasm Recurrence, Local - genetics | Carcinoma - metabolism | Cell Dedifferentiation - genetics | Medical research | Enzymes | Transcription factors | Biomedical research | Breast cancer | Kinases | Drug resistance | Gene expression | Experiments | Cancer therapies | Antioxidants | Medical prognosis | Data collection | Tumors
Journal Article
Cancer Research, ISSN 0008-5472, 06/2010, Volume 70, Issue 12, pp. 5147 - 5154
miR-31 inhibits breast cancer metastasis via the pleiotropic suppression of a cohort of pro-metastatic target genes that include integrin α5, radixin, and... 
miR-31 | breast cancer | microRNA | invasion-metastasis cascade | metastatic colonization | metastasis
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2011, Volume 121, Issue 2, pp. 784 - 799
Journal Article