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Philosophical Transactions of the Royal Society B: Biological Sciences, ISSN 0962-8436, 03/2014, Volume 369, Issue 1638, pp. 20130100 - 20130100
Journal Article
Philosophical Transactions: Biological Sciences, ISSN 0962-8436, 3/2014, Volume 369, Issue 1638, pp. 1 - 9
The change of a normal, healthy cell to a trasformed cell is the first step in the evolutionary arc of a cancer. While the role of oncogenes in this 'passage'... 
Protons | Cell growth | Cellular metabolism | Glycolysis | Hypoxia | Neoplastic cell transformation | Metastasis | Neoplasia | Cancer
Journal Article
Philosophical Transactions of the Royal Society B: Biological Sciences, ISSN 0962-8436, 03/2014, Volume 369, Issue 1638, p. 20130100
Journal Article
PLoS ONE, 11/2014, Volume 9, Issue 11
Background Umbilical cord matrix mesenchymal stem cells (UCM-MSCs) present a wide range of potential therapeutical applications. The extracellular... 
Journal Article
Journal Article
Journal of Bioenergetics and Biomembranes, ISSN 0145-479X, 6/2016, Volume 48, Issue 3, pp. 197 - 210
Journal Article
The FEBS Journal, ISSN 1742-464X, 06/2018, Volume 285, Issue 11, pp. 2104 - 2124
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers. Its aggressiveness is driven by an intense fibrotic desmoplastic reaction in which... 
pancreatic adenocarcinoma | VEFGR‐2 | cancer stem cells | vasculogenic mimicry | 3D organotypic cultures | desmoplastic reaction | VEFGR-2 | PANCREATIC DUCTAL ADENOCARCINOMA | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | 3D CULTURE | PHENOTYPE | DESMOPLASIA | STROMAL BIOLOGY | GROWTH | CANCER PROGRESSION | TUMOR MICROENVIRONMENT | Adenocarcinoma - pathology | Neoplastic Stem Cells - drug effects | Humans | Vascular Endothelial Growth Factor A - genetics | Carcinoma, Pancreatic Ductal - genetics | Neovascularization, Pathologic - pathology | Vascular Endothelial Growth Factor Receptor-2 - genetics | Extracellular Matrix - genetics | Neoplasm Metastasis | Tumor Microenvironment - genetics | Neoplasm Invasiveness - pathology | Neoplastic Stem Cells - pathology | Adenocarcinoma - genetics | Cell Culture Techniques | Gene Expression Regulation, Neoplastic - drug effects | Parenchymal Tissue - drug effects | Extracellular Matrix - drug effects | Parenchymal Tissue - pathology | Carcinoma, Pancreatic Ductal - pathology | Cell Plasticity - genetics | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Cell Proliferation - drug effects | Collagen Type I - pharmacology | Neoplasm Invasiveness - genetics | Vascular endothelial growth factor | Collagen | Pancreatic cancer | Stem cells | Adenocarcinoma | Phenotypes | Collagen (type I) | Composition | Invasiveness | Collagens | Stroma | Secretome | Mimicry | Metastases | Vascular endothelial growth factor receptors | Angiogenesis | Laminin | Fibrosis | Extracellular matrix | Infiltration | Pancreas | Cancer | Tumors
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1661-6596, 08/2019, Volume 20, Issue 15, p. 3694
Cancer cells have an unusual regulation of hydrogen ion dynamics that are driven by poor vascularity perfusion, regional hypoxia, and increased glycolysis. All... 
proton transport in cancer | MONOCARBOXYLATE TRANSPORTERS | NHE1 | pH and cancer | ACID | pH and Warburg metabolism | tumor metabolic microenvironment | PH DYNAMICS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-CELLS | CHEMISTRY, MULTIDISCIPLINARY | H+ exchanger | CARBONIC-ANHYDRASE IX | MCT1 | Na+ | INTRACELLULAR ALKALINIZATION | NA+/H+ EXCHANGER | EXPRESSION | Na+/H+ exchanger
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, p. e111533
Background: Umbilical cord matrix mesenchymal stem cells (UCM-MSCs) present a wide range of potential therapeutical applications. The extracellular... 
PHENOTYPIC CHARACTERIZATION | ACTIVATED PROTEIN-KINASE | THERAPY | MULTIDISCIPLINARY SCIENCES | PROLIFERATION | STROMAL CELLS | AMNIOTIC-FLUID | EXPRESSION | CA2+-SENSING RECEPTOR | EQUINE TENDON | BLOOD | Biomarkers - metabolism | Cell Line | Mesenchymal Stromal Cells - drug effects | Phenethylamines - pharmacology | Osteogenesis - drug effects | Umbilical Cord - cytology | Neurons - cytology | Receptors, Calcium-Sensing - metabolism | Receptors, Calcium-Sensing - agonists | Gene Expression Regulation - drug effects | Mesenchymal Stromal Cells - cytology | Animals | Biphenyl Compounds - pharmacology | Horses | Cell Proliferation - drug effects | Neurogenesis - drug effects | Neurons - drug effects | Phosphates | Stem cell research | RNA | Analysis | Stem cells | Physiological aspects | Research | Cell differentiation | Cell proliferation | Biotechnology | Alkaline phosphatase | Nestin | Transcription | Calcium | Mesenchyme | Gene regulation | Veterinary services | Stem cell transplantation | Clinical trials | Smooth muscle | Proteins | Biomedical materials | Cell growth | Allografts | Down-regulation | Bone marrow | Biocompatibility | Bioindicators | Cbfa-1 protein | Antigens | Incubation | Dose-response effects | Gene expression | College campuses | Calcium phosphates | Medicine | Studies | Cell lines | Biomarkers | Umbilical cord | Differentiation | Calcium (extracellular) | Binding sites | Calcium-sensing receptors
Journal Article
Journal Article
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 01/2010, Volume 21, Issue 1, pp. 73 - 86
We have demonstrated that Na+/H+ exchanger regulatory factor 1 (NHERF1) overexpression in CFBE41o- cells induces a significant redistribution of F508del cystic... 
Journal Article