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The New England Journal of Medicine, ISSN 0028-4793, 09/2014, Volume 371, Issue 11, pp. 1005 - 1015
About 25% of young adults with ALL have Ph-like genotypes, which are associated with poor outcomes with conventional treatment. In this gene-expression study,... 
MEDICINE, GENERAL & INTERNAL | MODELS | B-CELL PRECURSOR | INHIBITOR THERAPY | IMATINIB | PEDIATRIC ACUTE LEUKEMIAS | GENE FUSION | EXPRESSION | ETV6-NTRK3 FUSION TRANSCRIPTS | CRLF2 | DELETION | Oligonucleotide Array Sequence Analysis | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Humans | Child, Preschool | Infant | Male | Young Adult | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Heterografts | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Adult | Female | DNA, Neoplasm - analysis | Receptors, Cytokine - metabolism | Child | Philadelphia Chromosome | Receptors, Cytokine - genetics | Signal Transduction - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Protein Kinase Inhibitors - therapeutic use | Adolescent | Survival Analysis | Mice | Polymorphism, Single Nucleotide | Genome, Human | Protein-Tyrosine Kinases - antagonists & inhibitors | Development and progression | Care and treatment | Genetic aspects | Research | Lymphocytic leukemia | Tyrosine metabolism | Cell proliferation | Tyk2 protein | Leukemia | Genes | Clinical trials | Oncology | Genomes | Kinases | Cell activation | Janus kinase 2 | Xenografts | Teenagers | Children | Adolescents | Protein-tyrosine kinase | Age | Tyrosine | Young adults | Genomic analysis | Acute lymphatic leukemia | Stat5 protein | Lymphatic leukemia | Gene expression | Philadelphia chromosome | Interleukin 7 receptors | Thymic stromal lymphopoietin | Lymphocytes B
Journal Article
Nature Communications, ISSN 2041-1723, 11/2016, Volume 7, Issue 1, p. 13331
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2019, Volume 51, Issue 2, pp. 296 - 307
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 06/2014, Volume 94, Issue 6, pp. 805 - 808
Journal Article
Blood, ISSN 0006-4971, 06/2017, Volume 129, Issue 25, pp. 3352 - 3361
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 02/2016, Volume 29, Issue 2, pp. 186 - 200
Journal Article
Cancer Research, ISSN 0008-5472, 01/2006, Volume 66, Issue 1, pp. 134 - 142
Journal Article
Blood, ISSN 0006-4971, 08/2018, Volume 132, Issue 8, pp. 815 - 824
Key Points The prevalence of Ph-like ALL is lower in children with NCI SR ALL compared with HR ALL. Ph-like ALL in SR patients harbors few targetable kinase... 
Lymphoid Neoplasia | 100
Journal Article
Molecular Genetics & Genomic Medicine, ISSN 2324-9269, 03/2015, Volume 3, Issue 2, pp. 99 - 110
Current practice by clinical diagnostic laboratories is to utilize online prediction programs to help determine the significance of novel variants in a given... 
prediction | pathogenicity | variants | Diagnostics | sequencing | GENETICS & HEREDITY | Muscular dystrophy | Pathogens | Laboratories | Datasets | Studies | Pathogenicity | Data sets | Predictions | On-line programming | Diagnostic systems | Dystrophy | Mutation | Internet | Performance measurement | Method
Journal Article
Journal Article
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