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PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0123313 - e0123313
Metabolic syndrome (MetS) is among the most important public health problems worldwide, and is recognized as a major risk factor for various illnesses,... 
RHEUMATOID-ARTHRITIS | DIABETES-MELLITUS | OXIDATIVE STRESS | NAD(P)H-QUINONE OXIDOREDUCTASE-1 | MICROSATELLITE REPEATS | ENDOTHELIAL DYSFUNCTION | CARBON-MONOXIDE | C609T POLYMORPHISM | MULTIDISCIPLINARY SCIENCES | HEME OXYGENASE-1 GENE | CHINESE POPULATION | Heme Oxygenase-1 - genetics | Gene Frequency - genetics | Genetic Predisposition to Disease | Genetic Association Studies | Metabolic Syndrome - genetics | Humans | Polymorphism, Single Nucleotide - genetics | Adult | Female | Male | Mexico | NAD(P)H Dehydrogenase (Quinone) - genetics | Oxidative stress | Quinone oxidoreductase | Disease | Laboratories | Oxidoreductase | Health problems | Genes | Fluorescence | Population studies | Arthritis | Fluorescent indicators | Glucose | Metabolic syndrome | Population genetics | Blood | Risk factors | Antioxidants | Body mass index | Demographics | Illnesses | NADH | Rodents | Heme | Blood pressure | Lipoproteins (high density) | Heart diseases | Deoxyribonucleic acid--DNA | Public health | Stresses | Hypertension | Medical research | Obesity | Diabetes mellitus | Quinone | Triglycerides | Cholesterol | Stress | Abdomen | Oxygenase | Genotyping | Gene frequency | Hypertriglyceridemia | Alleles | Nicotinamide adenine dinucleotide | Diabetes | Cardiovascular diseases | Metabolic disorders | Polymorphism | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
by Williams Amy, A.L and Jacobs Suzanne, S.B.R and Moreno-Macías, Hortensia and Huerta-Chagoya, Alicia and Churchhouse, Claire and Márquez-Luna, Carla and Gómez-Vázquez, María José and Burtt Noël, N.P and Aguilar-Salinas, Carlos A and González-Villalpando, Clicerio and Florez, Jose C and Orozco, Lorena and Tusié-Luna, Teresa and Altshuler, David and Ripke, Stephan and Manning, Alisa K and García-Ortíz, Humberto and Neale, Benjamin and Reich, David and Stram, Daniel O and Fernández-López, Juan Carlos and Romero-Hidalgo, Sandra and Patterson, Nick and Haiman, Christopher A and Aguilar-Delfín, Irma and Martínez-Hernández, Angélica and Centeno-Cruz, Federico and Mendoza-Caamal, Elvia and Revilla-Monsalve, Cristina and Islas-Andrade, Sergio and Córdova, Emilio and Rodríguez-Arellano, Eunice and Soberón, Xavier and Florez Jose, J.C and González-Villalpando María Elena, M.A and Henderson, Brian E and Monroe, Kristine and Wilkens, Lynne and Kolonel, Laurence N and Le Marchand, Loic and Riba, Laura and Ordóñez-Sánchez María Luisa, M.A and Rodríguez-Guillén, Rosario and Cruz-Bautista, Ivette and Rodríguez-Torres, Maribel and Muñoz-Hernández, Linda Liliana and Sáenz, Tamara and Gómez, Donají and Alvirde, Ulices and Onofrio, Robert C and Brodeur, Wendy M and Gage, Diane and Murphy, Jacquelyn and Franklin, Jennifer and Mahan, Scott and Ardlie, Kristin and Crenshaw, Andrew T and Winckler, Wendy and Prüfer, Kay and Shunkov, Michael V and Sawyer, Susanna and Stenzel, Udo and Kelso, Janet and Lek, Monkol and Sankararaman, Sriram and MacArthur, Daniel G and Derevianko, Anatoli P and Pääbo, Svante and Jacobs, Suzanne B.R and Gopal, Shuba and Grammatikos, James A and Smith, Ian C and Bullock, Kevin H and Deik, Amy A and Souza, Amanda L and Pierce, Kerry A and Clish, Clary B and Fennell, Timothy and Farjoun, Yossi and Gabriel, Stacey and Gross, Myron D and Pereira, Mark A and Seielstad, Mark and Koh, Woon-Puay and Tai, E-Shyong and Flannick, Jason and Fontanillas, Pierre and Morris, Andrew and Teslovich, Tanya M and Atzmon, Gil and Blangero, John and Bowden, Donald W and Chambers, John and Cho, Yoon Shin and Duggirala, Ravindranath and Glaser, Benjamin and Hanis, Craig and Kooner, Jaspal and Laakso, Markku and Lee, Jong-Young and ... and SIGMA Type 2 Diabet Consortium and Broad Genomics Platform and T2D-GENES Consortium and SIGMA Type 2 Diabetes Consortium and The SIGMA Type 2 Diabetes Consortium
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7486, pp. 97 - 101
Journal Article
Journal Article
by Flannick, Jason and Mercader, Josep M and Fuchsberger, Christian and Udler, Miriam S and Mahajan, Anubha and Wessel, Jennifer and Teslovich, Tanya M and Caulkins, Lizz and Koesterer, Ryan and Barajas-Olmos, Francisco and Blackwell, Thomas W and Boerwinkle, Eric and Brody, Jennifer A and Centeno-Cruz, Federico and Chen, Ling and Chen, Siying and Contreras-Cubas, Cecilia and Córdova, Emilio and Correa, Adolfo and Cortes, Maria and DeFronzo, Ralph A and Dolan, Lawrence and Drews, Kimberly L and Elliott, Amanda and Floyd, James S and Gabriel, Stacey and Garay-Sevilla, Maria Eugenia and García-Ortiz, Humberto and Gross, Myron and Han, Sohee and Heard-Costa, Nancy L and Jackson, Anne U and Jørgensen, Marit E and Kang, Hyun Min and Kelsey, Megan and Kim, Bong-Jo and Koistinen, Heikki A and Kuusisto, Johanna and Leader, Joseph B and Linneberg, Allan and Liu, Ching-Ti and Liu, Jianjun and Lyssenko, Valeriya and Manning, Alisa K and Marcketta, Anthony and Malacara-Hernandez, Juan Manuel and Martínez-Hernández, Angélica and Matsuo, Karen and Mayer-Davis, Elizabeth and Mendoza-Caamal, Elvia and Mohlke, Karen L and Morrison, Alanna C and Ndungu, Anne and Ng, Maggie C. Y and O’Dushlaine, Colm and Payne, Anthony J and Pihoker, Catherine and Post, Wendy S and Preuss, Michael and Psaty, Bruce M and Vasan, Ramachandran S and Rayner, N. William and Reiner, Alexander P and Revilla-Monsalve, Cristina and Robertson, Neil R and Santoro, Nicola and Schurmann, Claudia and So, Wing Yee and Soberón, Xavier and Stringham, Heather M and Strom, Tim M and Tam, Claudia H. T and Thameem, Farook and Tomlinson, Brian and Torres, Jason M and Tracy, Russell P and van Dam, Rob M and Vujkovic, Marijana and Wang, Shuai and Welch, Ryan P and Witte, Daniel R and Wong, Tien-Yin and Atzmon, Gil and Barzilai, Nir and Blangero, John and Bonnycastle, Lori L and Bowden, Donald W and Chambers, John C and Chan, Edmund and Cheng, Ching-Yu and Cho, Yoon Shin and Collins, Francis S and de Vries, Paul S and Duggirala, Ravindranath and Glaser, Benjamin and Gonzalez, Clicerio and Gonzalez, Ma Elena and Groop, Leif and Kooner, Jaspal Singh and Kwak, Soo Heon and ... and DiscovEHR Collaboration and ESP and GoT2D and SIGMA-T2D and Broad Genomics Platform and AMP-T2D-GENES and LuCamp and T2D-GENES and CHARGE and ProDiGY
Nature, ISSN 0028-0836, 06/2019, Volume 570, Issue 7759, pp. 71 - 76
Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to disease pathogenesis. Here we report exome-sequencing analyses of... 
Type 2 diabetes | Genetic research | Genetic aspects | Research | Exome sequencing | Medical colleges | Analysis | Diabetes therapy | Sequences | Disease | Pathogenesis | Genes | Diabetes mellitus | Hispanic Americans | Health risks | Genomes | Epidemiology | Disease control | Studies | Proteins | Genetic variance | Gene frequency | Alleles | Heritability | Gene loci | Diabetes | Diabetes mellitus (non-insulin dependent) | Power
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 11552 - 11
Protein folding is a process of self-assembly defined by the sequence of the amino acids of the protein involved. Additionally, proteins tend to unfold,... 
INSULIN | IMPLIES | ASSEMBLIES | AMYLIN | MULTIDISCIPLINARY SCIENCES | ISLET AMYLOID POLYPEPTIDE | COMMON MECHANISM | TOXICITY | IAPP | OLIGOMERS | TRANSGENIC MICE | Oligomerization | Self-association | Streptozocin | Diabetes mellitus | Hexamers | Amylin | Proteins | Self-assembly | Protein folding | Rodents | β-Amyloid | Diabetes | Pancreas | Index Medicus
Journal Article
by Mercader, Josep M and Liao, Rachel G and Bell, Avery D and Dymek, Zachary and Estrada, Karol and Tukiainen, Taru and Huerta-Chagoya, Alicia and Moreno-Macías, Hortensia and Jablonski, Kathleen A and Hanson, Robert L and Walford, Geoffrey A and Moran, Ignasi and Chen, Ling and Agarwala, Vineeta and Ordoñez-Sánchez, María Luisa and Rodríguez-Guillen, Rosario and Rodríguez-Torres, Maribel and Segura-Kato, Yayoi and García-Ortiz, Humberto and Centeno-Cruz, Federico and Barajas-Olmos, Francisco and Caulkins, Lizz and Puppala, Sobha and Fontanillas, Pierre and Williams, Amy L and Bonàs-Guarch, Sílvia and Hartl, Chris and Ripke, Stephan and Tooley, Katherine and Lane, Jacqueline and Zerrweck, Carlos and Martínez-Hernández, Angélica and Córdova, Emilio J and Mendoza-Caamal, Elvia and Contreras-Cubas, Cecilia and González-Villalpando, María E and Cruz-Bautista, Ivette and Muñoz-Hernández, Liliana and Gómez-Velasco, Donaji and Alvirde, Ulises and Henderson, Brian E and Wilkens, Lynne R and Le Marchand, Loic and Arellano-Campos, Olimpia and Riba, Laura and Harden, Maegan and Gabriel, Stacey and Abboud, Hanna E and Cortes, Maria L and Revilla-Monsalve, Cristina and Islas-Andrade, Sergio and Soberon, Xavier and Curran, Joanne E and Jenkinson, Christopher P and DeFronzo, Ralph A and Lehman, Donna M and Hanis, Craig L and Bell, Graeme I and Boehnke, Michael and Blangero, John and Duggirala, Ravindranath and Saxena, Richa and MacArthur, Daniel and Ferrer, Jorge and McCarroll, Steven A and Torrents, David and Knowler, William C and Baier, Leslie J and Burtt, Noel and González-Villalpando, Clicerio and Haiman, Christopher A and Aguilar-Salinas, Carlos A and Tusié-Luna, Teresa and Flannick, Jason and Jacobs, Suzanne B R and Orozco, Lorena and Altshuler, David and Florez, Jose C and Broad Genomics Platform and SIGMA T2D Genetics Consortium and Diabet Prevent Program Res Grp and T2D-GENES Consortium and Diabetes Prevention Program Research Group
Diabetes, ISSN 0012-1797, 11/2017, Volume 66, Issue 11, pp. 2903 - 2914
Journal Article
JAMA, ISSN 0098-7484, 06/2014, Volume 311, Issue 22, pp. 2305 - 2314
Journal Article