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Journal of Clinical Neuroscience, ISSN 0967-5868, 2013, Volume 21, Issue 3, pp. 488 - 492
Journal Article
The Journal of Pathology, ISSN 0022-3417, 06/2009, Volume 218, Issue 2, pp. 241 - 247
We deciphered constituent parts of a signal transduction cascade that is initiated by collagen II and results in the release of various pro‐inflammatory... 
kinase inhibitor | osteoarthritis | PHC | siRNA | collagen II | DDR2 | IL‐6 | Collagen II | Kinase inhibitor | Osteoarthritis | IL-6 | MATRIX | ACTIVATION | CYTOKINES | SYNOVIAL-FLUID | TYROSINE KINASES | PATHOLOGY | P38 MAP KINASE | ONCOLOGY | ARTICULAR-CARTILAGE | MATRIX-METALLOPROTEINASE-13 | EXPRESSION | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Immunoblotting | JNK Mitogen-Activated Protein Kinases - metabolism | NF-kappa B - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Discoidin Domain Receptors | Knee Joint | RNA Interference | p38 Mitogen-Activated Protein Kinases - metabolism | Chondrocytes - secretion | Chondrocytes - metabolism | Collagen Type II - pharmacology | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | RNA, Small Interfering - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Receptors, Mitogen - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Interleukin-6 - secretion | Analysis of Variance | Receptor Protein-Tyrosine Kinases - genetics | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Signal Transduction - physiology | Osteoarthritis, Knee - metabolism | Receptors, Mitogen - genetics | Transcription factors | Collagen (type II) | Extracellular signal-regulated kinase | Intracellular signalling | MAP kinase | Inflammation | 1-Phosphatidylinositol 3-kinase | Interleukin 6 | Gene silencing | Signal transduction | Side effects | c-Jun amino-terminal kinase | Chondrocytes | Lipid kinase | Cartilage diseases
Journal Article
FEBS Letters, ISSN 0014-5793, 11/2009, Volume 583, Issue 22, pp. 3611 - 3617
Here, we tested the matrilin-3-dependent induction of osteoarthritis-associated genes in primary human chondrocytes. Matrilin stimulation leads to the... 
Matrilin | Collagen II | Osteoarthritis | TNF | Interleukin | A disintegrin and MMP with thrombospondin motif | c-Jun NH2-terminal kinase | extracellular signal-regulated kinase | JNK | matrix-metalloproteinases | ADAMTS | primary human chondrocytes | MAPK | PHCs | LPS | mitogen-activated protein kinase | MMP | a disintegrin and MMP with thrombospondin motifs | lipopolysaccharide | ERK | SELECTIVE-INHIBITION | ADAPTER PROTEINS | MOLECULAR-STRUCTURE | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CARTILAGE | CELL BIOLOGY | BIOPHYSICS | TISSUE DISTRIBUTION | DEGRADATION | EXTRACELLULAR-MATRIX | Chondrocytes - cytology | Humans | Immunoblotting | Matrilin Proteins | Chondrocytes - drug effects | Procollagen N-Endopeptidase - metabolism | Cyclooxygenase 2 - genetics | Interleukin-8 - secretion | Chondrocytes - metabolism | Matrix Metalloproteinase 1 - genetics | Interleukin-1beta - secretion | ADAMTS5 Protein | Enzyme-Linked Immunosorbent Assay | Interleukin-6 - genetics | Extracellular Matrix Proteins - genetics | Matrix Metalloproteinase 13 - genetics | Tumor Necrosis Factor-alpha - secretion | Cells, Cultured | Extracellular Matrix Proteins - pharmacology | Recombinant Proteins - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Osteoarthritis - genetics | ADAMTS4 Protein | Gene Expression Regulation - drug effects | ADAM Proteins - metabolism | Nitric Oxide Synthase Type II - genetics | Matrix Metalloproteinase 3 - genetics | Collagenases | Universities and colleges | Mitogens | Protein kinases | Collagen
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 2636 - 2636
Abstract Abstract 2636 Purpose: To improve fertility advice in HL patients before treatment and counseling during survivorship, detailed information on the... 
Journal Article
Biochemia Medica, ISSN 1330-0962, 2012, Volume 22, Issue 3, pp. 373 - 379
Journal Article
10/2012, Volume 22, Issue 3
Introduction: Heavy chain diseases (HCD) are neoplastic proliferations of B cells which secrete truncated immunoglobulin heavy chains without associated light... 
arthritis, rheumatoid | electrophoresis, capillary | heavy chain disease | electrophoresis | immunoglobulin gamma-chains
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